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Dietary supplement

Hemp Seed Oil Ingredients & Drug Interactions

by Country Farms

Hemp Seed Oil label
See full label image
Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hemp Seed Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hemp Seed Oil is a dietary supplement by Country Farms with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp Seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hemp Seed Oil by Country Farms

Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Seed Oil by Country Farms — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hemp Seed Oil by Country Farms

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hemp seed oil. Hemp seed is the whole seed from the Cannabis sativa plant—it's distinct from cannabis flower or extracts and contains little to no THC (the compound that gets you high).

The oil pressed from hemp seeds carries fatty acids and proteins that make up its composition.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hemp's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: heart healthy and supports hair skin nails.
  • We looked for evidence on: Hypertension, Atopic dermatitis (eczema), cardiovascular health, skin barrier function.
  • The closest evidence on file: Hemp is rated "Insufficient Reliable Evidence To Rate" for Atopic dermatitis (eczema) (Natural Medicines).
  • Also on file: Hemp is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

The evidence we hold for hemp seed oil doesn't establish it as effective for the conditions studied. For constipation, atopic dermatitis (eczema), and familial hypercholesterolemia (high cholesterol), the data rates as insufficient reliable evidence.

That means research is too limited or mixed right now to say whether it works for these purposes.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods and oils are generally well tolerated at normal food amounts. However, the safety data on concentrated supplements and extracts is much thinner, so caution is advised if you're using larger doses.

In rare cases, allergic reactions—including anaphylaxis, facial swelling, and breathing trouble—have been reported with hemp seed exposure. There's also a rare case report of liver enzyme elevation and hepatitis in a young child given high-dose hemp extract for seizures, though this involved much larger amounts and a different preparation than this oil.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take estrogen therapy or hormone replacement—hemp may interfere with how well it works. Also flag any blood pressure medications, blood thinners, or ACE inhibitors, where hemp could add to their effects.

If you take any prescription drug metabolized by the liver, mention this supplement when you check, since hemp may reduce how well some medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Hemp seed oil is generally well tolerated as a food supplement at normal doses, but it interacts with hormone therapy, blood pressure medications, blood thinners, and several drug-metabolizing pathways. If you take any prescription medications—especially birth control, estrogen replacement, blood pressure drugs, or blood thinners—talk with your doctor or pharmacist before starting this product.

Rare allergic reactions are possible, so stop and seek help if you notice hives, swelling, or breathing changes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hemp Seed Oil, straight from the product label.

Brand Country Farms
Barcode (UPC) 035046109806
Net contents 8 Fluid Ounce(s); 236 Milliliter(s)
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 259792
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hemp Seed Oil by Country Farms, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL
Maximum serving Sizes:
5 mL
Servings per container
47
UPC/BARCODE
035046109806
IngredientAmount% DV
Calories40 Calorie(s)--
Total Fat4.5 Gram(s)6%
Hemp Seed Oil4600 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Hemp seed oil benefits: Heart healthy Supports hair, skin & nails

Alcohol free Dairy & gluten free

100% cold pressed

THC free

100% tested

Formula

Paleo friendly

Essential fatty acids

Cannabis sativa oil

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Use one or more teaspoons daily added to your favorite food, shake, smoothie or enjoy alone.

Precautions

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in cool, dry place. Protect from heat, light, & moisture.

Brand IP Statement(s)

Country Farms Farm Fresh Est. 1975

General Statements

Facebook.com countryfarmfresh Instagram.com countryfarmfresh Please recycle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hemp Seed Oil by Country Farms label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hemp Seed Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hemp Seed Oil by Country Farms

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container47 Amounts shown are per serving.

Hemp Seed Oil

Interacts with
938 drugs
4600 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Hemp Seed Oil monograph & interactions
Interaction report

Hemp Seed Oil by Country Farms Drug Interactions

Want to check YOUR meds against Hemp Seed Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Hemp Seed Oil 938

Individual Drug Interactions

The ingredients in Hemp Seed Oil interact with 938 drugs. Click any drug to see the details.

1 of the 1 ingredient in Hemp Seed Oil interact with drugs. Each result below shows which ingredient is responsible. Hemp Seed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Hemp Seed Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hemp Seed Oil6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Hemp Seed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hemp Seed Oil, from the product label.

Country Farms

Name
Country Farms
Street Address
10 Henderson Drive
City
West Caldwell
State
NJ
ZipCode
07006
Web Address
CountryFarms.com
Pharmacist Counseling Corner

Hemp Seed Oil by Country Farms: Common Questions

Does Hemp Seed Oil by Country Farms interact with any medications?
Yes. Based on its ingredients, Hemp Seed Oil has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hemp Seed Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I'm on birth control or hormone replacement therapy?
Not without checking first. Hemp seed oil may interfere with estrogen-based hormone therapy because it can affect estradiol levels in your body. Talk with your doctor or pharmacist before starting—they can tell you if it's okay for your specific situation or if you need to adjust anything.
What are the side effects of hemp seed oil?
Most people tolerate it well, especially at food amounts. Rare allergic reactions have been reported—hives, facial swelling, shortness of breath, and anaphylaxis—though these are uncommon. There's also one old case report of liver problems in a very young child given extremely high doses of hemp extract, but that's not typical of hemp seed oil at normal doses.
Does hemp seed oil have THC in it?
No. Hemp seed oil is pressed from the seeds, not the flower, and seeds contain little to no THC. It won't get you high or show up on a drug test.
Is it safe to take during pregnancy or while breastfeeding?
We don't have safety data on file for hemp seed oil in pregnancy or lactation. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or breastfeeding—they can advise you based on your individual health.
Will this help with my high cholesterol or eczema?
The evidence we hold doesn't establish that it works for either. Research is too limited to say whether hemp seed oil helps with cholesterol or atopic dermatitis. If you're considering it for those reasons, discuss your options with your doctor first.
Can I take this with blood pressure medication or blood thinners?
Potentially, but not without checking. Hemp seed protein may add to blood pressure medication effects, and it might theoretically increase bleeding risk with blood thinners. Your doctor or pharmacist needs to know you're taking this if you're on any of those medications so they can monitor you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hemp Seed Oil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hemp Seed Oil label
Go deeper

The Full Monographs Behind Hemp Seed Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Hemp Seed Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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