Levetiracetam
Levetiracetam is an antiepileptic (anti-seizure) medicine used to treat partial-onset seizures, myoclonic seizures in juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures across multiple oral and intravenous formulations.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 141 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
📖 Levetiracetam: Patient Information Guide
A plain-language walkthrough of Levetiracetam — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.
🎯What it's used for▾
Levetiracetam is an antiepileptic drug approved to treat several types of seizures. Approved uses depend on the specific product, formulation, age, and weight of the patient.
- Partial-onset seizures: Keppra oral, Roweepra tablets, Levetiracetam oral solution, and Levetiracetam injection treat partial-onset seizures in patients 1 month and older. Spritam and levetiracetam tablets for oral suspension treat partial-onset seizures in patients 4 years and older weighing more than 20 kg. Elepsia XR, Keppra XR, and Levetiracetam ER extended-release tablets treat partial-onset seizures as add-on therapy in patients 12 years and older.
- Myoclonic seizures in juvenile myoclonic epilepsy: Keppra oral, Roweepra, Spritam, Levetiracetam oral and injectable forms are approved as add-on therapy for myoclonic seizures in patients 12 years and older. Levetiracetam in Sodium Chloride injection is approved for adults (16 years and older) when oral dosing is not feasible.
- Primary generalized tonic-clonic seizures: Keppra oral, Roweepra, Spritam, Levetiracetam oral and injectable forms are approved as add-on therapy for primary generalized tonic-clonic seizures in patients 6 years and older with idiopathic generalized epilepsy. Levetiracetam in Sodium Chloride injection is approved for this use in adults (16 years and older) when oral dosing is temporarily not feasible.
- Injectable levetiracetam products are for intravenous use only, as a temporary substitute when oral therapy is not possible.
⚙️How it works▾
The exact way levetiracetam prevents seizures is not fully known. Research shows it binds to a specific protein on nerve cells in the brain called SV2A (synaptic vesicle protein 2A). This protein is believed to help regulate how chemical signals are released between nerve cells. By attaching to SV2A, levetiracetam is thought to reduce the excessive, disorganized electrical firing in the brain that causes seizures. Studies show that the stronger a related compound binds to SV2A, the better it works against seizures — supporting the idea that this interaction is central to how the drug works.
💊How it's taken▾
How levetiracetam is taken depends on the specific product and the patient's age and weight. Immediate-release oral forms (tablets and solution) are generally taken twice daily. Extended-release tablets — including Elepsia XR, Keppra XR, and Levetiracetam ER — are taken once daily and must be swallowed whole; do not chew, crush, or break them. Spritam tablets are placed on the tongue with a sip of liquid and allowed to disintegrate before swallowing — they should never be swallowed intact. The injectable form is given by intravenous infusion in a clinical setting, only when oral dosing is temporarily not possible.
- Oral solution should be measured with a calibrated device, not a household spoon.
- Doses may be gradually increased over time — follow your prescriber's schedule.
- Never stop levetiracetam abruptly; always taper under your doctor's guidance to avoid withdrawal seizures.
- If you have kidney problems, your dose may need to be adjusted — your prescriber will determine the right amount for you.
🤒Side effects — in detail▾
The most common side effects with levetiracetam include:
- Drowsiness or sleepiness
- Weakness or fatigue
- Dizziness
- Headache
- Irritability, mood changes, or aggression (especially in children)
- Decreased appetite
- Nasal congestion or runny nose
- Infection
More serious reactions — including severe allergic reactions (anaphylaxis, angioedema), major skin reactions, psychotic symptoms, and suicidal thoughts — require immediate medical attention. Contact your doctor or go to an emergency room if you notice any of these.
⚠️Warnings & precautions▾
- Mood and behavior changes: Levetiracetam can cause irritability, aggression, anxiety, depression, and — rarely — psychotic symptoms like hallucinations. Children may be especially affected. Monitor closely and report any concerning changes to your doctor.
- Suicidal thoughts: Antiepileptic drugs including levetiracetam have been associated with increased risk of suicidal thinking and behavior. Seek help immediately if you or someone you care for experiences these thoughts.
