Interactions on record — worth a quick check against your medications. Based on 4 of 5 ingredients. Check your meds →
Dietary supplement

SuperHD Razor Ingredients & Drug Interactions

by Cellucor

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SuperHD Razor is a dietary supplement by Cellucor with 5 active ingredients. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 1,035 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioperine Black Pepper (Piper nigrum) fruit extract, Synetrim CQ (Cissus quadrangularis) stem and leaf extract, Carnitine Tartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SuperHD Razor by Cellucor

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 5 active ingredients.
  • “SuperHD Razor Blend” is a proprietary blend — the label gives one combined amount (1.61 Gram(s)) without saying how much of each component you get.

SuperHD Razor contains five active ingredients. Thiamine is a B vitamin that supports energy and nerve function.

Black pepper fruit extract (Bioperine) is included as a bioavailability enhancer — it may help your body absorb other compounds. Carnitine tartrate supports cellular energy production.

Cissus quadrangularis stem and leaf extract (Synetrim CQ) is a plant compound, and Tonalin CLA is a conjugated linoleic acid. The capsule is made from gelatin, glycerin, beeswax, and other inactive ingredients like silicon dioxide and colorants.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Weight loss formulation maintain lean muscle reduce body fat.
  • We looked for evidence on: Athletic performance, Cachexia, Exercise-induced muscle damage, Exercise-induced muscle soreness, Fatigue, Muscle preservation — and 3 related terms.
  • The closest evidence on file: Black Pepper is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Black Pepper is rated "Insufficient Reliable Evidence To Rate" for Fatigue.
  • Also on file: Thiamine is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

Thiamine is effective for treating thiamine deficiency and Wernicke-Korsakoff syndrome, a serious neurological condition. It's possibly effective for period pain (dysmenorrhea).

We don't have established effectiveness ratings in our data for black pepper, carnitine tartrate, or Cissus quadrangularis as ingredients in this product formulation. Carnitine tartrate alone is possibly effective for heart failure and high cholesterol, and Cissus quadrangularis is possibly effective for obesity, but evidence for the other uses listed is insufficient.

The evidence for this particular supplement's overall purpose isn't established in the data we hold.

The evidence, ingredient by ingredient Thiamine Black Pepper L-carnitine Cissus Quadrangularis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thiamine is generally very safe by mouth in normal amounts; rare allergic reactions like dermatitis have been reported. Black pepper in food amounts is well tolerated, though concentrated supplements should be used cautiously — burning aftertaste, indigestion, and rarely allergic reactions are possible.

Carnitine tartrate is generally well tolerated at typical doses but can cause stomach upset, nausea, diarrhea, and a fish-like body odor at higher doses. Cissus quadrangularis is well tolerated in short-term use, though long-term safety isn't well studied; headache and insomnia have been reported, but at rates similar to placebo.

Safety data for Tonalin CLA isn't on file. Thiamine is likely safe in pregnancy and lactation when used at recommended supplement amounts under your provider's guidance.

For the other ingredients, pregnancy and breastfeeding safety data is either not available or advises against use — talk with your doctor or pharmacist before taking this product if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Thiamine Black Pepper L-carnitine Cissus Quadrangularis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Black Pepper, Thiamine, L-carnitine, Cissus Quadrangularis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,036 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking SuperHD Razor, double-check if you're on any heart medications (especially propranolol), blood thinners (warfarin or acenocoumarol), diabetes medications, seizure drugs (like phenytoin), HIV antivirals (like nevirapine), tuberculosis drugs (like rifampin), asthma medications (like theophylline), cholesterol drugs (like atorvastatin), thyroid hormone replacement, or immunosuppressants (like cyclosporine). Black pepper can increase blood levels of these drugs; carnitine may amplify blood thinners or reduce thyroid drug effectiveness; and Cissus quadrangularis may lower blood sugar further.

The medication checker on this page can tell you whether your specific drugs interact.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

SuperHD Razor may be worth considering if you're not on medications that interact with its ingredients — thiamine, black pepper, carnitine, and Cissus quadrangularis all have documented interactions with common drugs. If you take heart medications, blood thinners, diabetes drugs, seizure medications, thyroid hormone, or tuberculosis or HIV antivirals, check your exact medications with the tool on this page first.

Anyone pregnant or breastfeeding should talk with their pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SuperHD Razor, straight from the product label.

Brand Cellucor
Barcode (UPC) 842595100242
Net contents 112 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 83121
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SuperHD Razor by Cellucor, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
56
UPC/BARCODE
842595100242
IngredientAmount% DV
Calories15 Calorie(s)--
Calories from Fat10 Calorie(s)--
Total Fat1 Gram(s)2%
Thiamine1 mg67%
Bioperine Black Pepper (Piper nigrum) fruit extract0 NP--
Carnitine Tartrate0 NP--
SuperHD Razor Blend1.6145 Gram(s)--
Tonalin CLA0 NP--
Synetrim CQ (Cissus quadrangularis) stem and leaf extract0 NP--

Other ingredients: Gelatin, Glycerin, Water, Beeswax, Sunflower Lecithin, Silicon Dioxide, Titanium Dioxide, Sorbitol, FD&C Yellow #5, FD&C Blue #1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one serving (2 softgels) twice daily before meals. Do not take two servings (4 softgels) at once, but consume prior to two different meals throughout day. For best results, use for 12 consecutive weeks. Use only as directed.

Precautions

Use only as directed. Warning: This product is only intended to be consumed by healthy adults, 18 years of age or older.

Do not use this product if you are pregnant or nursing. Before using this product, consult with a licensed, qualified, health care professional, including but not limited to, if you are taking any prescription drug or over-the-counter medication, or have any existing medical condition.

Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Discontinue use 2 weeks prior to surgery. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Weight loss formulation Maintain lean muscle and reduce body fat

4 week supply

Made in the U.S.A. using U.S. and imported ingredients and components.

Ignite your goals Extinguish your doubts 104291

You're ready to transform and take your physique to the next level. You need a complete program that takes into account all the variables of burning fat and maintaining lean muscle to accelerate your results. Through years of research and innovation. We've taken our best-selling weight loss product and engineered a system to bring your body into high-definition!

This stimulant free formulation can help promote weight loss by decreasing the number and size of fat cells, decreasing the activity of lipoprotein lipase (LPL) enzymes which help store fats and increasing the rate at which your fat cells disintegrate.

This formulation utilizes natural botanical ingredients that promote the excretion of that excess water, getting you one step closed to that highly-defined and toned physique.

Formula

With clinically studied Tonalin CLA and Synetrim CQ

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Tonalin For reducing body fat Tonalin CLA is an exclusively licensed product of BASF Personal Care and Nutrition GmbH.

Synetrim CQ is a trademark of Icon Group, LLC and is protected under U.S. Patent 7,175,859.

BioPerine is a registered trademark of Sabinsa Corportation.

Cellucor, SuperHD Razor, SuperHD Fire and SuperHD Water are trademarks of and distributed by: Nutrabolt

SuperHD Fire SuperHD Fire is a two-stage daily weight loss formula targeting fat loss, sustained energy, optimized performance and well-being. This potent thermogenic has been designed with the patented, clinically studies on DygloFit have demonstrated that participants who consumed DygloFit for 8 weeks saw reductions in weight, waist size, hip size and body fat percentage. SuperHR Fire is available in both stimulant and stimulant free options to best fit your personalized needs. SuperHR Razor SuperHR Razor was designed with the clinically researched and tested ingredients Tonalin CLA & Synetrim CQ.

Enhance your results by pairing with a thermogenic like SuperHD Fire. SuperHD Water SuperHD Water has been formulated to help you achieve your leanest physique by assisting your body's ability to reduce the temporary accumulation of excess water, which can be caused by stress, physical activity and sodium intake.

Synetrim CQ Multi-patented and clinically tested Synetrim CQ is derived from the botanical Cissus quadrangularis and is the only Cissus quadrangularis extract patented for weight loss. Synetrim CQ can help promote weight loss. Reduce body size, and reduce caloric intake by blocking enzymes that digest carbohydrates and dietary fats. Tonalin CLA Tonalin is the most clinically researched CLA ingredient. Conjugated Linoleic Acid (CLA) is a fatty acid sustainably sourced from natural safflower oil, which is known to improve overall body composition. Tonalin CLA can help achiece body fat reduction and maintain lean muscle development. CLA works in the body in four different ways. CLA decreases the number and size of fat cells, thus lowering body fat mass; decreases the activity of lipoprotein lipase (LPL) enzymes which help to store triglycerides (fats) in fat cells; increases the rate at which fat cells disintegrate; and increases activity of the enzyme carnitine palmitoyltransferase (CPT) so fat is burned up fasted.

