Blessed Thistle - Prevpac (Lansoprazole, Amoxicillin, Clarithromycin) Interaction
Herbal: Blessed Thistle
Also Known As: Cnicus benedictus, Carbenia Benedicta, Cardo Bendito, Cardo Santo, Carduus, Chardon Béni, Chardon Bénit, Chardon Marbré, Cnici Benedicti Herba, Cnicus, Holy Thistle, Safran Sauvage, St. Benedict Thistle, Spotted Thistle
Drug: Lansoprazole, Amoxicillin, Clarithromycin
Brand names:
Prevpac
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Lansoprazole, Amoxicillin, Clarithromycin is classified as belonging to the following category: Proton Pump Inhibitors (Ppis)
Theoretically, blessed thistle might decrease the effectiveness of PPIs.
There are reports that blessed thistle increases stomach acid.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Blessed Thistle Overview
Blessed thistle (Cnicus benedictus) is an herb with historical uses in traditional medicine and dietary supplements. It is recognized for its distinctive appearance, featuring spiny leaves and yellow flowers. In traditional herbal practices, blessed thistle has been employed for digestive support and as a tonic. Within dietary supplements, blessed thistle may be included for its potential health benefits, such as supporting digestion and promoting overall wellness.
Blessed Thistle - More Interactions
Blessed Thistle interacts with 36 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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