- Serious skin and allergic reactions: Rare but potentially life-threatening reactions — including anaphylaxis (severe whole-body allergic reaction), angioedema (swelling of the face or throat), serious rashes, and DRESS (a multi-organ hypersensitivity reaction) — have been reported. Stop the medication and get emergency care if these occur.
- Drowsiness and coordination problems: Levetiracetam can impair your ability to drive or operate machinery, especially early in treatment. Wait until you know how it affects you before doing these activities.
- Do not stop suddenly: Stopping levetiracetam abruptly can cause withdrawal seizures. Always taper the dose under a doctor's supervision.
- Pregnancy: Blood levels of levetiracetam can drop during pregnancy, particularly in the third trimester, and the dose may need monitoring and adjustment.
🔀What it interacts with▾
Levetiracetam has a low risk of major drug interactions, but there are a few things to be aware of:
- Other antiepileptic drugs (carbamazepine, phenobarbital, phenytoin, primidone, etc.): Enzyme-inducing antiepileptics may modestly increase how quickly your body clears levetiracetam, but this generally does not require a dose adjustment.
- Valproate, lamotrigine, gabapentin, topiramate: Levetiracetam does not significantly affect blood levels of these drugs, and they do not meaningfully affect levetiracetam levels.
- Probenecid (used for gout): Can raise blood levels of levetiracetam's main metabolite (breakdown product), though the clinical significance is uncertain.
- Warfarin (blood thinner), digoxin (heart medication), and oral contraceptives: Levetiracetam does not significantly affect how these drugs work or their blood levels.
This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.
📋Before taking it▾
- Do not take levetiracetam if you have ever had a serious allergic reaction (anaphylaxis or angioedema) to it.
- Tell your doctor if you have kidney disease — the dose may need to be reduced, and patients on dialysis may need supplemental doses.
- Older adults are more likely to have reduced kidney function and should be monitored carefully during treatment.
- Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Levetiracetam levels can fall during pregnancy, especially in the third trimester, and dose adjustment may be needed. Levetiracetam passes into breast milk; weigh the risks and benefits with your doctor.
- Tell your doctor about any personal or family history of depression, anxiety, or other mental health conditions.
- Spritam and levetiracetam tablets for oral suspension are not recommended for children weighing 20 kg or less — the oral solution is preferred for smaller children.
- Elepsia XR is not recommended for patients with moderate or severe kidney impairment.
- Do not drive or use heavy machinery until you know how levetiracetam affects your alertness and coordination.
🚑If you take too much▾
Taking too much levetiracetam can cause severe drowsiness, agitation, aggression, decreased level of consciousness, slowed breathing, and in serious cases, coma. There is no specific antidote. If you suspect an overdose, contact a Poison Control Center immediately or go to an emergency room. Hemodialysis (kidney dialysis) can remove a significant portion of levetiracetam from the body and may be considered in serious overdose situations.
📡Pharmacodynamics — effects in the body▾
Studies of levetiracetam injection at various doses showed no meaningful effect on the QTc interval — a measure of the heart's electrical rhythm — meaning it does not appear to cause dangerous heart rhythm changes at therapeutic doses. This was confirmed in a controlled study of healthy subjects.
🔬Pharmacokinetics — how your body processes it▾
Levetiracetam is rapidly and almost completely absorbed when taken by mouth. Equivalent doses of the oral and intravenous forms produce the same blood levels, meaning they are bioequivalent when the IV form is given as a 15-minute infusion. The drug is not significantly bound to proteins in the blood, which reduces the likelihood of interactions that work through protein displacement. Its behavior in the body is predictable and consistent, with low variability between patients and over time.
📦How to store it▾
Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) .
📄 Written from Levetiracetam’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →
Supplements & herbs that interact with Levetiracetam
105 supplements and herbal products have documented interactions with Levetiracetam in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 7
- Moderate · 82
- Minor · 16
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Nutrient depletion considerations
Levetiracetam has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.
Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.
🩺 Pharmacist Counseling Corner
Quick, plain-English answers to the questions patients ask most about Levetiracetam — the kind of thing our pharmacy team would talk through with you at the counter.
