Major interaction on record — check this product against your medications before combining. Based on 7 of 10 ingredients. Check your meds →
Dietary supplement

Lipo 6X Ingredients & Drug Interactions

by Nutrex Research

Lipo 6X label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lipo 6X against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Lipo 6X is a dietary supplement by Nutrex Research with 10 active ingredients. Its ingredients are commonly taken for mental alertness and reducing fatigue, improving athletic performance, headache and migraine relief.Based on those ingredients, 1,334 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Yohimbe, Synephrine, Caffeine Anhydrous. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lipo 6X by Nutrex Research

Ask about any prescription or over-the-counter medication and we check it for interactions with Lipo 6X by Nutrex Research — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lipo 6X by Nutrex Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 4 of its 10 active ingredients.
  • “Phase#1 Rapid Release Liquid Delivery Blend” is a proprietary blend — the label gives one combined amount (806 mg) without saying how much of each component you get.
  • “Synthetic Thermogenesis Activating Complex” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.

Lipo 6X contains 10 active ingredients designed to support weight loss and thermogenesis (heat production). The main players are caffeine anhydrous for mental alertness and energy, yohimbe (from yohimbe bark) and synephrine (from bitter orange) as stimulants, plus hordenine, tyramine, and B-phenylethylamine—all stimulant-type compounds.

It also contains glycerin (which may help with hydration and athletic performance), guggulsterones (resin extract), and proprietary blends labeled "Rapid Release Liquid Delivery" and "Thermogenesis Activating Complex" whose exact dosing is not disclosed. The capsules also hold a few inactive ingredients: polysorbate 80 (an emulsifier), vegetable cellulose (the capsule itself), and FD&C Blue #2 (food coloring).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: burn fat fast.
  • We looked for evidence on: Obesity, Athletic performance, Fatigue, Weight management, Metabolic rate, Energy expenditure.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Glycerol is rated "Possibly Effective" for Athletic performance.
  • Also on file: Caffeine is rated "Possibly Effective" for Obesity.

Evidence for Lipo 6X's ingredients is thin. Caffeine is likely effective for mental alertness and athletic performance, and glycerin is possibly effective for athletic performance.

Yohimbe, synephrine, hordenine, tyramine, and B-phenylethylamine all carry ratings of insufficient reliable evidence for weight loss, obesity, athletic performance, or any other health claim the product might suggest. The product label may claim these ingredients promote fat loss, but the science we hold doesn't back those claims.

The evidence, ingredient by ingredient Caffeine Yohimbe Bitter Orange Glycerol Hordenine Tyramine Phenethylamine (pea)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Caffeine is generally well tolerated in moderate amounts but high doses can cause serious side effects; common ones include anxiety, insomnia, jitteriness, headache, nausea, and diarrhea. Pregnancy safety is uncertain (possibly safe to possibly unsafe), and small amounts pass into breast milk.

Glycerin is generally well tolerated orally in normal amounts but can cause bloating, nausea, diarrhea, headache, and dizziness; large medicinal doses need doctor approval. Yohimbe and synephrine are the bigger safety concerns.

Yohimbe can cause serious heart and blood pressure effects and supplement potency is unpredictable; common effects include anxiety, agitation, tremors, hypertension, tachycardia, and nausea. It's unsafe in pregnancy and should be avoided while breastfeeding.

Synephrine (bitter orange) can raise blood pressure and heart rate, especially with caffeine; serious but rare effects include heart attack, QT prolongation, seizure, and stroke. Hordenine, tyramine, and B-phenylethylamine have very limited or no human safety data but may cause stimulant effects like rapid heartbeat and high blood pressure.

Tyramine is unsafe in supplement form due to lack of safety study, and B-phenylethylamine should be avoided in pregnancy and breastfeeding. N-methyl-beta-phenylethylamine, guggulsterones, and the proprietary blends have no safety data on file.

