Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Full Spectrum CBD Oil 30 mg Ingredients & Drug Interactions

by NuLeaf Naturals

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Full Spectrum CBD Oil 30 mg is a dietary supplement by NuLeaf Naturals with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic virgin Hemp seed oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Full Spectrum CBD Oil 30 mg by NuLeaf Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Full Spectrum Hemp Aerial Parts Extract” is listed as a grouped ingredient — the label gives one combined amount (30 mg) without saying how much of each component you get.

This product contains 2 active ingredients: organic virgin hemp seed oil and a full spectrum hemp aerial parts extract. Hemp seed oil is the pressed oil from hemp seeds and contains fatty acids and proteins.

The full spectrum extract captures multiple compounds from the aerial (above-ground) parts of the hemp plant. The product contains no inactive fillers — just these active hemp components in liquid form.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish this product's effectiveness for any condition. Hemp seed oil has been studied for constipation, eczema, and high cholesterol, but in each case the data is insufficient to rate whether it really works.

If you're considering this oil for a specific health concern, talk with your doctor or pharmacist about what the current evidence shows.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods are generally well tolerated, but concentrated extracts like this supplement are much less studied, so caution is advised. In larger amounts, hemp seed oil appears to be well tolerated orally.

That said, rare serious side effects have been reported — anaphylaxis, allergic reactions (swelling, breathing trouble, hives), and in one case elevated liver enzymes and hepatitis in a young child given very high-dose hemp extract. Allergy to hemp seed is uncommon but can occur, especially on first exposure.

We have no data on whether this product is safe in pregnancy or while breastfeeding — there's not enough information to know either way. Talk with your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use estrogen-based hormone therapy (Moderate interaction risk). Also double-check if you take blood pressure medications, blood thinners, or drugs metabolized through your liver's CYP1A2 or CYP3A4 pathways — these carry Minor interaction risks.

Your pharmacist can run your exact medication list through our tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This hemp seed oil product is generally well tolerated at normal doses, but its interactions with hormone therapy, blood pressure drugs, blood thinners, and certain medications your liver breaks down deserve attention. If you take any prescription medications — especially hormones, blood pressure meds, or blood thinners — check them against this product with your doctor or pharmacist before starting.

Concentrated hemp extracts are less well studied than food amounts, so caution is fair.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum CBD Oil 30 mg, straight from the product label.

Brand NuLeaf Naturals
Net contents 0.17 Fluid Ounce(s); 5 mL
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 277846
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum CBD Oil 30 mg by NuLeaf Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
0.5 mL
Servings per container
10
IngredientAmount% DV
organic virgin Hemp seed oil436 mg--
Full Spectrum Hemp Aerial Parts Extract30 mg--
Cannabinoids4 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Full Spectrum CBD Oil 30 mg per serving 300 mg per bottle

Made with organic hemp

Full spectrum Our proprietary genetics allow us to naturally create a whole plant CBD extract that is highly concentrated in CBD and contains significant amounts of secondary cannabinoids like CBC, CBG, CBN, and more. Cannabinoids work synergistically with each other and are more effective when they are found together versus when they are isolated. This is known as the entourage effect.

FDA Statement of Identity

Hemp Supplement Oil with Dropper

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use Adults: Take ten drops daily or as needed. Shake well before using.

Precautions

As with any supplement, consult your physician before use if you are pregnant, nursing, have or suspect a medical condition, or are taking any medications.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Formulation

Life healthier & happier naturally Since 2014 NuLeaf Naturals has been committed to creating the world's highest quality CBD products in their most pure and potent form. Our full spectrum CBD oil contains no additives and the only ingredient is organic hemp. Our mission is to create premium cannabinoid wellness products we would not only take ourselves but also share with our family and friends.

Supercharge your ECS Cannabinoid receptors located throughout the body are part of the endocannabinoid system (ECS), which is involved in a variety of physiological processes. When absorbed by the body, CBD increases the ECS's ability to promote balance and optimal health. CBD is non-toxic and non-intoxicating.

