Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Fish Oil +Co Q-10 Ingredients & Drug Interactions

by GNC Triple Strength

Fish Oil +Co Q-10 label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fish Oil +Co Q-10 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fish Oil +Co Q-10 is a dietary supplement by GNC Triple Strength with 3 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Fish Oil +Co Q-10 by GNC Triple Strength

Ask about any prescription or over-the-counter medication and we check it for interactions with Fish Oil +Co Q-10 by GNC Triple Strength — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fish Oil +Co Q-10 by GNC Triple Strength

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients. Fish oil supplies eicosapentaenoic acid and docosahexaenoic acid, two omega-3 fatty acids.

The third active is coenzyme Q10, a compound your cells use to produce energy. The softgel also contains inactive ingredients — fish body oil, gelatin, glycerin, chlorophyll, titanium dioxide, and an enteric coating — to hold and protect the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports heart health and normal cholesterol levels.
  • We looked for evidence on: Angina, Cardiovascular disease (CVD), Congestive heart failure (CHF), Hyperlipidemia, Hypertension, Hypertrophic cardiomyopathy — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF) (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Possibly Effective" for Myocardial infarction (MI).
  • Also on file: Coenzyme Q10 is rated "Insufficient Reliable Evidence To Rate" for Angina, Cardiovascular disease (CVD), Hyperlipidemia, Hypertension, and more.

Coenzyme Q10 is likely effective for correcting coenzyme Q10 deficiency. It's possibly effective for fibromyalgia, migraine headaches, congestive heart failure, and diabetic neuropathy — meaning some clinical evidence supports it, but more research is needed.

We don't hold effectiveness data for the fish oil components in this product.

The evidence, ingredient by ingredient Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coenzyme Q10 is generally well tolerated by most adults when used as directed. In clinical studies, no serious adverse effects have been reported.

The most common side effects are mild gastrointestinal issues — appetite suppression, diarrhea, heartburn, nausea, vomiting — occurring in less than 1% of people; dividing daily doses above 100 mg can help minimize these. Headache, dizziness, insomnia, and skin itching have been reported rarely.

Safety in pregnancy hasn't been well studied, so the data advises caution — talk with your doctor before taking this product if you're pregnant. Safety while breastfeeding also hasn't been well studied; use caution and check with your doctor.

Side effects, ingredient by ingredient Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coenzyme Q10.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on chemotherapy (especially alkylating agents like cyclophosphamide) — coenzyme Q10 may reduce how well they work. Also flag it if you take warfarin or other blood thinners, since coenzyme Q10 may weaken their effect.

If you're on blood pressure medication, let your provider know, since coenzyme Q10 may add to its effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking to support heart health, migraine management, or energy production — but it's not a substitute for proven medical treatment. If you take warfarin, chemotherapy, or blood pressure medication, you need to clear this with your own doctor or pharmacist first.

Talk it over with them before you start, especially if you're pregnant, breastfeeding, or on any prescription drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fish Oil +Co Q-10, straight from the product label.

Brand GNC Triple Strength
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 831
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fish Oil +Co Q-10 by GNC Triple Strength, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
IngredientAmount% DV
Calories15 {Calories}--
Calories from Fat15 {Calories}--
Total Fat1.5 g2%
Eicosapentaenoic Acid647 mg--
Docosahexaenoic Acid253 mg--
Coenzyme Q-10100 mg--

Other ingredients: Fish Body Oil, Gelatin, Glycerin, Chlorophyll, Titanium Dioxide, Enteric Coating

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formulation

No Sugar, No Starch, No Artificial Colors, No Artificial Flavors, No Preservatives, No Wheat, No Gluten, No Corn, No Dairy, Yeast Free.

Precautions

KEEP OUT OF REACH OF CHILDREN.

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Storage

Store in a cool, dry place.