Side effects, ingredient by ingredient Caffeine Yohimbe Bitter Orange Glycerol Hordenine Tyramine Phenethylamine (pea)

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Yohimbe, Bitter Orange, Caffeine, Phenethylamine (pea), Hordenine, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,335 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Lipo 6X, double-check with your doctor or pharmacist if you take any of these medication types: monoamine oxidase inhibitors (MAOIs) like phenelzine—risk of dangerous blood pressure spike; blood pressure medications (antihypertensives)—this product may fight their effects; antidepressants, especially older tricyclics and any that boost serotonin—risk of serious interactions; antipsychotics like clozapine; anti-seizure drugs (phenobarbital, carbamazepine); heart medications including QT-prolonging drugs and dipyridamole; diabetes medications; quinolone antibiotics; cimetidine (heartburn); barbiturates like pentobarbital; dextromethorphan (cough suppressant); or any other stimulant. If you drink alcohol regularly, talk to your doctor too—tyramine's effects may be worsened.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Lipo 6X is a multi-ingredient stimulant product built around caffeine, yohimbe, and synephrine. If you take any blood pressure medication, antidepressant (especially MAOIs and tricyclics), anti-seizure drug, antipsychotic, or heart medication, you need to talk this over with your doctor or pharmacist before taking it—the interaction list is long and some are serious.

Even if you're not on medications, the combination of stimulants may cause rapid heartbeat, anxiety, or high blood pressure in some people, especially those with heart or blood pressure issues. Pregnancy and breastfeeding are not recommended due to insufficient safety data and stimulant effects.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lipo 6X, straight from the product label.

Brand Nutrex Research
Barcode (UPC) 853237000325
Net contents 120 Multi-Phase Capsule(s)
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 30142
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lipo 6X by Nutrex Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Multi-Phase Capsule(s)
Maximum serving Sizes:
2 Multi-Phase Capsule(s)
Servings per container
60
UPC/BARCODE
853237000325
IngredientAmount% DV
Glycerin0 Not Present--
Caffeine Anhydrous200 mg--
Yohimbe3 mg--
Synephrine20 mg--
Hordenine0 Not Present--
Tyramine0 Not Present--
B-Phenylethylamine0 Not Present--
N-Methyl-Beta-Phenylethylamine0 Not Present--
Synthetic Guggulsterones Z&E 1:120 mg--
Purified USP Water0 Not Present--
Phase#1 Rapid Release Liquid Delivery Blend806 mg--
Synthetic Thermogenesis Activating Complex100 mg--

Other ingredients: Polysorbate 80, Vegetable Cellulose, FD&C Blue #2

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

MULTI-PHASE Technology LIPO-6X is a powerful fat burner using a superior MULTI-PHASE technology. MULTI-PHASE technology combines rapid liquid capsule delivery with extended-release inside capsule technology. What this means is that LIPO-6X is a fat burner that has multiple release phases, both fast and extended.

LIPO-6X is best used in cycles. The suggested cycle length is 8 weeks followed by a 1 week break.

Actual capsules may differ in appearance from capsule shown on label.

Use your smart phone to scan this QR code and see real consumer reviews about this product. Or visit Nutrex.com

LIPO-6X offers speed and duration. A rapid onset of its fat-burning and energy-promoting effects, combined with an extended-release, will help ensure maximum results.

Phase #2 Extended-Release Inside Capsule: LIPO-6X continues to work over an extended period of time thanks to the slower release second capsule that sits inside the liquid capsule. Due to its delayed absorption the inside capsule extends the amount of time LIPO-6X is active.

MULTI-PHASE TECHNOLOGY

TWO-PHASE RELEASE BURN FAT FAST!

LIPO-6X is best used in cycles. The suggested cycle length is 8 weeks followed by a 1 week break.

Phase #1 Rapid Release Liquid Capsule: The outer liquid capsule of LIPO-6X ensures a rapid uptake of its appetite-suppressing, fat-burning and energy-promoting ingredients. Within minutes of taking LIPO-6 you will feel it working.

