Van-Chr-Zin Concentrate Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Van-Chr-Zin Concentrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Van-Chr-Zin Concentrate is a dietary supplement by Complete H2O Minerals with 4 active ingredients. Its ingredients are commonly taken for zinc deficiency, immune support, cold symptoms.Based on those ingredients, 307 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vanadium, Chromium, Zinc. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Van-Chr-Zin Concentrate by Complete H2O Minerals
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HelloPharmacist Scorecard of Van-Chr-Zin Concentrate by Complete H2O Minerals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Van-Chr-Zin Concentrate contains 4 active ingredients: zinc, chromium, vanadium, and chloride. Zinc supports immune function and wound healing; chromium helps regulate blood sugar; and vanadium plays a role in glucose metabolism.
The product is supplied as a liquid, which can make dosing flexible. Several inactive ingredients—purified water, vanadium chloride, chromium chloride, and zinc chloride—are present as well.
Does it work?
Strong evidence
Zinc is effective for treating zinc deficiency and likely effective for Wilson disease (a copper metabolism disorder). It's possibly effective for acne, acrodermatitis enteropathica (a rare absorption disorder), age-related macular degeneration, and diabetes.
Chromium is likely effective for chromium deficiency and possibly effective for diabetes, though it appears possibly ineffective for prediabetes, schizophrenia, and high blood pressure. Vanadium is likely effective for vanadium deficiency, but evidence for athletic performance, cancer, diabetes, and high cholesterol is insufficient to rate its benefit.
How safe is it?
Well-documented data
Zinc is generally well tolerated at recommended doses below 40 mg daily for adults, though higher amounts can be harmful. Common side effects at higher doses include stomach cramps, diarrhea, metallic taste, nausea, and vomiting.
Long-term high-dose zinc may increase copper deficiency risk, potentially causing anemia and low white blood cell counts. Chromium is usually well tolerated at typical supplement doses, with occasional headaches, insomnia, irritability, or mood changes; high or long-term doses carry limited safety data and possible kidney or liver concerns.
Vanadium is well tolerated below 1.8 mg daily but can cause stomach upset, diarrhea, and nausea at higher doses; long-term high doses may damage the kidneys. No pregnancy or breastfeeding safety data are on file for any of these three active ingredients—talk with your doctor or pharmacist before use if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist if you're on quinolone antibiotics (ciprofloxacin, levofloxacin, others), cephalexin, tetracycline antibiotics, penicillamine, ritonavir, integrase inhibitors, cisplatin, levothyroxine, antidiabetes drugs, insulin, blood thinners or antiplatelet drugs, NSAIDs, or aspirin. The product may reduce the effectiveness of antibiotics and thyroid hormone, increase low-blood-sugar risk, or raise bleeding risk depending on what you're taking.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is appropriate for people with documented zinc, chromium, or vanadium deficiency or those whose doctor has recommended it for diabetes or macular degeneration support. If you take any antibiotic, thyroid medication, blood thinner, antidiabetes drug, or HIV medication, check your specific prescriptions with the tool below before starting.
Talk to your pharmacist or doctor to confirm the right dose and spacing for your medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Van-Chr-Zin Concentrate, straight from the product label.
| Brand | Complete H2O Minerals |
|---|---|
| Barcode (UPC) | 188671000243 |
| Net contents | 16 Oz(s); 1 Pint(s); 473 mL |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 252094 |
| Product type | Mineral |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Children (All) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Van-Chr-Zin Concentrate by Complete H2O Minerals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Zinc | 0.75 mg | 5% |
| Chromium | 0.25 mg | 125% |
| Vanadium | 0.5 mg | 2000% |
| Chloride | 2.3 mg | -- |
Other ingredients: purified Water, Vanadium Chloride, Chromium Chloride, Zinc Chloride
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Van-Chr-Zin is a blend of vanadium, which helps regulate HDL (good cholesterol) in the brain, spinal cord, and nervous system; chromium, which helps increase the body's sensitivity to the hormone insulin for efficient utilization of surplus glucose; and zinc, which is necessary for tissue repair and growth, as well as playing a key role in good vision.
Suggested/Recommended/Usage/Directions
Mixing Instructions: Mix with 8 to 10 ounces of juice or water.
Recommended Dosage: Adults: 1 Tbsp. 1500 mg Children: 1 Tsp 750 mg or as recommended by a health care professional.
General Statements
In processing, FDA & GMP guidelines are observed and strictly followed.
Quality products for a quality life!
FDA Disclaimer Statement
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, prevent or cure any disease.
FDA Statement of Identity
Dietary Supplement
Storage
For best results, store in a cool, dark place and use within six months.
Precautions
Note: Do not use if tamper seal is broken or missing.
Formulation
Complete H2O Minerals contain no fillers, or artificial ingredients.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Van-Chr-Zin Concentrate by Complete H2O Minerals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Van-Chr-Zin Concentrate by Complete H2O Minerals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size15 mL Dosage formLiquid Servings per container32 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Zinc
Interacts with67 drugs
Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...
Zinc monograph & interactionsChromium
Interacts with178 drugs
Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...
Chromium monograph & interactionsVanadium
Interacts with208 drugs
Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...
Vanadium monograph & interactionsChloride
Other (inactive) ingredients: Purified Water, Vanadium Chloride, Chromium Chloride, Zinc Chloride. These complete the product’s ingredient list but are not active constituents.
