Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Kosher Vivix Ingredients & Drug Interactions

by Shaklee

Kosher Vivix label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kosher Vivix against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kosher Vivix is a dietary supplement by Shaklee with 2 active ingredients. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Trans-Resveratrol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kosher Vivix by Shaklee

Ask about any prescription or over-the-counter medication and we check it for interactions with Kosher Vivix by Shaklee — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kosher Vivix by Shaklee

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Kosher Vivix is a liquid supplement with 2 active ingredients: trans-resveratrol and a Kosher Polyphenol Blend. The resveratrol is a compound found in grape skin and other plants, thought to have antioxidant properties.

The inactive ingredients — sorbitol, water, glycerin, natural flavors, and silicon dioxide — are fillers and flavorings that make up the rest of the formula.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Resveratrol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Cell defense and energy at cellular level.
  • We looked for evidence on: Cardiovascular disease (CVD), Diabetes, Metabolic syndrome, Hypercholesterolemia, Hypertension, Aging skin — and 3 related terms.
  • The closest evidence on file: Resveratrol is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Resveratrol is rated "Possibly Ineffective" for Hypercholesterolemia, Metabolic syndrome.
  • Also on file: Resveratrol is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Diabetes, Hypertension.

The data shows trans-resveratrol is possibly effective for obesity and allergic rhinitis (hay fever), but possibly ineffective for cardiovascular disease and high cholesterol. If you're considering this product for heart health or cholesterol, the evidence doesn't support that use based on what we have.

The evidence, ingredient by ingredient Resveratrol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Resveratrol is generally well tolerated at typical supplement doses. At higher doses, some people report diarrhea, loose stools, or gastrointestinal discomfort.

There's also an isolated report of a skin rash that cleared two weeks after stopping the supplement. The safety notes advise against use during pregnancy and breastfeeding because there isn't enough information to know it's safe in those situations.

Side effects, ingredient by ingredient Resveratrol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Resveratrol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 823 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you use blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel) — resveratrol may increase bleeding risk. Also flag any medications broken down by liver enzymes, especially CYP2C19, CYP1A2, CYP3A4, or CYP2E1 substrates — resveratrol may raise their levels in your blood.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Kosher Vivix may be worth considering if you're looking into supplements for obesity or seasonal allergies, though the evidence is modest. If you take any blood thinners, antiplatelet drugs, or medications broken down by your liver, you'll want to check with your doctor or pharmacist first — resveratrol may raise their levels or increase bleeding risk.

Talk it over with your healthcare provider before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kosher Vivix, straight from the product label.

Brand Shaklee
Net contents 5.1 fl. Oz.; 150 mL
Market status On market
Date entered into DSLD Jan 25, 2012
DSLD ID 5054
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kosher Vivix by Shaklee, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 tsp
Maximum serving Sizes:
1 tsp
Servings per container
30
IngredientAmount% DV
Calories15 {Calories}--
Total Carbohydrates4 g1%
Kosher Polyphenol Blend1290 mg--
Trans-Resveratrol100 mg--

Other ingredients: Sorbitol, Water, Glycerin, Natural flavors, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Just one teaspoon daily delivers a broad spectrum of beneficial polyphenols. These proprietary ingredients are proven to be 10X more powerful than resveratrol in slowing a key mechanism of aging at the cellular level. All natural.

NEW DRIP-PROOF CAP

Cell Defense. The ingredients in Kosher Vivix have been clinically proven to blunt the biological stress response, which can cause cellular aging.* Cell Energy. Proven in lab studies, Kosher Vivix ingredients increase energy production at the cellular level, which declines as we age.* Cell Repair. Proven in lab studies, Kosher Vivix ingredients protect and repair DNA, which is assaulted millions of times every day.* Cell Performance. Proven in lab studies, Kosher Vivix ingredients activate key genetic regulators that improve cellular performance.*

Clinically tested key ingredients. Exclusive to Shaklee. In laboratory study.

