Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

S. Boulardii SAP Ingredients & Drug Interactions

by NFH

S. Boulardii SAP label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking S. Boulardii SAP against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

S. Boulardii SAP is a dietary supplement by NFH with 1 active ingredient. Its ingredients are commonly taken for source of b vitamins, diarrhea (certain types), cold and flu support.Based on those ingredients, 136 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Saccharomyces cerevisiae var. boulardii CNCM I-1079. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against S. Boulardii SAP by NFH

Ask about any prescription or over-the-counter medication and we check it for interactions with S. Boulardii SAP by NFH — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.
Computed from our clinical databases

HelloPharmacist Scorecard of S. Boulardii SAP by NFH

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
Known Interaction Concern
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Brewer's Yeast.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 136 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about S. Boulardii SAP, straight from the product label.

Brand NFH
Barcode (UPC) 856711001726
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 273218
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for S. Boulardii SAP by NFH, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
856711001726
IngredientAmount% DV
Saccharomyces cerevisiae var. boulardii CNCM I-10790 NP--

Other ingredients: Vegetable Hypromellose, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

S. Boulardii SAP is a single-strain probiotic to support the immune system and promote gastrointestinal health, particularly following antibiotic use.

All ingredients listed for this product lot number have been tested by a third-party laboratory for identity, potency, heavy metals, CFUs, and purity.

Contains no: Gluten, soy, wheat, corn, eggs, dairy, citrus, preservatives, artificial flavor or color, starch, or sugar.

This product is non-GMO and vegan friendly.

This product is non-GMO and vegan friendly.

Color, size and smell may vary from one lot to another.

Made in Canada

Suggested/Recommended/Usage/Directions

Directions for use: Children 6-12 years old, adolescents 13-17 years old, and adults: Take 1 capsule one to three times daily or as directed by your healthcare practitioner.

Precautions

Cautions and warnings: Discontinue use and consult a healthcare practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond 3 days.

Contraindications: Do not use if you have nausea, fever, vomiting, bloody diarrhea, severe abdominal pain, or an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment).

Do not use if seal is broken.

Keep out of reach of children.

Storage

Keep refrigerated.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Probiotic

FDA Statement of Identity

Dietary Supplement

General Statements

NPN 80024409

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

S. Boulardii SAP by NFH label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

S. Boulardii SAP label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in S. Boulardii SAP by NFH

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Saccharomyces cerevisiae var. boulardii CNCM I-1079

Interacts with
136 drugs
0 NP per serving

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some...

Saccharomyces cerevisiae var. boulardii CNCM I-1079 monograph & interactions

Other (inactive) ingredients: Vegetable Hypromellose, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

S. Boulardii SAP by NFH Drug Interactions

S. Boulardii SAP contains a single active ingredient, and it has known interactions with 136 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against S. Boulardii SAP?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
136Drugs
9 Major 87 Moderate 40 Minor

Ingredients driving the most interactions

Saccharomyces cerevisiae var. boulardii CNCM I-1079 136

Individual Drug Interactions

The ingredients in S. Boulardii SAP interact with 136 drugs. Click any drug to see the details.

1 of the 1 ingredient in S. Boulardii SAP interact with drugs. Each result below shows which ingredient is responsible. Saccharomyces cerevisiae var. boulardii CNCM I-1079

Each ingredient & the kinds of drugs it affects

For each ingredient in S. Boulardii SAP with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Saccharomyces cerevisiae var. boulardii CNCM I-10794 drug types · 136 drugs

Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking brewer's yeast with MAOIs might increase the risk of hypertension.
Brewer's yeast contains tyramine. Taking brewer's yeast with MAOIs might increase the risk for hypertensive crisis.

Likelihood Likely Evidence D
Antidiabetes Drugs

Taking brewer's yeast with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking chromium-containing brewer's yeast can decrease levels of blood glucose in diabetic patients being treated with antidiabetes drugs.

Likelihood Possible Evidence B
Lithium

Theoretically, taking brewer's yeast with lithium might cause additive effects and side effects.
Some brewer's yeast products contains lithium.

Likelihood Possible Evidence D
Antifungals

Theoretically, taking antifungals with some brewer's yeast products might decrease the effectiveness of brewer's yeast.
Some brewer's yeast products contain live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces cerevisiae var. boulardii CNCM I-1079 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for S. Boulardii SAP, from the product label.

NFH

See all NFH products
Name
NFH - Nutritional Fundamentals for Health, Inc.
Street Address
351 Rue Joseph-Carrier
City
Vaudreuil
State
QC
ZipCode
J7V 5V5
Phone Number
1 866 510-3123
Web Address
nfh.ca
Pharmacist Counseling Corner

S. Boulardii SAP by NFH: Common Questions

Does S. Boulardii SAP by NFH interact with any medications?
Yes. Based on its ingredients, S. Boulardii SAP has a known interaction with 136 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
S. Boulardii SAP contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if S. Boulardii SAP is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

S. Boulardii SAP label
Go deeper

The Full Monographs Behind S. Boulardii SAP’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Brewer's Yeast

Interacts with 136 drugs

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some types of diarrhea. Most other health cla...

Read the full Brewer's Yeast monograph →
Sources

Sources & How We Checked

S. Boulardii SAP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Brewer's Yeast 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  3. Bahijiri, S. M., Mira, S. A., Mufti, A. M., and Ajabnoor, M. A. The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes. Saudi.Med.J. 2000;21(9):831-837. DOI
  4. Schrauzer, G. N. and de, Vroey E. Effects of nutritional lithium supplementation on mood. A placebo-controlled study with former drug users. Biol.Trace Elem.Res. 1994;40(1):89-101. PubMed
  5. Gayathri R, Aruna T, Malar S, Shilpa B, Dhanasekar KR. Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome. Int J Colorectal Dis. 2020;35(1):139-145. PubMed
  6. Mourey F, Decherf A, Jeanne JF, et al. Saccharomyces cerevisiae I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol 2022;28(22):2509-2522.

See these in context on the Brewer's Yeast monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team