Pre-Menopause By Estroven Overview & Drug Interactions

Black cohosh (Actaea racemosa) is a perennial plant native to North America and is sometimes referred to as "black snakeroot" or "bugbane". Black cohosh is often taken as a supplement to help with menopause symptoms, such as hot flashes, night sweats, and mood changes. It is also sometimes used to help with premenstrual syndrome (PMS) and other menstrual issues. Black cohosh supplements are typically standardized for their triterpene glycoside content.

Cissus quadrangularis is a vine plant from the grape family, traditionally used for promoting bone fracture healing and treating digestive disorders. It contains various beneficial compounds like flavonoids, steroids, and antioxidants. Studies in animals have shown that Cissus quadrangularis may stimulate new bone growth, promote the activity of bone-building cells called osteoblasts, increase bone thickness, and reduce the activity of bone-degrading cells called osteoclasts. Research suggests these bone-promoting effects are mediated by specific molecular pathways and increasing the expression of key bone development genes in osteoblasts. Other uses of Cissus quadrangularis include supporting weight loss, blood sugar control and improving joint pain.