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Dietary supplement

Full Spectrum Blessed Thistle 400 mg Ingredients & Drug Interactions

by Swanson

Full Spectrum Blessed Thistle 400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Full Spectrum Blessed Thistle 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Full Spectrum Blessed Thistle 400 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, boosting bile flow, general bitter tonic.Based on those ingredients, 36 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blessed thistle. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Full Spectrum Blessed Thistle 400 mg by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum Blessed Thistle 400 mg by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Full Spectrum Blessed Thistle 400 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: blessed thistle at 400 mg per capsule. Blessed thistle is an herb traditionally used to support digestion.

The capsules also contain inactive ingredients—gelatin, stearic acid, magnesium stearate, and silica—which are standard binders and capsule materials.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Blessed Thistle's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy digestion and women's health.
  • We looked for evidence on: Dyspepsia, appetite, bile flow, lactation support.
  • The closest evidence on file: Blessed Thistle is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for blessed thistle in treating indigestion (dyspepsia) is insufficient to rate, according to the data we hold. There isn't enough reliable research to say whether it actually works for that purpose.

If you're considering it for digestive support, talk with your pharmacist about what the evidence does and doesn't show.

The evidence, ingredient by ingredient Blessed Thistle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blessed thistle is often well tolerated in small amounts, but human safety data are limited. Larger doses can cause nausea or vomiting, and doses above 5 grams per cup of tea may cause stomach irritation.

Some people sensitive to the ragweed family (Asteraceae) may have an allergic reaction if exposed topically, such as rash or dermatitis. Safety data for breastfeeding haven't been well studied, so check with your doctor first if you're nursing.

Blessed thistle is best avoided during pregnancy because it's traditionally thought to affect the uterus and lacks solid safety data.

Side effects, ingredient by ingredient Blessed Thistle

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blessed Thistle.
  • The most serious interaction on file is rated Minor.
  • For scale: 36 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take medications to reduce stomach acid—H2-blockers, antacids, or proton pump inhibitors—check with us before adding blessed thistle. The herb may make these drugs less effective because it's reported to increase stomach acid.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Blessed thistle may be worth discussing with your pharmacist if you're looking for traditional digestive support, but the evidence of its effectiveness is limited. If you take H2-blockers, antacids, or PPIs for stomach acid, this product could interfere with them—check your exact medications before starting.

Anyone pregnant should avoid it, and nursing mothers should ask their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Blessed Thistle 400 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614116938
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 308542
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Blessed Thistle 400 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
087614116938
IngredientAmount% DV
Blessed thistle400 mg--

Other ingredients: Gelatin, Stearic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Traditionally used to support healthy digestion Traditional women's health tonic Full Spectrum whole herb formula

Digestive health

Brand IP Statement(s)

Swanson Science-backed quality since 1969

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule two to three times per day with water.

Precautions

Warning: For adults only. Keep out of reach of children.

Do not take this product if you are pregnant or nursing or if you have ulcers. Consult your healthcare provider if you are taking medication or have a medical condition.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Formula

Blessed Thistle 400 mg per capsule

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Full Spectrum Blessed Thistle 400 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Full Spectrum Blessed Thistle 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Full Spectrum Blessed Thistle 400 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Blessed thistle

Interacts with
36 drugs
400 mg per serving

Blessed thistle is a bitter herb traditionally used to stimulate appetite and ease mild digestive complaints. High-quality human studies are lacking,...

Blessed thistle monograph & interactions

Other (inactive) ingredients: Gelatin, Stearic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Blessed Thistle 400 mg by Swanson Drug Interactions

Want to check YOUR meds against Full Spectrum Blessed Thistle 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
36Drugs
36 Minor

Ingredients driving the most interactions

Blessed thistle 36

Individual Drug Interactions

The ingredients in Full Spectrum Blessed Thistle 400 mg interact with 36 drugs. Click any drug to see the details.

1 of the 1 ingredient in Full Spectrum Blessed Thistle 400 mg interact with drugs. Each result below shows which ingredient is responsible. Blessed thistle

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Blessed Thistle 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blessed thistle3 drug types · 36 drugs

Antacids

Theoretically, blessed thistle might decrease the effectiveness of antacids.
There are reports that blessed thistle increases stomach acid.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, blessed thistle might decrease the effectiveness of H2-blockers.
There are reports that blessed thistle increases stomach acid.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, blessed thistle might decrease the effectiveness of PPIs.
There are reports that blessed thistle increases stomach acid.

Likelihood Possible Evidence D
Blessed thistle full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Full Spectrum Blessed Thistle 400 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Full Spectrum Blessed Thistle 400 mg by Swanson: Common Questions

Does Full Spectrum Blessed Thistle 400 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Full Spectrum Blessed Thistle 400 mg has a known interaction with 36 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Blessed Thistle 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No. Blessed thistle is traditionally thought to affect the uterus and lacks solid safety data in pregnancy, so it's best avoided. Talk with your doctor before using any herbal supplement while pregnant.
Is it safe while breastfeeding?
Blessed thistle has been used traditionally to support milk supply, but safety hasn't been well studied. Check with your doctor first rather than starting on your own.
What are the side effects?
In normal doses, blessed thistle is often well tolerated. Larger doses—especially above 5 grams per cup of tea—can cause stomach irritation, nausea, or vomiting. People allergic to ragweed or related plants may have a skin reaction if the herb touches their skin.
Does blessed thistle actually help with digestion?
The evidence we hold isn't strong enough to say it works for indigestion. There isn't reliable research backing its use for that purpose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum Blessed Thistle 400 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Blessed Thistle 400 mg label
Go deeper

The Full Monographs Behind Full Spectrum Blessed Thistle 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blessed Thistle

Interacts with 36 drugs

Blessed thistle is a bitter herb traditionally used to stimulate appetite and ease mild digestive complaints. High-quality human studies are lacking, so its benefits are not well proven. It...

Read the full Blessed Thistle monograph →
Sources

Sources & How We Checked

Full Spectrum Blessed Thistle 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blessed Thistle 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Blessed Thistle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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