Precautions

Do not exceed recommended dosage. Do not consume synephrine, caffeine or thyroid-boosting compounds from other sources, including but not limited to, coffee, tea, soda and other dietary supplements or medications containing Phenylephrine or caffeine.

Do not consume synephrine, caffeine or thyroid-boosting compounds from other sources, including but not limited to, coffee, tea, soda and other dietary supplements or medications containing Phenylephrine or caffeine.

WARNING: LIPO-6X is not for use by persons under the age of 18.

Do not use if pregnant or nursing.

Consult your physician prior to use if you are taking medications, including but not limited to, MAOI inhibitors, anti-depressants, aspirin, non-steroidal anti-inflammatory drugs or products containing phenylephrine, ephedrine, pseudoephedrine, or other stimulants.

Consult your physician prior to use if you have a medical condition, including but not limited to heart, liver, kidney or thyroid disease, psychiatric disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate, or glaucoma. Discontinue 2 weeks prior to surgery. Immediately discontinue if you experience rapid heart beat, dizziness, severe headaches or shortness of breath.

This product contains ingredients that may be banned by some sports organizations.

KEEP OUT OF REACH OF CHILDREN.

Suggested/Recommended/Usage/Directions

RECOMMENDED USE TO BURN FAT FAST: Start off with only 2 multi-phase capsules on your first two days (1 in the morning and 1 in the afternoon) and increase dosage by 1 multi-phase capsule every two days until maximum dosage of 4 multi-phase capsules per day is reached. From here on take 2 multi-phase capsules in the morning and an additional 2 multi-phase capsules in the afternoon. DO NOT EXCEED 4 MULTI-PHASE CAPSULES PER DAY. Do not take within 6 hours of sleep.

For optimum results LIPO-6X should not be taken with meals. Consume at least 30 minutes before a meal.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose,treat, cure, or prevent any disease.

Formula

This product contains caffeine.

FDA Statement of Identity

Dietary Supplement

General

LBL-LIPO6X-120CT-V4-US

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lipo 6X by Nutrex Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lipo 6X label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lipo 6X by Nutrex Research

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Multi-Phase Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Caffeine Anhydrous

Interacts with
655 drugs
200 mg per serving

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredn...

Caffeine Anhydrous monograph & interactions

Yohimbe

Interacts with
1,125 drugs
3 mg per serving

Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription...

Yohimbe monograph & interactions

Synephrine

Interacts with
957 drugs
20 mg per serving

Bitter orange is a citrus fruit whose extracts contain synephrine, a mild stimulant often added to weight-loss and energy supplements. Evidence that i...

Synephrine monograph & interactions

Synthetic Guggulsterones Z&E 1:1

20 mg per serving

Phase#1 Rapid Release Liquid Delivery Blend

806 mg per serving

Synthetic Thermogenesis Activating Complex

100 mg per serving

Other (inactive) ingredients: Polysorbate 80, Vegetable Cellulose, FD&C Blue #2. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lipo 6X by Nutrex Research Drug Interactions

Want to check YOUR meds against Lipo 6X?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,334Drugs
190 Major 1,118 Moderate 26 Minor

Ingredients driving the most interactions

Yohimbe 1,125
Synephrine 957
Caffeine Anhydrous 655
Tyramine 353
Hordenine 329

Individual Drug Interactions

The ingredients in Lipo 6X interact with 1,334 drugs. Click any drug to see the details.

6 of the 10 ingredients in Lipo 6X interact with drugs. Each result below shows which ingredient is responsible. Yohimbe Synephrine Caffeine Anhydrous Tyramine Hordenine B-Phenylethylamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Lipo 6X with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Yohimbe13 drug types · 1,125 drugs

Monoamine Oxidase Inhibitors (Maois)

Concomitant use of MAOIs with yohimbe can result in additive effects.
Yohimbine, a constituent of yohimbe, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO.

Likelihood Likely Evidence D
Antihypertensive Drugs

Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Yohimbine, a constituent of yohimbe, is an alpha-2 adrenoceptor antagonist and has been reported to increase blood pressure in clinical research. Theoretically, concomitant use of yohimbe and antihypertensive drugs can interfere with blood pressure control.

Likelihood Probable Evidence D
Clonidine (Catapres)

Theoretically, yohimbe might precipitate clonidine withdrawal.
Chronic clonidine use can downregulate alpha-2 adrenoreceptors. Animal research and one human case report suggest that concomitant administration of yohimbine, an alpha-2 adrenoceptor antagonist, may precipitate clonidine withdrawal and lead to sympathomimetic toxicity, including hypertensive crisis.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Inhibitors

CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP2D6 isoenzymes. Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine and reduces the clearance of yohimbine compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers..

Likelihood Probable Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
In vitro research suggests that yohimbine, a constituent of yohimbe bark, inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Inhibitors

Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of yohimbine, a constituent of yohimbe bark.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP3A4 enzymes. Theoretically, drugs that inhibit CYP3A4 might increase the levels and adverse effects of yohimbine.

Likelihood Possible Evidence D
Paroxetine (Paxil)

Paroxetine decreases the clearance of yohimbine and may increase its effects.
Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine by about 350% and reduces the clearance of yohimbine by about 80% compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers. No significant changes in pharmacokinetic parameters of yohimbine were observed with coadministration of paroxetine in patients who are poor CYP2D6 metabolizers.

Likelihood Probable Evidence B
Phenothiazines

Theoretically, using yohimbine with phenothiazines might have additive effects.
Yohimbine, a constituent of yohimbe, has alpha-2 adrenergic antagonist effects. Theoretically, combining it with phenothiazines can cause additive alpha-2 adrenergic antagonism.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Yohimbine, a constituent of yohimbe, has sympathomimetic effects and increases blood pressure in a dose-dependent manner. Theoretically, taking yohimbe with stimulant drugs can have additive stimulant and hypertensive effects.

Likelihood Possible Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, taking yohimbe with TCAs can increase adverse effects.
A small clinical study in patients taking TCAs for at least 4 weeks shows that receiving doses of intravenous yohimbine 2.5-20 mg daily for up to 7 days precipitates severe anxiety, agitation, and tremor. The effects of yohimbe bark itself are unclear; oral yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical research.
Research in healthy adults shows that taking yohimbine, a constituent of yohimbe bark, in doses of 8 mg or more, seems to inhibit platelet aggregation in vitro by binding to the alpha-2 adrenoceptor. The effects of yohimbe bark itself are unclear; yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that yohimbe extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that yohimbe extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Yohimbe full monograph & interactions

Synephrine13 drug types · 957 drugs

Midazolam (Versed)

Bitter orange might increase blood levels of midazolam.
One small clinical study shows that bitter orange juice can increase midazolam levels, likely through inhibition of cytochrome P450 3A4 (CYP3A4). Theoretically, bitter orange might increase the risk of midazolam-related adverse effects.

Likelihood Probable Evidence B
Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking MAOIs with synephrine-containing bitter orange preparations might increase the hypertensive effects of synephrine, potentially leading to hypertensive crisis.
Bitter orange contains tyramine, octopamine, and synephrine, which are MAO substrates.

Likelihood Probable Evidence D
Antidiabetes Drugs

Theoretically, bitter orange might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that drinking a tea containing bitter orange and Indian snakeroot reduces fasting and postprandial glucose levels in patients with type 2 diabetes who are using antidiabetes drugs. However, it is unclear if these effects are due to bitter orange, Indian snakeroot, or the combination. An animal study also shows that p-synephrine in combination with gliclazide , a sulfonylurea, causes an additional 20% to 44% decrease in glucose levels when compared with gliclazide alone.

Likelihood Possible Evidence B
Caffeine

Bitter orange might increase blood pressure and heart rate when taken with caffeine.
Small clinical studies show that taking bitter orange in combination with caffeine can increase blood pressure and heart rate in otherwise healthy normotensive adults. Theoretically, this might increase the risk of serious cardiovascular adverse effects.

Likelihood Possible Evidence B
Colchicine

Bitter orange might affect colchicine levels.
Colchicine is a substrate of P-glycoprotein and cytochrome P450 3A4 (CYP3A4). Bitter orange has been reported to inhibit CYP3A4 and increase levels of CYP3A4 substrates. However, one small clinical study in healthy adults shows that drinking bitter orange juice 240 mL twice daily for 4 days and taking a single dose of colchicine 0.6 mg on the 4th day decreases colchicine peak serum levels by 24%, time to peak serum level by 1 hour, and overall exposure to colchicine by 20%. The clinical significance of this finding is unclear.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Bitter orange might increase levels of drugs metabolized by CYP3A4.
Small clinical studies suggest that single or multiple doses of freshly squeezed bitter orange juice 200-240 mL can inhibit CYP3A4 metabolism of drugs, causing increased drug levels and potentially increasing the risk of adverse effects. However, the extent of the effect of bitter orange on CYP3A4-mediated drug interactions is unknown. Some evidence suggests that bitter orange selectively inhibits intestinal CYP3A4, but not hepatic CYP3A4. Its effect on P-glycoprotein, which strongly overlaps with CYP3A4 interactions, is unclear. One small clinical study shows that drinking 8 ounces of freshly squeezed bitter orange juice has no effect on cyclosporine, which seems to be more dependent on hepatic CYP3A4 and P-glycoprotein than intestinal CYP3A4.

Likelihood Possible Evidence B
Dextromethorphan (Robitussin Dm, Others)

Bitter orange might increase blood levels of dextromethorphan.
One small clinical study shows that bitter orange juice increases dextromethorphan levels, likely through cytochrome P450 3A4 (CYP3A4) inhibition. Theoretically, bitter orange might increase the risk for dextromethorphan-related adverse effects.

Likelihood Possible Evidence B
Felodipine (Plendil)

Bitter orange might increase blood levels of felodipine.
One small clinical study shows that bitter orange juice increases felodipine levels, likely through cytochrome P450 3A4 (CYP3A4) inhibition. Theoretically, bitter orange might increase the risk for felodipine-related adverse effects.

Likelihood Probable Evidence B
Indinavir (Crixivan)

Bitter orange might increase blood levels of indinavir.
One small clinical study shows that bitter orange juice slightly increases indinavir levels, but this effect is likely to be clinically insignificant. Bitter orange selectively inhibits intestinal cytochrome P450 3A4 (CYP3A4); however, the metabolism of indinavir seems to be more dependent on hepatic CYP3A4. The effect of bitter orange on other protease inhibitors has not been studied.

Likelihood Possible Evidence B
Qt Interval-Prolonging Drugs

Theoretically, bitter orange might have an additive effect when combined with drugs that prolong the QT interval, potentially increasing the risk of ventricular arrhythmias.
One case report suggests that taking bitter orange in combination with other stimulants such as caffeine might prolong the QT interval in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Bitter orange juice might increase blood levels of sildenafil.
A small clinical study in healthy adult males shows that drinking freshly squeezed bitter orange juice 250 mL daily for 3 days and taking a single dose of sildenafil 50 mg on the 3rd day increases the peak plasma concentration of sildenafil by 18% and the overall exposure to sildenafil by 44%. Theoretically, this may be due to inhibition of cytochrome P450 3A4 by bitter orange.

Likelihood Probable Evidence B
Stimulant Drugs

Theoretically, bitter orange might increase the risk of hypertension and adverse cardiovascular effects when taken with stimulant drugs.
Bitter orange appears to have stimulant effects.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, bitter orange might increase levels of drug metabolized by CYP2D6.
In vitro research shows that octopamine, a constituent of bitter orange, weakly inhibits CYP2D6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Synephrine full monograph & interactions

Caffeine Anhydrous41 drug types · 655 drugs

Ephedrine

Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.

