Drug & supplement interaction

Ip-6 + Loncastuximab Tesirine-Lpyl

Loncastuximab Tesirine-Lpyl brand name: Zynlontab.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Ip-6 and Loncastuximab Tesirine-Lpyl in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Ip-6 and Loncastuximab Tesirine-Lpyl

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Loncastuximab Tesirine-Lpyl and Ip-6 in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ip-6 safety at a glance

Ip-6 overall Use caution Generally considered low-risk in food amounts, but supplement safety is not well studied and it can reduce absorption of minerals.

Pregnancy Likely Safe When consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of IP-6 when used in amounts greater tha... Read the full pregnancy detail

Breastfeeding Likely Safe When consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of IP-6 when used in amounts greater tha... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Loncastuximab Tesirine-Lpyl and Ip-6? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Loncastuximab Tesirine-Lpyl

Interactions in our licensed database are recorded against drug classes, not just single drug names. Loncastuximab Tesirine-Lpyl is filed under a single classification — p-glycoprotein substrates. Ip-6 has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (moderate) — and none of Loncastuximab Tesirine-Lpyl’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Ip-6 Does Interact With Other Medications

Ip-6 has 122 moderate known drug interactions in our database — Loncastuximab Tesirine-Lpyl isn’t one of them. If you take anything else, check it against the full list below.

Moderate 122 No known interaction 2,708 (incl. Loncastuximab Tesirine-Lpyl)

Taking anything else?

Check Another of Your Medications Against Ip-6

Covers the 2,830 medications we’ve checked against Ip-6. Pick one to open its full report.

Special populations

Ip-6 in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of IP-6 when used in amounts greater than those found in foods; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Loncastuximab Tesirine-Lpyl

This page covers Ip-6 only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Loncastuximab Tesirine-Lpyl page lists 37 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: St. John's Wort (major), Bitter Melon (moderate), Black Pepper (moderate), Bulbine Natalensis (moderate) and Cannabis (moderate).

By severity: 1 major · 28 moderate · 8 minor.

From our pharmacist’s overview on the Loncastuximab Tesirine-Lpyl page

“Loncastuximab tesirine (Zynlonta) is an infusion treatment for lymphoma that has come back or stopped responding, so I treat anything that can shift its levels as a real safety question. All 37 ingredients on file interact through the same doorway, a transporter called P-glycoprotein that moves drugs across cell membranes.”

Reviewed by 2 · Jul 18, 2026

Open the Loncastuximab Tesirine-Lpyl interaction page

One more smart check

Taking Ip-6 as Part of a Dietary Supplement Product? Check It for Interactions

We hold 189 real supplement products containing Ip-6, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ip-6. Even though Ip-6 itself has no known interaction with Loncastuximab Tesirine-Lpyl, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Ip-6 and Loncastuximab Tesirine-Lpyl Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ip-6

Top 25%

#311 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Loncastuximab Tesirine-Lpyl

Steady interest

#2,787 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ip-6 reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Ip-6 and Loncastuximab Tesirine-Lpyl records this page draws on were last updated June 22, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Ip-6

What is Ip-6?

Antioxidant support
Cancer prevention interest
Kidney stone prevention
Heart and immune support
Reducing excess iron

IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supplement, often paired with inositol. It is most studied as an antioxidant and mineral binder, but human evidence for its popular uses—such as cancer prevention—is limited and not conclusive. Talk to your pharmacist or doctor before using it, especially if you have low mineral levels or a chronic condition.

Naturally found in whole grains, legumes, nuts, and seeds; supplements are usually made from rice bran or corn · Capsules, tablets, powders (often combined with inositol)

An interaction check asks whether these two react with each other — it does not ask whether Ip-6 is a good idea for someone in your situation. Here is what our Ip-6 record says about it on its own.

Ip-6: dosing

There is no officially established or standardized dose for IP-6 supplements. Products vary widely, and many combine IP-6 with inositol.The best approach is to follow the directions on the product label and not exceed them.

From our Ip-6 monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ip-6 monograph & all interactions

Medication

About Loncastuximab Tesirine-lpyl Injection

What Is Loncastuximab Tesirine-lpyl Injection Used For?

Brand name: Zynlontab

Loncastuximab tesirine-lpyl injection is used to treat a certain type of non-Hodgkin's lymphoma (NHL; a type of cancer that begins in a type of white blood cells that normally fights infection) that did not respond to or has returned after treatment with at least two other cancer treatments. Loncastuximab tesirine-lpyl is in a class of medications called antibody-drug conjugates. It works by killing cancer cells.

See full Loncastuximab Tesirine-lpyl Injection drug information

Keep checking

Other Drugs & Ip-6

Browse every other medication we’ve checked against Ip-6 — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

122Moderate

0Minor

2,707No known interaction

122 Moderate 2,707 No interaction

Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Ip-6 page.

No interaction 2,707 drugs checked — show the list

We also checked Ip-6 against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,707 medications checked with no known interaction — see the full Ip-6 list.

See the full Ip-6 interactions page

See every supplement checked against Loncastuximab Tesirine-Lpyl, ranked by severity

Evidence & sources

Ip-6 References

The 3 references that drive our Ip-6 monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc 1996;96:1027-39. PubMed
Vucenik I, Podczasy JJ, Shamsuddin AM. Antiplatelet activity of inositol hexaphosphate. Anticancer Res 1999;19:3689-93.
Ikenaga T, Kakumoto K, Kohda N, Yamamoto T. Effect of Inositol Hexaphosphate (IP6) on Serum Uric Acid in Hyperuricemic Subjects: a Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Plant Foods Hum Nutr. 2019 Sep;74(3):316-321. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ip-6 and Loncastuximab Tesirine-Lpyl Together: Common Questions

Is it safe to take Ip-6 with Loncastuximab Tesirine-Lpyl?

We do not list a known interaction between Ip-6 and Loncastuximab Tesirine-Lpyl. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Ip-6 and Loncastuximab Tesirine-Lpyl combination checked?

Interactions in our licensed database are recorded against drug classes. Loncastuximab Tesirine-Lpyl is filed under 1 classification, and Ip-6 has documented interactions with 1 drug class — none of Loncastuximab Tesirine-Lpyl's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Ip-6 interact with any other medications?

Yes. Ip-6 has 122 documented drug interactions in our database — Loncastuximab Tesirine-Lpyl is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Loncastuximab Tesirine-Lpyl interact with any supplements?

Yes. Loncastuximab Tesirine-Lpyl has documented interactions with 37 supplements in our database — Ip-6 is not one of them. The Loncastuximab Tesirine-Lpyl interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Ip-6 monograph Uses, safety profile, and every drug interaction in one place Loncastuximab Tesirine-lpyl Injection drug information The full plain-English guide to this medication Loncastuximab Tesirine-Lpyl supplement interactions Every supplement checked against Loncastuximab Tesirine-Lpyl, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Loncastuximab Tesirine-Lpyl and Ip-6?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.