What is levetiracetam actually used for? ▾
Will levetiracetam make me feel tired or foggy? ▾
I've heard this medication can affect your mood. Should I be worried? ▾
Can I just stop taking it if I feel fine and haven't had a seizure in a while? ▾
Is levetiracetam safe to take during pregnancy? ▾
Does levetiracetam interact with my other medications? ▾
Is Levetiracetam available over the counter? ▾
When was Levetiracetam first available? ▾
Who makes Levetiracetam? ▾
💬 Answers drafted from Levetiracetam’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →
🧰 Keep exploring
💊 How Levetiracetam comes
Levetiracetam is available in 4 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Tablet
How this form is used
- Keppra tablets treat partial-onset seizures in patients 1 month of age and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+)
- Roweepra treats partial-onset seizures in patients 1 month and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+)
- Spritam treats partial-onset seizures in patients 4 years and older weighing more than 20 kg, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+)
- Levetiracetam tablets treat partial-onset seizures in patients 4 years and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+)
- Spritam is designed to disintegrate in the mouth — place on the tongue with a sip of liquid and swallow only after it breaks apart; do not swallow Spritam tablets whole
- Spritam tablets may also be dispersed in a small amount of liquid in a cup before swallowing the entire contents immediately
- Spritam can be given through a nasogastric or gastrostomy feeding tube
- For pediatric patients weighing 20 kg or less, the oral solution is recommended instead of tablets
Injection
How this form is used
- Keppra injection treats partial-onset seizures in patients 1 month and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+) — for intravenous use only when oral dosing is temporarily not possible
- Levetiracetam injection treats partial-onset seizures in patients 1 month and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+) — for intravenous use only when oral dosing is temporarily not possible
- Levetiracetam in Sodium Chloride injection is approved for adults (16 years and older) for partial-onset seizures, myoclonic seizures in juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures — when oral dosing is temporarily not feasible
- All injectable forms are for intravenous use only — not for other routes of injection
- Levetiracetam in Sodium Chloride injection should not be diluted before use and is administered intravenously over 15 minutes
- When switching between oral levetiracetam and the injection, the total daily dose and frequency should remain the same
Show 2 more strengths Show fewer strengths
Oral solution
How this form is used
- Keppra oral solution treats partial-onset seizures in patients 1 month and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+)
- Levetiracetam oral solution treats partial-onset seizures in patients 1 month and older, and as add-on therapy for myoclonic seizures (age 12+) and primary generalized tonic-clonic seizures (age 6+)
- The oral solution is recommended for pediatric patients weighing 20 kg or less
- Always use a calibrated measuring device to measure the oral solution — do not use a regular household teaspoon or tablespoon
- For children, dosing is based on body weight — follow your prescriber's instructions exactly
Extended-release tablet
How this form is used
- Elepsia XR is approved as add-on therapy for partial-onset seizures in patients 12 years and older
- Keppra XR is approved for partial-onset seizures in patients 12 years and older
- Levetiracetam ER is approved for partial-onset seizures in patients 12 years and older
- Elepsia XR, Keppra XR, and Levetiracetam ER extended-release tablets are taken once daily
- Swallow extended-release tablets whole — do not chew, break, or crush them
- Elepsia XR is not recommended for patients with moderate or severe kidney impairment; the dose is limited in patients with mild kidney impairment
- Keppra XR and Levetiracetam ER doses must be individualized based on kidney function — follow your prescriber's guidance
📊 Levetiracetam across the U.S. market
How Levetiracetam appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Also listed with the FDA, not a patient dose form: Powder (35) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
📈 How widely Levetiracetam is used
A general measure of how commonly Levetiracetam is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Levetiracetam is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Levetiracetam prescribed? Of the 1,596 medications we measure, Levetiracetam ranks #72 by Medicaid prescriptions — more than 95% of them.
