CoQ10+ Food Complex Ingredients & Drug Interactions
by New Chapter
What is this page for?
First and foremost: checking CoQ10+ Food Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CoQ10+ Food Complex is a dietary supplement by New Chapter with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are CoQ10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CoQ10+ Food Complex by New Chapter
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CoQ10+ Food Complex by New Chapter
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: CoQ10 (coenzyme Q10), a compound your body naturally makes and stores in your cells, where it helps produce energy. CoQ10 also acts as an antioxidant.
The capsule itself contains several inactive ingredients—culture media, maltodextrin, gum acacia, lactic acid bacteria, papain, bromelain, rice, and capsule materials—that serve as fillers and binders.
Does it work?
Couldn't assess
CoQ10 is likely effective for treating CoQ10 deficiency. The evidence suggests it's possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy (a type of nerve damage from diabetes).
For other uses, the evidence we hold doesn't establish effectiveness.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults. In clinical studies, no serious adverse effects have been reported.
Gastrointestinal side effects—appetite suppression, diarrhea, nausea, heartburn—can occur but happen in less than 1% of people. Headache, dizziness, and insomnia have been reported less commonly; skin rash and itching are rare.
If you divide doses above 100 mg, you may reduce stomach upset. There isn't enough reliable safety data on CoQ10 in pregnancy, so the safety data advises against use unless your doctor advises otherwise.
Safety while breastfeeding hasn't been well studied; use caution and check with your doctor.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take warfarin or other blood thinners (Moderate concern), chemotherapy drugs like cyclophosphamide (Moderate concern), or blood pressure medications (Minor concern). CoQ10 may reduce the effectiveness of blood thinners and chemotherapy and may add to the blood-pressure-lowering effect of your medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 may help if you have a CoQ10 deficiency, fibromyalgia, migraines, heart failure, or diabetic nerve damage. If you take warfarin, chemotherapy drugs, or blood pressure medication, talk with your doctor or pharmacist before starting—this product could affect how those work.
It's generally well tolerated, though stomach upset is possible in a small number of people.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 27, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CoQ10+ Food Complex, straight from the product label.
| Brand | New Chapter |
|---|---|
| Net contents | 30 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 27, 2014 |
| DSLD ID | 38366 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CoQ10+ Food Complex by New Chapter, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| CoQ10 | 22 mg | -- |
Other ingredients: Culture Media, Maltodextrin, organic Gum Acacia, Lactic Acid bacteria, Papain, Bromelain, organic milled Rice, Hypromellose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Backed by human and in vitro testing, New Chapter(R)’s dual-cultured CoQ10+ demonstrated superior antioxidant activity over the chemical isolate form of CoQ10.*
(C) 2014 New Chapter, Inc.
Formula
Probiotic-cultured nutrients provide a broad spectrum of phytonutrients and ferment metabolites, including isoflavones and beta-glucans.
Contains: Fermented soy and fermented wheat (as food source for Saccharomyces cerevisiae).
General Statements
Once-daily formula is easy to take, easy to digest, and can be taken anytime—even on an empty stomach!
Please recycle this bottle after use.
NON-GMO VERIFIED FORMULA
WHOLE PROBIOTIC NUTRIENTS
Whole-Food Complexed CoQ10 for Antioxidant & Cardiovascular Support*
PROBIOTIC. WHOLE. NON-GMO PROJECT VERIFIED.
CoQ10+ Food Complex delivers essential nutrients in a safe and active form within the infinite complexity of food. Whole-food complexed CoQ10 combats oxidative stress and supports multiple facets of cardiovascular health.*
Precautions
If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare practitioner prior to using this product.
Contains: Fermented soy and fermented wheat (as food source for Saccharomyces cerevisiae).
Caution: As with any dietary or herbal supplement, you should advise your healthcare practitioner of the use of this product.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
NON GMO Project VERIFIED
UO
Suggested/Recommended/Usage/Directions
Can be taken on an empty stomach
Suggested use: One capsule daily. Can be taken anytime, even on an empty stomach.
FDA Statement of Identity
DIETARY SUPPLEMENT
Formulation
Gluten free; 100% vegetarian; no artificial flavors or colors.
The wheat has been processed to allow this food to meet the Food and Drug Administration (FDA) requirements for gluten-free foods.
Gluten free; 100% vegetarian; no artificial flavors or colors.
General
0695-A02
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CoQ10+ Food Complex by New Chapter label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CoQ10+ Food Complex by New Chapter
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
CoQ10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
CoQ10 monograph & interactionsOther (inactive) ingredients: Culture Media, Maltodextrin, Organic Gum Acacia, Lactic Acid bacteria, Papain, Bromelain, Organic milled Rice, Hypromellose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
CoQ10+ Food Complex by New Chapter Drug Interactions
HelloPharmacist Interaction Report
CoQ10+ Food Complex by New Chapter contains CoQ10, which interacts with blood thinners (warfarin), chemotherapy drugs (alkylating agents), and blood pressure medications.
The most serious concern is warfarin: CoQ10 may reduce how well this blood thinner works, and a small number of cases have been reported where people taking both saw decreased warfarin effectiveness. If you're on warfarin, this is something to discuss with your doctor before starting.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 may also interfere with alkylating chemotherapy drugs—a class of cancer medications that work partly by creating damaging molecules (free radicals). Because CoQ10 is an antioxidant, it theoretically could shield tumor cells from that effect, potentially reducing how well the drug works.
If you're undergoing chemotherapy, check with your oncologist first.
CoQ10 may also lower blood pressure on its own, so if you take blood pressure medication, there's a small chance of additive effects—meaning your blood pressure could drop more than intended. Altogether, these interactions span 198 individual medications.
Use the search tool below to check your exact medications before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CoQ10+ Food Complex?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CoQ10+ Food Complex interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in CoQ10+ Food Complex interact with drugs. Each result below shows which ingredient is responsible. CoQ10
AltretamineHexalen
How Altretamine interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coq10 + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coq10 + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with CoQ10+ Food Complex — through 1 ingredient. Tap an ingredient for the detail:
Coq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CoQ10+ Food Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
CoQ10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CoQ10+ Food Complex, from the product label.
New Chapter
See all New Chapter products- Name
- NEW CHAPTER, INC.
- Street Address
- 90 TECHNOLOGY DRIVE
- City
- BRATTLEBORO
- State
- VT
- ZipCode
- 05301
CoQ10+ Food Complex by New Chapter: Common Questions
Does CoQ10+ Food Complex by New Chapter interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will CoQ10 interfere with my warfarin?
Can I take this if I'm undergoing chemotherapy?
What side effects might I experience?
Is CoQ10 safe during pregnancy?
Is it safe while breastfeeding?
Will this lower my blood pressure too much if I'm already on blood pressure medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CoQ10+ Food Complex is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CoQ10+ Food Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CoQ10+ Food Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
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