FDA-filed SPL labeling · retrieved through openFDA

Clindamycin

Clindamycin is an antibiotic used to treat serious bacterial infections when other antibiotics aren't a good fit.

Brand names CleocinClindaCureAntirobeZydaclinClinda-Guard +11 more
Drug classes ⓘ Decreased Sebaceous Gland Activity
Rx Forms 8 Routes Oral · Intravenous · Topical · Intramuscular; Intravenous +2
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 104 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveSep 25, 2020
Clinical labels in scope ⓘ104
AvailabilityRx
Earliest approval/marketing year ⓘ1970
FDA-listed product records ⓘ600
Boxed warningYes
How we combine label and product data →
Other forms & routes:
Injection Topical Vaginal
⭐ Clindamycin at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Clindamycin is a powerful antibiotic reserved for serious infections — it comes with a real warning about a dangerous gut infection (C. diff), so it's not a first-choice drug for everyday illnesses. Always take it with a full glass of water, finish the complete course, and call your doctor immediately if you develop severe diarrhea, a serious skin reaction, or signs of an allergic response. The benefits are real when you need it, but it deserves to be taken seriously.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

Important warning: Clindamycin can cause a dangerous intestinal infection called C. diff colitis. Nearly all antibiotics — including clindamycin — can disturb the healthy bacteria in your colon and allow a harmful germ called Clostridioides difficile (C. diff) to take over. C. diff releases toxins that can cause severe inflammation of the colon. This ranges from mild diarrhea to a potentially fatal condition. Some strains of C. diff are especially hard to treat and may even require surgery to remove part of the colon.

Watch for: diarrhea that is severe, persistent, bloody, or watery — during treatment or even weeks to months after you finish the antibiotic. Because of this risk, clindamycin should only be used for serious infections when safer alternatives aren't suitable. It should not be used for routine viral infections like colds or most sore throats.

Read the full warning on DailyMed →

📖 Clindamycin: Patient Information Guide

A plain-language walkthrough of Clindamycin — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Clindamycin treats serious bacterial infections that other antibiotics may not cover — particularly for people who can't take penicillin.

  • Lung and respiratory infections: pneumonia caused by anaerobic bacteria, lung abscess, fluid infection around the lungs (empyema)
  • Skin and soft tissue infections: serious skin infections caused by streptococci, staphylococci, or anaerobic bacteria
  • Bloodstream infections (septicemia): serious bacterial infections in the blood
  • Abdominal infections: peritonitis (infection of the abdominal lining) and abdominal abscesses
  • Female pelvic and reproductive infections: endometritis (uterine lining infection), pelvic cellulitis, tubo-ovarian abscess, and post-surgical vaginal infections
⚙️How it works▾

Clindamycin targets a specific component of the bacterial ribosome — the 50S subunit — and binds to its 23S RNA. The ribosome is the machinery bacteria use to build proteins essential for their survival and reproduction. By blocking this process, clindamycin stops bacteria from multiplying. It is classified as bacteriostatic, meaning it halts bacterial growth rather than directly killing the bacteria, giving your immune system the upper hand.

It works best against anaerobic bacteria (those that live without oxygen) and certain types of gram-positive bacteria including streptococci, staphylococci, and pneumococci. Lab testing is recommended to confirm that the specific bacteria causing your infection are actually susceptible to clindamycin before or during treatment.

💊How it's taken▾

Clindamycin capsules are taken by mouth several times daily — generally every 6 hours. Always swallow each capsule with a generous amount of water (at least a full glass) and remain upright for at least 30 minutes after taking it to prevent irritation to your esophagus. Food does not significantly affect how the drug is absorbed, so you can take it with or without a meal.

  • Take doses at evenly spaced intervals to keep steady levels in your system
  • For strep throat or strep infections, treatment typically continues for at least 10 days
  • Capsules are not appropriate for children who cannot swallow them whole — a liquid formulation exists for those patients
  • If you develop significant diarrhea during treatment, contact your doctor before stopping on your own
🤒Side effects — in detail▾

The most common side effects involve the digestive system, but there are some reactions that require prompt medical attention.

