Beta-methylphenethylamine (bmpea) + Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride
Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride brand name: Azstarys.
Beta-methylphenethylamine (bmpea) has a moderate interaction with Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride. Theoretically, taking BMPEA with other stimulant drugs might increase the risk of adverse cardiovascular effects.
Read the full interaction reportBeta-methylphenethylamine (bmpea) and Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride
Here is the interaction we found between these two, with the evidence behind it.
STIMULANT DRUGS
Why this applies to Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride
Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride falls under STIMULANT DRUGS — the group Beta-methylphenethylamine (bmpea) interacts with.
BMPEA is thought to have stimulant effects, including cardiovascular effects such as hypertension, tachycardia, and cardiac arrest.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the thing to keep in mind with Azstarys: the dexmethylphenidate part is already a stimulant that nudges up your heart rate and blood pressure. BMPEA is an amphetamine-like stimulant too, so stacking the two means you're essentially doubling up on that same kind of push on your heart and circulation.
On paper, combining them could raise your odds of side effects like a racing or pounding heartbeat, higher blood pressure, jitteriness, trouble sleeping, or chest discomfort. I'll be honest that this is a theoretical concern based on how these compounds work, not on solid human studies, so I'm not trying to scare you. Still, BMPEA isn't a well-studied or approved ingredient and often hides in weight-loss or sports supplements. I'd steer clear of it and let your doctor or pharmacist know what you're taking.
- Cohen PA, Bloszies C, Yee C, Gerona R. An amphetamine isomer whose efficacy and safety in humans has never been studied, ß-methylphenylethylamine (BMPEA), is found in multiple dietary supplements. Drug Test Anal. 2015 Apr 7. PubMed
- Brown DH, Hansson R, Oosthuizen F, et al. ß-Methylphenylethylamines: common fragmentation pathways with amphetamines in electrospray ionization collision-induced dissociation. Drug Test Anal 2016;8:344-50.
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Beta-methylphenethylamine (bmpea) Also Interacts With Other Medications
Beta-methylphenethylamine (bmpea) has 812 moderate known drug interactions in our database — the Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride one above is one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Beta-methylphenethylamine (bmpea)
We haven’t checked that one against Beta-methylphenethylamine (bmpea) yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Beta-methylphenethylamine (bmpea). Pick one to open its full report.
See Every Supplement That Interacts With Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride
This page covers Beta-methylphenethylamine (bmpea) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride page lists 92 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 10 major · 68 moderate · 14 minor.
From our pharmacist’s overview on the Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride page
“Ephedra tops my concerns for anyone taking Azstarys (serdexmethylphenidate and dexmethylphenidate), a stimulant medication for ADHD. It stacks a second stimulant onto the drug and carries a major rating for disturbing heart rhythm.”
Reviewed by 2 · Jul 18, 2026
Open the Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride interaction page
Where Beta-methylphenethylamine (bmpea) and Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,396 of 1,452 supplements looked up here in the last 7 days
#2,222 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Beta-methylphenethylamine (bmpea)
What is Beta-methylphenethylamine (bmpea)?
- Weight loss
- Pre-workout energy
- Athletic performance
- Appetite suppression
- Mental focus
Beta-methylphenethylamine (BMPEA) is a synthetic stimulant chemically similar to amphetamine that has been found in some weight-loss and sports supplements, often without being clearly listed on the label. It is not an approved or well-studied dietary ingredient, and regulators have warned that it may carry real cardiovascular risks. Because of safety concerns and the lack of human research, it is best avoided.
About Serdexmethylphenidate and Dexmethylphenidate
What Is Serdexmethylphenidate and Dexmethylphenidate Used For?
Brand name: Azstarys
Azstarys (serdexmethylphenidate/dexmethylphenidate) is approved to treat Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older. It is not recommended for children younger than 6 because they experience higher drug levels in the blood and more side effects at the same doses used in older patients.
