Bifido Complex Ingredients & Drug Interactions
by Kirkman
What is this page for?
First and foremost: checking Bifido Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bifido Complex is a dietary supplement by Kirkman with 4 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bifido Complex by Kirkman
Ask about any prescription or over-the-counter medication and we check it for interactions with Bifido Complex by Kirkman — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bifido Complex by Kirkman
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Bifido Complex contains four live probiotic bacteria species: Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium breve, and Bifidobacterium animalis lactis. These are "friendly" bacteria meant to support your gut health.
The capsule itself is made from hypromellose (a plant-based coating), microcrystalline cellulose, silicon dioxide, and water—all inactive ingredients that help hold the product together.
Does it work?
Moderate evidence
The evidence for what these probiotics actually do is mixed. Bifidobacterium bifidum shows possibly effective evidence for irritable bowel syndrome (IBS) and respiratory tract infections.
Bifidobacterium breve, on the other hand, is rated possibly ineffective for age-related cognitive decline and sepsis. For the other conditions listed—hay fever, anxiety, asthma, antibiotic-associated diarrhea, Alzheimer's disease—we don't have enough reliable evidence to say whether these bacteria help or not.
Data for the other two ingredients isn't established in our records.
How safe is it?
Well-documented data
These bacteria are generally well tolerated in healthy people, but caution is warranted if you're seriously ill or have a weakened immune system—talk to your doctor first. Rare side effects from the checked ingredients include abdominal discomfort, bloating, flatulence, constipation, and a dry cough.
Very rarely, in critically ill or premature infants, Bifidobacterium species have caused serious bloodstream infections (bacteremia); this is extremely uncommon in otherwise healthy adults. For pregnancy and breastfeeding, Bifidobacterium longum is rated possibly safe for both, and Bifidobacterium bifidum is rated possibly safe during pregnancy—but data on breastfeeding for bifidum isn't on file.
Because safety data are limited overall, check with your doctor before use, especially if you're pregnant, breastfeeding, or seriously ill.
Meds to double-check
Moderate interaction found
Antibiotic drugs are the main one to watch. Because these are live bacteria, antibiotics will kill them and make this probiotic less effective.
Space your antibiotic doses at least a few hours away from this product—ask your pharmacist for a dosing schedule that works.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you have IBS or recurring respiratory infections and you're in good health, this probiotic blend is worth discussing with your pharmacist. Skip it if you're taking antibiotics right now—space them several hours apart instead.
If you're seriously ill, immune-compromised, pregnant, or breastfeeding, get your doctor's okay first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bifido Complex, straight from the product label.
| Brand | Kirkman |
|---|---|
| Barcode (UPC) | 812325021925 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 296951 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bifido Complex by Kirkman, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium longum | 0 NP | -- |
| Bifidobacterium bifidum | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Bifidobacterium breve | 0 NP | -- |
| Kirkman Proprietary Probiotic Blend | 75 mg | -- |
Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Important: Keep bottle refrigerated and tightly capped.
Do not remove the desiccant bag or oxygen absorber if present.
Precautions
Keep out of the reach of children.
Formulation
Free of: milk, eggs, fish, shellfish, tree nuts, peanuts, wheat or soy
Gluten-free
Seals/Symbols
Ultra tested
cGMP Good Manufacturing Products Consistent Quality
Formula
15 billion CFUs
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: One to two capsules daily or as directed by a physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bifido Complex by Kirkman label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bifido Complex by Kirkman
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Kirkman Proprietary Probiotic Blend
- › Bifidobacterium longum
- › Bifidobacterium bifidum
- › Bifidobacterium animalis lactis
- › Bifidobacterium breve
Other (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Bifido Complex by Kirkman Drug Interactions
HelloPharmacist Interaction Report
Bifido Complex by Kirkman contains four Bifidobacterium species, and the ones we could check do interact with one medication type: antibiotics.
All three checked ingredients—Bifidobacterium longum, Bifidobacterium bifidum, and Bifidobacterium breve—carry a Moderate interaction with antibiotic drugs. Since these are live organisms, antibiotics can kill them off and reduce their effectiveness.
The fix is simple: space out your doses. Take your antibiotic at a different time than this probiotic, ideally a few hours apart.
Read the full breakdown — every affected drug type, severity by severity
Additionally, we couldn't check Bifidobacterium animalis lactis—we hold no interaction data for that ingredient. Altogether, these interactions span 182 individual medications.
Use the medication checker below to look up your exact antibiotic before you start this product, and let your pharmacist know the timing so we can help you separate them properly.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bifido Complex?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bifido Complex interact with 182 drugs. Click any drug to see the details.