  • Diarrhea — common and sometimes a warning sign of something more serious
  • Nausea or vomiting
  • Abdominal pain or cramping
  • Metallic or unpleasant taste in the mouth
  • Skin rash (usually mild, maculopapular — small flat or raised spots)
  • Vaginal irritation or itching
  • Itching (pruritus)
  • Abnormal liver enzyme levels on blood tests; rarely, yellowing of skin or eyes (jaundice)

Seek immediate care for severe or bloody diarrhea, signs of a serious allergic reaction (throat swelling, difficulty breathing, chest pain), severe blistering skin reactions, or significant decrease in urination — these can signal rare but life-threatening complications.

⚠️Warnings & precautions▾
  • C. diff colitis: The most critical risk. Clindamycin can disrupt gut bacteria and allow Clostridioides difficile (C. diff) to overgrow, causing severe colitis (colon inflammation) that can be fatal. This can appear during treatment or up to 2 months after. Watery, bloody, or persistent diarrhea needs immediate medical evaluation.
  • Severe allergic reactions: Anaphylaxis, dangerous skin conditions (toxic epidermal necrolysis, Stevens-Johnson syndrome, DRESS), and even heart-related events have been reported. If you develop severe rash, blistering skin, or any signs of anaphylaxis, stop the medication and seek emergency care.
  • Kidney injury: Clindamycin can potentially harm the kidneys, especially in people who already have reduced kidney function or who take other medications that affect the kidneys. Monitoring may be needed.
  • Not for viral infections: Clindamycin does not work against viruses (colds, flu, most sore throats) and should never be used for them.
  • Brain/spinal fluid limitation: Clindamycin does not reach meaningful levels in cerebrospinal fluid, so it cannot be used to treat meningitis (brain/spinal cord infections).
🔀What it interacts with▾

Clindamycin has a few notable drug interactions that could affect how well it works or increase side effect risk.

  • Neuromuscular blocking agents (muscle relaxants): Clindamycin can enhance their muscle-paralysis effects — important to know before surgery or procedures.
  • Strong CYP3A4 inhibitors (e.g., certain antifungals, some HIV medications): These slow the breakdown of clindamycin in the liver, raising its levels in your blood and potentially increasing side effects. Extra monitoring may be needed.
  • Strong CYP3A4 inducers (e.g., rifampicin): These speed up the breakdown of clindamycin, potentially lowering its levels enough that it stops working effectively. Your doctor should monitor for loss of effectiveness.

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Allergy to clindamycin or lincomycin: Do not take this medication if you've had a previous hypersensitivity reaction to either — this is a firm contraindication.
  • History of bowel or digestive conditions: Tell your doctor, especially if you've had colitis or other serious gut problems in the past.
  • Kidney or liver problems: The drug clears more slowly in people with significantly reduced kidney or liver function. Your doctor should know about any existing impairment, though dosage adjustments are generally not required.
  • Older adults: The drug may stay in the body a bit longer in elderly patients. No routine dose change is required, but it's worth flagging.
  • Children: The capsule form is only for children who can swallow capsules whole. Younger or smaller children should use the liquid (oral solution) instead.
  • All other medications: Share your complete medication list — especially muscle relaxants, rifampicin, or any antifungals — due to interaction risks.
🚑If you take too much▾

There is no well-defined overdose treatment specific to clindamycin. Animal studies suggest that very high doses can cause seizures and severe central nervous system depression. Hemodialysis (kidney dialysis) is not effective at removing clindamycin from the blood, so it cannot be used to speed up clearance. If you suspect an overdose, contact Poison Control or seek emergency care immediately.

📡Pharmacodynamics — effects in the body▾

Clindamycin is bacteriostatic — it inhibits bacterial growth rather than directly killing bacteria. It does this by blocking protein synthesis inside the bacterial cell, preventing bacteria from making the proteins they need to survive and reproduce. This mechanism is specific to bacteria; it does not affect human cells the same way. Effective blood levels (above the minimum inhibitory concentration for target bacteria) are maintained for at least 6 hours after each dose with standard dosing.

🔬Pharmacokinetics — how your body processes it▾

When taken by mouth, clindamycin is rapidly and almost completely absorbed — about 90% of the dose reaches your bloodstream, and food does not significantly change this. Peak blood levels are reached within about 45 minutes of an oral dose. The drug is widely distributed throughout the body, including into bones and soft tissues, but it does not reach significant levels in cerebrospinal fluid (the fluid around the brain and spine).

