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Dietary supplement

Manganeses Amino Acid Chelate 10 mg Ingredients & Drug Interactions

by Source Naturals

Manganeses Amino Acid Chelate 10 mg label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Manganeses Amino Acid Chelate 10 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Manganeses Amino Acid Chelate 10 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for bone health support, antioxidant and enzyme support, filling dietary gaps.Based on those ingredients, 83 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Manganese. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Manganeses Amino Acid Chelate 10 mg by Source Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Manganeses Amino Acid Chelate 10 mg by Source Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Manganeses Amino Acid Chelate 10 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: 10 mg of manganese in a chelated form, which means the manganese is bound to amino acids to help your body absorb it more easily. The tablet also contains several inactive ingredients—sorbitol, stearic acid, silica, modified cellulose gum, and magnesium stearate—which are fillers and binders that hold the tablet together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports energy production.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Manganese is established as effective for treating manganese deficiency. For other uses listed on the label—hay fever, osteoporosis, COPD, weight loss, and osteoarthritis—the evidence isn't strong enough yet to rate them reliably, according to the data we hold.

If you're considering this supplement for one of those conditions, talk it over with your doctor or pharmacist about whether there's a better-studied option.

The evidence, ingredient by ingredient Manganese

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Manganese at normal dietary amounts is generally well tolerated. However, high-dose supplements can be harmful—there's a rare risk of neurotoxicity (nerve damage) with long-term high doses, including symptoms similar to Parkinson's disease.

One severe case involved someone taking 100 mg daily for 2 to 4 years. High doses can also damage the liver.

Because of this, avoid taking extra high-dose manganese supplements unless your doctor specifically advises it. For pregnancy, normal dietary amounts are fine, but avoid high-dose supplements without medical guidance.

For breastfeeding, data shows mixed safety signals—talk with your pharmacist or doctor about whether this dose is right for you.

Side effects, ingredient by ingredient Manganese

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Manganese.
  • The most serious interaction on file is rated Moderate.
  • For scale: 83 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your own pharmacist or doctor if you take any antipsychotic medications (like haloperidol), quinolone antibiotics (like ciprofloxacin or levofloxacin), or tetracycline antibiotics (like doxycycline or minocycline). Manganese may reduce how well these antibiotics work or increase risk with antipsychotics.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is useful if you have a manganese deficiency and your doctor recommends it. If you take antipsychotics or certain antibiotics, check with your own pharmacist or doctor before starting—the interactions could affect how well your medications work or how your body tolerates them.

Stick to the labeled dose and don't take extra-high amounts unless told to do so by a clinician.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Manganeses Amino Acid Chelate 10 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078003427
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 295984
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Manganeses Amino Acid Chelate 10 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
UPC/BARCODE
021078003427
IngredientAmount% DV
Manganese10 mg500%

Other ingredients: Sorbitol, Stearic Acid, Silica, modified Cellulose Gum, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formulation

Amino Acid Chelate Supports Energy Production

Suitable for vegetarians.

Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, salt, preservatives, or artificial color, flavor or fragrance.

Formula

Manganese is an essential trace mineral involved in many key functions in the body. It plays a role in energy production, in normal bone formation and development, and in the synthesis of many vital cellular biochemicals such as collagen, prothrombin, urea, mucopolysaccharides, fatty acids and proteins. In addition, manganese is a cofactor for superoxide dismutase, one of the body's main protective antioxidant systems. This manganese is specially bonded (chelated) with amino acids to protect mineral value and enhance assimilation.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 tablet daily.

Precautions

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright Source Naturals, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Manganeses Amino Acid Chelate 10 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Manganeses Amino Acid Chelate 10 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Manganeses Amino Acid Chelate 10 mg by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.

Manganese

Interacts with
83 drugs
10 mg per serving Form: Manganese Amino Acid Chelate

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Other (inactive) ingredients: Sorbitol, Stearic Acid, Silica, Modified Cellulose Gum, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Manganeses Amino Acid Chelate 10 mg by Source Naturals Drug Interactions

Want to check YOUR meds against Manganeses Amino Acid Chelate 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
83Drugs
83 Moderate

Ingredients driving the most interactions

Manganese 83

Individual Drug Interactions

The ingredients in Manganeses Amino Acid Chelate 10 mg interact with 83 drugs. Click any drug to see the details.

1 of the 1 ingredient in Manganeses Amino Acid Chelate 10 mg interact with drugs. Each result below shows which ingredient is responsible. Manganese

Each ingredient & the kinds of drugs it affects

For each ingredient in Manganeses Amino Acid Chelate 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Manganese full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Manganeses Amino Acid Chelate 10 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Manganeses Amino Acid Chelate 10 mg by Source Naturals: Common Questions

