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Dietary supplement

Mucuna Extract Powder Ingredients & Drug Interactions

by Herbadiet

Mucuna Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mucuna Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Mucuna Extract Powder is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for parkinson's disease symptoms, male fertility and libido, mood and stress support.Based on those ingredients, 193 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Mucuna pruriens Seed Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Mucuna Extract Powder by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Mucuna Extract Powder by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Mucuna Extract Powder by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains one active ingredient: Mucuna pruriens seed extract standardized as a powder. Mucuna is a plant that naturally contains levodopa, a compound your body converts to dopamine—the same active ingredient used in Parkinson's disease medications.

The extract concentrates this compound, though the exact amount can vary between products and batches. There are no inactive ingredients listed for this formulation.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cowhage's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Natural aphrodisiac.
  • We looked for evidence on: Sexual desire, libido, erectile function, sexual performance.
  • The closest evidence on file: Cowhage is rated "Insufficient Reliable Evidence To Rate" for Sexual desire (Natural Medicines).

The evidence we have doesn't establish that this extract works for any of the conditions it's marketed for. The data shows insufficient reliable evidence to rate its use for anxiety, skin redness (erythema), high prolactin levels, muscle pain, Parkinson disease, or rheumatoid arthritis.

If you're thinking about trying it for one of these, talk it over with your doctor about what the science actually supports right now.

The evidence, ingredient by ingredient Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral adverse effects from Mucuna are generally rare, though a complete safety evaluation hasn't been done. The most commonly reported side effects are digestive—diarrhea, flatulence, and mucosal irritation—plus dry mouth and headaches.

In clinical studies using larger doses (22.5 to 67.5 grams daily in divided doses), a small number of participants experienced nausea, abdominal bloating, vomiting, and insomnia (about 3% in one trial). Because this product contains levodopa, an active drug-like compound, it should be used carefully and only under professional guidance.

During pregnancy, the safety data advises against use—there isn't enough data, and the dopamine effects raise concerns. While breastfeeding, avoid it as well: levodopa can lower prolactin levels and reduce milk supply.

Side effects, ingredient by ingredient Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cowhage.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you're on a monoamine oxidase inhibitor (MAOI), methyldopa, or any levodopa supplement—all carry major interaction risk. Also flag any blood pressure medications like guanethidine, antidiabetes drugs, antipsychotics, tricyclic antidepressants, or if you have surgery coming up (some anesthetics interact).

Because this product's levodopa content can vary, your exact dose matters for risk assessment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Herbadiet's Mucuna Extract Powder is a concentrated source of levodopa, and it carries significant interactions with common blood pressure, psychiatric, and diabetes medications—some of them serious. If you take any prescription drugs, especially for blood pressure, mood, diabetes, or Parkinson disease, or if you use an MAOI, check with your doctor or pharmacist before taking this.

The effectiveness for its marketed uses isn't established in the data we hold.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mucuna Extract Powder, straight from the product label.

Brand Herbadiet
Net contents 0 Not Present
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 293766
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mucuna Extract Powder by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
250 mg
Maximum serving Sizes:
500 mg
IngredientAmount% DV
Mucuna pruriens Seed Extract, Powder250 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Natural aprodisiac

Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast

V Vegan

Ethically sourced Scientifically tested Premium grade ingredients

Formula

Standardized extract powder Derived from mucuna pruriens seeds

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take up to 500 mg daily, or as directed by physician.

Precautions

Keep out of reach of children.

Pregnant or lactating women should consult your physician before use.

Storage

Store in a dry, cool & dark.

Best before 2 years from the date of mfg.

FDA Disclaimer Statement

Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Batch No. ARK-P20

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mucuna Extract Powder by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mucuna Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mucuna Extract Powder by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size250 mg Dosage formPowder Amounts shown are per serving.

Mucuna pruriens Seed Extract, Powder

Interacts with
193 drugs
250 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna pruriens Seed Extract, Powder monograph & interactions
Interaction report

Mucuna Extract Powder by Herbadiet Drug Interactions

Want to check YOUR meds against Mucuna Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
193Drugs
17 Major 176 Moderate

Ingredients driving the most interactions

Mucuna pruriens Seed Extract, Powder 193

Individual Drug Interactions

The ingredients in Mucuna Extract Powder interact with 193 drugs. Click any drug to see the details.

1 of the 1 ingredient in Mucuna Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Mucuna pruriens Seed Extract, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Mucuna Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mucuna pruriens Seed Extract, Powder8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna pruriens Seed Extract, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mucuna Extract Powder, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
Street Address
11, Sector - 14
City
Rohtak
State
Haryana
ZipCode
124001
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Mucuna Extract Powder by Herbadiet: Common Questions

Does Mucuna Extract Powder by Herbadiet interact with any medications?
Yes. Based on its ingredients, Mucuna Extract Powder has a known interaction with 193 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mucuna Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Mucuna pruriens, and why is it in this product?
Mucuna pruriens is a plant that contains levodopa, a compound your body converts to dopamine. Dopamine plays a role in mood, movement, and other functions. The extract concentrates this levodopa, which is why the product needs careful use and shouldn't be mixed with certain medications.
Can I take this while I'm pregnant or breastfeeding?
No—avoid it during pregnancy because safety data is insufficient and levodopa's dopamine effects raise concerns. If you're breastfeeding, skip it as well; levodopa can lower prolactin and reduce milk supply. Talk with your doctor or pharmacist if you're considering it during either time.
What are the most common side effects?
The most frequent are digestive: diarrhea, flatulence, stomach irritation, and dry mouth. Headaches have also been reported. In clinical studies using larger daily doses, a small number of people experienced nausea, bloating, vomiting, and insomnia.
Does this actually work for Parkinson disease, anxiety, or the other conditions it mentions?
The evidence we have is insufficient to establish effectiveness for any of those uses—Parkinson disease, anxiety, high prolactin, muscle pain, skin redness, or rheumatoid arthritis. If you're thinking about trying it for one of these conditions, ask your doctor what treatments have solid evidence.
Why do I need to check my medications so carefully with this product?
Because Mucuna contains levodopa, a potent compound that interacts with dozens of common drugs—blood pressure medications, antipsychotics, diabetes drugs, and MAOIs among them. Some interactions are major and can cause dangerous drops or spikes in blood pressure or reduce how your medications work. Your doctor or pharmacist needs to see your full medication list before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mucuna Extract Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mucuna Extract Powder label
Go deeper

The Full Monographs Behind Mucuna Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

Mucuna Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cowhage 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
  4. HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
  5. Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
  6. Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
  7. Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
  8. Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
  9. Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
  10. Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
  11. Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
  12. Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed

See these in context on the Cowhage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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