Full Spectrum CBD Oil 30 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Full Spectrum CBD Oil 30 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Full Spectrum CBD Oil 30 mg is a dietary supplement by NuLeaf Naturals with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic virgin Hemp seed oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Full Spectrum CBD Oil 30 mg by NuLeaf Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum CBD Oil 30 mg by NuLeaf Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Full Spectrum CBD Oil 30 mg by NuLeaf Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: organic virgin hemp seed oil and a full spectrum hemp aerial parts extract. Hemp seed oil is the pressed oil from hemp seeds and contains fatty acids and proteins.
The full spectrum extract captures multiple compounds from the aerial (above-ground) parts of the hemp plant. The product contains no inactive fillers — just these active hemp components in liquid form.
Does it work?
Couldn't assess
The evidence we hold doesn't establish this product's effectiveness for any condition. Hemp seed oil has been studied for constipation, eczema, and high cholesterol, but in each case the data is insufficient to rate whether it really works.
If you're considering this oil for a specific health concern, talk with your doctor or pharmacist about what the current evidence shows.
How safe is it?
Well-documented data
Hemp seed foods are generally well tolerated, but concentrated extracts like this supplement are much less studied, so caution is advised. In larger amounts, hemp seed oil appears to be well tolerated orally.
That said, rare serious side effects have been reported — anaphylaxis, allergic reactions (swelling, breathing trouble, hives), and in one case elevated liver enzymes and hepatitis in a young child given very high-dose hemp extract. Allergy to hemp seed is uncommon but can occur, especially on first exposure.
We have no data on whether this product is safe in pregnancy or while breastfeeding — there's not enough information to know either way. Talk with your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
Moderate interaction found
Check before taking this product if you use estrogen-based hormone therapy (Moderate interaction risk). Also double-check if you take blood pressure medications, blood thinners, or drugs metabolized through your liver's CYP1A2 or CYP3A4 pathways — these carry Minor interaction risks.
Your pharmacist can run your exact medication list through our tool on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This hemp seed oil product is generally well tolerated at normal doses, but its interactions with hormone therapy, blood pressure drugs, blood thinners, and certain medications your liver breaks down deserve attention. If you take any prescription medications — especially hormones, blood pressure meds, or blood thinners — check them against this product with your doctor or pharmacist before starting.
Concentrated hemp extracts are less well studied than food amounts, so caution is fair.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Full Spectrum CBD Oil 30 mg, straight from the product label.
| Brand | NuLeaf Naturals |
|---|---|
| Net contents | 0.17 Fluid Ounce(s); 5 mL |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 277846 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Full Spectrum CBD Oil 30 mg by NuLeaf Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| organic virgin Hemp seed oil | 436 mg | -- |
| Full Spectrum Hemp Aerial Parts Extract | 30 mg | -- |
| Cannabinoids | 4 mg | -- |
Other ingredients: None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Full Spectrum CBD Oil 30 mg per serving 300 mg per bottle
Made with organic hemp
Full spectrum Our proprietary genetics allow us to naturally create a whole plant CBD extract that is highly concentrated in CBD and contains significant amounts of secondary cannabinoids like CBC, CBG, CBN, and more. Cannabinoids work synergistically with each other and are more effective when they are found together versus when they are isolated. This is known as the entourage effect.
FDA Statement of Identity
Hemp Supplement Oil with Dropper
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
Suggested Use Adults: Take ten drops daily or as needed. Shake well before using.
Precautions
As with any supplement, consult your physician before use if you are pregnant, nursing, have or suspect a medical condition, or are taking any medications.
Keep out of reach of children.
Storage
Store in a cool, dry place.
Formulation
Life healthier & happier naturally Since 2014 NuLeaf Naturals has been committed to creating the world's highest quality CBD products in their most pure and potent form. Our full spectrum CBD oil contains no additives and the only ingredient is organic hemp. Our mission is to create premium cannabinoid wellness products we would not only take ourselves but also share with our family and friends.