Clindamycin is broken down mainly by a liver enzyme called CYP3A4 and cleared from the body with an average half-life (the time for blood levels to drop by half) of about 2.4–3 hours in adults, and around 4 hours in older adults. Only a small fraction is excreted through the urine and stool; the rest leaves the body as inactive breakdown products. Dialysis does not effectively remove this drug from the bloodstream.

📦How to store it▾

Store at controlled room temperature 20° to 25° C (68° to 77° F) .

📄 Written from Clindamycin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

169

Supplements & herbs that interact with Clindamycin

169 supplements and herbal products have documented interactions with Clindamycin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 3
  • Moderate · 123
  • Minor · 43
ACTIVATED CHARCOAL Major GRAPEFRUIT Major ST. JOHN'S WORT Major ACACIA RIGIDULA Moderate ADRAFINIL Moderate AFRICAN WILD POTATO Moderate AMERICAN ELDER Moderate ASTAXANTHIN Moderate +161 more
Every supplement checked against Clindamycin — ranked by severity The full interaction hub: 3 major · 123 moderate · 43 minor · every one linked to its full report. Check Clindamycin against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

7

Nutrient depletion considerations

Clindamycin has been associated with lower levels of 7 nutrients in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

Evidence & significance mix
  • Higher significance · 6
  • Moderate · 1
BIOTIN Insignificant Depletion FOLIC ACID Insignificant Depletion RIBOFLAVIN Insignificant Depletion THIAMINE Insignificant Depletion VITAMIN B12 Insignificant Depletion VITAMIN B6 Insignificant Depletion VITAMIN K Moderate Depletion
See the full Clindamycin nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Clindamycin — the kind of thing our pharmacy team would talk through with you at the counter.

What kinds of infections is clindamycin actually used for? ▾
Clindamycin is used for serious bacterial infections — things like deep skin infections, lung abscesses, pelvic infections, and abdominal infections. It's often chosen when penicillin-type antibiotics aren't an option, such as if you have a penicillin allergy. It's a heavier-duty antibiotic, so doctors reserve it for cases where simpler options won't work. It does nothing against viruses like colds or the flu.
Do I need to take clindamycin with food? ▾
You don't have to eat with it — food doesn't meaningfully change how it's absorbed. But the most important thing is to take each capsule with a full, large glass of water, and stay upright (don't lie down) for at least 30 minutes afterward. This helps prevent the capsule from sitting in your esophagus and causing irritation or ulceration, which has been reported.
What's the diarrhea warning I keep hearing about? ▾
This is a real and important one. Clindamycin can disrupt the normal bacterial balance in your gut, sometimes allowing a harmful germ called C. diff to take over. C. diff can cause anything from mild diarrhea to a severe, dangerous colon infection. The tricky part is it can happen during treatment or even up to two months after you finish the antibiotic. If your diarrhea is severe, bloody, or just doesn't quit, call your doctor right away — don't wait.
What side effects are most common and which ones should I call about? ▾
The most common ones are digestive — nausea, stomach cramps, diarrhea, and sometimes a metallic taste in your mouth. Mild skin rash is also fairly common. Those are worth mentioning at your next visit but aren't usually emergencies. What you should call about right away: severe or bloody diarrhea, signs of a bad allergic reaction (swelling of your face or throat, trouble breathing, chest pain), severe blistering or peeling skin, or yellowing of your skin or eyes.
Are there any medications I should avoid while taking this? ▾
Yes — a few are worth mentioning to your doctor. If you're taking any muscle relaxants (especially ones used in surgical settings), clindamycin can make their effects stronger. Certain medications that affect liver enzymes — like rifampicin, some antifungals, or some HIV medications — can either raise clindamycin levels too high or drop them too low. Always share your full medication list with your prescriber or pharmacist before starting.
Can I stop taking it once I start feeling better? ▾
It's really important that you finish the full course, even if you feel completely better after a few days. Stopping early can allow the infection to come back, and sometimes those returning bacteria are harder to treat. If your infection involves strep bacteria, treatment needs to continue for at least 10 days. If you're having trouble tolerating it — especially because of diarrhea — call your doctor before stopping on your own.
Is Clindamycin available over the counter? ▾
Clindamycin is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Clindamycin first available? ▾
Clindamycin has been available in the United States since at least 1970, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Clindamycin? ▾
Clindamycin is supplied by 112 manufacturers listed in the FDA NDC Directory, including Bryant Ranch Prepack, Pharmacia & Upjohn Company LLC, A-S Medication Solutions.

