Ubiquinol Ingredients & Drug Interactions
by Dr. Mercola
What is this page for?
First and foremost: checking Ubiquinol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ubiquinol is a dietary supplement by Dr. Mercola with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ubiquinol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ubiquinol by Dr. Mercola
Ask about any prescription or over-the-counter medication and we check it for interactions with Ubiquinol by Dr. Mercola — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ubiquinol by Dr. Mercola
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: ubiquinol, the reduced form of coenzyme Q10 (CoQ10), a compound your body makes naturally and uses for energy production in your cells. The liquid formulation also includes medium chain triglycerides, silicon dioxide, and mixed tocopherols as inactive ingredients.
Does it work?
Not established
Coenzyme Q10 is likely effective for treating coenzyme Q10 deficiency itself. For other conditions — fibromyalgia, migraine headaches, congestive heart failure, and diabetic nerve pain — the evidence is rated possibly effective, meaning some clinical research supports benefit but more study is needed.
The data we hold doesn't establish effectiveness for other uses.
How safe is it?
Well-documented data
Orally, coenzyme Q10 is generally well tolerated. In clinical trials, no serious adverse effects have been reported.
Gastrointestinal side effects such as nausea, diarrhea, heartburn, and appetite loss may occur, but these happen in less than 1% of people and can often be minimized by dividing doses above 100 mg throughout the day. Headache, dizziness, insomnia, and rarely skin itching or allergic rash have been reported.
There isn't enough reliable safety data during pregnancy, so it's best to avoid it unless your doctor advises otherwise. Safety data on breastfeeding hasn't been well studied — talk with your doctor or pharmacist before using this product if you're nursing.
Meds to double-check
Moderate interaction found
Before starting this product, double-check with your doctor or pharmacist if you take warfarin or other blood thinners (Moderate concern) — coenzyme Q10 may reduce how well they work. If you're undergoing chemotherapy, particularly with alkylating agents like cyclophosphamide, discuss this with your oncologist, as coenzyme Q10 could theoretically interfere with how the drugs work (Moderate concern).
If you take blood pressure medications, mention this product because coenzyme Q10 might add to their blood-pressure-lowering effect (Minor concern).
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Ubiquinol may be worth considering if you have a documented coenzyme Q10 deficiency or are interested in its possibly effective uses like migraine or heart failure — but if you take blood thinners like warfarin, chemotherapy drugs, or blood pressure medications, you need to check with your own doctor or pharmacist first. It's generally well tolerated, though mild stomach upset can happen.
Your healthcare provider can help you decide if it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ubiquinol, straight from the product label.
| Brand | Dr. Mercola |
|---|---|
| Barcode (UPC) | 810487031929 |
| Net contents | 1.6 fl. Oz.; 48 mL |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 232940 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ubiquinol by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Ubiquinol | 100 mg | -- |
Other ingredients: Medium Chain Triglycerides, Silicon Dioxide, Mixed Tocopherols
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Supports mitochondrial health
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: Adults, as a dietary supplement, dispense product directly onto food. Dispense 10 pumps for 100 mg of ubiquibol. Before using this pump for the first time, remove the cap and prime the pump by repeatedly pressing until liquid appears. Prime the pump over a sink or covered surface. 15 pumps provides 150 mg of ubiquinol.
Precautions
Keep out of reach of children.
Do not use if safety seal is broken.
If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.
General Statements
Dr. Mercola has been providing quality products since 2001.
Made in Canada
Brand IP Statement(s)
Q+, Kaneka Ubiquinol and the quality seal are registered or pending trademarks of Kaneka Corp.
Seals/Symbols
Made with Quality Q+ Kaneka Ubiquinol
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ubiquinol by Dr. Mercola label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ubiquinol by Dr. Mercola
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 mL Dosage formLiquid Servings per container24 Amounts shown are per serving.
Ubiquinol
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Ubiquinol monograph & interactionsOther (inactive) ingredients: Medium Chain Triglycerides, Silicon Dioxide, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.
Ubiquinol by Dr. Mercola Drug Interactions
HelloPharmacist Interaction Report
Dr.