Supercharge your ECS Cannabinoid receptors located throughout the body are part of the endocannabinoid system (ECS), which is involved in a variety of physiological processes. When absorbed by the body, CBD increases the ECS's ability to promote balance and optimal health. CBD is non-toxic and non-intoxicating.
Lab verified Full spectrum GMP certified CO2 extraction
Vegan
Organic & natural 100% organic Colorado hemp grown with fresh Rocky Mountain water and harvested at peak perfection.
CO2 extracted We use advanced subcritical and super-critical CO2 extraction to obtain a complete range of cannabinoids, terpenes, essential oils, and other beneficial phytonutrients. This yields a more potent blend that requires no harsh chemical solvents. Lab verified To ensure a safe, consistent, and effective product, we use independent labs to confirm our CBD products are free from pesticides, herbicides, mold, fungi, heavy metals, and mycotoxins. Our testing also guarantees our products contain the optimal amount of cannabinoids and terpenes.
Our full spectrum CBD oil contains no additives and the only ingredient is organic hemp.
Made with organic hemp
General Statements
Lab results
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Full Spectrum CBD Oil 30 mg by NuLeaf Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Full Spectrum CBD Oil 30 mg by NuLeaf Naturals
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container10 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Organic virgin Hemp seed oil
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Organic virgin Hemp seed oil monograph & interactionsFull Spectrum Hemp Aerial Parts Extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Full Spectrum Hemp Aerial Parts Extract monograph & interactions- › Cannabinoids
Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Full Spectrum CBD Oil 30 mg by NuLeaf Naturals Drug Interactions
HelloPharmacist Interaction Report
NuLeaf Naturals Full Spectrum CBD Oil 30 mg contains hemp seed oil, which interacts with several medication types.
The most serious concern is with estrogens (hormone therapy) — hemp seed oil's estrogenic effects may theoretically interfere with how your hormones work, rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Hemp seed oil also carries Minor-severity interactions with blood pressure medications (antihypertensive drugs and ACE inhibitors), blood thinners (anticoagulant/antiplatelet drugs), and certain drugs your liver processes through CYP1A2 and CYP3A4 pathways. The blood pressure concern stems from animal research showing hemp seed protein can lower blood pressure; the blood thinner concern comes from animal data on platelet effects, though human studies didn't show the same result.
The liver-enzyme interactions are based on lab findings that hemp induces these metabolic pathways, which may reduce drug levels.
We could not check the Full Spectrum Hemp Aerial Parts Extract for interactions — its components aren't listed individually here. We also hold no interaction data for cannabinoids themselves.
Altogether, these interactions span 939 individual medications. Use the medication checker on this page to see if any of your drugs are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Full Spectrum CBD Oil 30 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Full Spectrum CBD Oil 30 mg interact with 938 drugs. Click any drug to see the details.
1 of the 2 ingredients in Full Spectrum CBD Oil 30 mg interact with drugs. Each result below shows which ingredient is responsible. organic virgin Hemp seed oil
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Full Spectrum CBD Oil 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Aerial Parts Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Full Spectrum CBD Oil 30 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic virgin Hemp seed oil
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Full Spectrum CBD Oil 30 mg, from the product label.
NuLeaf Naturals
See all NuLeaf Naturals products- Name
- NuLeaf Naturals, LLC
- City
- Denver
- State
- CO
- ZipCode
- 80202
- Phone Number
- 1.720.372.4842
- Web Address
- NuLeafNaturals.com
Full Spectrum CBD Oil 30 mg by NuLeaf Naturals: Common Questions
Does Full Spectrum CBD Oil 30 mg by NuLeaf Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does hemp seed oil actually do anything, or is this just a trend?
Is hemp seed oil safe if I'm on a blood thinner like warfarin?
Can I take this if I'm on hormone therapy or birth control?
What are the actual side effects I might see?
Is this safe during pregnancy or while breastfeeding?
What's the difference between hemp seed oil and the full spectrum extract in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Full Spectrum CBD Oil 30 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Full Spectrum CBD Oil 30 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Full Spectrum CBD Oil 30 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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