💬 Answers drafted from Clindamycin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

📊Clindamycin supplement interactions169 checked — ranked by severity 🌿Drug & Supplement CheckerClindamycin vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Clindamycin NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

💊 How Clindamycin comes

Clindamycin is available in 8 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Capsule

By mouth
Brands Cleocin Hydrochloride
Available strengths 3 strengths
75 mg 150 mg 300 mg
257 FDA-listed product records ⓘ

Topical solution

On the skin
Available strengths 2 strengths
10 mg/mL 11.9 mg/mL
49 FDA-listed product records ⓘ

Oral solution

By mouth
Brands Clindamycin Palmitate Hydrochloride
Available strengths 2 strengths
75 mg/5 mL 75 mg/kg
31 FDA-listed product records ⓘ

Vaginal cream or gel

Vaginal
Brands Cleocin Clindesse Xaciato
Available strengths 2 strengths
20 mg/g 100 mg/5 g
13 FDA-listed product records ⓘ

Inhaler

On the skin
Brands Evoclin
Available strengths 1 strength
10 mg/g
10 FDA-listed product records ⓘ

Vaginal insert

Vaginal
Brands Cleocin
Available strengths 1 strength
100 mg
2 FDA-listed product records ⓘ

📊 Clindamycin across the U.S. market

How Clindamycin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

8
Dose forms ⓘ
112
Manufacturers
20
Brand names
600
FDA-listed product records ⓘ
1970
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (35) · Kit (2) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Bryant Ranch Prepack12%
Pharmacia & Upjohn Company LLC8%
A-S Medication Solutions7%
Medical Purchasing Solutions, LLC6%
Baxter Healthcare Corporation5%
NuCare Pharmaceuticals,Inc.5%
Other makers57%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Clindamycin is used

A general measure of how commonly Clindamycin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Clindamycin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

3,018,439
Medicaid prescriptions filled (Q1–Q4 2025)
$84.8M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Clindamycin prescribed? Of the 1,596 medications we measure, Clindamycin ranks #74 by Medicaid prescriptions — more than 95% of them.

Where Clindamycin ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #74 of 1,596
#69 Divalproex 3,122,967 Rx #70 Tirzepatide injection 3,083,095 Rx #71 Tirzepatide 3,083,095 Rx #72 Levetiracetam 3,055,070 Rx #73 Oxycodone 3,037,434 Rx #74 Clindamycin 3,018,439 Rx #75 Hydrocortisone Topical 2,941,220 Rx #76 Mupirocin 2,929,179 Rx #77 Empagliflozin 2,905,773 Rx #78 Venlafaxine 2,819,501 Rx #79 Propranolol (Infantile... 2,801,185 Rx

Utilization by Clindamycin product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 300 mg oral capsule is the most-dispensed Clindamycin product — about 28% of these Medicaid prescriptions.

clindamycin 300 MG Oral Capsule Most dispensed

831,096 Medicaid prescriptions (Q1–Q4 2025) 28% of Clindamycin prescriptions shown $10M gross reimbursement (before rebates) ≈ $12 per prescription (gross)

Summed across the 8 of 347 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 284215

clindamycin 10 MG/ML Topical Solution

528,845 Medicaid prescriptions (Q1–Q4 2025) 18% of Clindamycin prescriptions shown $11.4M gross reimbursement (before rebates) ≈ $22 per prescription (gross)

Summed across the 18 of 46 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309333

Twice-Daily clindamycin 0.01 MG/MG Topical Gel

510,626 Medicaid prescriptions (Q1–Q4 2025) 17% of Clindamycin prescriptions shown $11M gross reimbursement (before rebates) ≈ $22 per prescription (gross)

Summed across the 22 of 44 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2676585

clindamycin 10 MG/ML Topical Lotion

416,215 Medicaid prescriptions (Q1–Q4 2025) 14% of Clindamycin prescriptions shown $12.4M gross reimbursement (before rebates) ≈ $30 per prescription (gross)

Summed across the 7 of 13 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197519

clindamycin 150 MG Oral Capsule

248,121 Medicaid prescriptions (Q1–Q4 2025) 8% of Clindamycin prescriptions shown $2.9M gross reimbursement (before rebates) ≈ $12 per prescription (gross)

Summed across the 10 of 321 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197518

clindamycin 10 MG/ML Medicated Pad

232,174 Medicaid prescriptions (Q1–Q4 2025) 8% of Clindamycin prescriptions shown $6.4M gross reimbursement (before rebates) ≈ $27 per prescription (gross)

Summed across the 4 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 797274

clindamycin 15 MG/ML Oral Solution

129,993 Medicaid prescriptions (Q1–Q4 2025) 4% of Clindamycin prescriptions shown $7.4M gross reimbursement (before rebates) ≈ $57 per prescription (gross)

Summed across the 8 of 18 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 562266

clindamycin 20 MG/ML Vaginal Cream

71,273 Medicaid prescriptions (Q1–Q4 2025) 2% of Clindamycin prescriptions shown $4.9M gross reimbursement (before rebates) ≈ $69 per prescription (gross)

Summed across the 4 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309337

Once-Daily clindamycin 0.01 MG/MG Topical Gel

29,363 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $16.3M gross reimbursement (before rebates) ≈ $554 per prescription (gross)

Summed across the 4 of 6 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309332

50 ML clindamycin 18 MG/ML Injection

6,171 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $474,301 gross reimbursement (before rebates) ≈ $77 per prescription (gross)

Summed across the 6 of 13 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309336

50 ML clindamycin 12 MG/ML Injection

4,501 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $209,101 gross reimbursement (before rebates) ≈ $46 per prescription (gross)

Summed across the 6 of 13 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309335

clindamycin 100 MG Vaginal Insert

3,594 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $884,867 gross reimbursement (before rebates) ≈ $246 per prescription (gross)

Summed across the 1 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 259233

clindamycin 0.02 MG/MG Vaginal Gel

1,748 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $275,665 gross reimbursement (before rebates) ≈ $158 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2587810

clindamycin 10 MG/ML Topical Foam

1,563 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $347,986 gross reimbursement (before rebates) ≈ $223 per prescription (gross)

Summed across the 7 of 9 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 477451

4 ML clindamycin 150 MG/ML Injection

1,051 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $12,355 gross reimbursement (before rebates) ≈ $12 per prescription (gross)

Summed across the 3 of 12 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737578

2 ML clindamycin 150 MG/ML Injection

708 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $5,496 gross reimbursement (before rebates) ≈ $7.76 per prescription (gross)

Summed across the 2 of 13 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737244

clindamycin 75 MG Oral Capsule

705 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $14,282 gross reimbursement (before rebates) ≈ $20 per prescription (gross)

Summed across the 1 of 21 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309329

50 ML clindamycin 6 MG/ML Injection

347 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $1,869 gross reimbursement (before rebates) ≈ $5.39 per prescription (gross)

Summed across the 2 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 309339

6 ML clindamycin 150 MG/ML Injection

309 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $20,812 gross reimbursement (before rebates) ≈ $67 per prescription (gross)

Summed across the 2 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737581

clindamycin 150 MG/ML Injectable Solution

36 Medicaid prescriptions (Q1–Q4 2025) <1% of Clindamycin prescriptions shown $181 gross reimbursement (before rebates) ≈ $5.02 per prescription (gross)

Summed across the 1 of 24 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 205964

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Clindamycin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 117 of 940 listed Clindamycin NDCs with Medicaid activity.

