Drug & supplement interaction

Galphimia Glauca + Cephalexin

Cephalexin brand names: Keflex, Keftab, Cephalex, Lexin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Galphimia Glauca and Cephalexin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Galphimia Glauca and Cephalexin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cephalexin and Galphimia Glauca in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Galphimia Glauca safety at a glance

Galphimia Glauca overall Use caution Short-term studies suggest it is generally well tolerated, but long-term safety data are limited.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cephalexin and Galphimia Glauca? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Cephalexin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Cephalexin is filed under 7 classifications — including organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates, antibiotic drugs. Galphimia Glauca has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Cephalexin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Galphimia Glauca Does Interact With Other Medications

Galphimia Glauca has 248 moderate known drug interactions in our database — Cephalexin isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Galphimia Glauca

Covers the 2,830 medications we’ve checked against Galphimia Glauca. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Galphimia Glauca and Cephalexin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Anxiety or restlessness Additional detail

    Galphimia Glauca

    “Orally, Galphimia glauca extract 7-14 mg daily has been associated with sedation and headache. Rarely, restlessness, nervousness, weakness, and other side effects have been reported; but it is unclear if Galphimia glauca was the causal factor.”

    Galphimia Glauca · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 99507. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78(14): PubMed

    Cephalexin

    Listed in the ADVERSE REACTIONS section of the FDA label for Cephalexin. Read the label on DailyMed ›

  • Headache Additional detail

    Galphimia Glauca

    “Orally, Galphimia glauca seems to be well tolerated.

    Most Common Adverse Effects:

    Orally: Epigastric burning, headache, nausea, sedation.”

    Galphimia Glauca · Natural Medicines adverse-effect record, reported in cluster headache.

    Cephalexin

    Listed in the ADVERSE REACTIONS section of the FDA label for Cephalexin. Read the label on DailyMed ›

  • Nausea Additional detail

    Galphimia Glauca

    “Orally, Galphimia glauca extract 7-14 mg daily has been associated with nausea and epigastric burning.”

    Galphimia Glauca · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 99507. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78(14): PubMed

    Cephalexin

    Listed in the ADVERSE REACTIONS section of the FDA label for Cephalexin. Read the label on DailyMed ›

Reported for Galphimia Glauca but not commonly for Cephalexin: drowsiness.

Effects for Cephalexin come from the ADVERSE REACTIONS section of its FDA label; effects for Galphimia Glauca come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Galphimia Glauca or Cephalexin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Galphimia Glauca or Cephalexin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Cephalexin

This page covers Galphimia Glauca only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cephalexin page lists 61 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 47 moderate · 11 minor.

From our pharmacist’s overview on the Cephalexin page

“Cephalexin (Keflex) is one of the most commonly prescribed oral antibiotics, usually for skin and urinary infections, and its supplement list warrants genuine care rather than a quick skim. Three of the 61 ingredients on file rate major.”

Reviewed by 2 · Jul 18, 2026

Open the Cephalexin interaction page

How much people look this up

Where Galphimia Glauca and Cephalexin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Galphimia Glauca
Steady interest

#1,333 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cephalexin
Top 5%

#65 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Galphimia Glauca reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Galphimia Glauca and Cephalexin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Galphimia Glauca

What is Galphimia Glauca?

Galphimia Glauca
  • Anxiety and stress
  • Insomnia
  • Allergic rhinitis and hay fever
  • Respiratory complaints
  • Traditionally used as an anticonvulsant

Galphimia glauca is a shrub from Mexico and Central America that has been studied mainly for anxiety, with some small clinical trials suggesting possible benefit. Overall the evidence is still limited and its long-term safety is not well established, so talk with your pharmacist or doctor before using it.

Galphimia glauca · Malpighiaceae · Leaves and aerial parts · Capsules, standardized extracts, tinctures, homeopathic preparations, tea

An interaction check asks whether these two react with each other — it does not ask whether Galphimia Glauca is a good idea for someone in your situation. Here is what our Galphimia Glauca record says about it on its own.

Galphimia Glauca: dosing

There is no well-established standard dose of Galphimia glauca. Clinical studies have used standardized extracts, but products on the market vary widely in their strength and how they are made.Because of this, follow the directions on the product label and do not exceed the recommended amount.

From our Galphimia Glauca monograph — the full record covers uses, side effects and every documented interaction.

Read the full Galphimia Glauca monograph & all interactions
Medication

About Cephalexin

What Is Cephalexin Used For?

Brand names: Keflex, Keftab, Cephalex, Lexin

Cephalexin treats bacterial infections caused by susceptible strains of bacteria. It is used for respiratory tract infections, ear infections (otitis media), skin and skin structure infections, bone infections, and genitourinary tract infections — including acute prostatitis.

It works only against bacterial infections — not viruses like colds or flu. Your prescriber should use it only when a bacterial infection is confirmed or strongly suspected, to help prevent antibiotic resistance.

Most-Reported Side Effects for Cephalexin

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Chronic kidney disease 2,157 reports
Renal failure 1,558 reports
Acute kidney injury 1,550 reports
Diarrhea 1,405 reports
Fatigue 1,303 reports
See full Cephalexin drug information
Keep checking

Other Drugs & Galphimia Glauca

Browse every other medication we’ve checked against Galphimia Glauca — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Galphimia Glauca page.

No interaction 2,581 drugs checked — show the list
Evidence & sources

Galphimia Glauca References

The 2 references that drive our Galphimia Glauca monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Herrera-Arellano, A., Jimenez-Ferrer, E., Zamilpa, A., et al. Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder. A randomized, double-blind clinical trial controlled with lorazepam. Planta Med
  2. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78(14): PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Galphimia Glauca and Cephalexin Together: Common Questions

Is it safe to take Galphimia Glauca with Cephalexin?
We do not list a known interaction between Galphimia Glauca and Cephalexin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Galphimia Glauca and Cephalexin have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Galphimia Glauca and Cephalexin combination checked?
Interactions in our licensed database are recorded against drug classes. Cephalexin is filed under 7 classifications, and Galphimia Glauca has documented interactions with 1 drug class — none of Cephalexin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Galphimia Glauca interact with any other medications?
Yes. Galphimia Glauca has 248 documented drug interactions in our database — Cephalexin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Cephalexin interact with any supplements?
Yes. Cephalexin has documented interactions with 61 supplements in our database — Galphimia Glauca is not one of them. The Cephalexin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cephalexin and Galphimia Glauca?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.