ZenBiotic Ingredients & Drug Interactions
by EntheoZen
What is this page for?
First and foremost: checking ZenBiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ZenBiotic is a dietary supplement by EntheoZen with 12 active ingredients. Its ingredients are commonly taken for digestive health and bloating, diarrhea support, immune support.Based on those ingredients, 268 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus subtilis DE111, Bacillus coagulans Lactospore, Inulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against ZenBiotic by EntheoZen
Ask about any prescription or over-the-counter medication and we check it for interactions with ZenBiotic by EntheoZen — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
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HelloPharmacist Scorecard of ZenBiotic by EntheoZen
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 2 of its 12 active ingredients.
- “Proprietary Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
- “PreforPro Phage Complex” is a proprietary blend — the label gives one combined amount (15 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 3 of the 4 matched ingredients can interact with medications — Inulin, Bacillus Coagulans, Bacillus Subtilis.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: diabetes medications.
- For scale: 268 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 4 of 4.
- General safety write-ups exist for 4 of 4.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 4 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ZenBiotic, straight from the product label.
| Brand | EntheoZen |
|---|---|
| Barcode (UPC) | 863124000130 |
| Net contents | 60 Delayed Release Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Nov 19, 2021 |
| DSLD ID | 256279 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ZenBiotic by EntheoZen, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactobacillus brevis Lbr-35 | 0 NP | -- |
| Lactobacillus rhamnosus Lr-32 | 0 NP | -- |
| Lactobacillus plantarum Lp-115 | 0 NP | -- |
| Bacillus subtilis DE111 | 0 NP | -- |
| LH01 - Myoviridae | 0 NP | -- |
| LL5 - Siphoviridae | 0 NP | -- |
| T4D - Myoviridae | 0 NP | -- |
| LL12 - Myoviridae | 0 NP | -- |
| Proprietary Probiotic Blend | 0 NP | -- |
| Inulin | 200 mg | -- |
| NutraFlora | 200 mg | -- |
| Bacillus coagulans Lactospore | 0 NP | -- |
| Bifidobacterium animalis lactis VK2 | 0 NP | -- |
| PreforPro Phage Complex | 15 mg | -- |
Other ingredients: Rice Dextrin, Vegetable Capsule, Medium Chain Triglycerides
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Patented Phage technology Soil-based spore-forming species Survives stomach acid and heat
3rd party tested for purity
Dairy free
Formulated by scientists
Survives stomach acid Phage technology
Formula
Clinically studied strains Prebiotic fiber complex
Mood boosting probiotic with prebiotics
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules per day.
Storage
Refrigeration not required but recommended to maintain potency.
Seals/Symbols
Made in the USA
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
PreforPro and De111 are registered trademarks of Deerland Enzymes, Inc. LactoSpore is a registered trademark of Sabinsa.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ZenBiotic by EntheoZen label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ZenBiotic by EntheoZen
These are the 12 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Probiotic Blend
- › Lactobacillus brevis Lbr-35
- › Lactobacillus rhamnosus Lr-32
- › Lactobacillus plantarum Lp-115
- › Bacillus subtilis DE111
- › Bacillus coagulans Lactospore
- › Bifidobacterium animalis lactis VK2
Inulin
Interacts with86 drugs
Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...
Inulin monograph & interactionsNutraFlora
No knowninteractions
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...
NutraFlora monograph & interactionsPreforPro Phage Complex
- › LH01 - Myoviridae
- › LL5 - Siphoviridae
- › T4D - Myoviridae
- › LL12 - Myoviridae
Other (inactive) ingredients: Rice Dextrin, Vegetable Capsule, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.
ZenBiotic by EntheoZen Drug Interactions
ZenBiotic contains 12 ingredients, and 3 of them have known drug interactions. Altogether they interact with 268 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against ZenBiotic?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in ZenBiotic interact with 268 drugs. Click any drug to see the details.
3 of the 12 ingredients in ZenBiotic interact with drugs. Each result below shows which ingredient is responsible. Bacillus subtilis DE111 Bacillus coagulans Lactospore Inulin
Oritavancin DiphosphateKimyrsa, Orbactiv
How Oritavancin Diphosphate interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Oritavancin Diphosphate interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Oritavancin Diphosphate interactionOxacillinBactocill, Prostaphlin
How Oxacillin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Oxacillin interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Oxacillin interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Oxytetracycline interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionOzenoxacinXepi
How Ozenoxacin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Ozenoxacin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Ozenoxacin interactionParomomycin SulfateHumatin
How Paromomycin Sulfate interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Paromomycin Sulfate interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Paromomycin Sulfate interactionPenicillin GPfizerpen
How Penicillin G interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin G interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin G interactionPenicillin G BenzathineBicillin L-A, Permapen
How Penicillin G Benzathine interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin G Benzathine interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin G Benzathine interactionPenicillin G Benzathine, ProcaineBicillin C-R
How Penicillin G Benzathine, Procaine interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin G Benzathine, Procaine interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin G Benzathine, Procaine interactionPenicillin G PotassiumPen-Tids, Pentids, Pentids 400, Pentids 800, Wycillin
How Penicillin G Potassium interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin G Potassium interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin G Potassium interactionPenicillin G, ProcainePenicillin G Procaine
How Penicillin G, Procaine interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin G, Procaine interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin G, Procaine interactionPenicillin VPen-Vee
How Penicillin V interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin V interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin V interactionPenicillin V PotassiumBeepen-VK, Ledercillin, Pen VK, Pen-Vee K, V-Cillin K, Veetids
How Penicillin V Potassium interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin V Potassium interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin V Potassium interactionPenicillin VkRobicillin
How Penicillin Vk interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Penicillin Vk interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Penicillin Vk interactionPentamidinePentam 300
How Pentamidine interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Pentamidine interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Pentamidine interactionPhenazopyridine, SulfamethizoleThiosulfil-A, Thiosulfil-A Forte
