Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

BioActive Carbon Iodine Ingredients & Drug Interactions

by Microbe Formulas

Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

BioActive Carbon Iodine is a dietary supplement by Microbe Formulas with 5 active ingredients. Its ingredients are commonly taken for general wellness and energy, gut health, antioxidant support.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dibasic acid, Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of BioActive Carbon Iodine by Microbe Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (5 mg) without saying how much of each component you get.
  • “Total Iodide/Iodine” is listed as a grouped ingredient — the label gives one combined amount (12.50 mg) without saying how much of each component you get.

BioActive Carbon Iodine contains 5 ingredients, of which iodine is the main active one. Iodine is essential for thyroid function and healthy metabolism.

The product also contains fulvic acid compounds — listed as dibasic acid (fulvic acid), polyelectrolytes of fulvic acid, and polysaccharides — which are promoted for supporting the body's natural detoxification and nutrient absorption, though the evidence for these claims in humans is limited. There are no inactive fillers listed for this product.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Radiation exposure — rated "Likely Effective" (Iodine) (Natural Medicines).
  • On file: Iodine deficiency — rated "Likely Effective" (Iodine) (Natural Medicines).
  • On file: Fibrocystic breast disease — rated "Possibly Effective" (Iodine) (Natural Medicines).
  • On file: Oral mucositis — rated "Possibly Effective" (Iodine) (Natural Medicines).
  • On file: Periodontitis — rated "Possibly Effective" (Iodine) (Natural Medicines).

Iodine in this product is likely effective for preventing radiation exposure and treating iodine deficiency — both well-established roles. It's possibly effective for oral mucositis (mouth sores from cancer treatment) and periodontitis (gum disease), though the evidence is less robust.

The fulvic acid compounds have insufficient evidence to rate for respiratory tract infections, lead toxicity, eczema, fatigue, or hay fever. We simply don't have enough reliable human data to say whether they work for those uses.

The evidence, ingredient by ingredient Fulvic Acid Iodine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Iodine is well tolerated when you stay within safe dietary amounts, but high doses can trigger thyroid problems — including goiter (enlarged thyroid), overactive or underactive thyroid, and even thyroid nodules. You may also notice a metallic taste, nausea, diarrhea, headache, or runny nose.

Rarely, people can have a hypersensitivity reaction with swelling, rash, or bleeding. Taking large amounts over time can cause acnelike skin lesions called iododerma.

For pregnancy and nursing: iodine is likely safe and actually needed for your baby's development, but use only the amount your doctor advises and avoid high-dose products. The fulvic acid compounds lack enough safety data — the facts advise against them during pregnancy and while breastfeeding.

Short-term use of fulvic acid appears tolerated, with mild side effects like diarrhea, headache, or sore throat reported in trials, though a thorough safety review hasn't been done.

Side effects, ingredient by ingredient Fulvic Acid Iodine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Iodine, Fulvic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; lithium.
  • For scale: 264 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BioActive Carbon Iodine, double-check with your doctor or pharmacist if you take lithium, antithyroid medications, or amiodarone — all have moderate interactions with the iodine in this product that may alter how well your thyroid function is controlled. Also flag blood thinners and antiplatelet drugs (the fulvic acid may reduce their effect), immune-suppressing medicines (which this product may interfere with), or thyroid hormone replacement (the fulvic acid may disrupt your levels).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is mainly useful if you're iodine-deficient or need protection against radiation exposure. The fulvic acid compounds have unproven benefits and limited safety data.

If you take lithium, antithyroid drugs, amiodarone, blood thinners, medicines that suppress immunity, or thyroid hormone replacement, talk with your doctor or pharmacist before starting — the interactions here are real enough to need review.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioActive Carbon Iodine, straight from the product label.

Brand Microbe Formulas
Barcode (UPC) 788000132401
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 242124
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioActive Carbon Iodine by Microbe Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
788000132401
IngredientAmount% DV
Iodine5 mg--
Proprietary Blend5 mg--
Dibasic acid0 NP--
Polyelectrolytes of Fulvic Acid0 NP--
Polysaccharides0 NP--
Total Iodide/Iodine12.5 mg8333%
Iodide7.5 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 1 tablet daily with food or as otherwise directed by a healthcare practitioner.

