Probiotic 40 Billion Ingredients & Drug Interactions
by dr.bo
What is this page for?
First and foremost: checking Probiotic 40 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic 40 Billion is a dietary supplement by dr.bo with 6 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus LA-14, Lactiplantibacillus plantarum Lp-115. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Probiotic 40 Billion by dr.bo
Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic 40 Billion by dr.bo — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Probiotic 40 Billion by dr.bo
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has 6 active ingredients: four probiotic bacterial strains (Bifidobacterium animalis lactis, Lactobacillus acidophilus, Lactobacillus paracasei, and Lactiplantibacillus plantarum), plus fructooligosaccharides (a plant fiber that feeds beneficial bacteria) and marine polysaccharides. The inactive ingredients are cellulose, rice maltodextrin, and L-leucine — standard capsule fillers and binders.
Does it work?
Moderate evidence
The evidence for probiotics in this product is mixed. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis.
Lactiplantibacillus plantarum is possibly effective for eczema, high cholesterol, ulcerative colitis, and common cold prevention. Fructooligosaccharides, however, has insufficient evidence to rate it — we don't have strong data showing it works for constipation, diabetes, bone health, or cholesterol.
For the other probiotic strains in this product, effectiveness data isn't established in what we hold.
How safe is it?
Well-documented data
Lactobacillus acidophilus and Lactiplantibacillus plantarum are generally well tolerated in healthy people. The main caution: because these are live organisms, they theoretically could cause serious infection in patients with severely weakened immune systems or certain serious illnesses — check with your doctor first if that's you.
Fructooligosaccharides commonly causes gas, bloating, and abdominal pain, especially at higher doses, though a review of clinical studies suggests doses under 10 grams daily tend to be mild. Both probiotic strains can occasionally cause mild digestive side effects like abdominal pain, bloating, flatulence, and diarrhea, but these are uncommon.
We have no pregnancy or lactation safety data on file for the probiotic bacteria in this product.
Meds to double-check
Moderate interaction found
Antibiotic drugs are the main medication type to double-check — taking them at the same time as this product (Moderate severity) may reduce how well the probiotics survive. Separate your antibiotic and probiotic doses by a few hours.
Use the search tool below to check your exact medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This probiotic is worth considering if you have irritable bowel syndrome, antibiotic-related diarrhea, or eczema — the evidence for those is solid. If you're on antibiotics, time your doses several hours apart from this product so the antibiotics don't kill the live cultures.
Talk to your pharmacist before starting if you have a weakened immune system or serious illness.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic 40 Billion, straight from the product label.
| Brand | dr.bo |
|---|---|
| Barcode (UPC) | X003A75QXR |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 328694 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic 40 Billion by dr.bo, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium animalis lactis BL-04 | 0 NP | -- |
| Fructooligosaccharides | 0 NP | -- |
| Lactobacillus acidophilus LA-14 | 0 NP | -- |
| Lactobacillus paracasei LPC-37 | 0 NP | -- |
| Marine Polysaccharides | 0 NP | -- |
| Lactiplantibacillus plantarum Lp-115 | 0 NP | -- |
| Proprietary Blend of Probiotic Bacteria | 0 NP | -- |
Other ingredients: Cellulose, Rice Maltodextrin, L-Leucine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
dr.bo Probitic 40 billion contains a specialized blend of live organisms to support digestive health and promote healthy flora balance.
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Suggested/Recommended/Usage/Directions
Suggested use: Take 2 capsules once daily or as directed by your healthcare professional. For best results, take 1 capsule in the morning and 1 capsule in the evening.
Formulation
Zero added artificial colors, flavors, chemicals or preservatives.
Gluten free Dairy Free Soy free GMO Free
Patented Maktrek Bi-Pass Technology Promotes healthy flora balance Supports gut & digestive health
Formula
This product is formulated with 40 billion CFU per 2 caps.
Probiotic 40 Billion with Acidophilus (LA-14)
With Prebiotic Fructooligosaccharide
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Facebook Instagram Follow us: @DRBO Nutrition
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Made in USA Lab Tested Made in FDA Registered Facility GMP Sourced from a GMP Certified Facility
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic 40 Billion by dr.bo label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic 40 Billion by dr.bo
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend of Probiotic Bacteria
- › Bifidobacterium animalis lactis BL-04
- › Fructooligosaccharides
- › Lactobacillus acidophilus LA-14
- › Lactobacillus paracasei LPC-37
- › Marine Polysaccharides
- › Lactiplantibacillus plantarum Lp-115
Other (inactive) ingredients: Cellulose, Rice Maltodextrin, L-Leucine. These complete the product’s ingredient list but are not active constituents.
Probiotic 40 Billion by dr.bo Drug Interactions
HelloPharmacist Interaction Report
Probiotic 40 Billion by dr.bo contains several probiotic strains, and we've found documented interactions with one drug type.
The most serious concern is with antibiotic drugs — both Lactobacillus acidophilus and Lactiplantibacillus plantarum may be killed by antibiotics taken at the same time, which could reduce how well the probiotics work. The effect is rated Moderate for both.
