Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Holy Basil Force Ingredients & Drug Interactions

by New Chapter

Holy Basil Force label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Holy Basil Force against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Holy Basil Force is a dietary supplement by New Chapter with 2 active ingredients. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Holy Basil Leaf Supercritical Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Holy Basil Force by New Chapter

Ask about any prescription or over-the-counter medication and we check it for interactions with Holy Basil Force by New Chapter — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Holy Basil Force by New Chapter

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Holy Basil Force contains 2 active ingredients: a supercritical extract and a hydroethanolic extract — both derived from holy basil leaf. These are different preparation methods of the same plant, designed to deliver its bioactive compounds.

The capsules also contain inactive ingredients (olive oil, a plant-based capsule material, and waxes) that help with delivery and stability.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Holy Basil product and its label doesn't state a use — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that holy basil is effective for any of the conditions it's marketed for — generalized anxiety disorder, asthma, headache, respiratory tract infections, dental plaque, or diabetes all carry a rating of insufficient reliable evidence to rate. That doesn't mean it doesn't work; it means the high-quality studies to prove it aren't available in our data yet.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil extract is generally well tolerated short-term in adults, but long-term safety data are limited. The most common side effects are loose stools and nausea — a small number of trial participants taking holy basil capsules experienced these.

The product is rated possibly unsafe in pregnancy and should be avoided — animal data raise concerns and human safety isn't established. Because there isn't enough reliable safety information, avoid it while breastfeeding too.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Holy Basil Force, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin), diabetes medications, or pentobarbital or other sedatives. Holy basil may increase bleeding risk with the first group, lower blood sugar too much with the second, and intensify sedation with the third.

None of these interactions have been proven in humans, but the animal evidence suggests caution.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a two-ingredient holy basil product with potential interactions involving blood thinners, diabetes drugs, and sedatives. Evidence for its effectiveness hasn't been established in our data.

It's generally well tolerated short-term, but it's not recommended during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's right for you and to check it against any medications you're taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holy Basil Force, straight from the product label.

Brand New Chapter
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 288204
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holy Basil Force by New Chapter, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
IngredientAmount% DV
Holy Basil Leaf Supercritical Extract268 mg--
Holy Basil Leaf Hydroethanolic Extract268 mg--

Other ingredients: extra virgin Olive Oil, Hypromellose, Yellow Beeswax, Candelilla Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: One capsule daily with food.

Precautions

Not recommended for use in children.

Caution: As with any dietary supplement, advise your healthcare professional of the use of this product if you have a medical condition or are taking medication. If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare professional prior to using this product.

Discontinue use and contact your healthcare professional if you experience a side effect or an allergic reaction.

Do not exceed suggested use.

Keep out of reach of children.

General Statements

Please refer to newchapter.com for more information about this product and its benefits.

The New Chapter money-back guarantee We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details.

Please recycle this bottle after use.

For questions or comments call 1-888-874-4461

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

2020 New Chapter, Inc. Est. 1982

Formula

Pure & potent extracts

Formulation

Stress relief, cognitive function, & immune support

Seals/Symbols

Non GMO Project Verified nongmoproject.org NSF Certified Gluten-free Certified B Corporation

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Holy Basil Force by New Chapter label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Holy Basil Force label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Holy Basil Force by New Chapter

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Holy Basil Leaf Supercritical Extract

Interacts with
212 drugs
268 mg per serving Form: Ocimum sanctum Leaf Supercritical Extract

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil Leaf Supercritical Extract monograph & interactions

Holy Basil Leaf Hydroethanolic Extract

Interacts with
212 drugs
268 mg per serving Form: Ocimum sanctum Leaf Hydroethanolic Extract

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil Leaf Hydroethanolic Extract monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil, Hypromellose, Yellow Beeswax, Candelilla Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holy Basil Force by New Chapter Drug Interactions

Want to check YOUR meds against Holy Basil Force?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Holy Basil Leaf Supercritical Extract 212

Individual Drug Interactions

The ingredients in Holy Basil Force interact with 212 drugs. Click any drug to see the details.

1 of the 2 ingredients in Holy Basil Force interact with drugs. Each result below shows which ingredient is responsible. Holy Basil Leaf Supercritical Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Holy Basil Force with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Holy Basil Leaf Supercritical Extract3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil Leaf Supercritical Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Holy Basil Force, from the product label.

New Chapter

See all New Chapter products
Name
New Chapter, Inc.
Street Address
90 Technology Drive
City
Brattleboro
State
VT
ZipCode
05301
Phone Number
888-874-4461
Web Address
www.newchapter.com/guarantee
Pharmacist Counseling Corner

Holy Basil Force by New Chapter: Common Questions

Does Holy Basil Force by New Chapter interact with any medications?
Yes. Based on its ingredients, Holy Basil Force has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Holy Basil Force contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or nursing?
No. The safety data advise against it during pregnancy — animal studies raise concerns and human safety isn't established. There also isn't enough reliable safety information for breastfeeding. Talk with your doctor if you're considering it during either period.
What are the side effects?
The most common are loose stools and nausea. Holy basil extract seems to be well tolerated overall, but a small number of people in clinical trials reported these digestive issues. Long-term safety data are limited.
Does this actually work for anxiety or diabetes?
We don't have reliable evidence that it does. The product is marketed for several conditions — anxiety, asthma, headache, respiratory infections, dental plaque, and diabetes — but the data on file doesn't establish effectiveness for any of them.
Why does this interact with so many medications?
The product lists 212 interacting medications because holy basil affects several broad drug categories — blood thinners, diabetes drugs, and sedatives. Each category includes many individual medications, which is why the number is high even though only three drug types are involved.
Is this product just one ingredient or two?
Two — a supercritical extract and a hydroethanolic extract, both from holy basil leaf. They're different ways of preparing the plant to pull out its active compounds. The capsule itself contains inert ingredients like olive oil and waxes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holy Basil Force label
Go deeper

The Full Monographs Behind Holy Basil Force’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Holy Basil Force's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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