Mind Soother Lavender Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Mind Soother Lavender against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mind Soother Lavender is a dietary supplement by Herb Pharm with 6 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation and calming.Based on those ingredients, 1,279 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Kava Rhizome, Root Extract, Bacopa Aerial Parts Extract, Passionflower Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mind Soother Lavender by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Mind Soother Lavender by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mind Soother Lavender by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Mind Soother Lavender contains 6 active ingredients: Albizia Bark Extract, Lavender Flower Extract, Kava Rhizome and Root Extract, Bacopa Aerial Parts Extract, Passion Flower Aerial Parts Extract, and Lavender Essential Oil. These are combined in a proprietary extract blend and delivered in liquid form with inactive ingredients including cane alcohol, distilled water, and glycerin.
Does it work?
Moderate evidence
The effectiveness data we hold shows mixed evidence. Lavender is rated Possibly Effective for dysmenorrhea (menstrual pain) but Possibly Ineffective for cancer-related pain; evidence is insufficient for alopecia areata, pre-procedural anxiety, and cancer-related fatigue.
Passion Flower is rated Possibly Effective for insomnia and pre-procedural anxiety. For the other active ingredients — Kava, Bacopa, and Albizia — the evidence we have is insufficient to rate their effectiveness for any condition, or no effectiveness data is on file.
How safe is it?
Well-documented data
Lavender is generally well tolerated orally and topically, though the essential oil is toxic if swallowed and can irritate skin in sensitive people. Common side effects from oral use include breath odor, constipation, diarrhea, upset stomach, and headache.
Kava is generally well tolerated but carries a rare risk of serious liver injury; over 100 cases of liver damage have been reported, especially with long-term use. Common side effects include drowsiness, dry mouth, dizziness, headache, and tremor.
Bacopa is generally well tolerated but may cause gastrointestinal upset, headache, drowsiness, or vivid dreams in some people. Passion Flower is well tolerated short-term but can cause confusion, dizziness, and drowsiness.
Pregnancy and breastfeeding: Safety data is insufficient for all ingredients. Kava specifically is rated possibly unsafe during pregnancy and should be avoided; it's also possibly unsafe while breastfeeding.
Meds to double-check
Major interaction found
Before starting Mind Soother Lavender, check with your pharmacist if you're taking CNS depressants (sleep aids, sedatives, anti-anxiety medications, opioids, alcohol) — this is the most serious concern and applies to multiple ingredients. Also check if you're on medications metabolized by liver enzymes, hepatotoxic drugs, haloperidol, ropinirole, anticholinergic medications, cholinergic drugs, thyroid hormone, or cevimeline.
No interactions are documented in our data for Albizia Bark Extract.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This is a multi-ingredient herbal blend that works best for people without sedative prescriptions or liver concerns. The biggest risk is combining it with medications that depress the central nervous system — even if you're not on one now, check any new prescriptions before adding this.
If you're pregnant, planning to be, or breastfeeding, talk to your pharmacist or doctor first; Kava especially should be avoided. Use the interaction checker below with your exact medication list.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mind Soother Lavender, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700004576 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 334496 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mind Soother Lavender by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 625 mg | -- |
| Albizia Bark Extract | 0 NP | -- |
| Lavender Flower Extract | 0 NP | -- |
| Kava Rhizome, Root Extract | 0 NP | -- |
| Bacopa Aerial Parts Extract | 0 NP | -- |
| Passionflower Aerial Parts Extract | 0 NP | -- |
| Lavender Essential Oil | 0 NP | -- |
Other ingredients: Cane Alcohol, Water, Distilled, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using. Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Caution: FDA advises that a potential risk of rare, but severe, liver injury may be associated with Kava. Stop use and see a doctor if liver symptoms occur (unusual fatigue, abdominal pain, appetite loss, dark urine, pale stools, yellow eyes or skin). Do not take with alcoholic beverages. Excessive use may briefly impair ability to drive or operate machinery.
Ask a healthcare professional before use if you have, or have had, liver problems, frequently use alcoholic beverages, or are taking any medication. Not for use by persons under 18 years of age, or by pregnant or breastfeeding women.
Not for use by persons under 18 years of age, or by pregnant or breastfeeding women. Keep Out of the Reach of Children
Storage
Store away from heat & light
Formulation
Nervous system
Gluten free
FDA Statement of Identity
Herbal Supplement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mind Soother Lavender by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mind Soother Lavender by Herb Pharm
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Albizia Bark Extract
- › Lavender Flower Extract
- › Kava Rhizome, Root Extract
- › Bacopa Aerial Parts Extract
- › Passionflower Aerial Parts Extract
- › Lavender Essential Oil
Other (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.
Mind Soother Lavender by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Mind Soother Lavender by Herb Pharm contains several ingredients with documented interactions, most notably kava.
