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Dietary supplement

Full Spectrum CBD Softgels Original Ingredients & Drug Interactions

by Green Roads

Full Spectrum CBD Softgels Original label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Full Spectrum CBD Softgels Original against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Full Spectrum CBD Softgels Original is a dietary supplement by Green Roads with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Full Spectrum Hemp Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Full Spectrum CBD Softgels Original by Green Roads

Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum CBD Softgels Original by Green Roads — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Full Spectrum CBD Softgels Original by Green Roads

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: full spectrum hemp extract — meaning it includes the whole range of compounds from the hemp plant, not just isolated cannabinoids. The softgels are filled with medium chain triglyceride oil (a type of fat that aids absorption), along with gelatin, glycerin, and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for full spectrum hemp extract isn't established in our data. We hold insufficient reliable evidence to rate it for constipation, eczema, or familial hypercholesterolemia — the conditions we have ratings for.

If you're considering this product for another reason, that doesn't mean it won't help, just that we don't have solid evidence on file for that use.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods and oils are generally well tolerated in normal amounts. Concentrated hemp extracts like this supplement are less studied, so caution is advised.

Serious adverse effects are rare but have been reported: occasional allergy or anaphylaxis (especially on first exposure), and very rare cases of liver enzyme changes or heart rhythm problems. A case of hepatitis was reported in a young child given very high doses.

We don't have safety data on file for pregnancy or breastfeeding. Because this is a concentrated extract and safety isn't well established, talk to your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check before starting if you take estrogens or hormone therapy (Moderate severity), or blood thinners, blood pressure medications, ACE inhibitors, or any drug metabolized by your liver's CYP1A2 or CYP3A4 pathways (all Minor severity). Hemp may interfere with how these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you've done your homework on hemp extract's benefits for your specific need. Before you start, check your medications — especially blood thinners, blood pressure drugs, hormone therapy, and any prescription metabolized by your liver.

If any of those apply, run them through the checker below or ask your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum CBD Softgels Original, straight from the product label.

Brand Green Roads
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 318783
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum CBD Softgels Original by Green Roads, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
IngredientAmount% DV
Full Spectrum Hemp Extract25 mg--

Other ingredients: Medium Chain Triglyceride Oil, Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Up to 0.3% THC 750mg CBD Total With MCT oil Full Spectrum CBD Softgels 25mg CBD/EA

These full-spectrum softgels deliver CBD plus a wide range of cannbinoids found naturally in hemp, all in one easy-to-take softgel.

Full spectrum CBD enhanced by other beneficial hemp compounds Up to 0.3% THC (Legal Limit)

Formulation

Moderate

Green Roads products are made with naturally occurring cannabinoids from hemp grown in the US.

General Statements

Your one-step daily CBD! Scan ME Scan to view independent lab results Pharmacist formulated Crafted with care

Full-spectrum extracts may offer the "entourage effect" in which multiple compounds synergize for greater effect. I love them because they are the easiest way to add CBD to your daily routine. Laura Fuentes, RPh/Co-founder Licensed compounding pharmacist

Please recycle

Keep box for all product facts.

Which Green Roads series is right for you? Isolate Purest form of CBD Zero THC No additional hemp compounds Broad spectrum CBD enhanced by other beneficial hemp compounds <0.07% THC

Go to greenroads.com for more products and info

Brand IP Statement(s)

Green Roads Enjoy your one-step way to OWN THE DAY!

Precautions

Warning This product contains a chemical (delta-9 tetrahydrocannabinol) known to the state of California to cause birth defects or other reproductive harm. For more information, go to www.p65warnings.ca.gov

May cause drowsiness. Tamper-evident, use only if seal is intact.

If you are pregnant, nursing, have any health conditions or are taking any medications, consult your healthcare practitioner before using this product.

Keep out of reach of children. Recommended for adults 18 and older.

Suggested/Recommended/Usage/Directions

Recommended Use: Take 1-2 softgels daily.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Full Spectrum CBD Softgels Original by Green Roads label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Full Spectrum CBD Softgels Original label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Full Spectrum CBD Softgels Original by Green Roads

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Full Spectrum Hemp Extract

Interacts with
938 drugs
25 mg per serving Form: Cannabinoid

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Full Spectrum Hemp Extract monograph & interactions

Other (inactive) ingredients: Medium Chain Triglyceride Oil, Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum CBD Softgels Original by Green Roads Drug Interactions

Want to check YOUR meds against Full Spectrum CBD Softgels Original?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Full Spectrum Hemp Extract 938

Individual Drug Interactions

The ingredients in Full Spectrum CBD Softgels Original interact with 938 drugs. Click any drug to see the details.

1 of the 1 ingredient in Full Spectrum CBD Softgels Original interact with drugs. Each result below shows which ingredient is responsible. Full Spectrum Hemp Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum CBD Softgels Original with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Full Spectrum Hemp Extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Full Spectrum Hemp Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Full Spectrum CBD Softgels Original, from the product label.

Green Roads

See all Green Roads products
Name
Green Roads
Web Address
greenroads.com
Pharmacist Counseling Corner

Full Spectrum CBD Softgels Original by Green Roads: Common Questions

Does Full Spectrum CBD Softgels Original by Green Roads interact with any medications?
Yes. Based on its ingredients, Full Spectrum CBD Softgels Original has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum CBD Softgels Original contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm pregnant or breastfeeding?
We don't have safety data on file for pregnancy or breastfeeding with hemp extracts. Because this is a concentrated supplement rather than a food amount, talk with your doctor or pharmacist before using it if you're pregnant, trying to conceive, or nursing.
Can hemp extract cause allergies?
Allergy to hemp seed is uncommon, but it does happen. Reactions can range from hives to facial swelling, shortness of breath, and anaphylaxis — particularly on first exposure. If you've never had hemp products before, be aware of this risk.
What does 'full spectrum' mean?
Full spectrum means the extract contains the whole range of compounds naturally found in hemp, not just one isolated ingredient. That includes cannabinoids, terpenes, and other plant compounds working together.
Is there evidence this works for what I want to use it for?
We hold insufficient evidence to rate hemp extract for constipation, eczema, or cholesterol. If you're considering it for another reason, we don't have effectiveness data on file — talk to your pharmacist about what research exists for your specific need.
Are there any fillers or other stuff in these softgels?
Yes — the softgels contain medium chain triglyceride oil (which helps your body absorb the extract), gelatin, glycerin, and purified water. These are inactive ingredients that give the softgel its form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum CBD Softgels Original is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum CBD Softgels Original label
Go deeper

The Full Monographs Behind Full Spectrum CBD Softgels Original’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Full Spectrum CBD Softgels Original's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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