Other Drugs & Beta-methylphenethylamine (bmpea)
Browse every other medication we’ve checked against Beta-methylphenethylamine (bmpea) — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
812 interactions
- Diltiazem ›
- Nifedipine ›
- Phentermine ›
- Hydrocortisone ›
- Methylphenidate ›
- Erythromycin ›
- Estradiol ›
- Propranolol ›
- Lidocaine ›
- Norethindrone ›
- Testosterone ›
- Verapamil ›
- Levonorgestrel ›
- Phenylpropanolamine ›
- Prednisone ›
- Quinidine ›
- Cyclosporine ›
- Dexamethasone ›
- Triazolam ›
- Zopiclone ›
- Colchicine ›
- Fentanyl ›
- Nicotine ›
- Oxybutynin ›
- Oxycodone ›
- Prednisolone ›
- Tacrolimus ›
- Temazepam ›
- Budesonide ›
- Carbamazepine ›
- Clindamycin ›
- Dextromethorphan ›
- Doxorubicin ›
- Fluticasone ›
- Formoterol ›
- Miconazole ›
- Morphine Sulfate ›
- Phenylephrine ›
- Pseudoephedrine ›
- Amphetamine ›
- Buprenorphine ›
- Conjugated Estrogens ›
- Diazepam ›
- Diethylpropion ›
- Everolimus ›
- Ivabradine ›
- Lofepramine ›
- Medroxyprogesterone ›
- Medroxyprogesterone Acetate ›
- Nortriptyline ›
- Propoxyphene ›
- Rifampin ›
- Testosterone Undecanoate ›
- Aripiprazole ›
- Caffeine (otc Drug) ›
- Ciclesonide ›
- Clonazepam ›
- Cyclobenzaprine ›
- Dapsone ›
- Desipramine ›
Showing 60 of 812 moderate interactions — see all 812 on the Beta-methylphenethylamine (bmpea) page.
No interaction 2,017 drugs checked — show the list
We also checked Beta-methylphenethylamine (bmpea) against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Ivermectin ›
- Aspirin ›
- Rosuvastatin ›
- Acetaminophen ›
- Escitalopram ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Ibuprofen ›
- Tirzepatide ›
- Semaglutide ›
- Sumatriptan ›
- Metformin ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Bendamustine ›
- Acyclovir ›
- Methotrexate ›
- Doxycycline ›
- Pregabalin ›
- Lamotrigine ›
- Azithromycin ›
- Gabapentin ›
- Isotretinoin ›
- Methylene Blue ›
- Naproxen ›
- Ciprofloxacin ›
- Levothyroxine, Liothyronine ›
- Candesartan Cilexetil ›
- Cephalexin ›
- Cyclopentolate ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Roxithromycin ›
- Mannitol ›
- Levetiracetam ›
- Pegunigalsidase Alfa-iwxj ›
- Ezetimibe ›
- Daptomycin ›
- Levothyroxine Sodium ›
- Mitomycin ›
- Valsartan ›
- Amoxicillin, Clavulanate Potassium ›
- Spironolactone ›
- Hexobarbitone ›
- Thyroid Hormone ›
- Phentermine, Topiramate ›
- Carbidopa, Levodopa ›
- Acetaminophen, Ibuprofen ›
- Factor 7a ›
- Acetaminophen, Aspirin ›
- Levodopa ›
- Minoxidil ›
- Cefaclor ›
- Lenvatinib ›
- Azelaic Acid ›
- Ibuprofen, Acetaminophen ›
- Tenecteplase ›
- Hydroxychloroquine ›
Showing the 60 most looked-up of 2,017 medications checked with no known interaction — see the full Beta-methylphenethylamine (bmpea) list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Taking Beta-methylphenethylamine (bmpea) and Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride Together: Common Questions
Can you take Beta-methylphenethylamine (bmpea) with Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride?
How serious is the Beta-methylphenethylamine (bmpea) and Serdexmethylphenidate Chloride, Dexmethylphenidate Hydrochloride interaction?
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