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Dietary supplement

Beta Glucan 100 mg Ingredients & Drug Interactions

by Source Naturals

Beta Glucan 100 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta Glucan 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beta Glucan 100 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-1,3/1,6-Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beta Glucan 100 mg by Source Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Beta Glucan 100 mg by Source Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Beta Glucan 100 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beta-1,3/1,6-glucan, 100 mg per capsule. Beta-glucans are soluble fibers derived from yeast, mushrooms, or cereal grains — they're also found naturally in foods like oats and barley.

The capsule itself is filled with inactive ingredients: microcrystalline cellulose (a binder), gelatin, and silica (an anti-caking agent).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: maintain or stimulate immune effectiveness.
  • We looked for evidence on: Aging, Allergic rhinitis (hay fever), Atopic dermatitis (eczema), Benign prostatic hyperplasia (BPH), Cancer, Canker sores — and 4 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Cancer, Chronic fatigue syndrome (CFS), Atopic dermatitis (eczema), and more.

Beta-glucans are likely effective for two conditions: dyslipidemia (abnormal cholesterol and triglyceride levels) and coronary heart disease (CHD). The evidence supporting these uses comes from clinical research showing benefits in these areas.

If you're considering this supplement for heart health or cholesterol management, the research is promising — though you should always discuss it with your doctor as part of your overall treatment plan.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food are generally well tolerated by most people. Concentrated supplements like this one, however, haven't been studied as thoroughly, so caution is advised.

In clinical trials, oral beta-glucans were well-tolerated overall, though one child in a high-dose cancer trial developed temporary liver enzyme elevations shortly after starting the supplement. There isn't enough safety data on concentrated supplement doses during breastfeeding, so talk it over with your doctor or pharmacist if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take any blood pressure medications (antihypertensives) or immunosuppressants — beta-glucans may lower blood pressure and might interfere with drugs meant to suppress immunity. Both are Moderate-severity interactions.

Use the medication checker on this page to confirm your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you have high cholesterol or coronary heart disease and your doctor supports it, beta-glucans have research behind them. If you take blood pressure medication or immunosuppressants, you'll need to clear this with your own doctor or pharmacist first — the interaction risk is real.

Otherwise, most people tolerate it well, though safety data on supplements is thinner than it is for food sources.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Glucan 100 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078017592
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 26, 2020
DSLD ID 214339
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Glucan 100 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
021078017592
IngredientAmount% DV
Beta-1,3/1,6-Glucan100 mg--

Other ingredients: Microcrystalline Cellulose, Gelatin, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Purified Beta-1,3/1,6-Glucan

Beta-glucan is a complex polysaccharide composed of glucose molecules extracted and purified from the cell wall of common baker's yeast, Saccharomyces cerevisiae. Beta-glucan is used to maintain or stimulate the effectiveness of the immune system. Animal and human cell culture studies have shown that beta-glucan can stimulate several aspects of immune function, such as phagocytosis and interleukin production. Source Naturals Beta Glucan uses a purification process that removes the mannoproteins and yeast residues that may reduce the effectiveness of beta-glucan.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule daily before a meal.

Precautions

Caution: If you are pregnant, may become pregnant, breastfeeding, or if you are taking immunosuppressant drugs, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation

Contains no dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta Glucan 100 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta Glucan 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta Glucan 100 mg by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Beta-1,3/1,6-Glucan

Interacts with
293 drugs
100 mg per serving

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta-1,3/1,6-Glucan monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Gelatin, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Glucan 100 mg by Source Naturals Drug Interactions

Want to check YOUR meds against Beta Glucan 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta-1,3/1,6-Glucan 293

Individual Drug Interactions

The ingredients in Beta Glucan 100 mg interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beta Glucan 100 mg interact with drugs. Each result below shows which ingredient is responsible. Beta-1,3/1,6-Glucan

Each ingredient & the kinds of drugs it affects

For each ingredient in Beta Glucan 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-1,3/1,6-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta-1,3/1,6-Glucan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beta Glucan 100 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Beta Glucan 100 mg by Source Naturals: Common Questions

Does Beta Glucan 100 mg by Source Naturals interact with any medications?
Yes. Based on its ingredients, Beta Glucan 100 mg has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beta Glucan 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure medication?
Not without checking with your doctor first. Beta-glucans can lower blood pressure, so combining them with blood pressure drugs might push yours too low. Talk to your pharmacist or doctor about whether it's safe for you.
Will this help my cholesterol?
Beta-glucans are likely effective for dyslipidemia — that's abnormal cholesterol and triglyceride levels. That said, it's one tool among many; your doctor can help you figure out if it fits your plan.
Are there any common side effects?
Oral beta-glucans are generally well tolerated. In trials, they didn't cause significant side effects in most people, though one high-dose study in children reported a temporary liver enzyme change in one participant.
Is this safe to take while breastfeeding?
There isn't enough research on concentrated supplement doses during breastfeeding to say one way or another. Talk with your doctor or pharmacist about whether it's right for you.
What exactly is beta-glucan?
It's a type of soluble fiber found naturally in yeast, mushrooms, and grains like oats and barley. This supplement concentrates it in a 100 mg capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Glucan 100 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Glucan 100 mg label
Go deeper

The Full Monographs Behind Beta Glucan 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Beta Glucan 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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