General Statements

900 mg total omega-3 fatty acids 100 mg of Co Q-10 Supports heart health and normal, healthy cholesterol levels* Purified • Controls fishy burps^

ACTUAL SIZE

Enteric Coated

Fish oils naturally provide the heart-healthy omega-3 fatty acids EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid). One enteric coated softgel capsule combines 100 mg of coenzyme 0-10 with 900 mg of omega-3 fatty acids; 647 mg of EPA and 253 mg of DHA. “The enteric coating allows the softgel capsule to break down and absorb in the small intestine. This controls or reduces the fishy burps. A landmark study involving over 11,000 participants has confirmed the major benefits of fish oil on cardiovascular health. The omega-3 fatty acids found in fish oil are necessary for heart heaIth.* They help support normal, healthy cholesterol levels and are necessary inthe maintenance of normal blood pressure.* Individually, EPA is important for circulatory system health, and DHA provides support for healthy triglyceride IeveIs.* Coenzyme 0-10 is an important antioxidant that is an essential component of your hearl‘s energy producing systemf It helps support a healthy cardiovascular system.* The fish oil in GNC Triple Strength Fish Oil plus Co 0-10 has been purified and manufactured for freshness and found to be free of detectable levels of mercury, cadmium, lead and PCBs. We use only the best quality ingredients derived from wild, deep ocean fish.

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

GNC QUALITY COMMITMENT GNC, the leader in the development and manufacture of dietary supplements, is committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately to our stores, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.

Please recycle this box.

Potency of Coenzyme Q-10 verified by GNC procedure #5012. Conforms to USP <2091> for weight.

General

CODE 885411 AMG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one softgel capsule up to two times daily with food.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fish Oil +Co Q-10 by GNC Triple Strength label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fish Oil +Co Q-10 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fish Oil +Co Q-10 by GNC Triple Strength

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Eicosapentaenoic Acid

647 mg per serving

Docosahexaenoic Acid

253 mg per serving

Coenzyme Q-10

Interacts with
198 drugs
100 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q-10 monograph & interactions

Other (inactive) ingredients: Fish Body Oil, Gelatin, Glycerin, Chlorophyll, Titanium Dioxide, Enteric Coating. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fish Oil +Co Q-10 by GNC Triple Strength Drug Interactions

Want to check YOUR meds against Fish Oil +Co Q-10?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
26 Moderate 172 Minor

Ingredients driving the most interactions

Coenzyme Q-10 198

Individual Drug Interactions

The ingredients in Fish Oil +Co Q-10 interact with 198 drugs. Click any drug to see the details.

1 of the 3 ingredients in Fish Oil +Co Q-10 interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10

Each ingredient & the kinds of drugs it affects

For each ingredient in Fish Oil +Co Q-10 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coenzyme Q-103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q-10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fish Oil +Co Q-10, from the product label.

GNC Triple Strength

See all GNC Triple Strength products
Phone Number
1-888-462-2548
Pharmacist Counseling Corner

Fish Oil +Co Q-10 by GNC Triple Strength: Common Questions

Does Fish Oil +Co Q-10 by GNC Triple Strength interact with any medications?
Yes. Based on its ingredients, Fish Oil +Co Q-10 has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fish Oil +Co Q-10 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is coenzyme Q10 safe to take long-term?
Coenzyme Q10 is generally well tolerated in adults when used as directed, with no serious adverse effects reported in clinical studies. Most side effects are mild gastrointestinal ones that happen in less than 1% of people. Talk with your pharmacist about what duration makes sense for your needs.
Can I take this if I'm pregnant?
There isn't enough reliable safety data on coenzyme Q10 in pregnancy, so it's best to avoid it unless your doctor advises otherwise. Check with your own doctor before starting.
What are the most common side effects?
Mild gastrointestinal side effects like appetite suppression, diarrhea, heartburn, nausea, and vomiting occur in less than 1% of patients and are usually manageable. If you take more than 100 mg daily, splitting the dose can help reduce these.
Can coenzyme Q10 actually lower blood pressure?
Some clinical research shows coenzyme Q10 can significantly lower blood pressure, though other studies have had conflicting results. If you're already on blood pressure medication, this is something to discuss with your doctor before starting.
Is this product effective for heart health?
Coenzyme Q10 is possibly effective for congestive heart failure — meaning some clinical evidence supports it, but more research is needed. It's not a replacement for medications your doctor has prescribed.
What about the fish oil in this product — does it interact with medications?
We don't hold interaction data for the fish oil components (eicosapentaenoic acid and docosahexaenoic acid), so we can't check them against your medications. Ask your pharmacist or doctor about any fish oil-specific concerns.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fish Oil +Co Q-10 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fish Oil +Co Q-10 label
Go deeper

The Full Monographs Behind Fish Oil +Co Q-10’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

Fish Oil +Co Q-10's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 40 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  30. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  31. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
  32. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
  33. Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
  34. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  35. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
  36. Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
  37. Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
  38. Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
  39. Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
  40. Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed

See these in context on the Coenzyme Q10 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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