Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Respira Hemp Oil Natural Ingredients & Drug Interactions

by Elixinol

Respira Hemp Oil Natural label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Respira Hemp Oil Natural against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Respira Hemp Oil Natural is a dietary supplement by Elixinol with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Respira Hemp Oil Natural by Elixinol

Ask about any prescription or over-the-counter medication and we check it for interactions with Respira Hemp Oil Natural by Elixinol — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Respira Hemp Oil Natural by Elixinol

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Respira Hemp Oil Natural contains 2 active ingredients: cannabidiol and hemp oil. These are delivered in a liquid form with vegetable glycerin as an inactive ingredient (excipient).

Hemp oil is derived from hemp seeds and contains compounds that research has studied for various health purposes. Cannabidiol, often called CBD, is another compound found in hemp.

Together, they make up the active content of this supplement.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for hemp oil's effectiveness is insufficient to rate it for constipation, eczema (atopic dermatitis), or familial hypercholesterolemia — these are the conditions studied, but the data doesn't support a clear conclusion either way. For cannabidiol, we have no effectiveness ratings on file.

If you're considering this product for a specific health reason, talk with your pharmacist or doctor about what the current evidence actually shows.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods in normal amounts are generally well tolerated. However, concentrated extracts and supplements like this one are less well studied, so caution is advised.

In larger amounts, hemp seed oil still appears well tolerated overall. Rare serious side effects have been reported: anaphylaxis (severe allergic reaction), long QT syndrome and related heart rhythm problems, and syncope (fainting).

Allergic reactions to hemp seed — including hives, facial swelling, shortness of breath, and worsening asthma — are uncommon but documented. There is one case report of elevated liver enzymes and hepatitis in a young child given very high doses of hemp extract.

Pregnancy and lactation safety data are not on file for this product; talk with your doctor or pharmacist before use if you're pregnant or nursing.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check this product against estrogen therapies (hormone medications) before starting — that's your highest-severity interaction. Also double-check it with blood thinners like warfarin, blood pressure medications, and any drugs your liver breaks down via CYP1A2 or CYP3A4 enzymes — these are all Minor interactions, but they matter.

Your pharmacist can help identify which of your medications fall into these categories.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take estrogen therapy or blood thinners, or if you take blood pressure medications, this product warrants a medication check first — ask your pharmacist to run it through the interaction checker. This supplement is generally well tolerated in typical use, but concentrated hemp extracts are less studied than whole hemp foods, and rare serious reactions have been reported.

Your pharmacist can help you weigh the risks and benefits for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Respira Hemp Oil Natural, straight from the product label.

Brand Elixinol
Net contents 0.5 oz; 15 mL
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 239639
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Respira Hemp Oil Natural by Elixinol, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.5 mL
Maximum serving Sizes:
1.5 mL
Servings per container
30
IngredientAmount% DV
Cannabidiol10 mg--
Hemp Oil33.3 mg--

Other ingredients: Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Use: Twice daily, or as needed.

Storage

Storage: In order to preserve freshness store away from excessive heat, light, and humidity.

Precautions

Tamper resistant: Use only if the safety seal is intact.

Warning: If pregnant, or nursing, consult your physician before taking this or any other supplement.

Keep out of reach of children.

Formula

Elixinol Hemp Oil is made from organically grown industrial hemp plants.

Hemp Oil with naturally occurring CBD

Cannabidiol is a natural constituent of Hemp oil.

Formulation

Elixinol Hemp Oil is made from organically grown industrial hemp plants.

Our oil is cold-processed using CO2 super-critical fluid extraction.

Respira is a solvent free, PG & PEG free, and THC free whole plant product.

Natural

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the Food & Drug Administration.

FDA Statement of Identity

Dietary Supplement

General Statements

300

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Respira Hemp Oil Natural by Elixinol label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Respira Hemp Oil Natural label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Respira Hemp Oil Natural by Elixinol

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.5 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cannabidiol

10 mg per serving

Hemp Oil

Interacts with
938 drugs
33.3 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Hemp Oil monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Respira Hemp Oil Natural by Elixinol Drug Interactions

Want to check YOUR meds against Respira Hemp Oil Natural?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Hemp Oil 938

Individual Drug Interactions

The ingredients in Respira Hemp Oil Natural interact with 938 drugs. Click any drug to see the details.

1 of the 2 ingredients in Respira Hemp Oil Natural interact with drugs. Each result below shows which ingredient is responsible. Hemp Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Respira Hemp Oil Natural with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hemp Oil6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Hemp Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Respira Hemp Oil Natural, from the product label.

Elixinol

See all Elixinol products
Name
Elixinol LLC
City
Boulder
State
CO
ZipCode
80301
Web Address
www.elixinol.com
Pharmacist Counseling Corner

Respira Hemp Oil Natural by Elixinol: Common Questions

Does Respira Hemp Oil Natural by Elixinol interact with any medications?
Yes. Based on its ingredients, Respira Hemp Oil Natural has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Respira Hemp Oil Natural contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any serious side effects?
Serious side effects are rare, but they have been reported: anaphylaxis (severe allergic reaction), heart rhythm problems, and fainting. Allergic reactions to hemp seed — including facial swelling and difficulty breathing — are uncommon but real. One case report described liver problems in a child given very high doses. At typical doses, hemp seed oil appears well tolerated, but concentrated extracts are less studied than whole hemp foods.
Is it safe to take while pregnant or nursing?
We don't have safety data on file for this product in pregnancy or lactation. That means we can't tell you it's safe or unsafe — there simply isn't enough information. Talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.
Can I take this if I'm allergic to hemp seed?
No. If you've had any allergic reaction to hemp seed — even a mild one like hives — avoid this product. Allergic reactions to hemp can be serious and may worsen with repeat exposure.
Does the effectiveness evidence show this actually works?
The evidence we hold rates it as insufficient for the conditions studied: constipation, eczema, and high cholesterol. That means the research doesn't support a clear conclusion either way. If you're thinking about using it for one of these, talk with your pharmacist about what the science actually shows.
What's the difference between this and regular hemp seed oil?
This is a concentrated supplement extract, not the whole food. The safety notes in our data flag concentrated hemp extracts as less well studied than regular hemp seed foods. That's why caution is advised — we simply know less about concentrated forms than we do about hemp seeds you'd eat.
Why can't you check cannabidiol for interactions?
We hold no data on cannabidiol interactions — it wasn't in our monograph at the time we reviewed this product. That doesn't mean it has no interactions; it just means we couldn't check it. Ask your pharmacist if they have more recent data on CBD interactions with your medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Respira Hemp Oil Natural is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Respira Hemp Oil Natural label
Go deeper

The Full Monographs Behind Respira Hemp Oil Natural’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Respira Hemp Oil Natural's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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