Precautions

Warning: Please consult your healthcare practitioner before use if you are pregnant, breastfeeding, or considering use for a child.

Warning: Please consult your healthcare practitioner before use if you are pregnant, breastfeeding, or considering use for a child.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Statement of Identity

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Dietary Supplement

Formulation

Non GMO Gluten free No fillers

100% Vegan

See for yourself

BioActive Carbon Iodine by Microbe Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BioActive Carbon Iodine by Microbe Formulas

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

5 mg per serving

Total Iodide/Iodine

12.5 mg per serving
Interaction report

BioActive Carbon Iodine by Microbe Formulas Drug Interactions

Want to check YOUR meds against BioActive Carbon Iodine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
264Drugs
264 Moderate

Ingredients driving the most interactions

Iodine 7

Each ingredient & the kinds of drugs it affects

For each ingredient in BioActive Carbon Iodine with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dibasic acid3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D

Iodine3 drug types · 7 drugs

Amiodarone (Cordarone)

Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Probable Evidence D
Lithium

Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for BioActive Carbon Iodine, from the product label.

Microbe Formulas

See all Microbe Formulas products
Name
Microbe Formulas
Street Address
3750 E. Pewter Falls St., Suite 100
City
Meridian
State
ID
ZipCode
83642
Web Address
MicrobeFormulas.com
Pharmacist Counseling Corner

BioActive Carbon Iodine by Microbe Formulas: Common Questions

Does BioActive Carbon Iodine by Microbe Formulas interact with any medications?
Yes. Based on its ingredients, BioActive Carbon Iodine has a known interaction with 264 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BioActive Carbon Iodine contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is iodine safe if I'm pregnant or nursing?
Iodine itself is likely safe during pregnancy and nursing — your baby actually needs it for development. But use only the amount your doctor tells you to take and avoid high-dose products. The fulvic acid compounds in this product, though, don't have enough safety data; the guidance says to avoid them while pregnant or breastfeeding.
What are the most common side effects I might feel?
With iodine, you might notice a metallic taste, nausea, diarrhea, headache, or a runny nose. The fulvic acid compounds can cause diarrhea, headache, or sore throat. These are usually mild, but if you're taking large amounts over weeks or months, watch for acnelike skin bumps, especially on your face and upper back.
Will this help my iodine deficiency?
Yes — iodine is likely effective for treating iodine deficiency. That's one of the main reasons to take it. Your doctor can check your iodine levels to confirm you need it and decide on the right dose.
What's fulvic acid doing in here?
Fulvic acid is added for its claimed role in detoxification and nutrient absorption, but we don't have enough solid human evidence to say it actually works for those things. Short-term use appears tolerated, though the long-term safety picture isn't clear.
Can I take this if I'm on thyroid medicine?
You'll need to check with your doctor first. Both the iodine and the fulvic acid can interfere with how thyroid medicine works — iodine can alter your thyroid function directly, and fulvic acid may disrupt your hormone levels. Your doctor may need to monitor your thyroid or adjust your dose.
What if I'm taking a blood thinner?
The fulvic acid in this product may reduce how well your blood thinner works by speeding up clot formation. Talk to your pharmacist or doctor before starting — you may need blood-work monitoring or a dose adjustment.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioActive Carbon Iodine is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioActive Carbon Iodine label
Sources

Sources & How We Checked

BioActive Carbon Iodine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Iodine 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  3. Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
  4. Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
  7. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  8. Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
  9. Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
  10. Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
  11. Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
  12. Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
  13. Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
  14. Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
  15. Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
  16. Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
  17. Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
  18. Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
  19. Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
  20. Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
  21. Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
  22. Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
  23. Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
  24. Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
  25. Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
  26. Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed

See these in context on the Iodine monograph →

Fulvic Acid 3 references
  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

See these in context on the Fulvic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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