Utilization by Levetiracetam product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
levetiracetam 500 MG Oral Tablet Most dispensed
Summed across the 27 of 194 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 311289
levetiracetam 100 MG/ML Oral Solution
Summed across the 12 of 121 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 403884
levetiracetam 1000 MG Oral Tablet
Summed across the 16 of 99 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 387003
levetiracetam 750 MG Oral Tablet
Summed across the 23 of 96 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 311290
levetiracetam 250 MG Oral Tablet
Summed across the 22 of 113 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 311288
24 HR levetiracetam 500 MG Extended Release Oral Tablet
Summed across the 7 of 50 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 807832
24 HR levetiracetam 750 MG Extended Release Oral Tablet
Summed across the 8 of 36 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 846378
5 ML levetiracetam 100 MG/ML Injection
Summed across the 19 of 50 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 647121
100 ML levetiracetam 10 MG/ML Injection
Summed across the 9 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1193358
100 ML levetiracetam 15 MG/ML Injection
Summed across the 8 of 28 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1193360
100 ML levetiracetam 5 MG/ML Injection
Summed across the 7 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1193362
levetiracetam 500 MG Tablet for Oral Suspension
Summed across the 1 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1736048
levetiracetam 1000 MG Tablet for Oral Suspension
Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1736037
levetiracetam 250 MG Tablet for Oral Suspension
Summed across the 1 of 6 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1736045
levetiracetam 750 MG Tablet for Oral Suspension
Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1736051
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Levetiracetam, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 162 of 862 listed Levetiracetam NDCs with Medicaid activity.
🔍 Compare Levetiracetam products
A representative set of FDA-listed product records for Levetiracetam — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Injection | ||||
| 100 mg/mL | Intravenous | Armas Pharmaceuticals Inc. × 2 listings | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | Aryeh Pharma corp | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Athenex Pharmaceutical Division, LLC. | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Athenex Pharmaceutical Division, LLC. | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Athenex Pharmaceutical Division, LLC. | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | AuroMedics Pharma LLC | ANDA | View NDC → |
| 500 mg/100 mL | Intravenous | AuroMedics Pharma LLC | ANDA | View NDC → |
| 1000 mg/100 mL | Intravenous | AuroMedics Pharma LLC | ANDA | View NDC → |
| 1500 mg/100 mL | Intravenous | AuroMedics Pharma LLC | ANDA | View NDC → |
| 5 mg/mL | Intravenous | B. Braun Medical Inc. | ANDA | View NDC → |
| 10 mg/mL | Intravenous | B. Braun Medical Inc. | ANDA | View NDC → |
| 15 mg/mL | Intravenous | B. Braun Medical Inc. | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Baxter Healthcare Corporation × 2 listings | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Baxter Healthcare Corporation × 2 listings | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Baxter Healthcare Corporation | ANDA | View NDC → |
| 15 mg/mL | Iontophoresis | Baxter Healthcare Corporation | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Baxter Healthcare Corporation | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | Bryant Ranch Prepack | ANDA | View NDC → |
| 500 mg/100 mL | Intravenous | Caplin Steriles Limited | ANDA | View NDC → |
| 1000 mg/100 mL | Intravenous | Caplin Steriles Limited | ANDA | View NDC → |
| 1500 mg/100 mL | Intravenous | Caplin Steriles Limited | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Civica, Inc. × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Dr.Reddy's Laboratories Inc × 2 listings | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Dr.Reddy's Laboratories Inc × 2 listings | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Dr.Reddy's Laboratories Inc × 2 listings | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | Eugia US LLC | ANDA | View NDC → |
| 500 mg/100 mL | Intravenous | Eugia US LLC × 2 listings | ANDA | View NDC → |
| 1000 mg/100 mL | Intravenous | Eugia US LLC × 2 listings | ANDA | View NDC → |
