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Dietary supplement

100% Pure GABA 1000 mg Ingredients & Drug Interactions

by NutraBio

100% Pure GABA 1000 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 100% Pure GABA 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

100% Pure GABA 1000 mg is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against 100% Pure GABA 1000 mg by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Pure GABA 1000 mg by NutraBio — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of 100% Pure GABA 1000 mg by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: GABA (gamma-aminobutyric acid) at 1000 mg per capsule. GABA is a neurotransmitter — a chemical messenger in your brain and nervous system.

The capsule itself is made from vegetable material.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Gamma-aminobutyric Acid (gaba) product and its label doesn't state a use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for GABA isn't there yet. Our data rates it as having insufficient reliable evidence for anxiety, attention-deficit hyperactivity disorder (ADHD), athletic performance, cerebral palsy, and chronic bronchitis.

That doesn't mean it doesn't work — it means the studies so far haven't been solid enough to draw a real conclusion either way.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, GABA is generally well tolerated in the short term, though long-term safety hasn't been well studied. The most common side effects people report are drowsiness, upset stomach, minor throat burning, muscle weakness, and nausea.

One patient reported a temporary stop in menstrual periods when taking GABA with another supplement, though this is rare. We don't have enough safety information to recommend this product in pregnancy.

For breastfeeding, the safety data advises against it — talk with your doctor or pharmacist for personalized guidance on whether it's right for you.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood pressure medications (antihypertensives) and any sedating drugs you take — CNS depressants like sleep aids or anti-anxiety medication — before adding this product. Altogether, these interactions span 417 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

GABA might appeal to someone looking for a relaxation aid, but the evidence for what it actually does isn't established yet. If you take blood pressure medication or anything sedating, check with us first.

Talk to your pharmacist before you start, especially if you're pregnant, breastfeeding, or take any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 100% Pure GABA 1000 mg, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908232375
Net contents 500 Cap(s)
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50880
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 100% Pure GABA 1000 mg by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetable Capsule(s)
Maximum serving Sizes:
2 Vegetable Capsule(s)
Servings per container
250
UPC/BARCODE
649908232375
IngredientAmount% DV
GABA1000 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

2 capsules - Daily

Suggested Use: As a dietary supplement, take 2 capsules (1000 mg) daily or as directed by your physician.

Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breastfeeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

General Statements

Manufactured in a GMP & FDA Inspected Facility

Pharmaceutical Grade HPLC Lab Tested

Promotes Relaxation - Enhances Mental Focus - Supports Restful Sleep

1000 Milligrams

Vegetable capsule

Formulation

Zero Fillers or Excipients Inferior Ingredients Banned Substances / Added Sugars Proprietary Blends Hidden Ingredients

Allergen Free - Non-GMO - Gluten Free - BSE/TSE Free

No fillers - No excipients - No additives

Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free and BSE/TSE Free. No added sugars, salt, preservatives, salicylates, or arificial color, flavor or fragrance.

Vegetarian

Brand IP Statement(s)

Amino Therapy

NutraBio Since 1996

Formula

Gamma-Aminobutyric Acid

Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free and BSE/TSE Free.

Seals/Symbols

True Label Full Label Disclosure

Made In USA

FDA Statement of Identity

Dietary Supplement

Quality and purity since 1996. NutraBio manufactures on our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

+ These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

23237-005 B20114-002

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

100% Pure GABA 1000 mg by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

100% Pure GABA 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 100% Pure GABA 1000 mg by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container250 Amounts shown are per serving.

GABA

Interacts with
419 drugs
1000 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

GABA monograph & interactions

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

100% Pure GABA 1000 mg by NutraBio Drug Interactions

Want to check YOUR meds against 100% Pure GABA 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

GABA 419

Individual Drug Interactions

The ingredients in 100% Pure GABA 1000 mg interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in 100% Pure GABA 1000 mg interact with drugs. Each result below shows which ingredient is responsible. GABA

Each ingredient & the kinds of drugs it affects

For each ingredient in 100% Pure GABA 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

GABA2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
GABA full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 100% Pure GABA 1000 mg, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

100% Pure GABA 1000 mg by NutraBio: Common Questions

Does 100% Pure GABA 1000 mg by NutraBio interact with any medications?
Yes. Based on its ingredients, 100% Pure GABA 1000 mg has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
100% Pure GABA 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does GABA actually work for anxiety?
The evidence isn't clear yet. Our data rates it as having insufficient reliable evidence to say whether it helps with anxiety. You'd be trying it without solid proof it works.
What are the side effects?
Most commonly, drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea. It's generally well tolerated in the short term, but we don't know much about long-term safety.
Is it safe to take while pregnant?
We don't have enough safety information to say either way. Talk with your doctor or pharmacist before taking it in pregnancy — they can give you personalized advice.
Can I take this if I'm breastfeeding?
The safety data advises against it while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you.
Will this make me drowsy?
Drowsiness is the most commonly reported side effect. It may be worse if you're already taking other sedating medications like sleep aids or anti-anxiety drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 100% Pure GABA 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

100% Pure GABA 1000 mg label
Go deeper

The Full Monographs Behind 100% Pure GABA 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

100% Pure GABA 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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