Chicory - Denosumab Interaction
Herbal: Chicory
Also Known As: Cichorium intybus, Achicoria, Barbe de Capucin, Blue Sailors, Cheveux de Paysans, Chicorée, Cichorii Herba, Cichorii Radix, Common Chicory Root, Écoubette, Hendibeh, Herbe à Café, Hinduba, Kasani, Kasni, Racine de Chicorée Commune, Succory
Drug: Denosumab
Brand names:
Prolia, XGEVA
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 15, 2025
Interaction Details
There were no interactions found between Denosumab and Chicory. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Chicory Overview
Chicory root is the root of the chicory plant, which is native to Europe and Asia. It is a perennial plant that belongs to the daisy family and has blue, purple, or pink flowers that bloom in the summer. Chicory root is often used as a coffee substitute and in traditional medicine.
Chicory root is purported to have diuretic, laxative, and digestive properties and has been traditionally used to treat constipation, indigestion, and liver and gallbladder disorders. Chicory root is also thought to have antioxidant and anti-inflammatory effects and has been used to improve skin health and treat skin conditions such as acne and eczema.
Chicory root is a source of inulin (not to be confused with insulin), a type of soluble fiber that is used as a sweetener and to improve digestive health.
Denosumab Overview
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Denosumab injection (Prolia) is used
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to treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause (''change of life;'' end of menstrual periods) who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis.
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to treat men who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis.
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treat osteoporosis that is caused by corticosteroid medications in men and women who will be taking corticosteroid medications for at least 6 months and have an increased risk for fractures or who cannot take or did not respond to other medication treatments for osteoporosis.
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to treat bone loss in men who are being treated for prostate cancer with certain medications that cause bone loss,
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to treat bone loss in women with breast cancer who are receiving certain medications that increase their risk for fractures.
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Denosumab injection (Xgeva) is used
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to reduce the risk of fractures in people who have multiple myeloma (cancer that begins in the plasma cells and causes bone damage), and in people who have certain types of cancer that began in another part of the body but has spread to the bones.
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in adults and some adolescents to treat giant cell tumor of bone (GCTB; a type of bone tumor) that cannot be treated with surgery.
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to treat high calcium levels that are caused by cancer in people who did not respond to other medications.
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Chicory - More Interactions
Chicory interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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