| 1500 mg/100 mL | Intravenous | Eugia US LLC × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Fresenius Kabi USA, LLC × 2 listings | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Fresenius Kabi USA, LLC × 2 listings | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Fresenius Kabi USA, LLC × 2 listings | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Fresenius Kabi USA, LLC × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Gland Pharma Limited × 2 listings | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Gland Pharma Limited × 2 listings | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Gland Pharma Limited × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Hikma Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Hikma Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Hikma Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Hikma Pharmaceuticals USA Inc. × 5 listings | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Hospira, Inc. × 8 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Hp Halden Pharma AS | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Hp Halden Pharma AS | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Hp Halden Pharma AS | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Jubilant Cadista Pharmaceuticals Inc. | ANDA | Find on DailyMed ↗ |
| 500 mg/5 mL | Intravenous | Method Pharmaceuticals, LLC | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Micro Labs Limited × 4 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Mylan Institutional LLC × 2 listings | NDA | View NDC → |
| 10 mg/mL | Intravenous | Mylan Institutional LLC × 2 listings | NDA | View NDC → |
| 15 mg/mL | Intravenous | Mylan Institutional LLC × 2 listings | NDA | View NDC → |
| 100 mg/mL | Intravenous | Mylan Institutional LLC × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Nexus Pharamaceuticals Inc. × 2 listings | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Nexus Pharamaceuticals Inc. × 2 listings | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Nexus Pharamaceuticals Inc. × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Nexus Pharmaceuticals LLC | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Nexus Pharmaceuticals LLC | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Nexus Pharmaceuticals LLC | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | Novadoz Pharmaceuticals LLC × 2 listings | ANDA | View NDC → |
| 500 mg/5 mL | — | Patheon Italia S.p.A. | DRUG FOR FURTHER PROCESSING | View NDC → |
| 100 mg/mL | Intravenous | Precision Dose, Inc. × 2 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Sagent Pharmaceuticals | ANDA | View NDC → |
| 10 mg/mL | Intravenous | Sagent Pharmaceuticals | ANDA | View NDC → |
| 15 mg/mL | Intravenous | Sagent Pharmaceuticals | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | Sagent Pharmaceuticals × 2 listings | ANDA | View NDC → |
| 500 mg/5 mL | Intravenous | Solco Healthcare US, LLC × 2 listings | ANDA | View NDC → |
| 500 mg/100 mL | Intravenous | Somerset Therapeutics, LLC | ANDA | View NDC → |
| 1000 mg/100 mL | Intravenous | Somerset Therapeutics, LLC | ANDA | View NDC → |
| 1500 mg/100 mL | Intravenous | Somerset Therapeutics, LLC | ANDA | View NDC → |
| 100 mg/mL | Intravenous | TAGI Pharma, Inc. × 2 listings | ANDA | View NDC → |
| 100 mg/mL | Intravenous | UCB, Inc. × 3 listings | NDA | View NDC → |
| 5 mg/mL | Intravenous | WG Critical Care, LLC × 7 listings | NDA | View NDC → |
| 10 mg/mL | Intravenous | WG Critical Care, LLC × 5 listings | NDA | View NDC → |
| 15 mg/mL | Intravenous | WG Critical Care, LLC × 3 listings | NDA | View NDC → |
| 500 mg/5 mL | Intravenous | XGen Pharmaceuticals DJB, Inc. × 3 listings | ANDA | View NDC → |
| 💊Oral solution | ||||
| 100 mg/mL | Oral | ACI Healthcare USA, Inc. × 2 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | Actavis Pharma, Inc. × 3 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | Akorn × 2 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | American Health Packaging × 3 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | Amneal Pharmaceuticals LLC × 3 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | Apnar Pharma Lp | ANDA | View NDC → |
| 100 mg/mL | Oral | Atlantic Biologicals Corp. × 3 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | Aurobindo Pharma Limited × 3 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | AvPAK | ANDA | View NDC → |
| 100 mg/mL | Oral | Bionpharma Inc. | ANDA | View NDC → |
| 100 mg/mL | Oral | Breckenridge Pharmaceutical, Inc. | ANDA | View NDC → |
| 100 mg/mL | Oral | Bryant Ranch Prepack × 5 listings | ANDA | View NDC → |
| 100 mg/mL | Oral | Camber Pharmaceuticals, Inc. × 2 listings | ANDA | View NDC → |
| 500 mg/5 mL | Oral | Cardinal Health | ANDA | View NDC → |
| 100 mg/mL | Oral | Cardinal Health 107, LLC | ANDA | View NDC → |
| 💊Bulk drug substance | ||||
| 1 kg/kg | — | American Pacific Corporation | BULK INGREDIENT | View NDC → |
| 50 kg/50 kg | — | Aurobindo Pharma Limited | BULK INGREDIENT | View NDC → |
| 1 g/g | — | AX Pharmaceutical Corp | BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING | View NDC → |