Kava has a Major interaction with CNS depressants (sedatives, sleeping pills, anti-anxiety medications) — combining them increases drowsiness and impairs motor reflexes.
Read the full breakdown — every affected drug type, severity by severity
Lavender Flower Extract and Lavender Essential Oil both have Moderate interactions with CNS depressants, with similar additive sedative effects. Kava also interacts at Moderate severity with medications metabolized by liver enzymes CYP2C19, CYP2C9, CYP2E1, and CYP3A4; with hepatotoxic (liver-damaging) drugs; with P-glycoprotein substrates; and with the specific medications haloperidol and ropinirole.
Bacopa Aerial Parts Extract has Moderate interactions with CYP1A2, CYP2C19, CYP2C9, and CYP3A4 substrates, as well as with anticholinergic drugs, cholinergic drugs, cevimeline, and Minor interaction with thyroid hormone. Passion Flower has Moderate interaction with CNS depressants and Minor interactions with OATP and CYP3A4 substrates.
We could not check Albizia Bark Extract — no interaction data is on file for it.
Altogether, these interactions span 1,258 individual medications. Use the medication checker on this page to verify your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mind Soother Lavender?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mind Soother Lavender interact with 1,279 drugs. Click any drug to see the details.
4 of the 6 ingredients in Mind Soother Lavender interact with drugs. Each result below shows which ingredient is responsible. Kava Rhizome, Root Extract Bacopa Aerial Parts Extract Passionflower Aerial Parts Extract Lavender Flower Extract
AmitriptylineElavil
How Amitriptyline interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +4 Major
Interaction Summary
It is unclear if kava inhibits CYP3AA; research is conflicting.
Read the full Kava Rhizome, Root Extract + Amitriptyline interactionBacopa Aerial Parts ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +3 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Bacopa Aerial Parts Extract + Amitriptyline interactionPassionflower Aerial Parts ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Amitriptyline interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants +4 Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Amitriptyline, Chlordiazepoxide interactionPassionflower Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Parts Extract + Amitriptyline, Chlordiazepoxide interactionBacopa Aerial Parts ExtractAnticholinergic Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates +3 Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Amitriptyline, Chlordiazepoxide interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +4 Major
Interaction Summary
It is unclear if kava inhibits CYP3AA; research is conflicting.
Read the full Kava Rhizome, Root Extract + Amitriptyline, Perphenazine interactionPassionflower Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Parts Extract + Amitriptyline, Perphenazine interactionBacopa Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +3 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Aerial Parts Extract + Amitriptyline, Perphenazine interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Amitriptyline, Perphenazine interactionAmobarbitalAmytal
How Amobarbital interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Amobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Amobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Amobarbital, Ephedrine Sulfate interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Amobarbital, Ephedrine Sulfate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Amobarbital, Secobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Amobarbital, Secobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aprobarbital, Butabarbital, Phenobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aprobarbital, Butabarbital, Phenobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aprobarbital, Butabarbital, Phenobarbital interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Major
Interaction Summary
It is unclear if kava inhibits CYP3AA; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aripiprazole interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aripiprazole interactionBacopa Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Aerial Parts Extract + Aripiprazole interactionPassionflower Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Parts Extract + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aripiprazole Lauroxil interactionPassionflower Aerial Parts ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aripiprazole Lauroxil interactionBacopa Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Aerial Parts Extract + Aripiprazole Lauroxil interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aripiprazole Lauroxil interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionBacopa Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionPassionflower Aerial Parts ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aspirin, Caffeine, Codeine Phosphate interactionBacopa Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Caffeine, Codeine Phosphate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Caffeine, Codeine Phosphate interactionPassionflower Aerial Parts ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Major
Interaction Summary
It is unclear if kava inhibits CYP3AA; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPassionflower Aerial Parts ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBacopa Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Caffeine, Hydrocodone interactionBacopa Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Caffeine, Hydrocodone interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Caffeine, Hydrocodone interactionPassionflower Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Parts Extract + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants +3 Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionBacopa Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionPassionflower Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Parts Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionBacopa Aerial Parts ExtractCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aspirin, Codeine Phosphate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Codeine Phosphate interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Codeine Phosphate, Methocarbamol interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Codeine Phosphate, Methocarbamol interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Codeine Phosphate, Phenobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Codeine Phosphate, Phenobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Diphenhydramine, Phenylpropanolamine interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Ethoheptazine, Meprobamate interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Ethoheptazine, Meprobamate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants +1 Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aspirin, Hydrocodone interactionPassionflower Aerial Parts ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Hydrocodone interactionBacopa Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Hydrocodone interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Hydrocodone interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Aspirin, Oxycodone interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Oxycodone interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Aspirin, Pentazocine interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Aspirin, Pentazocine interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Aspirin, Pentazocine interactionBacopa Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Aerial Parts Extract + Aspirin, Pentazocine interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Atropine, Hyoscyamine, Phenobarbital interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Atropine, Hyoscyamine, Phenobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Atropine, Hyoscyamine, Phenobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Atropine, Phenobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Atropine, Phenobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Atropine, Phenobarbital interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants Major
Interaction Summary
It is unclear if kava inhibits CYP1A2; research is conflicting.
