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Dietary supplement

Sheep Sorrel Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sheep Sorrel is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, digestive upset, fever.Based on those ingredients, 169 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Sheep Sorrel (Rumex acetosella) dried herb liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sheep Sorrel by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic Sheep Sorrel (Rumex acetosella) in dried herb liquid extract form. Sorrel is a leafy plant traditionally used for respiratory and other purposes, though current evidence for those uses is limited.

The only other ingredient is the menstruum — the liquid base used to extract and preserve the herb.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sorrel product and its label doesn't state a use — see Sorrel's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for Sheep Sorrel isn't established in our data. We hold insufficient reliable evidence to rate it for bronchitis, breast cancer, or rhinosinusitis — the conditions it's most commonly associated with.

That doesn't mean it doesn't work; it means the research either isn't there yet or hasn't reached a clear conclusion. If you're considering it for a specific health concern, talk with your pharmacist or doctor about what the current science actually supports.

The evidence, ingredient by ingredient Sorrel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sheep Sorrel is generally well tolerated in food amounts, but there's a real caveat: it's high in oxalates, minerals that can cause kidney problems in large or concentrated doses. Cases of kidney damage from sorrel consumption have been reported, including one child who developed kidney inflammation after eating wild sorrel.

If you have kidney disease or a history of kidney stones, this product isn't for you. Some people may have allergic reactions — sorrel pollen can trigger allergic rhinitis or asthma in sensitive individuals, and up to 19% of people allergic to weed pollen may react to sorrel too.

When sorrel is combined with other herbs, nausea and an unpleasant aftertaste have been reported. Safety data for medicinal use while breastfeeding is limited, so talk with your doctor or pharmacist before using it if you're nursing.

Side effects, ingredient by ingredient Sorrel

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sorrel.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 169 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Sheep Sorrel, check if you're on any blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel) — sorrel may increase bleeding risk. Also confirm any medications that rely on intestinal absorption with OATP transporters, including the antihistamine fexofenadine (Allegra).

The medication checker on this page can help identify these.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-herb extract with several documented drug interactions, especially with blood thinners and allergy medications. The oxalate content makes it risky if you have kidney concerns.

Check your exact medications with the tool on this page before you start, and talk with your pharmacist — especially if you take a blood thinner or fexofenadine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sheep Sorrel, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 0606595845561
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235294
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sheep Sorrel by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
0606595845561
IngredientAmount% DV
certified organic Sheep Sorrel (Rumex acetosella) dried herb liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: USA.

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Rumex acetosella

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

See for yourself

Sheep Sorrel by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sheep Sorrel by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

970 mg per serving

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for an...

Certified organic Sheep Sorrel (Rumex acetosella) dried herb liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sheep Sorrel by Herbal Terra Drug Interactions

Want to check YOUR meds against Sheep Sorrel?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
169Drugs
169 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Sheep Sorrel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Sheep Sorrel (Rumex acetosella) dried herb liquid extract3 drug types · 169 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Sheep Sorrel, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Sheep Sorrel by Herbal Terra: Common Questions

Does Sheep Sorrel by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Sheep Sorrel has a known interaction with 169 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sheep Sorrel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Sheep Sorrel safe if I have kidney problems?
No. Sorrel is high in oxalates, compounds that can damage your kidneys in concentrated amounts. Cases of kidney inflammation have been reported from sorrel use. If you have kidney disease or a history of kidney stones, avoid this product and talk with your doctor first.
Can I take this while breastfeeding?
There isn't enough safety data to say either way. Medicinal or concentrated amounts of sorrel haven't been proven safe during breastfeeding. Talk with your doctor or pharmacist for personalized advice before taking it.
Does Sheep Sorrel actually work for bronchitis or other conditions?
We don't have reliable evidence yet. The research for bronchitis, breast cancer, and rhinosinusitis is insufficient to rate it. That means either studies haven't been done or results haven't been conclusive. Ask your pharmacist what the current science shows for your specific reason for using it.
What side effects should I watch for?
Kidney problems are the most serious risk, especially with repeated use. Allergic reactions — including asthma or allergic rhinitis — can happen if you're sensitive to weed pollen. Nausea and an unpleasant aftertaste have been reported when sorrel is mixed with other herbs. Stop and call your doctor if you notice unusual urination, swelling, or trouble breathing.
Will this interfere with my allergy medications?
Yes, potentially. Sorrel may reduce how well fexofenadine (Allegra) is absorbed, making it less effective. It can also interfere with other medications that rely on intestinal transporters to work. Use the medication checker on this page to be sure about your specific drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sheep Sorrel label
Sources

Sources & How We Checked

Sheep Sorrel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sorrel 8 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
  5. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
  6. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
  7. Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
  8. Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed

See these in context on the Sorrel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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