Major interaction on record — check this product against your medications before combining. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Women's Balance Ingredients & Drug Interactions

by Douglas Cooper Co.

Women's Balance label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Women's Balance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Women's Balance is a dietary supplement by Douglas Cooper Co. with 6 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 497 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Borage Oil powder, Vitamin B6, Dong Quai. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Women's Balance by Douglas Cooper Co.

Ask about any prescription or over-the-counter medication and we check it for interactions with Women's Balance by Douglas Cooper Co. — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Women's Balance by Douglas Cooper Co.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “Borage Oil powder” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.

Women's Balance contains 6 active ingredients. Vitamin B6 is included to support healthy blood levels and nerve function — it's proven effective for sideroblastic anemia and B6 deficiency, and possibly helpful for pregnancy-related nausea.

Dong quai is a traditional herb used historically for women's health, though we don't have solid evidence it works for the conditions listed on the label. Folate supports cellular function.

Wild yam extract and chaste berry tree extract are botanical ingredients often used in women's formulas, though evidence for their effectiveness is either limited or shows they may not work as intended. The product also contains gamma-linolenic acid and borage oil powder as additional botanical components.

Beyond these actives, the capsules include inactive ingredients like cellulose, rice flour, magnesium stearate, and silica as binders and fillers, plus black cohosh extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promote healthy feminine balance.
  • We looked for evidence on: Dysmenorrhea, Menopausal symptoms, Postmenopausal conditions, Premenstrual syndrome (PMS), Rheumatoid arthritis (RA), Atopic dermatitis (eczema) — and 4 related terms.
  • The strongest evidence on file: Vitamin B6 is rated "Possibly Effective" for Premenstrual syndrome (PMS) (Natural Medicines).
  • Also on file: Vitex Agnus-castus is rated "Possibly Effective" for Premenstrual syndrome (PMS).
  • Also on file: Wild Yam is rated "Possibly Ineffective" for Menopausal symptoms.

Vitamin B6 in this product is effective for sideroblastic anemia and B6 deficiency, and is possibly effective for pregnancy-induced nausea and vomiting — though use in pregnancy requires a doctor's oversight. It's also likely effective for lowering high homocysteine levels.

For the other ingredients, the evidence picture is much less clear. Dong quai, wild yam extract, and chaste berry tree extract all show insufficient reliable evidence to rate them for their intended uses — meaning we simply don't have solid research backing their effectiveness for the conditions this product targets.

Wild yam is actually rated possibly ineffective for menopausal symptoms. Gamma-linolenic acid and folate's effectiveness ratings aren't in our data for the conditions this product addresses.

The evidence, ingredient by ingredient Vitamin B6 Dong Quai Borage Wild Yam Vitex Agnus-castus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is well tolerated at doses under 100 mg daily. At higher doses over time, it can cause nerve damage (sensory neuropathy) — doses over 1,000 mg daily or total lifetime doses of 1,000 grams or more carry the highest risk, though neuropathy can happen at lower doses too.

Common side effects at any dose are headache, nausea, and heartburn. We don't have pregnancy or breastfeeding safety data on file for vitamin B6 in this product.

Dong quai should be avoided during pregnancy because it may stimulate the uterus and affect bleeding. It's also best avoided while breastfeeding due to insufficient safety information.

It can increase your sensitivity to sunlight and raise bleeding risk overall. Wild yam also lacks enough safety data — avoid it during pregnancy and while breastfeeding.

Both ingredients are generally well tolerated in short-term use otherwise, though wild yam can cause fever, headache, upset stomach, and rarely anaphylaxis. We have no pregnancy or breastfeeding data for gamma-linolenic acid or chaste berry tree extract.