3 of the 4 ingredients in Bifido Complex interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium longum Bifidobacterium bifidum Bifidobacterium breve
CefotetanCefotan
How Cefotetan interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefotetan interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefotetan interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefotetan interactionCefoxitinMefoxin
How Cefoxitin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefoxitin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefoxitin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefoxitin interactionCefpodoxime ProxetilVantin
How Cefpodoxime Proxetil interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefpodoxime Proxetil interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefpodoxime Proxetil interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefpodoxime Proxetil interactionCefprozilCefzil
How Cefprozil interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefprozil interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefprozil interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefprozil interactionCeftazidimeCeftazidime, Ceptaz, Fortaz, Tazicef, Tazidime
How Ceftazidime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftazidime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftazidime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ceftazidime interactionCeftibutenCedax
How Ceftibuten interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftibuten interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftibuten interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ceftibuten interactionCeftizoximeCefizox
How Ceftizoxime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftizoxime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ceftizoxime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftizoxime interactionCeftolozane Sulfate, Tazobactam SodiumZerbaxa
How Ceftolozane Sulfate, Tazobactam Sodium interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftolozane Sulfate, Tazobactam Sodium interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftolozane Sulfate, Tazobactam Sodium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ceftolozane Sulfate, Tazobactam Sodium interactionCeftriaxoneRocephin
How Ceftriaxone interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ceftriaxone interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftriaxone interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftriaxone interactionCefuroximeCeftin, Kefurox, Zinacef
How Cefuroxime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefuroxime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefuroxime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefuroxime interactionCephalexinCephalex, Keflex, Keftab, Lexin
How Cephalexin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cephalexin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cephalexin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cephalexin interactionCephapirinCefadyl
How Cephapirin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cephapirin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cephapirin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cephapirin interactionCephradineAnspor, Velosef
How Cephradine interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cephradine interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cephradine interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cephradine interactionChloramphenicolChloromycetin, Chloromycetin Injection, Chloromycetin Ophthalmic
How Chloramphenicol interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Chloramphenicol interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Chloramphenicol interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Chloramphenicol interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Chlortetracycline interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Chlortetracycline interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Chlortetracycline interactionCinoxacinCinobac
How Cinoxacin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cinoxacin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cinoxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cinoxacin interactionCiprofloxacinCiloxan, Cipro, Cipro IV, Cipro XR, Ciprobay, Otiprio
How Ciprofloxacin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ciprofloxacin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ciprofloxacin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ciprofloxacin interactionClarithromycinBiaxin, Biaxin XL
How Clarithromycin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clarithromycin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Clarithromycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clarithromycin interactionClinafloxacinClinafloxacin
How Clinafloxacin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Clinafloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clinafloxacin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clinafloxacin interactionClindamycinCleocin, Cleocin T Gel, ClindaMax, Clindesse, Dalacin C
How Clindamycin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clindamycin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Clindamycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clindamycin interactionClofazimineLamprene
How Clofazimine interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clofazimine interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clofazimine interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Clofazimine interactionCloxacillin SodiumCloxapen, Cloxi, Tegopen
How Cloxacillin Sodium interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cloxacillin Sodium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cloxacillin Sodium interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cloxacillin Sodium interactionColistimethateColy-Mycin M
How Colistimethate interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Colistimethate interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Colistimethate interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Colistimethate interactionCyclacillinCyclapen-W, Cylcapen
How Cyclacillin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cyclacillin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cyclacillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cyclacillin interactionCycloserineSeromycin
How Cycloserine interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cycloserine interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cycloserine interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cycloserine interactionDalbavancin HydrochlorideDalvance
How Dalbavancin Hydrochloride interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Dalbavancin Hydrochloride interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Dalbavancin Hydrochloride interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Dalbavancin Hydrochloride interactionDapsoneAczone, Avlosulfon, Dapsone
How Dapsone interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Dapsone interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Dapsone interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Dapsone interactionDaptomycinCubicin, Dapzura RT
How Daptomycin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Daptomycin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Daptomycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Daptomycin interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Demeclocycline interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Demeclocycline interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Demeclocycline interactionDicloxacillin InjectionDynapen Injection
How Dicloxacillin Injection interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Dicloxacillin Injection interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Dicloxacillin Injection interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Dicloxacillin Injection interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bifido Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium longum
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Bifidobacterium bifidum
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
Bifidobacterium breve
Antibiotic Drugs
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.
Brand information
Manufacturer and brand details for Bifido Complex, from the product label.
Kirkman
See all Kirkman products- Name
- Kirkman
- City
- Lake Oswego
- State
- OR
- ZipCode
- 97035
- Phone Number
- 503.694.1600 1.800.245.8282
- Web Address
- kirkmangroup.com
Bifido Complex by Kirkman: Common Questions
Does Bifido Complex by Kirkman interact with any medications?
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Where does this information come from?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bifido Complex is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bifido Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographBifidobacterium Breve
Interacts with 182 drugsBifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...
Read the full Bifidobacterium Breve monograph →Sources & How We Checked
Bifido Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 37 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Bifidobacterium Breve 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
- Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
- Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
- Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed
See these in context on the Bifidobacterium Breve monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC