Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Super Mandro Ingredients & Drug Interactions

by Hard Rock Supplements

Super Mandro label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Super Mandro against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Super Mandro is a dietary supplement by Hard Rock Supplements with 1 active ingredient. Its ingredients are commonly taken for muscle building, increasing strength, athletic performance.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 3-beta-hydroxy-5-alpha-androst-1-en-17-one. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Super Mandro by Hard Rock Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Super Mandro by Hard Rock Supplements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.
Computed from our clinical databases

HelloPharmacist Scorecard of Super Mandro by Hard Rock Supplements

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 1-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Mandro, straight from the product label.

Brand Hard Rock Supplements
Net contents 90 Capsule(s)
Market status Off market
Date entered into DSLD Dec 22, 2019
DSLD ID 209941
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Mandro by Hard Rock Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
IngredientAmount% DV
3-beta-hydroxy-5-alpha-androst-1-en-17-one110 mg--

Other ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bulking series Gains of steel

Formulation

Anabolic bulking agent Supports strength increases Supports increased muscle hardness

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Super Mandro by Hard Rock Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Super Mandro label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Super Mandro by Hard Rock Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

3-beta-hydroxy-5-alpha-androst-1-en-17-one

Interacts with
8 drugs
110 mg per serving

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe o...

3-beta-hydroxy-5-alpha-androst-1-en-17-one monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Mandro by Hard Rock Supplements Drug Interactions

Super Mandro contains a single active ingredient, and it has known interactions with 8 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Super Mandro?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

3-beta-hydroxy-5-alpha-androst-1-en-17-one 8

Individual Drug Interactions

The ingredients in Super Mandro interact with 8 drugs. Click any drug to see the details.

1 of the 1 ingredient in Super Mandro interact with drugs. Each result below shows which ingredient is responsible. 3-beta-hydroxy-5-alpha-androst-1-en-17-one

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Mandro with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

3-beta-hydroxy-5-alpha-androst-1-en-17-one1 drug type · 8 drugs

Testosterone

Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.

Likelihood Possible Evidence D
3-beta-hydroxy-5-alpha-androst-1-en-17-one full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Super Mandro, from the product label.

Hard Rock Supplements

See all Hard Rock Supplements products
Name
Hard Rock Supplements
Pharmacist Counseling Corner

Super Mandro by Hard Rock Supplements: Common Questions

Does Super Mandro by Hard Rock Supplements interact with any medications?
Yes. Based on its ingredients, Super Mandro has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Mandro contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Mandro is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Mandro label
Go deeper

The Full Monographs Behind Super Mandro’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

1-androsterone

Interacts with 8 drugs

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It...

Read the full 1-androsterone monograph →
Sources

Sources & How We Checked

Super Mandro's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

1-androsterone 2 references
  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

See these in context on the 1-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team