Van-Chr-Zin Concentrate by Complete H2O Minerals Drug Interactions
HelloPharmacist Interaction Report
Van-Chr-Zin Concentrate by Complete H2O Minerals contains three active minerals—zinc, chromium, and vanadium—that together interact with a significant number of medications.
The most serious interaction involves zinc and quinolone antibiotics (like ciprofloxacin and levofloxacin); zinc forms complexes in your gut that block the antibiotic's absorption, reducing its effectiveness. You'll need to space them at least 2 hours apart, with zinc taken after the antibiotic.
Read the full breakdown — every affected drug type, severity by severity
Zinc also interacts moderately with several other antibiotics, including cephalexin (Keflex) and tetracyclines, as well as penicillamine (Cuprimine, Depen), ritonavir (Norvir, an HIV medication), integrase inhibitors for HIV, and the combination drug bictegravir/emtricitabine/tenofovir alafenamide (Biktarvy). Theoretically, zinc may also interfere with cisplatin, a chemotherapy drug.
Chromium interacts moderately with antidiabetes medications (including insulin) and levothyroxine (Synthroid) for thyroid function—it can lower blood sugar and reduce thyroid hormone absorption. Chromium also has minor interactions with NSAIDs and aspirin.
Vanadium interacts moderately with blood thinners and antiplatelet drugs (like warfarin and aspirin), potentially increasing bleeding risk, and with antidiabetes drugs, raising low-blood-sugar risk.
Allow at least 2 hours before or 4–6 hours after taking zinc with most antibiotics; the same timing applies to levothyroxine and some HIV medications. Altogether, these interactions span 304 individual medications.
Use the medication checker on this page to confirm your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Van-Chr-Zin Concentrate?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Van-Chr-Zin Concentrate interact with 307 drugs. Click any drug to see the details.
3 of the 4 ingredients in Van-Chr-Zin Concentrate interact with drugs. Each result below shows which ingredient is responsible. Vanadium Chromium Zinc
AbciximabReoPro
How Abciximab interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Acarbose interactionChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acetaminophen, Aspirin interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acetaminophen, Aspirin, Caffeine interactionChromiumAspirin, Nonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
Theoretically, aspirin might increase chromium absorption.
Read the full Chromium + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acetaminophen, Ibuprofen interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Acetohexamide interactionVanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acetylsalicylic Acid interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Albiglutide interactionVanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Alogliptin interactionChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Alogliptin, Metformin interactionVanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Alogliptin, Pioglitazone interactionChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
ZincTetracycline Antibiotics Moderate
Interaction Summary
Zinc might reduce levels of tetracycline antibiotics.
Read the full Zinc + Amphotericin, Tetracycline interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Van-Chr-Zin Concentrate — through 1 ingredient. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin, Butalbital interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin, Butalbital, Caffeine interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Van-Chr-Zin Concentrate — through 2 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin, Butalbital, Caffeine, Phenacetin interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Butalbital, Caffeine, Phenacetin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Van-Chr-Zin Concentrate with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vanadium
Anticoagulant/Antiplatelet Drugs
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.
Antidiabetes Drugs
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.
Chromium
Antidiabetes Drugs
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.
Insulin
Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,
Levothyroxine (Synthroid, Others)
Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.
Aspirin
Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.
Zinc
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.
Cephalexin (Keflex)
Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.
Cisplatin (Platinol-Aq)
Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.
Integrase Inhibitors
Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.
Penicillamine (Cuprimine, Depen)
Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.
Quinolone Antibiotics
Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.
Ritonavir (Norvir)
Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.
Tetracycline Antibiotics
Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.
Amiloride (Midamor)
Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.
Atazanavir (Reyataz)
Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.
Brand information
Manufacturer and brand details for Van-Chr-Zin Concentrate, from the product label.
Complete H2O Minerals
See all Complete H2O Minerals products- Name
- Complete H2O Minerals
- Street Address
- 1167 West 3050 South
- City
- Ogden
- State
- UT
- ZipCode
- 84401
- Phone Number
- 1.877.646.3725
- Web Address
- www.completeh2ominerals.com
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The Full Monographs Behind Van-Chr-Zin Concentrate’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Zinc
Interacts with 67 drugsZinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...
Read the full Zinc monograph → Herb & supplement monographChromium
Interacts with 178 drugsChromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...
Read the full Chromium monograph → Herb & supplement monographVanadium
Interacts with 208 drugsVanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and...
Read the full Vanadium monograph →Sources & How We Checked
Van-Chr-Zin Concentrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 156 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Zinc 88 references
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- Blondeau JM. Expanded activity and utility of the new fluoroquinolones: a review. Clin Ther 1999;21:3-40. PubMed
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- Hebel SK, ed. Drug Facts and Comparisons. 52nd ed. St. Louis: Facts and Comparisons, 1998.
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- Seelig MS. Auto-immune complications of D-penicillamine - A possible result of zinc and magnesium depletion and of pyridoxine inactivation. J Am Coll Nutr 1982;1:207-14. PubMed
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- Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. AREDS report no. 8. Arch Oph
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- GlaxoSmithKline Consumer Advisory. GlaxoSmithKline (GSK) warns about a potential health risk associated with long-term, excessive use of GSK's zinc-containing denture adhesives Super Polygrip Original, Ultra Fresh and Extra Care. February 18, 2010. Availa
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