Side effects, ingredient by ingredient Vitamin B6 Dong Quai Borage Wild Yam Vitex Agnus-castus

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Vitamin B6, Dong Quai, Vitex Agnus-castus, Wild Yam.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; Parkinson's medications.
  • For scale: 442 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take warfarin or any blood thinner or antiplatelet drug — dong quai raises bleeding risk. Blood pressure medications, the heart drug amiodarone, seizure medications (phenobarbital, phenytoin), levodopa (especially without carbidopa), and estrogen-based hormone therapy all interact with ingredients here.

No interactions are documented for gamma-linolenic acid, folate, or chaste berry tree extract — we hold no data on those ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you take warfarin or other blood thinners, blood pressure medications, seizure drugs, levodopa, or hormone therapy, talk with your pharmacist or doctor before starting this product — the interaction risks are real. Vitamin B6 is proven helpful for certain deficiencies and possibly for morning sickness under medical guidance, but dong quai and wild yam lack solid evidence they work for what this product claims.

Avoid this product if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Women's Balance, straight from the product label.

Brand Douglas Cooper Co.
Net contents 90 Veg Capsule(s)
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 247452
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Women's Balance by Douglas Cooper Co., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
90
IngredientAmount% DV
Vitamin B617 mg850%
Gamma-Linolenic Acid15 mg--
Folate133 mcg33%
Dong Quai100 mg--
Borage Oil powder100 mg--
Wild Yam extract75 mg--
Chaste Berry tree (Vitex) extract50 mg--

Other ingredients: Cellulose, Rice Flour, Magnesium Stearate, Silica, Black Cohosh extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 capsule 3 times daily, preferably with food.

Formula

This product is a unique herbal support formula for women.

We have combined standardized herbal extracts of Wild Yam and Vitex with nutritional support from dong Quai, GLA, Vitamin B-6 and Folic Acid to promote a healthy feminine balance.

Women's Balance With wild yam, vitex, dong quai and GLA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if taking medication or have a medical condition. This product should not be consumed during the first week of menstrual period. Not intended for pregnant or nursing women.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

To report a serious adverse event, or for product information, contact 1-800-234-8686

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Storage

Store in a cool, dry place after opening.

General Statements

Please recycle.

Douglas Cooper Co. "Trace Miner Make the Difference" Since 1950

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Women's Balance by Douglas Cooper Co. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Women's Balance label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Women's Balance by Douglas Cooper Co.

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
17 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Folate

133 mcg per serving Form: Folic Acid

Dong Quai

Interacts with
163 drugs
100 mg per serving

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scienti...

Dong Quai monograph & interactions

Borage Oil powder

Interacts with
226 drugs
100 mg per serving

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arth...

Borage Oil powder monograph & interactions
  • › Gamma-Linolenic Acid

Wild Yam extract

Interacts with
41 drugs
75 mg per serving Form: Diosgenin

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for t...

Wild Yam extract monograph & interactions

Chaste Berry tree (Vitex) extract

Interacts with
121 drugs
50 mg per serving Form: Agnusides

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS sympto...

Chaste Berry tree (Vitex) extract monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Flour, Magnesium Stearate, Silica, Black Cohosh extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Women's Balance by Douglas Cooper Co. Drug Interactions

Want to check YOUR meds against Women's Balance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
497Drugs
2 Major 495 Moderate

Ingredients driving the most interactions

Borage Oil powder 226
Vitamin B6 210
Dong Quai 163
Chaste Berry tree (Vitex) extract 121
Wild Yam extract 41

Individual Drug Interactions

The ingredients in Women's Balance interact with 497 drugs. Click any drug to see the details.

5 of the 6 ingredients in Women's Balance interact with drugs. Each result below shows which ingredient is responsible. Borage Oil powder Vitamin B6 Dong Quai Chaste Berry tree (Vitex) extract Wild Yam extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Women's Balance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Borage Oil powder3 drug types · 226 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.

Likelihood Possible Evidence D
Borage Oil powder full monograph & interactions

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Dong Quai3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Dong Quai full monograph & interactions

Chaste Berry tree (Vitex) extract5 drug types · 121 drugs

Antipsychotic Drugs

Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as antipsychotic drugs due to its dopamine agonist effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Vitex agnus-castus might interfere with the efficacy of oral contraceptives due to possible hormone modulating activity.

Likelihood Possible Evidence B
Dopamine Agonists

Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Vitex agnus-castus might potentiate the actions of dopaminergic agonists due to possible dopaminergic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, vitex agnus-castus could interfere with the activity of estrogens.
Vitex agnus-castus has hormone modulating activity that can interfere with the efficacy of hormone replacement therapy.

Likelihood Probable Evidence D
Metoclopramide (Reglan)

Theoretically, dopaminergic effects of vitex agnus-castus could interfere with metoclopramide.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as metoclopramide due to its possible dopaminergic effects.

Likelihood Possible Evidence D
Chaste Berry tree (Vitex) extract full monograph & interactions

Wild Yam extract1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Wild Yam extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Women's Balance, from the product label.

Douglas Cooper Co.

See all Douglas Cooper Co. products
Name
Douglas Cooper Co.
City
Carmel
State
IN
ZipCode
46032
Phone Number
1-800-234-8686
Pharmacist Counseling Corner

Women's Balance by Douglas Cooper Co.: Common Questions

Does Women's Balance by Douglas Cooper Co. interact with any medications?
Yes. Based on its ingredients, Women's Balance has a known interaction with 497 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Women's Balance contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — dong quai and wild yam should both be avoided during pregnancy and breastfeeding because there isn't enough safety data. Vitamin B6 at standard supplement doses is often used for morning sickness, but only under a doctor's guidance. Talk with your OB or pharmacist before using this product while pregnant or nursing.
Is vitamin B6 safe at high doses?
Vitamin B6 is well tolerated below 100 mg daily, but high doses over time can damage nerves (sensory neuropathy). Doses over 1,000 mg daily carry the most risk, though neuropathy can occur at lower doses with long-term use. Stick to the product's recommended dose and don't exceed it.
Does this product actually work for women's health?
Vitamin B6 is proven effective for B6 deficiency and sideroblastic anemia, and possibly helps with pregnancy-related nausea under medical supervision. For the other ingredients — dong quai, wild yam, and chaste berry tree extract — we don't have solid research showing they work for the conditions this product targets. Wild yam is actually possibly ineffective for menopausal symptoms.
What are the most common side effects?
From vitamin B6: headache, nausea, and heartburn at normal doses. Dong quai can cause burping and bloating, and increases your skin's sensitivity to sunlight. Wild yam may cause fever, headache, upset stomach, and vomiting. Serious side effects are rare but possible — nerve damage from high-dose B6 and anaphylaxis from wild yam are documented.
Why does this product interact with so many medications?
Dong quai contains compounds similar to blood thinners and can affect how your body uses estrogen, which is why it interacts with warfarin, other anticoagulants, and hormone therapy. Vitamin B6 can lower blood pressure and change how your liver breaks down seizure medications and certain other drugs. These are real effects, which is why you need to check your specific medications before starting.
Can I take this with birth control or hormone replacement therapy?
Not without checking first. Both dong quai and wild yam have estrogenic effects and theoretically could interfere with how your estrogen-based therapy works. Talk with your pharmacist or doctor about whether this product is right for you if you're on any hormone therapy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Women's Balance label
Go deeper

The Full Monographs Behind Women's Balance’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph → Herb & supplement monograph

Borage

Interacts with 226 drugs

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...

Read the full Borage monograph → Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph → Herb & supplement monograph

Vitex Agnus-castus

Interacts with 121 drugs

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS symptoms. It is generally well tolerated by ma...

Read the full Vitex Agnus-castus monograph →
Sources

Sources & How We Checked

Women's Balance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 92 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
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Dong Quai 19 references
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Borage 11 references
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Wild Yam 7 references
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Vitex Agnus-castus 23 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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