Mercola's Ubiquinol can interact with several medication types. Through its coenzyme Q10 content, the most serious concern is with blood thinners like warfarin (Coumadin) — coenzyme Q10 may reduce warfarin's ability to prevent clots, and a handful of cases of decreased warfarin effectiveness have been reported.
Read the full breakdown — every affected drug type, severity by severity
Chemotherapy drugs, particularly alkylating agents such as cyclophosphamide, may also be affected. Because coenzyme Q10 is an antioxidant, it could theoretically reduce how well these cancer drugs work, since many chemotherapy drugs depend on creating free radicals to kill tumor cells.
Blood pressure medications are a minor concern; coenzyme Q10 might add to their effect and lower your blood pressure further than intended.
Additionally, if you take any of these medication types — blood thinners, chemotherapy, or blood pressure drugs — run your specific medications through the interaction checker on this page before starting. Altogether, these interactions span 198 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ubiquinol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ubiquinol interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ubiquinol interact with drugs. Each result below shows which ingredient is responsible. Ubiquinol
Hydroflumethiazide, ReserpineSalutensin, Salutensin-Demi
How Hydroflumethiazide, Reserpine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Hydroflumethiazide, Reserpine interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Iloprost interactionIndapamideLozide, Lozol
How Indapamide interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Indapamide interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Irbesartan interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Irbesartan, Hydrochlorothiazide interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Isosorbide Dinitrate, Hydralazine interactionIsradipineDynacirc CR
How Isradipine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Isradipine interactionLabetalolNormodyne, Trandate
How Labetalol interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Labetalol interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Lercanidipine Hydrochloride interactionLevamlodipineConjupri
How Levamlodipine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Levamlodipine interactionLisinoprilPrinivil, Qbrelis, Zestril
How Lisinopril interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Lisinopril interactionLosartan PotassiumCozaar
How Losartan Potassium interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Losartan Potassium interactionMacitentanOpsumit
How Macitentan interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Macitentan interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Macitentan, Tadalafil interactionMannitolBronchitol, Osmitrol
How Mannitol interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Mannitol interactionMecamylamineInversine
How Mecamylamine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Mecamylamine interactionMethazolamideNeptazane
How Methazolamide interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Methazolamide interactionMethyclothiazideAquatensen, Enduron
How Methyclothiazide interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Methyclothiazide interactionMethyclothiazide, PargylineEutron
How Methyclothiazide, Pargyline interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Methyclothiazide, Pargyline interactionMethyclothiazide, ReserpineDiutensen-R
How Methyclothiazide, Reserpine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Methyclothiazide, Reserpine interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Methyldopa interactionMetolazoneDiulo, Mykrox, Zaroxolyn
How Metolazone interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Metolazone interactionMetoprololLopressor, Toprol XL
How Metoprolol interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Metoprolol interactionMinoxidilLoniten, Minoxidil, Rogaine
How Minoxidil interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Minoxidil interactionMoexiprilUnivasc
How Moexipril interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Moexipril interactionMoxonidinePhysiotens
How Moxonidine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Moxonidine interactionNadololCorgard, Nadolol
How Nadolol interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Nadolol interactionNebivololBystolic, Nebilet
How Nebivolol interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Nebivolol interactionNebivolol Hydrochloride, ValsartanByvalson
How Nebivolol Hydrochloride, Valsartan interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Nebivolol Hydrochloride, Valsartan interactionNicardipineCardene, Cardene IV, Cardene SR
How Nicardipine interacts with Ubiquinol — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Nicardipine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ubiquinol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ubiquinol
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Ubiquinol, from the product label.
Dr. Mercola
See all Dr. Mercola products- Name
- NHP
- Street Address
- 125 SW 3rd Place
- City
- Cape Coral
- State
- FL
- ZipCode
- 33991
- Phone Number
- (877) 985-2696
Ubiquinol by Dr. Mercola: Common Questions
Does Ubiquinol by Dr. Mercola interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is ubiquinol, and why is it in this product?
Does this product actually work?
Will this upset my stomach?
Is this safe to take while I'm breastfeeding?
Can I take this with my current medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ubiquinol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ubiquinol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ubiquinol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
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