Medication interaction hub

What Supplements Interact with Budesonide?

Budesonide brand names: Entocort EC, Pulmicort, Uceris, Tarpeyo, Eohilia. Every interaction below applies to the brands too.

154 Interactions 4 Major 110 Moderate 40 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Budesonide? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Budesonide against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Budesonide (Entocort EC, Pulmicort, Uceris) is a steroid designed to act locally in the gut or airways while the liver enzyme CYP3A4 clears most of what reaches the bloodstream. That design is exactly why this page warrants real care. Most of the list is ingredients that either block that enzyme, letting steroid levels climb until side effects follow, or rev it up and weaken the drug. Grapefruit is the clearest example of the first kind, St. John's wort of the second, and both sit among the majors.

A smaller cluster piles onto budesonide's own steroid effects, mostly through potassium loss, which is how lily-of-the-valley earns its major rating. A third group simply interferes with absorbing the oral forms, so space those products well apart from your dose. Four of the 154 entries rate major, alongside 110 moderate and 40 minor, but grapefruit is the one most people actually keep in the fridge.

— , Clinical Pharmacist · July 18, 2026

Major 4 Moderate 110 Minor 40 No known interaction 1,298

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Budesonide: Top Interactions at a Glance

The Budesonide supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 154 interacting ingredients — plus 1,298 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Budesonide Combinations Today

The Budesonide + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Unlikely Green Tea + Budesonidei

Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.

Read the full interaction Moderate Likelihood Possible Lime + Budesonidei

Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.

Read the full interaction Minor Likelihood Unlikely Mommy's Bliss Gripe Water + Budesonidei

Mommy's Bliss Gripe Water contains fennel seed.

Read the full interaction Moderate Likelihood Possible German Chamomile + Budesonidei

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.

Read the full interaction Moderate Likelihood Possible Cannabis + Budesonidei

Theoretically, cannabis may increase the levels and adverse effects of CYP3A4 substrates.

Read the full interaction Moderate Likelihood Possible Goldenseal + Budesonidei

Goldenseal might increase serum levels of drugs metabolized by CYP3A4.

Read the full interaction
The complete list

Every Supplement Checked Against Budesonide

All 1,452 ingredients in our database, ranked by severity — 154 with a Budesonide interaction on file and 1,298 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Budesonide?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Green Tea with Budesonide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.

Full Green Tea + Budesonide answer

Can you take Lime with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.

Full Lime + Budesonide answer

Can you take Mommy's Bliss Gripe Water with Budesonide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Mommy's Bliss Gripe Water contains fennel seed.

Full Mommy's Bliss Gripe Water + Budesonide answer

Can you take German Chamomile with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.

Full German Chamomile + Budesonide answer

Can you take Cannabis with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cannabis may increase the levels and adverse effects of CYP3A4 substrates.

Full Cannabis + Budesonide answer

Can you take Resveratrol with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.

Full Resveratrol + Budesonide answer

Can you take Rhubarb with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, frequent and high doses of rhubarb might increase the risk of hypokalemia when taken with corticosteroids.

Full Rhubarb + Budesonide answer

Can you take Rooibos with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.

Full Rooibos + Budesonide answer

Can you take Sage with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Sage + Budesonide answer

Can you take Schizonepeta with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, induces cytochrome P450 (CYP) 3A4.

Full Schizonepeta + Budesonide answer

Can you take Slippery Elm with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Budesonide answer

Can you take Sodium with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.

Full Sodium + Budesonide answer

Can you take Sodium Bicarbonate with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sodium bicarbonate may increase the risk of hypokalemia in patients taking corticosteroids.

Full Sodium Bicarbonate + Budesonide answer

Can you take Squill with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Squill contains cardiac glycosides.

Full Squill + Budesonide answer

Can you take Star Of Bethlehem with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Full Star Of Bethlehem + Budesonide answer

Can you take Strophanthus with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Use of corticosteroids may cause electrolyte depletion and increase the risk of strophanthus toxicity.

Full Strophanthus + Budesonide answer

Can you take Sulforaphane with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.

Full Sulforaphane + Budesonide answer

Can you take Swamp Milkweed with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking swamp milkweed with prolonged corticosteroid therapy might increase the risk of toxicity.

Full Swamp Milkweed + Budesonide answer

Can you take Sweet Annie with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.

Full Sweet Annie + Budesonide answer

Can you take Syrian Rue with Budesonide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Syrian Rue + Budesonide answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Budesonide is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Budesonide, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Budesonide sits in 4 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Budesonide through this category.

Corticosteroids 18 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

18 of the supplement ingredients on this page reach Budesonide through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Budesonide through this category.

Budesonide (Entocort, Uceris) 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Budesonide through this category.

About Budesonide

Budesonide is a corticosteroid used to treat Crohn's disease and reduce protein in urine from kidney disease.

Generic name: Budesonide  ·  Brand names: Entocort EC, Pulmicort, Uceris, Tarpeyo, Eohilia.

See the full Budesonide drug information

Related: does Budesonide deplete any nutrients?

Budesonide has 24 reported nutrient associations in the research literature — see the Budesonide nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Budesonide

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Budesonide.

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Pharmacist Counseling Corner

Budesonide & Supplements: Common Questions

What supplements interact with Budesonide?
In our interaction database, 154 supplement and herbal ingredients have an interaction with Budesonide on file — 4 rated major, 110 moderate, and 40 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Grapefruit, Activated Charcoal, Lily-of-the-valley.
Which Budesonide supplement interactions are the most serious?
The 4 major-rated combinations — led by Grapefruit, Activated Charcoal, Lily-of-the-valley and St. John's Wort — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Budesonide?
That depends entirely on which supplement. The honest answer for Budesonide is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Entocort EC have the same supplement interactions as Budesonide?
Yes — Entocort EC, Pulmicort, Uceris, Tarpeyo, Eohilia all contain Budesonide, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Budesonide deplete any vitamins or nutrients?
It might — Budesonide has 24 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Budesonide nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Budesonide and my other medications?
This page covers Budesonide against supplements and herbal ingredients. Checking Budesonide against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Budesonide drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.