General

104595

See for yourself

SuperHD Razor by Cellucor label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SuperHD Razor by Cellucor

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container56 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Thiamine

Interacts with
3 drugs
1 mg per serving Form: Thiamine Mononitrate

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Beeswax, Sunflower Lecithin, Silicon Dioxide, Titanium Dioxide, Sorbitol, FD&C Yellow #5, FD&C Blue #1. These complete the product’s ingredient list but are not active constituents.

Interaction report

SuperHD Razor by Cellucor Drug Interactions

Want to check YOUR meds against SuperHD Razor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,035Drugs
989 Moderate 46 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in SuperHD Razor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioperine Black Pepper (Piper nigrum) fruit extract17 drug types · 1,019 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black pepper might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit platelet aggregation. This has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, black pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of black pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, black pepper might increase blood levels of atorvastatin.
Animal research shows that taking piperine, a constituent of black pepper, 35 mg/kg can increase the maximum serum concentration of atorvastatin three-fold. This has not been reported in humans.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, black pepper might increase the effects and side effects of cyclosporine.
In vitro research shows that piperine, a constituent of black pepper, increases the bioavailability of cyclosporine. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
In vitro research suggests that some constituents of black pepper inhibit CYP2D6. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP3A4.
In vitro research and pharmacokinetic simulation data suggest that piperine, a constituent of black pepper, as well as the pepper fruit seem to inhibit CYP3A4. This has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, black pepper might increase blood levels of lithium due to its diuretic effects. The dose of lithium might need to be reduced.
Black pepper is thought to have diuretic properties.

Likelihood Probable Evidence D
Nevirapine (Viramune)

Black pepper might increase blood levels of nevirapine.
Clinical research shows that piperine, a constituent of black pepper, increases the plasma concentration of nevirapine. However, no adverse effects were observed in this study.

Likelihood Probable Evidence D
P-Glycoprotein Substrates

Theoretically, black pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit P-glycoprotein.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, black pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of black pepper, increases pentobarbital-induced sleeping time.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Black pepper might increase blood levels of phenytoin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption, slow elimination, and increase levels of phenytoin. Taking a single dose of black pepper 1 gram along with phenytoin seems to double the serum concentration of phenytoin. Consuming a soup with black pepper providing piperine 44 mg/200 mL of soup along with phenytoin also seems to increase phenytoin levels when compared with consuming the same soup without black pepper.

Likelihood Possible Evidence B
Propranolol (Inderal)

Black pepper might increase blood levels of propranolol.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of propranolol.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Black pepper might increase blood levels of rifampin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and serum levels of rifampin.

Likelihood Possible Evidence B
Theophylline

Black pepper might increase blood levels of theophylline.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of theophylline.

Likelihood Possible Evidence D
Amoxicillin (Amoxil, Trimox)

Theoretically, black pepper might increase the effects and side effects of amoxicillin.
Animal research shows that taking piperine, a constituent of black pepper, with amoxicillin increases plasma levels of amoxicillin. This has not been reported in humans.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, black pepper might increase blood levels of carbamazepine, potentially increasing the effects and side effects of carbamazepine.
One clinical study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that taking a single 20 mg dose of purified piperine, a constituent of black pepper, increases carbamazepine levels. Piperine may increase carbamazepine absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or inhibiting cytochrome P450 3A4 (CYP3A4) in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects. In vitro research also shows that piperine can increase carbamazepine levels by 11% in a time-dependent manner.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, black pepper might decrease levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research suggests that black pepper induces CYP1A2. This has not been reported in humans.

Likelihood Possible Evidence D

Synetrim CQ (Cissus quadrangularis) stem and leaf extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, Cissus quadrangularis might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies suggest that Cissus quadrangularis might reduce fasting blood glucose in individuals with overweight or obesity.

Likelihood Possible Evidence D

Carnitine Tartrate3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for SuperHD Razor, from the product label.

Cellucor

See all Cellucor products
Name
Nutrabolt
Street Address
3891 S. Traditions Dr.
City
Bryan
State
TX
ZipCode
77807
Phone Number
1.866.927.9686
Web Address
www.cellucor.com
Pharmacist Counseling Corner

SuperHD Razor by Cellucor: Common Questions

Does SuperHD Razor by Cellucor interact with any medications?
Yes. Based on its ingredients, SuperHD Razor has a known interaction with 1,035 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SuperHD Razor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is thiamine in this product for?
Thiamine is a B vitamin that supports energy metabolism and nerve function. It's included in formulas like this one to help your body convert food into energy.
Does SuperHD Razor contain any fillers?
Yes, it has several inactive ingredients in the capsule, including gelatin, glycerin, beeswax, silicon dioxide, and food colorants. These are excipients — they're not active ingredients, but they're necessary for the capsule to hold together and be shelf-stable.
Can I take SuperHD Razor if I'm pregnant?
Thiamine is likely safe in pregnancy at recommended supplement amounts, but the other ingredients in this product — black pepper, carnitine, and especially Cissus quadrangularis — don't have reliable safety data in pregnancy. Talk with your doctor or pharmacist before starting this product.
What's black pepper extract doing in a weight-loss supplement?
Black pepper extract (piperine) is included primarily as a bioavailability enhancer — it may help your body absorb and use the other ingredients more effectively. However, this comes with a trade-off: piperine can also increase blood levels of many medications.
Does this product work for weight loss or body composition?
Cissus quadrangularis is rated possibly effective for obesity, and carnitine is possibly effective for high cholesterol. But the evidence for the overall product's effectiveness for these goals isn't established in the data we hold — you'd need to check clinical trials or talk with your pharmacist about realistic expectations.
What's the fish-like smell I might get from this?
That's a known side effect of carnitine tartrate, especially at higher doses. It comes from a metabolite of carnitine in your body and is harmless, but some people find it bothersome. It usually fades if you stop or lower the dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SuperHD Razor label
Sources

Sources & How We Checked

SuperHD Razor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 82 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thiamine 7 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  4. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
  5. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  6. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
  7. Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.

See these in context on the Thiamine monograph →

Black Pepper 29 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Bano G, Amla V, Raina RK, et al. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Planta Med 1987;53:568-9. PubMed
  4. Bano G, et al. Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol 1991;41;615-7. PubMed
  5. Cohle SD, Trestrail JD III, Graham MA, et al. Fatal pepper aspiration. Am J Dis Child 1988;142:633-6. PubMed
  6. Bhardwaj RK, Glaeser H, Becquemont L, et al. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002;302:645-50. PubMed
  7. Velpandian T, Jasuja R, Bhardwaj RK, et al. Piperine in food: interference in the pharmacokinetics of phenytoin. Eur J Drug Metab Pharmacokinet 2001;26:241-7. PubMed
  8. Pattanaik S, Hota D, Prabhakar S, et al. Pharmacokinetic interaction of a single dose of piperine with steady-state carbamazepine in epilepsy patients. Phytother Res 2009;23:1281-6.
  9. Munakata, M., Kobayashi, K., Niisato-Nezu, J., Tanaka, S., Kakisaka, Y., Ebihara, T., Ebihara, S., Haginoya, K., Tsuchiya, S., and Onuma, A. Olfactory stimulation using black pepper oil facilitates oral feeding in pediatric patients receiving long-term en
  10. Myers, B. M., Smith, J. L., and Graham, D. Y. Effect of red pepper and black pepper on the stomach. Am J Gastroenterol 1987;82(3):211-214.
  11. Raghavendra, R. H. and Naidu, K. A. Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis. Prostaglandins Leukot.Essent.Fatty Acids 2009;81(1):73-78. PubMed
  12. Subehan, Usia, T., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum. Planta Med 2006;72(6):527-532.
  13. Kasibhatta, R. and Naidu, M. U. Influence of piperine on the pharmacokinetics of nevirapine under fasting conditions: a randomised, crossover, placebo-controlled study. Drugs R.D. 2007;8(6):383-391. PubMed
  14. Usia, T., Iwata, H., Hiratsuka, A., Watabe, T., Kadota, S., and Tezuka, Y. CYP3A4 and CYP2D6 inhibitory activities of Indonesian medicinal plants. Phytomedicine. 2006;13(1-2):67-73. PubMed
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L-carnitine 41 references
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Cissus Quadrangularis 5 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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