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Dietary supplement

Glutamine Ingredients & Drug Interactions

by NutraBio

Glutamine label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine by NutraBio — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glutamine by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine, a naturally occurring amino acid. Glutamine plays a role in immune function, gut health, and muscle metabolism.

The powder form lets you control your dose easily. There are no inactive ingredients (fillers or binders) listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Muscle recovery and athletic performance support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Critical illness (trauma), Wound healing, Burns — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Burns, Radiation-induced diarrhea.

L-glutamine is effective for sickle cell disease. It's rated possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

The evidence for these other uses is still developing, so talk with your doctor about whether it fits your particular situation.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults. The most common side effects with oral use are gastrointestinal — belching, bloating, constipation, flatulence, nausea, vomiting, diarrhea, and stomach pain — along with headache, cough, and musculoskeletal pain.

Two cases of mania or hypomania have been reported in people with bipolar disorder taking up to 4 grams daily; one case of dizziness resolved when the dose was reduced. People with kidney or liver disease should use glutamine only under medical supervision.

Pregnancy is rated likely safe, but there isn't enough reliable safety data to recommend supplement doses while breastfeeding unless your doctor advises it.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your anticonvulsant medications before taking this product. Glutamine might theoretically reduce their effectiveness, though this hasn't been confirmed in patients.

Your pharmacist can help you assess the risk with your specific drug.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine may be worth considering if you have sickle cell disease or are recovering from surgery or critical illness, but talk with your doctor first. If you take anticonvulsant medication, check with your pharmacist before starting.

People with kidney or liver disease need medical supervision.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908230401
Net contents 17.6 Ounce(s); 1.1 Pound(s); 500 Gram(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 329377
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
100
UPC/BARCODE
649908230401
IngredientAmount% DV
L-Glutamine5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 1 level scoop (5 g) mixed with your favorite beverage 2 to 3 times daily. On training days take first serving 20 minutes prior to workout, second serving immediately following workout, second serving immediately following workout, and an optional third serving before sleep. On non-training days, space your servings evenly throughout the day with your last serving before sleep. For optimum results take in conjunction with NutraBio Creatine and Whey Protein Isolate.

Precautions

Warning: Keep out of reach of children. Not for use by individuals under the age of 18 years.

Do not use if pregnant or nursing. Consult a physician before use if you have a medical condition or are taking any medication.

Discontinue use two weeks prior to surgery.

Processed in a facility that also processes milk and tree nuts.

General Statements

"We let our E.T.H.I.C.s be our guide" Mark Glazier President CEO

From our facility to your shaker since 1996

Formulation

NB Ethics Efficacy Transparency Honesty Innovation Commitment

Made without gluten, lactose and GMOs.

Vegetarian

Seals/Symbols

Manufactured in our GMP & FDA Inspected Facility Made in USA with ingredients sourced worldwide

OU (Kosher)

Check. Verify. Trust. View independent lab results checkmysupps.com

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Pure grade amino acid

OU (Kosher)

FDA Statement of Identity

Amino Acid Supplement

Storage

This product is sold by weight not volume. Some settling of contents may have occurred. Serving scoop included. Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Glutamine by NutraBio Drug Interactions

Want to check YOUR meds against Glutamine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Glutamine interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

Glutamine by NutraBio: Common Questions

Does Glutamine by NutraBio interact with any medications?
Yes. Based on its ingredients, Glutamine has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glutamine safe to take while I'm pregnant or breastfeeding?
Glutamine is rated likely safe in pregnancy, so it's reasonable to discuss with your doctor. Breastfeeding is different — there isn't enough reliable safety data to recommend supplement doses while nursing unless your doctor advises it. Talk with your pharmacist or OB for personalized guidance.
What are the most common side effects?
Oral glutamine most often causes gastrointestinal effects: bloating, constipation, nausea, vomiting, diarrhea, and stomach pain. You might also notice belching, flatulence, headache, or cough. These tend to be mild, but high doses (10–30 grams daily) used in clinical trials increased the frequency of GI symptoms.
Can I take this if I have kidney or liver disease?
No — use it only under medical supervision if you have kidney or liver disease. Talk with your doctor before starting.
Will glutamine work for my condition?
Glutamine is effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness, the evidence is promising but still developing. Your doctor can tell you whether it's right for your situation.
What does glutamine actually do in your body?
Glutamine is an amino acid that supports immune function, gut health, and muscle metabolism. Your body makes it naturally, but supplemental doses may help in certain medical conditions — especially recovery from surgery or illness.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine label
Go deeper

The Full Monographs Behind Glutamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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