Does Manganeses Amino Acid Chelate 10 mg by Source Naturals interact with any medications?
Yes. Based on its ingredients, Manganeses Amino Acid Chelate 10 mg has a known interaction with 83 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Manganeses Amino Acid Chelate 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is manganese safe to take while breastfeeding?
The data on this product shows mixed safety signals for breastfeeding—some entries say possibly unsafe or likely unsafe. Talk with your own pharmacist or doctor about whether this supplement is right for you during breastfeeding.
What is manganese actually used for in the body?
Manganese is a mineral your body needs in small amounts. This product is proven effective for treating manganese deficiency—a condition your doctor can diagnose through blood tests—but evidence for other claimed uses like bone health isn't solid enough yet.
Can manganese cause side effects?
At the dose in this product (10 mg), side effects are rare. But high doses taken over time can cause serious nerve damage similar to Parkinson's disease and liver damage. Stick to the labeled dose unless your doctor tells you otherwise.
Why does the label mention so many health conditions if manganese only treats deficiency?
Manufacturers often list conditions people wonder about, but that doesn't mean the evidence supports using manganese for them. For hay fever, osteoporosis, COPD, weight, and joint pain, the evidence we have isn't strong enough to rate these uses reliably.
Should I take this supplement with food?
The product facts don't include guidance on timing or food. Ask your pharmacist whether taking it with or without food matters for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Manganeses Amino Acid Chelate 10 mg label
Go deeper

The Full Monographs Behind Manganeses Amino Acid Chelate 10 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Manganese

Interacts with 83 drugs

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get enough from a normal diet. Supplements m...

Read the full Manganese monograph →
Sources

Sources & How We Checked

Manganeses Amino Acid Chelate 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Manganese 21 references
  1. Hansten PD, Horn JR. Hansten and Horn's Drug Interactions Analysis and Management. Vancouver, CAN:Appl Therapeut, 1999.
  2. Barrington WW, Angle CR, Willcockson NK, et al. Autonomic function in manganese alloy workers. Environ Res 1998;78:50-8. PubMed
  3. Hauser RA, Zesiewicz TA, Martinez C, et al. Blood manganese correlates with brain magnetic resonance imaging changes in patients with liver disease. Can J Neurol Sci 1996;23:95-8. PubMed
  4. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  5. Lee JW. Manganese intoxication. Arch Neurol 2000;57:597-9.. PubMed
  6. Powers KM, Smith-Weller T, Franklin GM, et al. Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes. Neurology 2003;60:1761-6.. PubMed
  7. McMillan, D. E. A brief history of the neurobehavioral toxicity of manganese: some unanswered questions. Neurotoxicology 1999;20(2-3):499-507.
  8. Gerber, G. B., Leonard, A., and Hantson, P. Carcinogenicity, mutagenicity and teratogenicity of manganese compounds. Crit Rev Oncol Hematol. 2002;42(1):25-34. PubMed
  9. Jiang, Y. and Zheng, W. Cardiovascular toxicities upon manganese exposure. Cardiovasc.Toxicol 2005;5(4):345-354. PubMed
  10. Mehta, R. and Reilly, J. J. Manganese levels in a jaundiced long-term total parenteral nutrition patient: potentiation of haloperidol toxicity? Case report and literature review. JPEN J Parenter.Enteral Nutr 1990;14(4):428-430. PubMed
  11. Nemery, B. Metal toxicity and the respiratory tract. Eur Respir.J 1990;3(2):202-219. DOI
  12. Vanek VW, Borum P, Buchman A, et al. A.S.P.E.N. position paper: recommendations for changes in commercially available parenteral multivitamin and multi-trace element products. Nutr Clin Pract. 2012;27:440-491.doi: 10.1177/0884533612446706 PubMed
  13. Schuh MJ. Possible Parkinson's disease induced by chronic manganese supplement ingestion. Consult Pharm. 2016;31(12):698-703. doi: 10.4140/TCP.n.2016.698. PubMed
  14. Baker B, Ali A, Isenring L. Recommendations for manganese supplementation to adult patients receiving long-term home parenteral nutrition: an analysis of the supporting evidence. Nutr Clin Pract 2016;31(2):180-5. doi: 10.1177/0884533615591600. PubMed
  15. Ho CSH, Ho RCM, Quek AML. Chronic manganese toxicity associated with voltage-gated potassium channel complex antibodies in a relapsing neuropsychiatric disorder. Int J Environ Res Public Health 2018;15(4). pii: E783. doi: 10.3390/ijerph15040783. PubMed
  16. Yamamoto M, Sakurai K, Eguchi A, et al.; Japan Environment and Children's Study Group: Association between blood manganese level during pregnancy and birth size: the Japan environment and children's study (JECS). Environ Res 2019;172:117-26. PubMed
  17. Li D, Ge X, Liu Z, et al. Association between long-term occupational manganese exposure and bone quality among retired workers. Environ Sci Pollut Res Int 2020;27(1):482-9. PubMed
  18. Martin KV, Sucharew H, Dietrich KN, et al. Co-exposure to manganese and lead and pediatric neurocognition in East Liverpool, Ohio. Environ Res 2021;202:111644. PubMed
  19. Racette BA, Nelson G, Dlamini WW, et al. Depression and anxiety in a manganese-exposed community. Neurotoxicology 2021;85:222-33. PubMed
  20. Ruiz-Azcona L, Fernández-Olmo I, Expósito A, et al. Impact of environmental airborne manganese exposure on cognitive and motor functions in adults: a systematic review and meta-analysis. Int J Environ Res Public Health 2021;18(8):4075. PubMed
  21. Uyar E, Gurkas E, Aksu AU, et al. Can therapeutic plasma exchange be life-saving in life-threatening manganese intoxication?. Transfus Apher Sci 2022;61(4):103417. PubMed

See these in context on the Manganese monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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