Lab verified Full spectrum GMP certified CO2 extraction

Vegan

Organic & natural 100% organic Colorado hemp grown with fresh Rocky Mountain water and harvested at peak perfection.

CO2 extracted We use advanced subcritical and super-critical CO2 extraction to obtain a complete range of cannabinoids, terpenes, essential oils, and other beneficial phytonutrients. This yields a more potent blend that requires no harsh chemical solvents. Lab verified To ensure a safe, consistent, and effective product, we use independent labs to confirm our CBD products are free from pesticides, herbicides, mold, fungi, heavy metals, and mycotoxins. Our testing also guarantees our products contain the optimal amount of cannabinoids and terpenes.

Our full spectrum CBD oil contains no additives and the only ingredient is organic hemp.

Made with organic hemp

General Statements

Lab results

See for yourself

Full Spectrum CBD Oil 30 mg by NuLeaf Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Full Spectrum CBD Oil 30 mg by NuLeaf Naturals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container10 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic virgin Hemp seed oil

Interacts with
938 drugs
436 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Organic virgin Hemp seed oil monograph & interactions

Full Spectrum Hemp Aerial Parts Extract

Interacts with
938 drugs
30 mg per serving Form: Cannabidiol

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Full Spectrum Hemp Aerial Parts Extract monograph & interactions
  • › Cannabinoids

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum CBD Oil 30 mg by NuLeaf Naturals Drug Interactions

Want to check YOUR meds against Full Spectrum CBD Oil 30 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum CBD Oil 30 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic virgin Hemp seed oil6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Full Spectrum CBD Oil 30 mg, from the product label.

NuLeaf Naturals

See all NuLeaf Naturals products
Name
NuLeaf Naturals, LLC
City
Denver
State
CO
ZipCode
80202
Phone Number
1.720.372.4842
Web Address
NuLeafNaturals.com
Pharmacist Counseling Corner

Full Spectrum CBD Oil 30 mg by NuLeaf Naturals: Common Questions

Does Full Spectrum CBD Oil 30 mg by NuLeaf Naturals interact with any medications?
Yes. Based on its ingredients, Full Spectrum CBD Oil 30 mg has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum CBD Oil 30 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does hemp seed oil actually do anything, or is this just a trend?
We don't have enough reliable evidence to say whether it works for any particular condition yet. Hemp seed has been studied for constipation, eczema, and cholesterol, but the data so far is insufficient to rate its effectiveness. That doesn't mean it won't help you — just that we can't confirm it from the research we hold.
Is hemp seed oil safe if I'm on a blood thinner like warfarin?
It's a Minor interaction risk — hemp seed oil may theoretically increase bleeding risk with blood thinners. Animal studies suggested this, but human studies didn't show the effect. Still, talk with your pharmacist or doctor before adding it, especially if you're on a blood thinner.
Can I take this if I'm on hormone therapy or birth control?
There's a Moderate interaction concern — hemp seed oil has estrogenic effects that may theoretically interfere with how your hormones work. Check with your doctor or pharmacist before starting, particularly if you're on estrogen-based therapy.
What are the actual side effects I might see?
Most people tolerate hemp seed oil without trouble. Rarely, allergic reactions (hives, facial swelling, breathing trouble) can happen, even on first exposure. Very rare cases of anaphylaxis have been reported, and one child given extremely high-dose hemp extract developed elevated liver enzymes. Allergy to hemp is uncommon but possible.
Is this safe during pregnancy or while breastfeeding?
We don't have enough information to say either way. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing — they can give you personalized advice based on your situation.
What's the difference between hemp seed oil and the full spectrum extract in this product?
Hemp seed oil is the pressed oil from the seeds and contains fatty acids and proteins. The full spectrum extract captures multiple compounds from the aerial parts of the plant. Together, they make up the 2 active ingredients here.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum CBD Oil 30 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum CBD Oil 30 mg label
Go deeper

The Full Monographs Behind Full Spectrum CBD Oil 30 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Full Spectrum CBD Oil 30 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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