Read the full breakdown — every affected drug type, severity by severity
Fructooligosaccharides (the prebiotic in this product, which feeds the probiotics) has no documented interactions with medications. However, we could not check three ingredients — Bifidobacterium animalis lactis BL-04, Lactobacillus paracasei LPC-37, and Marine Polysaccharides — because we hold no data on them yet.
Altogether, these interactions span 182 individual medications. If you take antibiotics, talk to your pharmacist about spacing them apart from this product — usually a few hours between doses helps.
Use the medication checker on this page to see if any of your prescriptions are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Probiotic 40 Billion?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Probiotic 40 Billion interact with 182 drugs. Click any drug to see the details.
2 of the 6 ingredients in Probiotic 40 Billion interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus LA-14 Lactiplantibacillus plantarum Lp-115
AmikacinAmikin, Arikayce
How Amikacin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Amikacin interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin Veterinary interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin, Clavulanate Potassium interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Amphotericin, Tetracycline interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Ampicillin interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Ampicillin, Sulbactam interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Avibactam Sodium, Ceftazidime interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Azithromycin interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Aztreonam interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Bacampicillin interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Bacitracin interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Benznidazole interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Capreomycin interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Carbenicillin Indanyl Sodium interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefaclor interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefadroxil interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefamandole interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefazolin interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefdinir interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefditoren Pivoxil interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefepime interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefiderocol Sulfate Tosylate interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefixime interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefmetazole interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefonicid interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefoperazone interactionLactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Probiotic 40 Billion — through 2 ingredients. Tap an ingredient for the detail:
Lactiplantibacillus Plantarum Lp-115Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactiplantibacillus Plantarum Lp-115 + Cefotaxime interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Probiotic 40 Billion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus acidophilus LA-14
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Lactiplantibacillus plantarum Lp-115
Antibiotic Drugs
Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L. plantarum.
L. plantarum preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. plantarum preparations by at least two hours.
Brand information
Manufacturer and brand details for Probiotic 40 Billion, from the product label.
dr.bo
See all dr.bo products- Name
- DR.BO
- Street Address
- 4335 Van Nuys Blvd #160
- City
- Sherman Oaks
- State
- Ca
- ZipCode
- 91403
- Phone Number
- 1-844-910-3726
- Web Address
- drbo.com
Probiotic 40 Billion by dr.bo: Common Questions
Does Probiotic 40 Billion by dr.bo interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this probiotic help with IBS or diarrhea?
What if I'm taking antibiotics right now?
Will this give me gas and bloating?
Is this safe if I have a weak immune system?
Can I take this while pregnant or breastfeeding?
Does the fructooligosaccharides actually do anything?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Probiotic 40 Billion’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Fructo-oligosaccharides (fos)
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...
Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographLactiplantibacillus Plantarum
Interacts with 182 drugsLactiplantibacillus plantarum is a 'friendly' bacterium (probiotic) found in fermented foods and many supplements, studied mainly for digestive health. It is generally well tolerated in heal...
Read the full Lactiplantibacillus Plantarum monograph →Sources & How We Checked
Probiotic 40 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 33 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fructo-oligosaccharides (fos) 6 references
- Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
- Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
- Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
- Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed
See these in context on the Fructo-oligosaccharides (fos) monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Lactiplantibacillus Plantarum 12 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Ducrotté P, Sawant P, Jayanthi V. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World J Gastroenterol 2012;18(30):4012-8.
- Krag A, Munkholm P, Israelsen H, von Ryberg B, Andersen KK, Bendtsen F. Profermin is efficacious in patients with active ulcerative colitis--a randomized controlled trial. Inflamm Bowel Dis. 2013;19(12):2584-92. PubMed
- Topcuoglu S, Gursoy T, Ovali F, Serce O, Karatekin G. A new risk factor for neonatal vancomycin-resistant Enterococcus colonisation: bacterial probiotics. J Matern Fetal Neonatal Med. 2015;28(12):1491-4. PubMed
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Axling U, Önning G, Martinsson Niskanen T, Larsson N, Hansson SR, Hulthén L. The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women: A randomized clinical trial. Acta Obstet Gynecol Scand
- Matsuura H, Kiura Y, Ito T, et al. Lactobacillus bacteremia: a diagnostic clue of rectal cancer. QJM. 2021;114(2):122-123. PubMed
- Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N. Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, doub
- Busch R, Gruenwald J, Dudek S. Randomized, double blind and placebo controlled study using a combination of two probiotic lactobacilli to alleviate symptoms and frequency of common cold. Food Nutr Sci 2013;4(11A):13-2. DOI
- Bengtsson J, Adlerberth I, Östblom A, Saksena P, Öresland T, Börjesson L. Effect of probiotics (Lactobacillus plantarum 299 plus Bifidobacterium Cure21) in patients with poor ileal pouch function: a randomised controlled trial. Scand J Gastroenterol 2016;
- Canaviri-Paz P, Oscarsson E, Kjellström A, Olsson H, Jois C, Håkansson Å. Effects on Microbiota Composition after Consumption of Quinoa Beverage Fermented by a Novel Xylose-Metabolizing L. plantarum Strain. Nutrients 2021;13(10):3318. PubMed
See these in context on the Lactiplantibacillus Plantarum monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC