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Dietary supplement

Pro Recover Tribulus 4500 Ingredients & Drug Interactions

by Ten Performance

Pro Recover Tribulus 4500 label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pro Recover Tribulus 4500 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pro Recover Tribulus 4500 is a dietary supplement by Ten Performance with 2 active ingredients. Its ingredients are commonly taken for athletic performance and strength, energy and fatigue, joint health and arthritis.Based on those ingredients, 311 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tribulus terrestris aerial parts extract, Velvet Antler extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pro Recover Tribulus 4500 by Ten Performance

Ask about any prescription or over-the-counter medication and we check it for interactions with Pro Recover Tribulus 4500 by Ten Performance — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pro Recover Tribulus 4500 by Ten Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (175 mg) without saying how much of each component you get.

Pro Recover Tribulus 4500 contains 2 active ingredients. The main one is tribulus terrestris aerial parts extract, a plant used traditionally for sexual function and athletic performance.

The other is velvet antler extract, made from deer antler, which some use for wound healing and joint support. The product is a liquid and also contains water and grape alcohol as inactive ingredients.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: athletic performance and muscle recovery support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Strength, Endurance.
  • The closest evidence on file: Tribulus is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.
  • Also on file: Deer Velvet is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.

For tribulus, the evidence suggests it may be effective for sexual dysfunction — that's the one area where clinical data leans supportive. For athletic performance, the evidence actually suggests it's likely ineffective, so don't expect a boost there.

For benign prostatic hyperplasia (an enlarged prostate), the evidence isn't established in the data we hold. Deer velvet shows insufficient evidence for wound healing, heart disease, high blood pressure, bone density, sexual desire, and aging — meaning research hasn't yet shown it works reliably for these uses.

If you're considering this product for one of those purposes, the science doesn't back it up yet.

The evidence, ingredient by ingredient Deer Velvet Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus is generally well tolerated short-term in healthy adults, though long-term safety data are limited. Gastrointestinal side effects like stomach pain, nausea, cramping, diarrhea, and constipation can happen, though in one study they occurred at similar rates in people taking tribulus and those taking placebo.

Rare serious side effects including liver and kidney injury and seizures have been reported. Deer velvet appears generally well tolerated in short-term use, but long-term safety isn't well studied.

Avoid both ingredients during pregnancy — there isn't enough safety data. Avoid tribulus while breastfeeding; safety information on deer velvet during breastfeeding is also insufficient, so it's best avoided then too.

Side effects, ingredient by ingredient Deer Velvet Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Tribulus, Deer Velvet.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 311 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Pro Recover Tribulus 4500, double-check it with your pharmacist if you're on blood pressure medications or diabetes medications — tribulus may intensify their effects. If you take lithium, let your pharmacist know before starting.

Also flag it if you use hormonal birth control or estrogen therapy, even though those interactions are minor.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is built around tribulus for sexual function, where the evidence is moderately supportive. If you take blood pressure or diabetes medications, or if you take lithium, check with your pharmacist before starting — tribulus can affect how these drugs work.

Pregnant or nursing? Skip it.

For anyone else without those medications, discuss it with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pro Recover Tribulus 4500, straight from the product label.

Brand Ten Performance
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 287124
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pro Recover Tribulus 4500 by Ten Performance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
30 Drop(s)
Servings per container
30
IngredientAmount% DV
Proprietary Blend175 mg--
Velvet Antler extract0 NP--
Tribulus terrestris aerial parts extract0 NP--

Other ingredients: Water, Purified, Grape Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Shake well before each use. Take 30 drops (2/3 of a dropper) and hold in mouth under tongue for 90 seconds. Swallow afterwards. Use in the morning on an empty stomach.

General Statements

Elite

FDA Statement of Identity

Dietary Supplement

Precautions

Warnings: If you are pregnant or breastfeeding, consult a health care practitioner before using.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pro Recover Tribulus 4500 by Ten Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pro Recover Tribulus 4500 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pro Recover Tribulus 4500 by Ten Performance

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

175 mg per serving

Other (inactive) ingredients: Water, Purified, Grape Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pro Recover Tribulus 4500 by Ten Performance Drug Interactions

Want to check YOUR meds against Pro Recover Tribulus 4500?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
311Drugs
259 Moderate 52 Minor

Ingredients driving the most interactions

Tribulus terrestris aerial parts extract 259
Velvet Antler extract 52

Individual Drug Interactions

The ingredients in Pro Recover Tribulus 4500 interact with 311 drugs. Click any drug to see the details.

2 of the 2 ingredients in Pro Recover Tribulus 4500 interact with drugs. Each result below shows which ingredient is responsible. Tribulus terrestris aerial parts extract Velvet Antler extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Pro Recover Tribulus 4500 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Tribulus terrestris aerial parts extract3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus terrestris aerial parts extract full monograph & interactions

Velvet Antler extract2 drug types · 52 drugs

Contraceptive Drugs

Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Laboratory research shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.

Likelihood Unlikely Evidence D
Estrogens

Theoretically, deer velvet might increase the effects and side effects of estrogens.
Laboratory evidence shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.

Likelihood Unlikely Evidence D
Velvet Antler extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pro Recover Tribulus 4500, from the product label.

Ten Performance

See all Ten Performance products
Name
TEN Performance
City
Tampa
State
FL
ZipCode
33626
Phone Number
800-640-4045
Web Address
TENperformance.com
Pharmacist Counseling Corner

Pro Recover Tribulus 4500 by Ten Performance: Common Questions

Does Pro Recover Tribulus 4500 by Ten Performance interact with any medications?
Yes. Based on its ingredients, Pro Recover Tribulus 4500 has a known interaction with 311 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pro Recover Tribulus 4500 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for erectile dysfunction?
Tribulus, the main ingredient, has possibly effective evidence for sexual dysfunction — meaning clinical research suggests it may help, though the evidence isn't airtight. Results vary person to person, so talk with your pharmacist about whether it's worth trying for you.
What's velvet antler and why is it in here?
Velvet antler is an extract made from deer antler. It's included in formulas targeting sexual function and overall recovery, though the evidence that it actually works for those purposes isn't well established yet.
Can I take this if I'm trying to get pregnant?
No — avoid tribulus and deer velvet during pregnancy. The safety data aren't there, and tribulus may affect hormones. Talk with your doctor about what's safe for you.
What side effects should I watch for?
Most people taking tribulus don't have issues, but stomach upset (pain, nausea, cramping, diarrhea, constipation) can happen. Rarely, serious problems like liver or kidney injury and seizures have been reported. If anything feels off, stop and call your pharmacist.
Is this safe long-term?
The research doesn't cover long-term use well, and product quality varies. Short-term use in healthy adults looks okay, but we don't have solid data on what happens if you take it for months or years.
Does this boost athletic performance?
No — the evidence actually suggests tribulus is likely ineffective for athletic performance, so don't expect a workout edge from this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pro Recover Tribulus 4500 is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pro Recover Tribulus 4500 label
Go deeper

The Full Monographs Behind Pro Recover Tribulus 4500’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Deer Velvet

Interacts with 52 drugs

Deer velvet is a traditional remedy made from the soft, growing antlers of deer or elk, and it is most often promoted for energy, athletic performance, and joint health. Good-quality human e...

Read the full Deer Velvet monograph → Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph →
Sources

Sources & How We Checked

Pro Recover Tribulus 4500's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deer Velvet 2 references
  1. Sleivert, G., Burke, V., Palmer, C., Walmsley, A., Gerrard, D., Haines, S., and Littlejohn, R. The effects of deer antler velvet extract or powder supplementation on aerobic power, erythropoiesis, and muscular strength and endurance characteristics. Int PubMed
  2. Bubenik, G. A., Miller, K. V., Lister, A. L., Osborn, D. A., Bartos, L., and van der Kraak, G. J. Testosterone and estradiol concentrations in serum, velvet skin, and growing antler bone of male white-tailed deer. J Exp Zoolog.A Comp Exp Biol 3-1-2005;30 PubMed

See these in context on the Deer Velvet monograph →

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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