Read the full Kava Rhizome, Root Extract + Atropine, Meperidine interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Atropine, Meperidine interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Atropine, Meperidine interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Mind Soother Lavender — through 4 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Atropine, Morphine Sulfate interactionBacopa Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Aerial Parts Extract + Atropine, Morphine Sulfate interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Atropine, Morphine Sulfate interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Atropine, Morphine Sulfate interactionBelladona Extract, PhenobarbitalChardonna-2
How Belladona Extract, Phenobarbital interacts with Mind Soother Lavender — through 3 ingredients. Tap an ingredient for the detail:
Kava Rhizome, Root ExtractCns Depressants Major
Interaction Summary
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava Rhizome, Root Extract + Belladona Extract, Phenobarbital interactionLavender Essential OilCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender Essential Oil + Belladona Extract, Phenobarbital interactionPassionflower Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Parts Extract + Belladona Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mind Soother Lavender with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Kava Rhizome, Root Extract
Cns Depressants
Combining kava with CNS depressants can have additive sedative effects.
Kava has CNS depressant effects. Concomitant use of kava with other CNS depressants can increase the risk of drowsiness and motor reflex depression. Clinical practice guidelines from a joint taskforce of the World Federation of Societies of Biological Psychiatry (WFSBP) and the Canadian Network for Mood and Anxiety Treatments (CANMAT) recommend that CNS depressants, including alcohol and benzodiazepines, not be used with kava.
Alcohol (Ethanol)
Combining kava with alcohol may increase the risk of sedation and/or hepatotoxicity.
Kava has CNS depressant effects. Concomitant use of kava with other CNS depressants can increase the risk of drowsiness and motor reflex depression. Additionally, kava has been associated with over 100 cases of hepatotoxicity. There is some concern that kava can adversely affect the liver, especially when used in combination with hepatotoxic drugs. Clinical practice guidelines from a joint taskforce of the World Federation of Societies of Biological Psychiatry (WFSBP) and the Canadian Network for Mood and Anxiety Treatments (CANMAT) recommend that alcohol not be used with kava.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, kava might increase levels of CYP2C19 substrates.
In vitro research shows that kava significantly inhibits CYP2C19 enzymes. This effect has not yet been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, kava might increase levels of CYP2C9 substrates.
In vitro research shows that kava significantly inhibits CYP2C9 enzymes. This effect has not yet been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Kava might increase levels of CYP2E1 substrates.
In a clinical study in healthy volunteers, taking kava 1000 mg twice daily (containing a daily dose of 138 mg kavalactones) for 28 days inhibited the metabolism of CYP2E1 substrates.
Haloperidol (Haldol)
Combining kava and haloperidol might increase the risk of cardiovascular adverse effects and hypoxia.
Atrial flutter and hypoxia has been reported for a patient who received intramuscular injections of haloperidol and lorazepam after using kava orally. The side effects were attributed to kava-induced inhibition of CYP2D6, but might also have been related to additive adverse effects with the concomitant use of haloperidol, lorazepam, and kava.
Hepatotoxic Drugs
Theoretically, using kava with hepatotoxic drugs might increase the risk of liver damage.
Kava has been linked with over 100 cases of hepatotoxicity. Most cases occur with excessive and prolonged use. There is some concern that kava can adversely affect the liver, especially when used in combination with hepatotoxic drugs.
P-Glycoprotein Substrates
It is unclear if kava inhibits P-glycoprotein (P-gp); research is conflicting.
In vitro research shows that kava can inhibit P-gp efflux. However, a clinical study in healthy volunteers shows that taking kava standardized to provide 225 mg kavalactones daily for 14 days does not affect the pharmacokinetics of digoxin, a P-gp substrate. It is possible that the use of other P-gp substrates or higher doses of kava might still inhibit P-gp.
Ropinirole (Requip)
Taking kava with ropinirole might increase the risk for dopaminergic toxicity.
A case of visual hallucinations and paranoid delusions has been reported for a patient who used kava in combination with ropinirole. The adverse effects were attributed to kava-induced inhibition of CYP1A2, which may have reduced the metabolism of ropinirole, resulting in excessive dopaminergic stimulation.
Cytochrome P450 1A2 (Cyp1A2) Substrates
It is unclear if kava inhibits CYP1A2; research is conflicting.
