Drug & supplement interaction

Raspberry Ketone + Dexchlorpheniramine

Dexchlorpheniramine brand names: Polaramine, Polaramine Repetabs.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Raspberry Ketone and Dexchlorpheniramine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Raspberry Ketone and Dexchlorpheniramine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dexchlorpheniramine and Raspberry Ketone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Raspberry Ketone safety at a glance

Raspberry Ketone overall Use caution Used in foods safely, but human safety data for high supplement doses is very limited.
Pregnancy Avoid Not enough safety information; avoid concentrated supplements during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid supplement use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dexchlorpheniramine and Raspberry Ketone? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Dexchlorpheniramine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Dexchlorpheniramine is filed under 8 classifications — including cytochrome p450 2d6 (cyp2d6) inhibitors, serotonergic drugs, serotonergic drugs. Raspberry Ketone has documented interactions with 2 drug classes — the most serious being stimulant drugs (moderate) and warfarin (coumadin) (moderate) — and none of Dexchlorpheniramine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Raspberry Ketone Does Interact With Other Medications

Raspberry Ketone has 174 moderate known drug interactions in our database — Dexchlorpheniramine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 174 No known interaction 2,656 (incl. Dexchlorpheniramine)
Taking anything else?

Check Another of Your Medications Against Raspberry Ketone

Covers the 2,830 medications we’ve checked against Raspberry Ketone. Pick one to open its full report.

What to actually watch for

What Raspberry Ketone Itself Has Been Linked To

This is not an interaction — nothing below involves Dexchlorpheniramine. It is the side-effect record for Raspberry Ketone on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Raspberry Ketone, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An irregular heartbeat / Raised blood pressure Worth acting on Additional detail

    “Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Although not well studied in humans, stimulant-related side effects are possible. Orally, cases of heart palpitations, tachycardia, elevated blood pressure, coronary vasospasm are reported after taking raspberry ketone.”

    Raspberry Ketone · Natural Medicines adverse-effect record, reported in arrhythmia.

    3 sources cited
    1. 17961. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
    2. 112386. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
    3. 112400. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.
  • Tremor or shakiness / Sweating / Diarrhea Additional detail

    “Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Although not well studied in humans, stimulant-related side effects are possible. Two case reports describe symptoms of sweating, diarrhea, and feelings of shakiness after oral use of raspberry ketone.”

    Raspberry Ketone · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 17961. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
    2. 112400. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.
  • A fast or pounding heartbeat Additional detail

    Recorded for Raspberry Ketone in the same Natural Medicines adverse-effect record shown under An irregular heartbeat / Raised blood pressure above.

Everything above comes from the Natural Medicines adverse-effect record for Raspberry Ketone — expand a row for the licensed statement it rests on. We haven’t matched Dexchlorpheniramine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Dexchlorpheniramine.

From our Q&A

Questions About Raspberry Ketone or Dexchlorpheniramine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Raspberry Ketone or Dexchlorpheniramine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Dexchlorpheniramine

This page covers Raspberry Ketone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dexchlorpheniramine page lists 198 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Henbane (major), Lithium (major) and Scopolia (major).

By severity: 6 major · 149 moderate · 43 minor.

From our pharmacist’s overview on the Dexchlorpheniramine page

“An allergy antihistamine like dexchlorpheniramine (Polaramine) sounds mild, but its interaction list warrants genuine care, and six of the 198 entries carry a major rating. The biggest cluster, 121 ingredients, can raise or lower the drug's blood levels through the liver enzyme that breaks it down.”

Reviewed by 2 · Jul 18, 2026

Open the Dexchlorpheniramine interaction page

One more smart check

Taking Raspberry Ketone as Part of a Dietary Supplement Product? Check It for Interactions

We hold 682 real supplement products containing Raspberry Ketone, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Raspberry Ketone. Even though Raspberry Ketone itself has no known interaction with Dexchlorpheniramine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Raspberry Ketone and Dexchlorpheniramine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Raspberry Ketone
Top 25%

#237 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dexchlorpheniramine
Top half

#1,228 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Raspberry Ketone reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Raspberry Ketone and Dexchlorpheniramine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Raspberry Ketone

What is Raspberry Ketone?