Likelihood Probable Evidence D
Adenosine (Adenocard)

Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Some evidence shows that caffeine is a competitive inhibitor of adenosine and can reduce the vasodilatory effects of adenosine in humans. However, other research shows that caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Possible Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Caffeine is reported to have antiplatelet activity. Theoretically, it might increase the risk of bleeding when used concomitantly with these agents; however, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Beta-Adrenergic Agonists

Theoretically, large amounts of caffeine might increase the cardiac inotropic effects of beta-agonists.

Likelihood Probable Evidence D
Carbamazepine (Tegretol)

Theoretically, caffeine might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.

Likelihood Possible Evidence D
Cimetidine (Tagamet)

Theoretically, cimetidine might increase the levels and adverse effects of caffeine.
Cimetidine decreases the rate of caffeine clearance by 31% to 42%.

Likelihood Likely Evidence B
Clozapine (Clozaril)

Caffeine might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Caffeine might increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Although researchers speculate that caffeine might inhibit CYP1A2, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to an interaction between clozapine and caffeine. In one case report, severe, life-threatening clozapine toxicity and multiorgan system failure occurred in a patient with schizophrenia stabilized on clozapine who consumed caffeine 600 mg daily.

Likelihood Possible Evidence B
Dipyridamole (Persantine)

Theoretically, caffeine might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Caffeine inhibits dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram use might increase the levels and adverse effects of caffeine.
Disulfiram decreases the rate of caffeine clearance.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Ethosuximide (Zarontin)

Theoretically, caffeine might reduce the effects of ethosuximide and increase the risk for convulsions.
Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Felbamate (Felbatol)

Theoretically, caffeine might reduce the effects of felbamate and increase the risk for convulsions.
Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Flutamide (Eulexin)

Theoretically, caffeine might increase the levels and adverse effects of flutamide.
In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.

Likelihood Probable Evidence D
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence D
Lithium

Abrupt caffeine withdrawal might increase the levels and adverse effects of lithium.
Caffeine has diuretic activity. When abruptly discontinued, caffeine may alter the clearance of lithium. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal and 6 case reports of elevated serum lithium levels after reducing or eliminating caffeine intake. In one case, a male with schizoaffective disorder stabilized on lithium had an elevated lithium level after reducing his caffeine intake by 87%. At a later date, he increased his caffeine intake by 6-fold, resulting in a subtherapeutic lithium level and a recurrence of psychiatric symptoms.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, caffeine might decrease the effects of pentobarbital.
Caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

Theoretically, caffeine might reduce the effects of phenobarbital and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, caffeine might reduce the effects of phenytoin and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Pioglitazone (Actos)

Theoretically, caffeine might increase the levels and clinical effects of pioglitazone.
Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Quinolones (also called fluoroquinolones) can decrease caffeine clearance by inhibiting cytochrome P450 1A2 (CYP1A2) enzyme.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.

Likelihood Possible Evidence D
Caffeine Anhydrous full monograph & all 41 interactions

Tyramine4 drug types · 353 drugs

Antihypertensive Drugs

Tyramine may increase the risk of hypertension and reduce the effects of antihypertensive drugs.
In humans, oral and intravenous tyramine increases systolic blood pressure.

Likelihood Likely Evidence B
Monoamine Oxidase Inhibitors (Maois)

Concomitant use of tyramine with MAOIs may increase the risk of serious adverse effects from tyramine.
Tyramine is metabolized by monoamine oxidase. Concurrent use of MAOIs with tyramine can lead to elevated levels of tyramine in the body. This can increase the effects of tyramine, which has been reported to cause hypertension, headache, and hypertensive crisis in numerous cases. Sensitivity to tyramine can increase up to 10-fold to 100-fold in people using an MAOI. The European Food Safety Authority states that meals containing more than 50 mg of tyramine might present a risk to patients that are using third generation MAOI medications. Meals containing more than 6 mg of tyramine are likely to present a risk to patients who are taking classic MAOI medications.