🔍 Compare Clindamycin products

A representative set of FDA-listed product records for Clindamycin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 200 of 600 products — FDA National Drug Code Directory. See every product, package size and price: browse all 600 Clindamycin NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Clindamycin RxCUI 2582 15 dose forms · 27 strengths
  1. Dose form (SCDF) Injectable Solution RxCUI 371557 In current FDA listings
    Clinical drug / strength (SCD) 150 MG/ML RxCUI 205964
  3. Dose form (SCDF) Medicated Pad RxCUI 797273 No current FDA listing
    Clinical drug / strength (SCD) 10 MG/ML RxCUI 797274
  4. Dose form (SCDF) Oral Capsule RxCUI 371555 In current FDA listings
    Clinical drug / strength (SCD) 25 MG RxCUI 853019 75 MG RxCUI 309329 150 MG RxCUI 197518 300 MG RxCUI 284215
  5. Dose form (SCDF) Oral Solution RxCUI 562265 In current FDA listings
    Clinical drug / strength (SCD) 15 MG/ML RxCUI 562266 25 MG/ML RxCUI 900424
  6. Dose form (SCDF) Oral Suspension RxCUI 371556 No current FDA listing
    Clinical drug / strength (SCD) 75 MG/ML RxCUI 392275
  7. Dose form (SCDF) Oral Tablet RxCUI 438689 No current FDA listing
    Clinical drug / strength (SCD) 25 MG RxCUI 900391 75 MG RxCUI 900460 150 MG RxCUI 433773
  8. Dose form (SCDF) Topical Cream RxCUI 379276 In current FDA listings
    Clinical drug / strength (SCD) 20 MG/ML RxCUI 141970
  9. Dose form (SCDF) Topical Foam RxCUI 477452 In current FDA listings
    Clinical drug / strength (SCD) 10 MG/ML RxCUI 477451
  11. Dose form (SCDF) Topical Lotion RxCUI 377650 In current FDA listings
    Clinical drug / strength (SCD) 10 MG/ML RxCUI 197519
  12. Dose form (SCDF) Topical Solution RxCUI 377481 In current FDA listings
    Clinical drug / strength (SCD) 10 MG/ML RxCUI 309333
  13. Dose form (SCDF) Vaginal Cream RxCUI 377651 In current FDA listings
    Clinical drug / strength (SCD) 20 MG/ML RxCUI 309337
  14. Dose form (SCDF) Vaginal Gel RxCUI 2587809 In current FDA listings
    Clinical drug / strength (SCD) 0.02 MG/MG RxCUI 2587810
  15. Dose form (SCDF) Vaginal Insert RxCUI 2109113 In current FDA listings
    Clinical drug / strength (SCD) 100 MG RxCUI 259233

Look up RxCUI 2582 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Cleocin ClindaCure Antirobe Zydaclin Clinda-Guard Xaciato Clindagel Clindamax Evoclin Clindesse Cleocin-T Clintabs Cleocin Phosphate Clindamycin Palmitate Hydrochloride Clindamycin in 5 Percent Dextrose Cleocin Hydrochloride

🏭 Manufacturers & labelers

Bryant Ranch Prepack 57 Pharmacia & Upjohn Company LLC 38 A-S Medication Solutions 32 Medical Purchasing Solutions, LLC 27 Baxter Healthcare Corporation 22 NuCare Pharmaceuticals,Inc. 22 Remedyrepack Inc. 14 Padagis Israel Pharmaceuticals Ltd 13 PD-Rx Pharmaceuticals, Inc. 12 Aurobindo Pharma Limited 12 RPK Pharmaceuticals, Inc. 11 Denton Pharma, Inc. DBA Northwind Pharmaceuticals 10 Glenmark Pharmaceuticals Inc., Usa 10 Sandoz Inc 9 St. Mary's Medical Park Pharmacy 9 Greenstone LLC 9 Proficient Rx LP 9 Northstar Rx Llc 8 Direct Rx 8 Medimetriks Pharmaceuticals, Inc. 8 Zydus Lifesciences Limited 8 Baxter Healthcare Company 8 RedPharm Drug, Inc. 8 Sun Pharmaceutical Industries, Inc. 8

…and 16 more on the FDA NDC directory.

RxNorm drug class

Clindamycin belongs to the Lincosamide Antibacterial class.

Pharmacologic class Lincosamide Antibacterial
Drug family (ATC) Antiinfectives for treatment of acne, Antibiotics, Lincosamides

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Sep 25, 2020
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Clindamycin.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Clindamycin after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
104
NDC products indexed
600
Distinct labelers/manufacturers represented
112
Linked representative label ⓘ
Clinical Solutions Wholesale, LLC
Linked label effective
Sep 25, 2020
Composite sections available
19
Linked SPL Set ID
aed859b1-f886-4e14-b7eb-c948617c0188
Linked SPL Document ID
b025101a-bf75-578a-e053-2a95a90aa61a
Open the linked representative label on DailyMed ↗
NDC package records associated with this linked SPL 1

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 104 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Clinical Solutions Wholesale, LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.