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Dietary supplement

Copper Sebacate Ingredients & Drug Interactions

by Source Naturals

Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Copper Sebacate is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 31 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Copper Sebacate by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Copper Sebacate is a single-ingredient supplement containing copper, a mineral your body needs in small amounts for healthy nerves, bones, and immune function. The tablet also contains inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate, stearic acid, silica, and magnesium stearate — these are fillers and binders that hold the tablet together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Copper cofactor for enzyme systems and hemoglobin synthesis.
  • We looked for evidence on: Copper deficiency, Cardiovascular disease (CVD), Wound healing, Osteoporosis, Collagen formation, Energy production — and 1 related terms.
  • The strongest evidence on file: Copper is rated "Likely Effective" for Copper deficiency (Natural Medicines).
  • Also on file: Copper is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis, Cardiovascular disease (CVD), Wound healing.

Copper supplementation is likely effective for treating copper deficiency, which is uncommon but can happen in people with certain digestive disorders or those taking high doses of zinc for long periods. For Alzheimer disease, the evidence suggests copper is possibly ineffective.

The data we hold doesn't establish reliable evidence for acne, chemotherapy-induced anemia, or brain tumors, so we can't say whether it helps with those.

The evidence, ingredient by ingredient Copper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is generally well tolerated in the amounts found in food and standard supplements. However, excess copper can be toxic, so don't exceed recommended doses without medical guidance.

Copper is needed during pregnancy and lactation, but stick to recommended amounts and avoid high-dose supplements unless your doctor advises otherwise. Rarely, copper can cause contact dermatitis (skin inflammation and irritation), which was reported in a small number of children in clinical trials.

There's also evidence from observational studies that people with diabetes tend to have higher blood copper levels than those without diabetes, though it's not clear whether elevated copper contributes to diabetes development or worsening.

Side effects, ingredient by ingredient Copper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 31 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check your medications against these: penicillamine (a Moderate interaction — separate dosing by at least 2 hours), and oral contraceptives or birth control pills (a Minor interaction that may raise your copper levels). Use the search tool on this page to verify your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Copper Sebacate works well if you have a documented copper deficiency and your doctor has recommended supplementation. If you take penicillamine for Wilson disease or rheumatoid arthritis, or if you're on birth control pills, check with your pharmacist before starting.

For other uses, the evidence isn't strong enough to recommend it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Copper Sebacate, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078008835
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Feb 26, 2020
DSLD ID 213670
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Copper Sebacate by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
021078008835
IngredientAmount% DV
Copper3 mg150%

Other ingredients: Microcrystalline Cellulose, Dibasic Calcium Phosphate, Stearic Acid, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

22 mg

Copper is important as a cofactor for many enzyme systems (including superoxide dismutase [S.O.D.] and other antioxidants), as a catalyst in the synthesis of hemoglobin, and in collagen formation. Copper also helps in energy production, aids in iron metabolism, and protects nerve fibers.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 tablet daily with a meal.

Precautions

Note: If you are pregnant, may become pregnant, breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

Formulation

Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Copper Sebacate by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Copper Sebacate by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Copper

Interacts with
31 drugs
3 mg per serving Form: Copper Sebacic Acid Complex

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dibasic Calcium Phosphate, Stearic Acid, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Copper Sebacate by Source Naturals Drug Interactions

Want to check YOUR meds against Copper Sebacate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
31Drugs
1 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Each ingredient & the kinds of drugs it affects

For each ingredient in Copper Sebacate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Copper Sebacate, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Copper Sebacate by Source Naturals: Common Questions

Does Copper Sebacate by Source Naturals interact with any medications?
Yes. Based on its ingredients, Copper Sebacate has a known interaction with 31 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Copper Sebacate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is copper safe to take during pregnancy?
Copper is likely safe and actually needed during pregnancy, but stick to recommended amounts. Avoid high-dose supplements unless your doctor advises it. The safety data supports normal supplemental amounts, not megadoses.
Can I take copper if I'm breastfeeding?
Yes, recommended amounts of copper are considered likely safe during lactation. As with pregnancy, don't exceed normal supplement doses without medical guidance.
What is copper deficiency, and how would I know if I have it?
Copper deficiency is a shortage of this mineral in your body, which is uncommon but can occur in people with certain digestive disorders or those taking very high doses of zinc. Symptoms include nerve problems and weak bones, but diagnosis requires a blood test from your doctor.
Can copper help with Alzheimer disease?
The evidence suggests copper is possibly ineffective for Alzheimer disease, so we can't recommend it for that purpose based on the data we hold.
Are there any side effects from taking copper?
Copper is generally well tolerated at recommended doses. Rarely, it can cause contact dermatitis (skin irritation). In people with diabetes, copper levels tend to be higher naturally, though it's unclear if that matters clinically.
What are the inactive ingredients in this tablet?
The tablet contains microcrystalline cellulose, dibasic calcium phosphate, stearic acid, silica, and magnesium stearate — standard fillers and binders that don't add therapeutic benefit but help hold the tablet together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Copper Sebacate is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Copper Sebacate label
Go deeper

The Full Monographs Behind Copper Sebacate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Copper Sebacate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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