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Dietary supplement

Giloy 250 mg Ingredients & Drug Interactions

by Vedic Supplements

Giloy 250 mg label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Giloy 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Giloy 250 mg is a dietary supplement by Vedic Supplements with 1 active ingredient. Its ingredients are commonly taken for immune support, fever, blood sugar support.Based on those ingredients, 612 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Giloy, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Giloy 250 mg by Vedic Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Giloy 250 mg by Vedic Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Giloy 250 mg by Vedic Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Giloy 250 mg contains one active ingredient: tinospora cordifolia powder, a plant used in traditional medicine. The tablet also holds inactive ingredients — microcrystalline cellulose, lactose, hydroxypropyl methylcellulose, and ethyl cellulose — which are binders and fillers that help hold the tablet together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Tinospora Cordifolia's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: For immunity.
  • We looked for evidence on: Allergic rhinitis (hay fever), Immune function, Infection resistance, Fever support.
  • The closest evidence on file: Tinospora Cordifolia is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).

According to the data we hold, tinospora cordifolia is possibly effective for type 2 diabetes — clinical research shows it can reduce fasting blood sugar and long-term sugar control markers. For allergic rhinitis (hay fever), asthma, athletic performance, cancer, and hepatitis, the evidence is insufficient to rate whether it works.

If you're considering this product for any of those other conditions, talk with your pharmacist or doctor about what the current science says.

The evidence, ingredient by ingredient Tinospora Cordifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, tinospora cordifolia is generally well tolerated, though headache and nasal pain were reported in trials. The main concern is liver injury — a rare but serious risk.

Case reports describe autoimmune hepatitis, acute hepatitis, worsening liver disease, and even acute liver failure in 49 patients after 42–90 days of use, sometimes requiring transplant or resulting in death. Because of this risk, use it cautiously and under guidance, and monitor your liver function if you take it long-term.

The safety data advises against use in pregnancy. There isn't enough reliable safety information to recommend it while breastfeeding, so talk with your doctor or pharmacist if you're nursing or trying to become pregnant.

Side effects, ingredient by ingredient Tinospora Cordifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tinospora Cordifolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 612 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Giloy, double-check any medications you take that are processed through your liver's CYP2D6, CYP2C19, CYP1A2, or CYP2C9 pathways (Moderate severity). Also flag diabetes medications and immunosuppressants — the herb may lower blood sugar dangerously or reduce how well immunosuppressants work.

Use the interaction checker below with your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Giloy may help with type 2 diabetes blood sugar control, but it carries a documented risk of liver injury and interacts with a wide range of medications through liver metabolism. If you take any prescription drugs — especially diabetes medications, immunosuppressants, or anything processed by your liver — check your exact medications with the tool on this page first.

Pregnant or breastfeeding? Skip it and talk to your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Giloy 250 mg, straight from the product label.

Brand Vedic Supplements
Barcode (UPC) 850049510189
Net contents 60 Tab(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336177
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Giloy 250 mg by Vedic Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
850049510189
IngredientAmount% DV
Giloy, Powder250 mg--

Other ingredients: Microcrystalline Cellulose, Lactose, Hydroxypropyl Methylcellulose, Ethyl Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

For comments/feedback: [email protected] 1-612-88-VEDIC The Vedic Store Scan with mobile camera C.No. RA574-AYU To explore our other range of products, visit our website or scan QR code www.TheVedicStore.com

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Product of India Pure & natural

For immunity

No artificial color

Suitable for Vegetarian

100% ayurvedic product

100% pure quality Inspired by ayurveda

Free from- gluten, flavor

100% veg

Seals/Symbols

GMP Certified Good Manufacturing Practice

Suitable for Vegetarian

Brand IP Statement(s)

Vedic Supplements Your Health Matters

Formula

Giloy 250 mg extract Heart leaved moonseed / Tinospora cordifolia Stem + extract

FDA Statement of Identity

Dietary Supplement

Precautions

Important information: This is not a medicinal product. If in doubt consult a doctor before taking food supplements. Food supplements must not be used as a substitute for a varied & balanced diet & a healthy lifestyle.