Raspberry Ketone
  • Weight loss
  • Fat burning
  • Boosting metabolism
  • Appetite support
  • General 'fat-burner' supplement

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most claims come from lab and animal studies using doses far higher than what you could get from food or typical supplements. If you choose to try it, talk to your pharmacist or doctor first.

Fruit-derived aromatic compound (4-(4-hydroxyphenyl)butan-2-one) · Capsules, tablets, softgels, powders, often combined with other weight-loss ingredients

An interaction check asks whether these two react with each other — it does not ask whether Raspberry Ketone is a good idea for someone in your situation. Here is what our Raspberry Ketone record says about it on its own.

Raspberry Ketone: dosing

There is no established or proven effective dose of raspberry ketone for weight loss or any other use. The amounts found in supplements vary widely from product to product.If you decide to try it, follow the directions on the product label and do not take more than recommended. Because supplements are not tightly regulated, the actual amount in a product may differ from what is listed, and quality can vary between brands.Before starting, it is a good idea to review the full ingredient list with your pharmacist, especially since many products contain caffeine or other added stimulants.

From our Raspberry Ketone monograph — the full record covers uses, side effects and every documented interaction.

Read the full Raspberry Ketone monograph & all interactions
Medication

About Chlorpheniramine

What Is Chlorpheniramine Used For?

Brand names: Polaramine, Polaramine Repetabs

Chlorpheniramine is used to temporarily relieve common allergy symptoms caused by hay fever (allergic rhinitis) or other upper respiratory allergies. These include runny nose, sneezing, itchy or watery eyes, and itching of the nose or throat.

These uses are supported across multiple products — including tablets (such as Aller-chlor, Allergy, Allergy Relief, Allergy Time, Anti Allergy, and Chlorpheniramine Maleate), extended-release tablets (Allergy Relief and Chlorphen-12), the oral solution Ed Chlorped Jr, and the inhalers ClorRelief and ClorRelief KIDs.

See full Chlorpheniramine drug information
Keep checking

Other Drugs & Raspberry Ketone

Browse every other medication we’ve checked against Raspberry Ketone — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
174Moderate
0Minor
2,655No known interaction
174 Moderate 2,655 No interaction
Moderate

174 interactions

Showing 60 of 174 moderate interactions — see all 174 on the Raspberry Ketone page.

No interaction 2,655 drugs checked — show the list

We also checked Raspberry Ketone against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,655 medications checked with no known interaction — see the full Raspberry Ketone list.

See the full Raspberry Ketone interactions page
See every supplement checked against Dexchlorpheniramine, ranked by severity
Evidence & sources

Raspberry Ketone References

The 4 references that drive our Raspberry Ketone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
  2. Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
  3. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
  4. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Raspberry Ketone and Dexchlorpheniramine Together: Common Questions

Is it safe to take Raspberry Ketone with Dexchlorpheniramine?
We do not list a known interaction between Raspberry Ketone and Dexchlorpheniramine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Raspberry Ketone and Dexchlorpheniramine combination checked?
Interactions in our licensed database are recorded against drug classes. Dexchlorpheniramine is filed under 8 classifications, and Raspberry Ketone has documented interactions with 2 drug classes — none of Dexchlorpheniramine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Raspberry Ketone interact with any other medications?
Yes. Raspberry Ketone has 174 documented drug interactions in our database — Dexchlorpheniramine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Dexchlorpheniramine interact with any supplements?
Yes. Dexchlorpheniramine has documented interactions with 198 supplements in our database — Raspberry Ketone is not one of them. The Dexchlorpheniramine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Raspberry Ketone monograph Uses, safety profile, and every drug interaction in one place Chlorpheniramine drug information The full plain-English guide to this medication Dexchlorpheniramine supplement interactions Every supplement checked against Dexchlorpheniramine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dexchlorpheniramine and Raspberry Ketone?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.