Likelihood Likely Evidence B
Alcohol

Theoretically, concomitant use of alcohol and tyramine might increase the risk of adverse effects from tyramine.
In vitro research suggests that alcohol may potentiate the toxic effects of biogenic amines, including tyramine, possibly by decreasing their breakdown.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, taking tyramine with stimulant drugs might increase the risk of adverse cardiovascular effects.
Tyramine is thought to have stimulant effects.

Likelihood Possible Evidence D
Tyramine full monograph & interactions

Hordenine3 drug types · 329 drugs

Monoamine Oxidase Inhibitors (Maois)

Hordenine is structurally similar to tyramine In vitro research shows that hordenine is a selective substrate for monoamine oxidase-B in the liver. Theoretically, concomitant use of hordenine with MAOIs might increase blood pressure, potentially leading to a hypertensive crisis.
Some MAOIs include isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate).

Likelihood Possible Evidence D
Stimulant Drugs

Hordenine is structurally similar to N-methyltyramine and synephrine, constituents in bitter orange known to have stimulant properties. Theoretically, taking hordenine with drugs with stimulant properties might increase the risk of hypertension and other adverse cardiovascular effects.
Some of these drugs include amphetamine, caffeine, methylphenidate, pseudoephedrine, and many others.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Hordenine weakly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro. Theoretically, hordenine might increase the levels of CYP2D6 substrates.
Some of drugs that are CYP2D6 substrates include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.

Likelihood Possible Evidence D
Hordenine full monograph & interactions

B-Phenylethylamine2 drug types · 187 drugs

Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking phenethylamine concomitantly with MAOIs may increase adverse effects.
In humans, phenethylamine is oxidized by MAO-B to form the inactive metabolite phenylacetic acid. Animal research shows that administering an MAOI prior to phenethylamine increases the amphetamine-like effects of phenethylamine. However, low-quality clinical research has used phenethylamine with selegiline, an MAOI, with apparent safety.

Likelihood Possible Evidence D
Serotonergic Drugs

Theoretically, combining serotonergic drugs with phenethylamine might increase the risk of serotonergic adverse effects.
Animal research shows that phenethylamine increases levels of serotonin, norepinephrine, and dopamine. Theoretically, combining serotonergic drugs with phenethylamine might increase the risk of additive serotonergic adverse effects, including serotonin syndrome and cerebral vasoconstrictive disorders. However, low-quality clinical research has used phenethylamine with selegiline, a monoamine oxidase inhibitor (MAOI), with apparent safety.

Likelihood Possible Evidence D
B-Phenylethylamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lipo 6X, from the product label.

Nutrex Research

See all Nutrex Research products
Name
Nutrex Research, Inc.
City
Oviedo
State
FL
ZipCode
32765
Phone Number
1-888-362-8739
Web Address
Nutrex.com
Pharmacist Counseling Corner

