Drug & supplement interaction

Calcium D-glucarate + Moxidectin

Moxidectin brand name: Moxidectin.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Calcium D-glucarate and Moxidectin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Calcium D-glucarate and Moxidectin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Moxidectin and Calcium D-glucarate in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Calcium D-glucarate safety at a glance

Calcium D-glucarat... overall Use caution It appears generally well tolerated in small studies, but long-term safety in humans is not well established.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Moxidectin and Calcium D-glucarate? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Moxidectin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Moxidectin is filed under a single classification — oral drugs. Calcium D-glucarate has documented interactions with 3 drug classes — the most serious being alcohol (ethanol) (moderate), glucuronidated drugs (moderate) and kanamycin (minor) — and none of Moxidectin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Calcium D-glucarate Does Interact With Other Medications

Calcium D-glucarate has 125 moderate, 1 minor known drug interactions in our database — Moxidectin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 125 Minor 1 No known interaction 2,704 (incl. Moxidectin)
Taking anything else?

Check Another of Your Medications Against Calcium D-glucarate

Covers the 2,830 medications we’ve checked against Calcium D-glucarate. Pick one to open its full report.

What to actually watch for

What Moxidectin’s Own FDA Label Lists

This is not an interaction — none of it involves Calcium D-glucarate. These are the most notable effects listed in the ADVERSE REACTIONS section of Moxidectin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Low sodium Worth acting on
  • Hives Worth acting on
  • A low white blood cell count Worth acting on
  • A higher chance of infection Worth acting on
  • Chills
  • Blurred vision
  • Back pain
  • A fast or pounding heartbeat
  • Cough
  • Low blood pressure

Showing the 10 most notable of 20 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Moxidectin. Read the label on DailyMed › Calcium D-glucarate’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Calcium D-glucarate side to compare — that is a limit of the record, not a statement that Calcium D-glucarate has no side effects.

Everything else you take

See Every Supplement That Interacts With Moxidectin

This page covers Calcium D-glucarate only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Moxidectin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Moxidectin page

“Moxidectin is usually taken as a single oral dose to clear the parasite that causes river blindness, which means it only works if that one dose is fully absorbed. All 17 supplements flagged here can interfere with exactly that, and one of them, activated charcoal, is rated major because it binds drugs in the gut and can strip away a la…”

Reviewed by 2 · Jul 18, 2026

Open the Moxidectin interaction page

One more smart check

Taking Calcium D-glucarate as Part of a Dietary Supplement Product? Check It for Interactions

We hold 369 real supplement products containing Calcium D-glucarate, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Calcium D-glucarate. Even though Calcium D-glucarate itself has no known interaction with Moxidectin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Calcium D-glucarate and Moxidectin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Calcium D-glucarate
Top half

#422 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Moxidectin
Top half

#983 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Calcium D-glucarate reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Calcium D-glucarate and Moxidectin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Calcium D-glucarate

What is Calcium D-glucarate?

Calcium D-glucarate
  • Detoxification support
  • Hormone balance
  • Estrogen metabolism
  • Liver support
  • General wellness

Calcium D-glucarate is a supplement form of a natural compound found in fruits and vegetables that is promoted for 'detoxification' and helping the body clear excess hormones. Human evidence for these benefits is very limited, and most research comes from laboratory or animal studies. Talk to your pharmacist or doctor before using it, especially if you have a hormone-related condition.

Not applicable (a calcium salt of D-glucaric acid) · Tablets, capsules

An interaction check asks whether these two react with each other — it does not ask whether Calcium D-glucarate is a good idea for someone in your situation. Here is what our Calcium D-glucarate record says about it on its own.

Calcium D-glucarate: dosing

There is no official or standardized dose for calcium D-glucarate, and the best dose for any health goal has not been established in humans. Amounts used in supplements vary widely from product to product.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Calcium D-glucarate monograph — the full record covers uses, side effects and every documented interaction.

Read the full Calcium D-glucarate monograph & all interactions
Medication

About Moxidectin

What Is Moxidectin Used For?

Brand name: Moxidectin

Moxidectin Tablets are used to treat onchocerciasis — a parasitic infection caused by Onchocerca volvulus, commonly known as river blindness. It is approved for adults and children aged 4 years and older who weigh at least 13 kg (about 29 lbs).

Important to know: Moxidectin does not kill the adult O. volvulus worms — it targets the immature larvae (microfilariae) instead. Because of this, follow-up evaluation after treatment is advised. The safety and effectiveness of taking Moxidectin more than once for this infection has not been studied.

See full Moxidectin drug information
Keep checking

Other Drugs & Calcium D-glucarate

Browse every other medication we’ve checked against Calcium D-glucarate — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
125Moderate
1Minor
2,703No known interaction
125 Moderate 1 Minor 2,703 No interaction
Moderate

125 interactions

Showing 60 of 125 moderate interactions — see all 125 on the Calcium D-glucarate page.

Minor

1 interaction

No interaction 2,703 drugs checked — show the list

We also checked Calcium D-glucarate against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,703 medications checked with no known interaction — see the full Calcium D-glucarate list.

See the full Calcium D-glucarate interactions page
See every supplement checked against Moxidectin, ranked by severity
Evidence & sources

Calcium D-glucarate References

The 5 references that drive our Calcium D-glucarate monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Dwivedi C, Heck WJ, Downie AA, et al. Effect of calcium glucarate on B-glucuronidase activity and glucarate content on certain vegetables and fruits. Biochem Med Metab Bio 1990;43:83-92.
  2. Furuno K, Matsubara S, Ando K, Suzuki S. Preventive effect of D-glucarate against renal damage induced by kanamycin. J Antibiot (Tokyo) 1976;29:950-3. PubMed
  3. Mezey E. Increased urinary excretion of D-glucarate acid in alcoholism. Res Commun Chem Pathol Pharmacol 1976;15:735-42.
  4. Pantuck EJ, Pantuck CB, Anderson KE, et al. Effect of brussels sprouts and cabbage on drug conjugation. Clin Pharmacol Ther 1984;35:161-9. PubMed
  5. Anon. Calcium-D-Glucarate. Altern Med Review 2002;7(4):336-9.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Calcium D-glucarate and Moxidectin Together: Common Questions

Is it safe to take Calcium D-glucarate with Moxidectin?
We do not list a known interaction between Calcium D-glucarate and Moxidectin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Calcium D-glucarate and Moxidectin combination checked?
Interactions in our licensed database are recorded against drug classes. Moxidectin is filed under 1 classification, and Calcium D-glucarate has documented interactions with 3 drug classes — none of Moxidectin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Calcium D-glucarate interact with any other medications?
Yes. Calcium D-glucarate has 126 documented drug interactions in our database — Moxidectin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Moxidectin interact with any supplements?
Yes. Moxidectin has documented interactions with 17 supplements in our database — Calcium D-glucarate is not one of them. The Moxidectin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Calcium D-glucarate monograph Uses, safety profile, and every drug interaction in one place Moxidectin drug information The full plain-English guide to this medication Moxidectin supplement interactions Every supplement checked against Moxidectin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Moxidectin and Calcium D-glucarate?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.