ITEM #22911 XP110A

FDA Statement of Identity

LIQUID DIETARY SUPPLEMENT

LIQUID DIETARY SUPPLEMENT

Seals/Symbols

{Image}(R) Shaklee(R)

K

NATURAL • SAFE 100% GUARANTEED SINCE 1956 Shaklee(R)

General

WF053A ITEM #22911

Brand IP Statement(s)

Patent pending.

Kosher Vivix(R) ingredients have been proven to SLOW AGING AT THE CELLULAR LEVEL(TM)* in four ways.

Kosher Vivix(R) is an all-natural, scientifically advanced liquid dietary supplement developed to SLOW AGING AT THE CELLULAR LEVEL(TM)*.

SLOW AGING AT THE CELLULAR LEVEL(TM)*

Suggested/Recommended/Usage/Directions

Directions: Shake well before use. Take 1 teaspoon daily with a meal.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Keep refrigerated.

Precautions

Caution: Not intended for use by children, or by pregnant or lactating women.

For your protection, this bottle has a tamper-evident seal over the closure.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kosher Vivix by Shaklee label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kosher Vivix label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kosher Vivix by Shaklee

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 tsp Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kosher Polyphenol Blend

1290 mg per serving Form: European Elderberry extract, European Elderberry juice powder, Pomegranate extract, Pomegranate juice concentrate

Trans-Resveratrol

Interacts with
822 drugs
100 mg per serving

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

Trans-Resveratrol monograph & interactions

Other (inactive) ingredients: Sorbitol, Water, Glycerin, Natural flavors, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kosher Vivix by Shaklee Drug Interactions

Want to check YOUR meds against Kosher Vivix?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
822Drugs
822 Moderate

Ingredients driving the most interactions

Trans-Resveratrol 822

Individual Drug Interactions

The ingredients in Kosher Vivix interact with 822 drugs. Click any drug to see the details.

1 of the 2 ingredients in Kosher Vivix interact with drugs. Each result below shows which ingredient is responsible. Trans-Resveratrol

Each ingredient & the kinds of drugs it affects

For each ingredient in Kosher Vivix with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Trans-Resveratrol5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
Trans-Resveratrol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kosher Vivix, from the product label.

Shaklee

See all Shaklee products
Name
SHAKLEE CORPORATION
Street Address
4747 WILLOW ROAD
City
PLEASANTON
State
CA
ZipCode
94588
Pharmacist Counseling Corner

Kosher Vivix by Shaklee: Common Questions

Does Kosher Vivix by Shaklee interact with any medications?
Yes. Based on its ingredients, Kosher Vivix has a known interaction with 822 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kosher Vivix contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant or breastfeeding?
There isn't enough safety information for concentrated resveratrol supplements during pregnancy or breastfeeding. Talk with your doctor or pharmacist before using this product in either situation — they can help you weigh the risks and benefits for your individual case.
What are the most common side effects?
The most common side effects are digestive — diarrhea, loose stools, and general stomach upset — usually when people take higher doses. These are generally mild, but if they bother you, let your doctor or pharmacist know.
Does this actually work for weight loss?
The data shows trans-resveratrol is possibly effective for obesity, but that's a modest rating — it's not a proven weight-loss supplement. Results, if any, are likely modest, and it should be paired with diet and exercise.
Can I take this if I have high cholesterol?
The evidence shows resveratrol is possibly ineffective for high cholesterol, so this supplement isn't supported for that use. If cholesterol is your concern, talk with your doctor about proven approaches.
What is the Kosher Polyphenol Blend in this product?
We don't have detailed information on that blend's composition or interactions — it's a proprietary mix in the formula. If you'd like specifics, contact Shaklee directly or ask your pharmacist to help you reach the company.
Can I take this with my other supplements?
We only have interaction data for the trans-resveratrol in this product. If you're taking other supplements or medications, bring a list to your pharmacist or doctor — they can check for interactions we may not have covered.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kosher Vivix label
Go deeper

The Full Monographs Behind Kosher Vivix’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Resveratrol

Interacts with 822 drugs

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...

Read the full Resveratrol monograph →
Sources

Sources & How We Checked

Kosher Vivix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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