Although in vitro research and a case report suggest that kava inhibits CYP1A2, more robust clinical evidence shows that kava has no effect on CYP1A2. In a clinical study in healthy volunteers, taking kava 1000 mg twice daily (containing a daily dose of 138 mg kavalactones) for 28 days had no effect on CYP1A2 activity.
Cytochrome P450 2D6 (Cyp2D6) Substrates
It is unclear if kava inhibits CYP1A2; research is conflicting.
In vitro research shows that kava extract significantly inhibits CYP2D6. However, clinical research shows that kava does not affect the metabolism of CYP2D6 substrates in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
It is unclear if kava inhibits CYP3AA; research is conflicting.
Although in vitro research suggests that kava inhibits CYP3A4, more robust clinical evidence shows that kava has no effect on CYP3A4. In a clinical study in healthy volunteers, taking kava 1000 mg twice daily (containing a daily dose of 138 mg kavalactones) for 28 days had no effect on CYP3A4 activity.
Bacopa Aerial Parts Extract
Anticholinergic Drugs
Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.
Cevimeline (Evoxac)
Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.
Cholinergic Drugs
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Thyroid Hormone
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.
Passionflower Aerial Parts Extract
Cns Depressants
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Research in animals and humans shows that passion flower has sedative effects which can be additive when used with sedative medications like lorazepam.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
In vitro research suggests that passion flower can induce CYP3A4 enzymes, albeit to a much lower degree than rifampin, a known CYP3A4 inducer.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, passion flower might reduce the bioavailability of OATP2B1 and OATP1A2 substrates.
In vitro research shows that the passion flower constituents apigenin and vitexin inhibit OATP2B1 and OATP1A2. This inhibition may be dose-dependent. One specific high-flavonoid passion flower extract (Valverde) seems to inhibit OATP2B1 and OATP1A2, while another extract with a lower flavonoid concentration (Arkocaps) shows less potent inhibition. OATPs are responsible for the uptake of drugs and other compounds into the body; however, the specific activities of OATP2B1 and OATP1A2 are not well characterized.
Lavender Flower Extract
Cns Depressants
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Laboratory research suggests that lavender has sedative effects. However, clinical studies in patients taking oral lavender oil (Silexan) 160 mg for 10 weeks or taking lavender flower powder 1 gram daily for 2 months have not reported side effects of drowsiness, sedation, or sleepiness. There is still some concern that higher doses or different preparations of lavender might have additive effects with CNS depressant medications.
Brand information
Manufacturer and brand details for Mind Soother Lavender, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Mind Soother Lavender by Herb Pharm: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mind Soother Lavender’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lavender
Interacts with 248 drugsLavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for a standardized oral lavender oil product for anxie...
Read the full Lavender monograph → Herb & supplement monographKava
Interacts with 1,166 drugsKava is a Pacific Island plant traditionally used to promote relaxation and ease anxiety, and some studies suggest it may help mild anxiety. However, kava has been linked to rare but serious...
Read the full Kava monograph → Herb & supplement monographBacopa
Interacts with 930 drugsBacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for several weeks, but the evidence is limite...
Read the full Bacopa monograph → Herb & supplement monographPassion Flower
Interacts with 836 drugsPassion flower is a traditional calming herb that many people use for anxiety and sleep. Early studies hint it may help with mild anxiety and restlessness, but the evidence is limited and mo...
Read the full Passion Flower monograph →Sources & How We Checked
Mind Soother Lavender's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 122 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lavender 20 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Akhondzadeh S, Kashani L, Fotouhi A, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 2003;27:123-7. PubMed
- Varma S, Blackford S, Statham BN, Blackwell A. Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. Contact Dermatitis 2000;42:309-10.
- Coulson IH and Khan AS. Facial 'pillow' dermatitis due to lavender oil allergy. Contact Dermatitis 1999;41(2):111. PubMed
- Woelk, H. and Schlafke, S. A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine. 2010;17(2):94-99. PubMed
- Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, plac
- Uehleke, B., Schaper, S., Dienel, A., Schlaefke, S., and Stange, R. Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder. Phytomedicine. 6-15-2012;19(8-9):665-671. PubMed
- Brandao FM. Occupational allergy to lavender oil. Contact Dermatitis 1986;15(4):249-250. PubMed
- Rademaker M. Allergic contact dermatitis from lavender fragrance in Difflam gel. Contact Dermatitis 1994;31(1):58-59. PubMed
- Kasper S, Gastpar M, Müller WE, et al. Lavender oil preparation Silexan is effective in generalized anxiety disorder--a randomized, double-blind comparison to placebo and paroxetine. Int J Neuropsychopharmacol. 2014 Jun;17(6):859-69. PubMed
- Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract 2018;31:132-8. PubMed
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