Miconazole

45 interactions 192 cited references
Also sold as: Aloe Vesta Antifungal Baza Conazol Miconazole Critic-Aid Clear Cruex Prescription Strength DermaFungal Dermagran Desenex Femmesil Fungoid Hongo Killer Ultra Inzo Lagicam Lasolex MacerRx Micaderm Micatin Micro-Guard Monistat Ony-Clear Oravig Silka Powder Tetterine Triple Paste AF Vagistat Zeasorb

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Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Deuruxolitinib Pimozide Warfarin Ifosfamide Injection Meloxicam Carvedilol
2 Contraindicated 24 Major 19 Moderate
All (45) Contraindicated (2) Major (24) Moderate (19)

Major

Miconazole Erdafitinib Balversa Increased erdafitinib exposure Details Miconazole Glimepiride Amaryl Severe hypoglycemia Details Miconazole Ifosfamide Injection Ifex Decreased ifosfamide effectiveness Details Miconazole Meloxicam Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Miconazole Meloxicam Injection Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Miconazole Amiodarone Nexterone Increased amiodarone exposure Details Miconazole Carvedilol Coreg Increased carvedilol concentrations and an increased risk of bradycardia or heart block Details Miconazole Celecoxib Celebrex Increased celecoxib exposure Details Miconazole Cilostazol Pletal® Increased cilostazol exposure Details Miconazole Domperidone Increased domperidone exposure and an increased risk of QT interval prolongation Details Miconazole Escitalopram Lexapro Increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) Details Miconazole Etonogestrel Nexplanon Increased etonogestrel exposure Details Miconazole Fosphenytoin Cerebyx Increased phenytoin or fosphenytoin (prodrug of phenytoin) exposure and an increased risk of phenytoin or fosphenytoin toxicity (a... Details Miconazole Ifosfamide Ifex Decreased ifosfamide effectiveness Details Miconazole Methadone Diskets Increased methadone exposure and an increased risk of opioid adverse effects Details Miconazole Naloxegol Movantik Increased naloxegol exposure Details Miconazole Olaparib Lynparza Increased olaparib exposure Details Miconazole Phenobarbital Fidoquel Increased PHENobarbital exposure and an increased risk of PHENobarbital-related adverse effects Details Miconazole Phenytoin Dilantin Increased phenytoin or fosphenytoin (prodrug of phenytoin) exposure and an increased risk of phenytoin or fosphenytoin toxicity (a... Details Miconazole Piperaquine Increased exposure of piperaquine Details Miconazole Primidone Mysoline Increased PHENobarbital exposure and an increased risk of PHENobarbital-related adverse effects Details Miconazole Simeprevir Olysio® Increased simeprevir exposure Details Miconazole Voriconazole Vfend Increased voriconazole exposure Details Miconazole Warfarin Coumadin Increased warfarin exposure, an increased INR and an increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.