| 25 kg/25 kg | — | Chieron Active Ingredients Private Limited | BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING | View NDC → |
| 1 g/g | — | Darmerica, LLC | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Divi's Laboratories Limited × 2 listings | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Dr.Reddy's Laboratories Limited | BULK INGREDIENT | View NDC → |
| 25 kg/25 kg | — | Emnar Pharma Private Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Esteve Quimica, SA | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Granules India Limited | DRUG FOR FURTHER PROCESSING | View NDC → |
| 1 kg/kg | — | Hetero Labs Limited × 2 listings | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Honour Lab Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | IOL Chemicals and Pharmaceuticals Ltd. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Jubilant Biosys limited | BULK INGREDIENT | View NDC → |
| 1 g/g | — | Letco Medical, Llc | BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING | View NDC → |
| 1 g/g | — | Medisca Inc. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | MSN Life Sciences Private Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Neuland Laboratories Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Professional Compounding Centers of America | BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING | View NDC → |
| 25 kg/25 kg | — | Professional Compounding Centers of America | BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING | View NDC → |
| 1 kg/kg | — | Professional Compounding Centers of America dba PCCA | BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING | View NDC → |
| 1 kg/kg | — | Rui Laboratories private limited | BULK INGREDIENT | View NDC → |
| 25 kg/25 kg | — | Shaoxing Jingxin Pharmaceutical Co., Ltd. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | SMS Pharmaceuticals Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Solara Active Pharma Sciences Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Srini Pharmaceuticals Private Limited | BULK INGREDIENT | View NDC → |
| 25 kg/25 kg | — | Sun Pharmaceutical Industries, Inc. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | UCB Farchim S.A. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | UCB Pharma S.A. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Wanbury Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Zhejiang Huahai Pharmaceutical Co., Ltd. × 2 listings | BULK INGREDIENT | View NDC → |
Showing 200 of 856 products — FDA National Drug Code Directory. See every product, package size and price: browse all 856 Levetiracetam NDCs →
📈 What people report — real-world data (FDA FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Levetiracetam — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Levetiracetam in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
🏛️ The road to your pharmacy
How Levetiracetam went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
🚨 Recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
Source: openFDA drug enforcement (recall) reports.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 114477 5 dose forms · 18 strengths
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Dose form (SCDF) Extended Release Oral Tablet RxCUI 807831In current FDA listingsClinical drug / strength (SCD) 24 HR levetiracetam 1000 MGRxCUI 160536224 HR levetiracetam 1500 MGRxCUI 160537224 HR levetiracetam 500 MGRxCUI 80783224 HR levetiracetam 750 MGRxCUI 846378 -
Dose form (SCDF) Injection RxCUI 1790330In current FDA listingsClinical drug / strength (SCD) 5 ML levetiracetam 100 MG/MLRxCUI 64712150 ML levetiracetam 5 MG/MLRxCUI 2585478100 ML levetiracetam 10 MG/MLRxCUI 1193358100 ML levetiracetam 15 MG/MLRxCUI 1193360100 ML levetiracetam 5 MG/MLRxCUI 1193362 -
Dose form (SCDF) Oral Solution RxCUI 406121In current FDA listingsClinical drug / strength (SCD) 100 MG/MLRxCUI 403884 -
Dose form (SCDF) Oral Tablet RxCUI 374617In current FDA listings -
Dose form (SCDF) Tablet for Oral Suspension RxCUI 1869554In current FDA listings
Look up RxCUI 114477 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
📦 Supply & shortage status
Whether Levetiracetam is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
🏷️ Sold under these brand names
🏭 Manufacturers & labelers
…and 16 more on the FDA NDC directory.
RxNorm drug class
Levetiracetam belongs to the Other antiepileptics class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
🔬 Where this comes from
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How we combine label and product data
HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 141 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.
For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Prasco Laboratories is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.
This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.