Medication interaction hub

What Supplements Interact with Benactyzine, Meprobamate?

Benactyzine, Meprobamate brand name: Deprol. Every interaction below applies to the brands too.

105 Interactions 7 Major 82 Moderate 16 Minor
Curated & coded by · Clinical Pharmacist · Updated September 15, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Benactyzine, Meprobamate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Benactyzine, Meprobamate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Meprobamate does the heavy sedating in Deprol (benactyzine is its partner), and that is why 78 of the 105 supplements and herbs on this list demand real caution. They pile extra sedation on top of the drug's own, and most of the seven major-rated interactions sit in that group. Beer and wine are the best documented, deepening drowsiness and other side effects, with kava and GHB products at the same serious end.

The rest splits two ways. Seventeen ingredients, activated charcoal chief among them, can keep an oral dose from absorbing, so space those well apart from the tablet. Another twelve, mostly cabbage and Brussels sprouts eaten regularly, may speed the liver pathway that clears certain drugs and lower their levels; those top out at moderate. All told 82 entries rate moderate and 16 minor, and none of those worry me the way the sedation group does.

— , Clinical Pharmacist · July 18, 2026

Major 7 Moderate 82 Minor 16 No known interaction 1,347

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Benactyzine, Meprobamate: Top Interactions at a Glance

The most significant Benactyzine, Meprobamate supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 105 interacting ingredients — plus 1,347 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Benactyzine, Meprobamate + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Beer + Benactyzine, Meprobamatei

Concomitant use may increase sedative and other adverse effects.

Read the full interaction Major Likelihood Likely Wine + Benactyzine, Meprobamatei

Concomitant use may increase sedative and other adverse effects.

Read the full interaction Major Likelihood Probable 1,4-butanediol + Benactyzine, Meprobamatei

Theoretically, concomitant use of 1,4-butanediol with CNS depressants may potentiate respiratory and CNS depression.

Read the full interaction Major Likelihood Probable Activated Charcoal + Benactyzine, Meprobamatei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Gamma-hydroxybutyrate (ghb) + Benactyzine, Meprobamatei

GHB may increase the risk of serious CNS and respiratory depression.

Read the full interaction Major Likelihood Probable Kava + Benactyzine, Meprobamatei

Combining kava with CNS depressants can have additive sedative effects.

Read the full interaction
The complete list

Every Supplement Checked Against Benactyzine, Meprobamate

All 1,452 ingredients in our database, ranked by severity — 105 with a Benactyzine, Meprobamate interaction on file and 1,347 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Benactyzine, Meprobamate?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Baikal Skullcap with Benactyzine, Meprobamate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative propert...

Full Baikal Skullcap + Benactyzine, Meprobamate answer

Can you take Calendula with Benactyzine, Meprobamate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.

Full Calendula + Benactyzine, Meprobamate answer

Can you take Chrysin with Benactyzine, Meprobamate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.

Full Chrysin + Benactyzine, Meprobamate answer

Can you take Gamma-aminobutyric Acid (gaba) with Benactyzine, Meprobamate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.

Full Gamma-aminobutyric Acid (gaba) + Benactyzine, Meprobamate answer

Can you take Theanine with Benactyzine, Meprobamate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.

Full Theanine + Benactyzine, Meprobamate answer

Can you take Beer with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase sedative and other adverse effects.

Full Beer + Benactyzine, Meprobamate answer

Can you take Wine with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase sedative and other adverse effects.

Full Wine + Benactyzine, Meprobamate answer

Can you take 1,4-butanediol with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use of 1,4-butanediol with CNS depressants may potentiate respiratory and CNS depression.

Full 1,4-butanediol + Benactyzine, Meprobamate answer

Can you take Activated Charcoal with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the rout...

Full Activated Charcoal + Benactyzine, Meprobamate answer

Can you take Gamma-hydroxybutyrate (ghb) with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. GHB may increase the risk of serious CNS and respiratory depression.

Full Gamma-hydroxybutyrate (ghb) + Benactyzine, Meprobamate answer

Can you take Kava with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Combining kava with CNS depressants can have additive sedative effects.

Full Kava + Benactyzine, Meprobamate answer

Can you take L-tryptophan with Benactyzine, Meprobamate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use of L-tryptophan with CNS depressants might cause additive sedative effects.

Full L-tryptophan + Benactyzine, Meprobamate answer

Can you take Brussels Sprout with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. A cabbage and Brussels sprout-containing diet seems to boost elimination through glucuronide conjugation.

Full Brussels Sprout + Benactyzine, Meprobamate answer

Can you take Cabbage with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.

Full Cabbage + Benactyzine, Meprobamate answer

Can you take Coffee Charcoal with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...

Full Coffee Charcoal + Benactyzine, Meprobamate answer

Can you take European Mandrake with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Benactyzine, Meprobamate answer

Can you take Glucomannan with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.

Full Glucomannan + Benactyzine, Meprobamate answer

Can you take Yerba Mansa with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might cause additive or prolonged sedative effects.

Full Yerba Mansa + Benactyzine, Meprobamate answer

Can you take 5-htp with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.

Full 5-htp + Benactyzine, Meprobamate answer

Can you take Adrue with Benactyzine, Meprobamate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold comp...

Full Adrue + Benactyzine, Meprobamate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Benactyzine, Meprobamate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Benactyzine, Meprobamate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Benactyzine, Meprobamate sits in 3 interaction categories. Open any one to see what the group means:

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Benactyzine, Meprobamate through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Benactyzine, Meprobamate through this category.

Glucuronidated Drugs 12 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

12 of the supplement ingredients on this page reach Benactyzine, Meprobamate through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Benactyzine, Meprobamate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Benactyzine, Meprobamate.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Benactyzine, Meprobamate & Supplements: Common Questions

What supplements interact with Benactyzine, Meprobamate?
In our interaction database, 105 supplement and herbal ingredients have an interaction with Benactyzine, Meprobamate on file — 7 rated major, 82 moderate, and 16 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Beer, Wine, 1,4-butanediol.
Which Benactyzine, Meprobamate supplement interactions are the most serious?
Focus on the major group: Beer, Wine, 1,4-butanediol, Activated Charcoal and Gamma-hydroxybutyrate (ghb), among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Benactyzine, Meprobamate?
That depends entirely on which supplement. The honest answer for Benactyzine, Meprobamate is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Deprol have the same supplement interactions as Benactyzine, Meprobamate?
Yes — Deprol all contain Benactyzine, Meprobamate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Benactyzine, Meprobamate and my other medications?
This page covers Benactyzine, Meprobamate against supplements and herbal ingredients. Checking Benactyzine, Meprobamate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.