Medication interaction hub

What Supplements Interact with Eravacycline?

Eravacycline brand name: Xerava. Every interaction below applies to the brands too.

145 Interactions 3 Major 109 Moderate 33 Minor
Curated & coded by · Clinical Pharmacist · Updated September 29, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Eravacycline? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Eravacycline against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

145 supplements and herbal ingredients have interactions with Eravacycline on file in the HelloPharmacist interaction database — 3 rated major, 109 moderate, and 33 minor. The most serious involve Grapefruit, Oleander and St. John's Wort.

Our assessment: with 3 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Eravacycline.

Major 3 Moderate 109 Minor 33 No known interaction 1,307

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Eravacycline: Top Interactions at a Glance

The Eravacycline supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 145 interacting ingredients — plus 1,307 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Eravacycline Combinations Today

The Eravacycline + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Possible Bromelain + Eravacyclinei

Theoretically, bromelain might increase levels of tetracycline antibiotics.

Read the full interaction Moderate Likelihood Probable Manganese + Eravacyclinei

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.

Read the full interaction Minor Likelihood Unlikely Eleuthero + Eravacyclinei

Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.

Read the full interaction Moderate Likelihood Possible Feverfew + Eravacyclinei

Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.

Read the full interaction Moderate Likelihood Possible Quercetin + Eravacyclinei

Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.

Read the full interaction Major Likelihood Likely Grapefruit + Eravacyclinei

Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Read the full interaction
The complete list

Every Supplement Checked Against Eravacycline

All 1,452 ingredients in our database, ranked by severity — 145 with a Eravacycline interaction on file and 1,307 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Eravacycline?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Bromelain with Eravacycline?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, bromelain might increase levels of tetracycline antibiotics.

Full Bromelain + Eravacycline answer

Can you take Manganese with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, manganese might reduce the absorption of tetracycline antibiotics.

Full Manganese + Eravacycline answer

Can you take Eleuthero with Eravacycline?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.

Full Eleuthero + Eravacycline answer

Can you take Feverfew with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.

Full Feverfew + Eravacycline answer

Can you take Quercetin with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.

Full Quercetin + Eravacycline answer

Can you take Dolomite with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, the calcium and magnesium in dolomite might decrease the absorption of tetracycline antibiotics.

Full Dolomite + Eravacycline answer

Can you take Guggul with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guggul might reduce the effects of CYP3A4 substrates.

Full Guggul + Eravacycline answer

Can you take Iron with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Iron might decrease levels of tetracycline antibiotics by reducing their absorption.

Full Iron + Eravacycline answer

Can you take Magnesium with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Magnesium decreases absorption of tetracyclines.

Full Magnesium + Eravacycline answer

Can you take Schisandra with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Schisandra can increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Schisandra + Eravacycline answer

Can you take Strontium with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, strontium might decrease the absorption of tetracycline antibiotics.

Full Strontium + Eravacycline answer

Can you take Tree Turmeric with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tree turmeric might increase the levels and clinical effects of drugs that are substrates of CYP3A4.

Full Tree Turmeric + Eravacycline answer

Can you take Whey Protein with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, whey protein might decrease tetracycline absorption.

Full Whey Protein + Eravacycline answer

Can you take Yogurt with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking yogurt with tetracycline antibiotics seems to reduce the levels and clinical effects of tetracycline antibiotics.

Full Yogurt + Eravacycline answer

Can you take Zinc with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Zinc might reduce levels of tetracycline antibiotics.

Full Zinc + Eravacycline answer

Can you take Acacia Rigidula with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP3A4 su...

Full Acacia Rigidula + Eravacycline answer

Can you take Adrafinil with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, adrafanil might reduce levels and clinical effects of CYP3A4 substrates.

Full Adrafinil + Eravacycline answer

Can you take African Wild Potato with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro evidence shows that African wild potato extract can inhibit cytochrome P450 3A4 (CYP3A4) enzyme activity by up to 86%.

Full African Wild Potato + Eravacycline answer

Can you take American Elder with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking American elder might increase levels of CYP3A4 substrates.

Full American Elder + Eravacycline answer

Can you take Astaxanthin with Eravacycline?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.

Full Astaxanthin + Eravacycline answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Eravacycline is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Eravacycline, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Eravacycline sits in 2 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Eravacycline through this category.

Tetracycline Antibiotics 24 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

24 of the supplement ingredients on this page reach Eravacycline through this category.

About Eravacycline

Eravacycline is an intravenous antibiotic used to treat complicated intra-abdominal infections in adults.

Generic name: Eravacycline  ·  Brand name: Xerava.

See the full Eravacycline Injection drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Eravacycline

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Eravacycline.

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Pharmacist Counseling Corner

Eravacycline & Supplements: Common Questions

What supplements interact with Eravacycline?
In our interaction database, 145 supplement and herbal ingredients have an interaction with Eravacycline on file — 3 rated major, 109 moderate, and 33 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Grapefruit, Oleander, St. John's Wort.
Which Eravacycline supplement interactions are the most serious?
The 3 major-rated combinations — led by Grapefruit, Oleander and St. John's Wort — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Eravacycline?
That depends entirely on which supplement. The honest answer for Eravacycline is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Xerava have the same supplement interactions as Eravacycline?
Yes — Xerava all contain Eravacycline, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Eravacycline and my other medications?
This page covers Eravacycline against supplements and herbal ingredients. Checking Eravacycline against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Eravacycline Injection drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 29, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.