Medication interaction hub

What Supplements Interact with Emapalumab-Lzsg?

Emapalumab-Lzsg brand name: Gamifant. Every interaction below applies to the brands too.

53 Interactions 52 Moderate 1 Minor
Curated & coded by · Clinical Pharmacist · Updated October 1, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Emapalumab-Lzsg? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Emapalumab-Lzsg against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Emapalumab-lzsg (Gamifant) quiets an immune system that has turned dangerously overactive in a rare condition called hemophagocytic lymphohistiocytosis. All 53 supplement interactions on file share a single theme, a possible boost to immune activity that could work against the drug. Not one rates major; 52 are moderate and one minor, so this reads as a watch list, not a warning siren. Echinacea is the everyday example, an immune booster people take at the first sniffle that points the wrong way here.

Most of this evidence comes from lab and animal research rather than documented harm in patients, so the concern is theoretical. Still, when a medicine's whole purpose is dialing immunity down, anything sold to rev it up deserves a word with your pharmacist before you add it. Ginseng and the medicinal mushrooms follow the same logic as echinacea: less suppression could give the underlying disease room to flare again.

— , Clinical Pharmacist · July 18, 2026

Moderate 52 Minor 1 No known interaction 1,399

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Emapalumab-Lzsg: Top Interactions at a Glance

The most significant Emapalumab-Lzsg supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 53 interacting ingredients — plus 1,399 more checked with no known interaction. See the complete ranked list.

Start here

The Moderate Interactions to Know About

The most clinically significant Emapalumab-Lzsg + supplement combinations in our database, best-documented first. Open any card for the full report.

Moderate Likelihood Possible Active Hexose Correlated Compound (ahcc) + Emapalumab-Lzsgi

Theoretically, taking AHCC might decrease the effects of immunosuppressant drugs.

Read the full interaction Moderate Likelihood Possible Alfalfa + Emapalumab-Lzsgi

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Read the full interaction Moderate Likelihood Possible American Ginseng + Emapalumab-Lzsgi

Theoretically, American ginseng use might interfere with immunosuppressive therapy.

Read the full interaction Moderate Likelihood Possible Andrographis + Emapalumab-Lzsgi

Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.

Read the full interaction Moderate Likelihood Possible Ashwagandha + Emapalumab-Lzsgi

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.

Read the full interaction Moderate Likelihood Possible Astragalus + Emapalumab-Lzsgi

Theoretically, astragalus might interfere with immunosuppressive therapy.

Read the full interaction
The complete list

Every Supplement Checked Against Emapalumab-Lzsg

All 1,452 ingredients in our database, ranked by severity — 53 with a Emapalumab-Lzsg interaction on file and 1,399 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Emapalumab-Lzsg?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Alfalfa with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Full Alfalfa + Emapalumab-Lzsg answer

Can you take American Ginseng with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, American ginseng use might interfere with immunosuppressive therapy.

Full American Ginseng + Emapalumab-Lzsg answer

Can you take Andrographis with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.

Full Andrographis + Emapalumab-Lzsg answer

Can you take Ashwagandha with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.

Full Ashwagandha + Emapalumab-Lzsg answer

Can you take Astragalus with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, astragalus might interfere with immunosuppressive therapy.

Full Astragalus + Emapalumab-Lzsg answer

Can you take Bee Venom with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bee venom might stimulate immune system activity.Theoretically, bee venom might interfere with immunosuppressant therapy.

Full Bee Venom + Emapalumab-Lzsg answer

Can you take Beta-glucans with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, beta-glucans might interfere with immunosuppressive therapy.

Full Beta-glucans + Emapalumab-Lzsg answer

Can you take Black Hoof Mushroom with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black hoof mushroom might reduce the effects of immunosuppressant medications.

Full Black Hoof Mushroom + Emapalumab-Lzsg answer

Can you take Black Seed with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black seed might interfere with immunosuppressive therapy.

Full Black Seed + Emapalumab-Lzsg answer

Can you take Blood Irradiation Therapy with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research suggests that blood irradiation therapy may stimulate immune function in some patients.

Full Blood Irradiation Therapy + Emapalumab-Lzsg answer

Can you take Blue-green Algae with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.

Full Blue-green Algae + Emapalumab-Lzsg answer

Can you take Boswellia Serrata with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.

Full Boswellia Serrata + Emapalumab-Lzsg answer

Can you take Bupleurum with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, bupleurum might decrease the effects of immunosuppressants.

Full Bupleurum + Emapalumab-Lzsg answer

Can you take Cat's Claw with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cat's claw might interfere with immunosuppressive therapy.

Full Cat's Claw + Emapalumab-Lzsg answer

Can you take Catechu with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, catechu might interfere with immunosuppressant therapy.

Full Catechu + Emapalumab-Lzsg answer

Can you take Ceylon Leadwort with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Plumbagin, a constituent of Ceylon leadwort, has demonstrated immunosuppressant activity in animal research.

Full Ceylon Leadwort + Emapalumab-Lzsg answer

Can you take Chaga with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chaga might interfere with immunosuppressive therapy.

Full Chaga + Emapalumab-Lzsg answer

Can you take Cordyceps with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.

Full Cordyceps + Emapalumab-Lzsg answer

Can you take Echinacea with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.

Full Echinacea + Emapalumab-Lzsg answer

Can you take Elderberry with Emapalumab-Lzsg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.

Full Elderberry + Emapalumab-Lzsg answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Emapalumab-Lzsg is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Emapalumab-Lzsg, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Emapalumab-Lzsg sits in 1 interaction category. Open any one to see what the group means:

Immunosuppressants 53 ingredients

Medications that damp down the immune system. Supplements that stimulate immunity can work against them.

53 of the supplement ingredients on this page reach Emapalumab-Lzsg through this category.

About Emapalumab-Lzsg

Emapalumab-lzsg injection (Gamifant) is an interferon gamma-blocking antibody used to treat primary hemophagocytic lymphohistiocytosis (HLH) and HLH/macrophage activation syndrome in Still's disease when standard treatments have not worked.

Generic name: Emapalumab-Lzsg  ·  Brand name: Gamifant.

See the full Emapalumab-lzsg Injection drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Emapalumab-Lzsg

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Emapalumab-Lzsg.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Emapalumab-Lzsg & Supplements: Common Questions

What supplements interact with Emapalumab-Lzsg?
In our interaction database, 53 supplement and herbal ingredients have an interaction with Emapalumab-Lzsg on file — 0 rated major, 52 moderate, and 1 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Active Hexose Correlated Compound (ahcc), Alfalfa, American Ginseng.
Which Emapalumab-Lzsg supplement interactions are the most serious?
None of the Emapalumab-Lzsg supplement interactions on file are currently rated major. The most significant are the 52 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Emapalumab-Lzsg?
That depends entirely on which supplement. The honest answer for Emapalumab-Lzsg is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Gamifant have the same supplement interactions as Emapalumab-Lzsg?
Yes — Gamifant all contain Emapalumab-Lzsg, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Emapalumab-Lzsg and my other medications?
This page covers Emapalumab-Lzsg against supplements and herbal ingredients. Checking Emapalumab-Lzsg against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Emapalumab-lzsg Injection drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of October 1, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.