Drug & supplement interaction

Juniper + Bivalirudin

Bivalirudin brand names: Angiomax, Angiox, Angiomax Rtu.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Juniper and Bivalirudin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Juniper and Bivalirudin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Bivalirudin and Juniper in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Juniper safety at a glance

Juniper overall Use caution Generally tolerated in food amounts, but medicinal doses may irritate the kidneys and should not be used long-term.
Pregnancy Unsafe When used orally. Juniper can increase uterine tone, interfere with fertility and implantation, and cause abortion. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Bivalirudin and Juniper? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Bivalirudin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Bivalirudin is filed under a single classification — anticoagulant/antiplatelet drugs. Juniper has documented interactions with 3 drug classes — the most serious being antidiabetes drugs (moderate), diuretic drugs (minor) and lithium (minor) — and none of Bivalirudin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Juniper Does Interact With Other Medications

Juniper has 86 moderate, 76 minor known drug interactions in our database — Bivalirudin isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Juniper

Covers the 2,830 medications we’ve checked against Juniper. Pick one to open its full report.

What to actually watch for

What Juniper Itself Has Been Linked To

This is not an interaction — nothing below involves Bivalirudin. It is the side-effect record for Juniper on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Juniper, this list is the first place to look.

  • Swelling Additional detail

    “Topically, juniper can cause skin irritation. Signs of topical poisoning include burning, erythema, inflammation with blisters, and edema (4). Repeated exposure to the juniper pollen can cause occupational allergies that affect the skin (6). In a case report, a 62-year-old woman developed burn-like blistering lesions after carrying juniper in close contact to her skin.”

    Juniper · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    3 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
    3. 103756. Tammaro A, Adebanjo GAR, Chello C, et al. Bullous dermatitis caused by common juniper. Contact Dermatitis. 2020. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Juniper — expand a row for the licensed statement it rests on. We haven’t matched Bivalirudin to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Bivalirudin.

Special populations

Juniper in Pregnancy & Breastfeeding

Pregnancy Unsafe

When used orally. Juniper can increase uterine tone, interfere with fertility and implantation, and cause abortion.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Bivalirudin

This page covers Juniper only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bivalirudin page lists 202 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Danshen (major), Piracetam (major), Aconite (moderate), Allspice (moderate) and Aloe (moderate).

By severity: 2 major · 183 moderate · 17 minor.

From our pharmacist’s overview on the Bivalirudin page

“Bivalirudin (Angiomax) is a strong intravenous blood thinner used during heart procedures like angioplasty, and because bleeding is already its main built-in danger, this list deserves genuine care. All 202 supplements on it interact the same basic way: they thin the blood or blunt platelets themselves, stacking bleeding risk on top of…”

Reviewed by 2 · Jul 18, 2026

Open the Bivalirudin interaction page

One more smart check

Taking Juniper as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,100 real supplement products containing Juniper, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Juniper. Even though Juniper itself has no known interaction with Bivalirudin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Juniper and Bivalirudin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Juniper
Top 25%

#161 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Bivalirudin
Top half

#1,106 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Juniper reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Juniper and Bivalirudin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Juniper

What is Juniper?

  • Water retention (diuretic)
  • Digestive upset and bloating
  • Urinary tract support
  • Joint and muscle discomfort
  • Flavoring (gin and food)

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its health benefits is limited, and it can irritate the kidneys with high doses or long-term use. Pregnant people and those with kidney problems should avoid it, and everyone should check with a pharmacist or doctor first.

Juniperus communis · Cupressaceae · Berries (ripe cones) and essential oil · Tea, capsules, tincture, essential oil, dried berries

An interaction check asks whether these two react with each other — it does not ask whether Juniper is a good idea for someone in your situation. Here is what our Juniper record says about it on its own.

Juniper: dosing

There is no well-established standard dose for juniper, and the right amount depends on the form (tea, capsule, tincture, or oil). Because of the risk of kidney irritation, experts generally advise against high doses or use longer than a few weeks.If you choose to use a juniper product, follow the directions on the label and do not exceed the recommended amount. Never take juniper essential oil by mouth without professional guidance.

From our Juniper monograph — the full record covers uses, side effects and every documented interaction.

Read the full Juniper monograph & all interactions
Medication

About Bivalirudin

Most-Reported Side Effects for Bivalirudin

From FAERS, the FDA’s public side-effect reporting system (960 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hemorrhage 87 reports
Heparin-induced thrombocytopenia 74 reports
Gastrointestinal haemorrhage 43 reports
Vascular stent thrombosis 39 reports
Thrombosis 38 reports
Keep checking

Other Drugs & Juniper

Browse every other medication we’ve checked against Juniper — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
76Minor
2,667No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Juniper page.

Minor

76 interactions

Showing 60 of 76 minor interactions — see all 76 on the Juniper page.

No interaction 2,667 drugs checked — show the list
Evidence & sources

Juniper References

The 7 references that drive our Juniper monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  5. Sanchez de Medina F, Gamez MJ, Jimenez I, et al. Hypoglycemic activity of juniper "berries." Planta Med 1994;60:197-200. PubMed
  6. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  7. Tammaro A, Adebanjo GAR, Chello C, et al. Bullous dermatitis caused by common juniper. Contact Dermatitis. 2020. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Juniper and Bivalirudin Together: Common Questions

Is it safe to take Juniper with Bivalirudin?
We do not list a known interaction between Juniper and Bivalirudin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Juniper and Bivalirudin combination checked?
Interactions in our licensed database are recorded against drug classes. Bivalirudin is filed under 1 classification, and Juniper has documented interactions with 3 drug classes — none of Bivalirudin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Juniper interact with any other medications?
Yes. Juniper has 162 documented drug interactions in our database — Bivalirudin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Bivalirudin interact with any supplements?
Yes. Bivalirudin has documented interactions with 202 supplements in our database — Juniper is not one of them. The Bivalirudin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Bivalirudin and Juniper?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.