Lipo 6X by Nutrex Research: Common Questions

Does Lipo 6X by Nutrex Research interact with any medications?
Yes. Based on its ingredients, Lipo 6X has a known interaction with 1,334 medications, including 190 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lipo 6X contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does this product actually do?
Lipo 6X is designed as a thermogenic fat-loss supplement—it contains multiple stimulants meant to boost energy, alertness, and calorie burn. Caffeine is proven effective for alertness and athletic performance; the other ingredients (yohimbe, synephrine, hordenine, tyramine, phenethylamine) lack solid evidence for weight loss in humans, though they're meant to provide stimulant effects.
Is it safe to take with my blood pressure medication?
No—not without checking with your doctor first. Yohimbe, synephrine, caffeine, hordenine, and tyramine all can raise blood pressure or interfere with blood pressure control. Your doctor needs to know you're considering this before you start it.
What are the most common side effects?
From caffeine: anxiety, insomnia, jitteriness, headache, nausea, diarrhea, tremors. From yohimbe and synephrine: anxiety, agitation, tremors, rapid heartbeat, high blood pressure, nausea, dizziness. Your individual response depends on dose, sensitivity, and what else you're taking.
Can I take this if I'm pregnant or breastfeeding?
Caffeine is possibly safe in pregnancy at low doses but possibly unsafe at high doses—talk to your doctor about a safe limit. Yohimbe is unsafe in pregnancy and should be avoided while breastfeeding. Synephrine is possibly unsafe in pregnancy. Hordenine, tyramine, and phenethylamine have no safety data and should be avoided. Overall, this is not recommended during pregnancy or breastfeeding—check with your doctor first.
What if I take an antidepressant?
This depends on which one. If you take an MAOI (older drugs like phenelzine), you must not use Lipo 6X without your doctor's approval—the risk of dangerous blood pressure spike is high. Tricyclic antidepressants (like amitriptyline) also carry serious risks with yohimbe. SSRIs and other newer antidepressants may interact through phenethylamine's serotonin effects. Check with your doctor or pharmacist before taking it.
Why does this product have so many interactions?
It's a blend of six different stimulant-type compounds—caffeine, yohimbe, synephrine, hordenine, tyramine, and phenethylamine. Each one affects your heart rate, blood pressure, and how your liver breaks down drugs. Together, they multiply the chances of interacting with medications that manage blood pressure, mood, heart rhythm, blood sugar, seizures, and many other things.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lipo 6X is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lipo 6X label
Go deeper

The Full Monographs Behind Lipo 6X’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Caffeine

Interacts with 655 drugs

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...

Read the full Caffeine monograph → Herb & supplement monograph

Yohimbe

Interacts with 1,125 drugs

Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription form of yohimbine has some evidence for...

Read the full Yohimbe monograph → Herb & supplement monograph

Bitter Orange

Interacts with 957 drugs

Bitter orange is a citrus fruit whose extracts contain synephrine, a mild stimulant often added to weight-loss and energy supplements. Evidence that it works for weight loss or performance i...

Read the full Bitter Orange monograph → Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph → Herb & supplement monograph

Hordenine

Interacts with 329 drugs

Hordenine is a natural alkaloid found in barley and some cacti that is marketed as a stimulant for energy, focus, and fat loss, but solid human evidence for these benefits is lacking. Its sa...

Read the full Hordenine monograph → Herb & supplement monograph

Tyramine

Interacts with 353 drugs

Tyramine is a natural compound formed when certain proteins break down, and it is found in aged cheeses, cured meats, fermented foods, and some other items. It is not a typical health supple...

Read the full Tyramine monograph → Herb & supplement monograph

Phenethylamine (pea)

Interacts with 187 drugs

Phenethylamine (PEA) is a natural compound made in the body and found in foods like chocolate; supplements are marketed for mood, focus, and energy. Reliable human research on the supplement...

Read the full Phenethylamine (pea) monograph →
Sources

Sources & How We Checked

Lipo 6X's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 384 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Caffeine 236 references
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  47. Sanderink GJ, Bournique B, Stevens J, et al. Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro. Pharmacol Exp Ther 1997;282:1465-72. DOI
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  49. Carrillo JA, Benitez J. Clinically significant pharmacokinetic interactions between dietary caffeine and medications. Clin Pharmacokinet 2000;39:127-53. PubMed
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  56. Juliano LM, Griffiths RR. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features. Psychopharmacology (Berl) 2004;176:1-29. PubMed
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See these in context on the Bitter Orange monograph →

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See these in context on the Hordenine monograph →

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See these in context on the Tyramine monograph →

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See these in context on the Phenethylamine (pea) monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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