If you are pregnant, breastfeeding, or on any medication, please consult a doctor before use.

Keep away from the reach of children.

Suggested/Recommended/Usage/Directions

Dosage: Adults take 1 tablet twice daily after meals or as directed by a physician.

Recommended use: Around 4-6 months

Storage

Storage: Away from direct heat and sunlight. Store at room temperature. Re cap tightly after every use.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Giloy 250 mg by Vedic Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Giloy 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Giloy 250 mg by Vedic Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Giloy, Powder

Interacts with
612 drugs
250 mg per serving

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Ea...

Giloy, Powder monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Lactose, Hydroxypropyl Methylcellulose, Ethyl Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Giloy 250 mg by Vedic Supplements Drug Interactions

Want to check YOUR meds against Giloy 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
612Drugs
612 Moderate

Ingredients driving the most interactions

Giloy, Powder 612

Individual Drug Interactions

The ingredients in Giloy 250 mg interact with 612 drugs. Click any drug to see the details.

1 of the 1 ingredient in Giloy 250 mg interact with drugs. Each result below shows which ingredient is responsible. Giloy, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Giloy 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Giloy, Powder6 drug types · 612 drugs

Antidiabetes Drugs

Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.

Likelihood Possible Evidence D
Giloy, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Giloy 250 mg, from the product label.

Vedic Supplements

See all Vedic Supplements products
Name
The Vedic Store
City
New Brunswick
State
NJ
ZipCode
08901
Phone Number
1-612-888-3342
Web Address
www.TheVedicStore.com
Pharmacist Counseling Corner

Giloy 250 mg by Vedic Supplements: Common Questions

Does Giloy 250 mg by Vedic Supplements interact with any medications?
Yes. Based on its ingredients, Giloy 250 mg has a known interaction with 612 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Giloy 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Giloy actually help with diabetes?
Clinical research shows tinospora cordifolia is possibly effective for type 2 diabetes — it can reduce fasting blood sugar and long-term control markers. That said, it's not a replacement for your prescribed diabetes medications. Talk with your doctor about whether it fits your treatment plan.
What are the side effects?
When taken by mouth, tinospora cordifolia is generally well tolerated. The most common side effects reported in trials were headache and nasal pain. However, liver injury is a rare but serious concern — 49 cases have been reported after 42–90 days of use, with some requiring transplant or resulting in death.
Is it safe to take while pregnant or breastfeeding?
No — safety hasn't been established in pregnancy, so it's best avoided. There also isn't enough reliable safety information to recommend it while breastfeeding. Talk with your doctor or pharmacist if you're pregnant, trying to become pregnant, or nursing.
What exactly is Giloy?
Giloy is tinospora cordifolia, a plant used in traditional medicine. This 250 mg tablet delivers the powdered herb along with inactive binders and fillers to hold the tablet together.
Can I take this with my other medications?
Tinospora cordifolia affects how your liver processes many drugs — it could raise levels of medications metabolized through several liver pathways. It also interacts with diabetes drugs and immunosuppressants. Check your exact medications with the tool on this page before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Giloy 250 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Giloy 250 mg label
Go deeper

The Full Monographs Behind Giloy 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tinospora Cordifolia

Interacts with 612 drugs

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Early laboratory and small human studies s...

Read the full Tinospora Cordifolia monograph →
Sources

Sources & How We Checked

Giloy 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tinospora Cordifolia 16 references
  1. Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
  2. Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
  3. Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
  4. Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
  5. Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
  6. Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
  7. Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
  8. Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
  9. Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
  10. Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
  11. Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
  12. Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
  13. Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
  14. Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
  15. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
  16. May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.

See these in context on the Tinospora Cordifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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