CBN Tablets 1000 mg THC-Free Ingredients & Drug Interactions
by FluxxLab
What is this page for?
First and foremost: checking CBN Tablets 1000 mg THC-Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CBN Tablets 1000 mg THC-Free is a dietary supplement by FluxxLab with 3 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phytocannabinoid-Rich Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CBN Tablets 1000 mg THC-Free by FluxxLab
Ask about any prescription or over-the-counter medication and we check it for interactions with CBN Tablets 1000 mg THC-Free by FluxxLab — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CBN Tablets 1000 mg THC-Free by FluxxLab
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This product contains 3 active ingredients: Total Cannabinoids, Cannabinol, and Phytocannabinoid-Rich Hemp extract, each contributing to the 1000 mg total per tablet. The hemp extract is the ingredient we have the most data on; the other two are cannabinoid compounds.
The tablet also contains several inactive ingredients—calcium hydroxyphosphate, magnesium stearate, microcrystalline cellulose, dicalcium phosphate, and silicon dioxide—which are standard binders and fillers used to form and stabilize the tablet.
Does it work?
Couldn't assess
The evidence on these ingredients isn't established in our data. The hemp extract has been studied for constipation, atopic dermatitis (eczema), and familial hypercholesterolemia (a genetic cholesterol condition), but in each case the research is insufficient to reliably rate whether it works.
We don't hold effectiveness ratings for the other two active ingredients.
How safe is it?
Well-documented data
Hemp seed products in food amounts are generally well tolerated. Concentrated extracts and supplements like this one are much less studied, so caution is advised.
Serious adverse effects are rare but have been reported: occasional cases of allergic reactions (hives, facial swelling, shortness of breath, and in rare instances anaphylaxis) and very rare reports of heart rhythm problems. One case of elevated liver enzymes and hepatitis occurred in a young child given very high doses of hemp extract for seizures—the dose was far larger than what's in this tablet.
Pregnancy and lactation safety information is not on file for these ingredients. If you're pregnant or nursing, talk with your pharmacist or doctor before taking this product.
Meds to double-check
Moderate interaction found
Check these medication types with your pharmacist before taking this product: estrogen therapy (Moderate concern), blood pressure medications (antihypertensive drugs and ACE inhibitors), blood thinners and antiplatelet drugs, and any drugs that rely on liver enzymes CYP1A2 or CYP3A4 for how your body clears them.
The bottom line
Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may interest you if you're exploring cannabinoids and want a THC-free option. However, if you take blood pressure medications, blood thinners, estrogen therapy, or drugs processed through your liver's CYP1A2 or CYP3A4 pathways, check your exact medications with the tool on this page first.
Talk to your pharmacist—they can tell you whether it's safe for your specific situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CBN Tablets 1000 mg THC-Free, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CBN Tablets 1000 mg THC-Free by FluxxLab, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Cannabinoids | 1000 mg | -- |
| Cannabinol | 33.3 mg | -- |
| Phytocannabinoid-Rich Hemp extract | 0 NP | -- |
Other ingredients: Calcium Hydroxyphosphate, Magnesium Stearate, Microcrystalline Cellulose, Dicalcium Phosphate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use Take 1-2 tablets orally. Adjust dosage as needed. Individual results may vary.
Precautions
Warning: Consult with your healthcare provider before using if you are nursing, pregnant or taking medication.
If adverse reactions occur, discontinue and consult with your physician.
Keep out of reach of children.
Storage
Store in a cool, dark location.
Formula
Lab tested less 0.3% THC CBN Tablets with terpenes 33 mg each
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CBN Tablets 1000 mg THC-Free by FluxxLab label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CBN Tablets 1000 mg THC-Free by FluxxLab
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Total Cannabinoids
Cannabinol
Phytocannabinoid-Rich Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Phytocannabinoid-Rich Hemp extract monograph & interactionsOther (inactive) ingredients: Calcium Hydroxyphosphate, Magnesium Stearate, Microcrystalline Cellulose, Dicalcium Phosphate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
CBN Tablets 1000 mg THC-Free by FluxxLab Drug Interactions
HelloPharmacist Interaction Report
FluxxLab's CBN Tablets 1000 mg THC-Free do interact with medications—specifically through the phytocannabinoid-rich hemp extract, one of the three active ingredients.
The most serious concern is with estrogens (hormone therapy), rated Moderate: theoretically, hemp may interfere with how your body handles estrogen, though the exact mechanism isn't fully understood.
Read the full breakdown — every affected drug type, severity by severity
Minor interactions are documented with several drug types. Blood pressure medications (antihypertensive drugs and ACE inhibitors) could theoretically have additive effects and lower your blood pressure further.
Blood thinners and antiplatelet drugs (like aspirin or warfarin) carry a theoretical bleeding risk, though human data doesn't yet confirm this happens in practice. Two enzyme systems in your liver—CYP1A2 and CYP3A4—may be induced by hemp, which could reduce the effectiveness of drugs that depend on those pathways.
We were not able to check two of the three ingredients: Total Cannabinoids and Cannabinol. Neither has interaction data on file.
Altogether, these interactions span 927 individual medications.
Use the medication checker below to search your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CBN Tablets 1000 mg THC-Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CBN Tablets 1000 mg THC-Free interact with 938 drugs. Click any drug to see the details.
1 of the 3 ingredients in CBN Tablets 1000 mg THC-Free interact with drugs. Each result below shows which ingredient is responsible. Phytocannabinoid-Rich Hemp extract
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with CBN Tablets 1000 mg THC-Free — through 1 ingredient. Tap an ingredient for the detail:
Phytocannabinoid-rich Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Phytocannabinoid-rich Hemp Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CBN Tablets 1000 mg THC-Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Phytocannabinoid-Rich Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for CBN Tablets 1000 mg THC-Free, from the product label.
FluxxLab
See all FluxxLab products- Name
- FluxxLab
- City
- Montrose
- State
- CO
- ZipCode
- 81401
- Web Address
- FluxxLab.com
CBN Tablets 1000 mg THC-Free by FluxxLab: Common Questions
Does CBN Tablets 1000 mg THC-Free by FluxxLab interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this with my blood pressure medication?
Is this safe during pregnancy or breastfeeding?
What is hemp extract, and how is it different from cannabis?
Are there any serious side effects I should watch for?
Does this product actually work for the reasons it's sold?
What are the inactive ingredients, and are there fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CBN Tablets 1000 mg THC-Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CBN Tablets 1000 mg THC-Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CBN Tablets 1000 mg THC-Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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