How Phenazopyridine, Sulfamethizole interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Phenazopyridine, Sulfamethizole interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Phenazopyridine, Sulfamethizole interactionPhenazopyridine, SulfisoxazoleAzo-Gantrisin
How Phenazopyridine, Sulfisoxazole interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Phenazopyridine, Sulfisoxazole interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Phenazopyridine, Sulfisoxazole interactionPiperacillinPipracil
How Piperacillin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Piperacillin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Piperacillin interactionPiperacillin , TazobactamZosyn
How Piperacillin , Tazobactam interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Piperacillin , Tazobactam interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Piperacillin , Tazobactam interactionPivampicillinPondicillin
How Pivampicillin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Pivampicillin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Pivampicillin interactionPivmecillinamSelexid
How Pivmecillinam interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Pivmecillinam interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Pivmecillinam interactionPlazomicin SulfateZemdri
How Plazomicin Sulfate interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Plazomicin Sulfate interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Plazomicin Sulfate interactionPretomanidPretomanid
How Pretomanid interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Pretomanid interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Pretomanid interactionPyrazinamideTebrazid
How Pyrazinamide interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Pyrazinamide interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Pyrazinamide interactionQuinupristin, DalfopristinSynercid
How Quinupristin, Dalfopristin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Quinupristin, Dalfopristin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Quinupristin, Dalfopristin interactionRetapamulinAltabax, Altargo
How Retapamulin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Retapamulin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Retapamulin interactionRifabutinMycobutin
How Rifabutin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Rifabutin interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Rifabutin interactionRifampinRifadin, Rifadin Injection, Rimactane, Rofactor
How Rifampin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Rifampin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Rifampin interactionRifamycinAemcolo
How Rifamycin interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Rifamycin interactionBacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Rifamycin interactionRifapentinePriftin
How Rifapentine interacts with ZenBiotic — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De111 + Rifapentine interactionBacillus Coagulans LactosporeAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bacillus Coagulans Lactospore + Rifapentine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in ZenBiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bacillus subtilis DE111
Antibiotic Drugs
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.
Bacillus coagulans Lactospore
Antibiotic Drugs
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.
Inulin
Antidiabetes Drugs
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.
Brand information
Manufacturer and brand details for ZenBiotic, from the product label.
EntheoZen
See all EntheoZen products- Name
- EntheoZen LLC
- City
- San Diego
- Phone Number
- 858-848-7266
- Web Address
- www.EntheoZen.com
ZenBiotic by EntheoZen: Common Questions
Does ZenBiotic by EntheoZen interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ZenBiotic is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ZenBiotic’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bacillus Subtilis
Interacts with 182 drugsBacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...
Read the full Bacillus Subtilis monograph → Herb & supplement monographBacillus Coagulans
Interacts with 182 drugsBacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...
Read the full Bacillus Coagulans monograph → Herb & supplement monographInulin
Interacts with 86 drugsInulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...
Read the full Inulin monograph → Herb & supplement monographFructo-oligosaccharides (fos)
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...
Read the full Fructo-oligosaccharides (fos) monograph →Sources & How We Checked
ZenBiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 53 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacillus Subtilis 10 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Lampropoulos PK, Gkentzi D, Tzifas S, Dimitriou G. Neonatal sepsis due to Bacillus subtilis. Cureus 2021;13(9):e17692. PubMed
- La Jeon Y, Yang JJ, Kim MJ, et al. Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation. J Med Microbiol 2012;61(Pt 12):1766-1769. PubMed
- Wallet F, Crunelle V, Roussel-Delvallez M, Fruchart A, Saunier P, Courcol RJ. Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease. Am J Gastroenterol 1996;91(7):1477-8.
- Velasco E, Martins CA, Tabak D, Bouzas LF. "Bacillus subtilis" infection in a patient submitted to a bone marrow transplantation. Rev Paul Med 1992;110(3):116-7.
- Kato A, Yoshifuji A, Komori K, et al. A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma. J Infect Chemother 2022;28(8):1212-1215. PubMed
- Freedman KE, Hill JL, Wei Y, et al. Examining the gastrointestinal and immunomodulatory effects of the novel probiotic Bacillus subtilis DE111. Int J Mol Sci 2021;22(5):2453. PubMed
- Lefevre M, Racedo SM, Denayrolles M, et al. Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans. Regul Toxicol Pharmacol 2017;83:54-65. PubMed
- Hanifi A, Culpepper T, Mai V, et al. Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults. Benef Microbes 2015;6(1):19-27. PubMed
- Tokano M, Tarumoto N, Imai K, et al. A case of bacterial meningitis caused by Bacillus subtilis var. natto. Intern Med. 2022. Epub ahead of print.
Inulin 17 references
- Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
- Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
- Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
- Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
- Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
- Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
- Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
- Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
- Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
- Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
- Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
- Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
- Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
- Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
- Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed
Fructo-oligosaccharides (fos) 6 references
- Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
- Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
- Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
- Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed
See these in context on the Fructo-oligosaccharides (fos) monograph →
Bacillus Coagulans 20 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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