Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

CBD Oil 6% Ingredients & Drug Interactions

by SuperSmart

Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

CBD Oil 6% is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are non psychotropic Hemp Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of CBD Oil 6% by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Cannabidiol” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

This product has one active ingredient: cannabidiol (CBD), the non-intoxicating compound from hemp. It's formulated as a 6% CBD oil in softgel capsules.

The only other ingredient listed is olive oil, which serves as a carrier and filler.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have evidence in our data that CBD or hemp oil is effective for constipation, eczema (atopic dermatitis), or familial hypercholesterolemia. The evidence we hold for these uses is rated insufficient — meaning it hasn't been established well enough to make a reliable claim.

If you're considering this product for a specific health concern, talk with your pharmacist or doctor about what the current research actually supports.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods in normal dietary amounts are generally well tolerated. However, concentrated supplements and extracts like this one are less studied for safety.

Serious side effects are rare, but case reports include allergic reactions (hives, facial swelling, shortness of breath, and anaphylaxis in people with hemp seed allergy), heart rhythm problems (long QT syndrome and syncope), and in one young child given very high doses of hemp extract, elevated liver enzymes and hepatitis. Allergy to hemp seed is uncommon but can occur even on first exposure.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take estrogens (hormone therapy — Moderate severity), antihypertensive or ACE inhibitor blood pressure drugs, anticoagulants or antiplatelet agents (blood thinners), or drugs processed by your liver through the CYP1A2 or CYP3A4 pathways. Altogether, these interactions span 927 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on estrogen therapy, blood pressure medication, blood thinners, or drugs metabolized through your liver's CYP1A2 or CYP3A4 pathways, check this product against your medications before starting. If you have a known hemp or cannabis seed allergy, avoid it.

For everyone else, talk with your pharmacist about whether this product is right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CBD Oil 6%, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003827610
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 250678
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CBD Oil 6% by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
15
UPC/BARCODE
5453003827610
IngredientAmount% DV
Cannabidiol10 mg--
non psychotropic Hemp Oil156.25 mg--

Other ingredients: Olive Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Full spectrum

This supplement contains no psychotropic substance.

FDA Statement of Identity

Dietary Supplement

Formula

10 mg per day

Each softgel contains 78,125 mg hemp oil standardised to 6.4% cannabidiol (CBD) ie 5 mg of CBD.

Suggested/Recommended/Usage/Directions

Recommended Use: Adults. Take 2 softgels a day.

Precautions

Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.

Keep out of childrens' reach.

As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.

Storage

Store away from direct light, heat and humidity.

See for yourself

CBD Oil 6% by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in CBD Oil 6% by SuperSmart

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container15 Amounts shown are per serving.

Cannabidiol

10 mg per serving

Other (inactive) ingredients: Olive Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

CBD Oil 6% by SuperSmart Drug Interactions

Want to check YOUR meds against CBD Oil 6%?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in CBD Oil 6% with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

non psychotropic Hemp Oil6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for CBD Oil 6%, from the product label.

SuperSmart

See all SuperSmart products
Name
SN Worldwide Unipessoal, Lda
Street Address
Avenida Do Infante 66, Edificio Quinta Avenida 1 C
City
Funchal
ZipCode
9000-015
Pharmacist Counseling Corner

CBD Oil 6% by SuperSmart: Common Questions

Does CBD Oil 6% by SuperSmart interact with any medications?
Yes. Based on its ingredients, CBD Oil 6% has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CBD Oil 6% contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm allergic to hemp seed?
No. While hemp seed allergy is uncommon, it can cause serious reactions including hives, facial swelling, shortness of breath, and anaphylaxis. Talk to your pharmacist or doctor before using any hemp product if you've had any allergic reaction to hemp or cannabis seed.
What side effects might I notice?
In normal doses, hemp products are generally well tolerated. Serious side effects are rare but include allergic reactions and heart rhythm problems. If you experience any unusual symptoms, especially shortness of breath, heart palpitations, or swelling, stop and contact your doctor or pharmacist right away.
Is it safe to take during pregnancy or breastfeeding?
We don't have safety data on file for hemp oil or CBD during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice before using this product if you're pregnant or nursing.
Does this actually work for what I want to take it for?
Our data don't show reliable evidence that CBD or hemp oil is effective for constipation, eczema, or high cholesterol. If you're considering it for one of these or another condition, ask your pharmacist what research actually supports its use.
Why does the data say 'concentrated extracts are less studied'?
Hemp seed eaten as food — like in protein bars or ground into dishes — has been consumed safely for years. But this product is a concentrated supplement, and there's simply less long-term research on high-dose supplements. That's why caution is advised until we know more.
Should I be worried about the 927 medications listed?
That number reflects all individual drugs that theoretically interact with hemp oil's effects on hormones, blood pressure, blood clotting, and liver metabolism. Most of those interactions are Minor severity. Check your specific medications on this page to see if any apply to you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CBD Oil 6% is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CBD Oil 6% label
Sources

Sources & How We Checked

CBD Oil 6%'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring