Drug & supplement interaction

Andiroba + Niraparib, Abiraterone

Niraparib, Abiraterone brand name: Akeega.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Andiroba and Niraparib, Abiraterone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Niraparib, Abiraterone states a food rule worth keeping to.

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Interaction report

Andiroba and Niraparib, Abiraterone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Niraparib, Abiraterone and Andiroba in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Andiroba safety at a glance

Andiroba overall Use caution Generally used on the skin; safety of taking it internally is not well studied.
Pregnancy Avoid Not enough safety data; best to avoid during pregnancy.
Breastfeeding Avoid Not enough safety data; best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Niraparib, Abiraterone and Andiroba? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Niraparib, Abiraterone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Niraparib, Abiraterone is filed under 5 classifications — including cytochrome p450 2d6 (cyp2d6) inhibitors, hepatotoxic drugs, cytochrome p450 3a4 (cyp3a4) substrates. Andiroba has documented interactions with 1 drug class — the most serious being anticonvulsants (minor) — and none of Niraparib, Abiraterone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Andiroba Does Interact With Other Medications

Andiroba has 50 minor known drug interactions in our database — Niraparib, Abiraterone isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Andiroba

Covers the 2,830 medications we’ve checked against Andiroba. Pick one to open its full report.

What to actually watch for

What Niraparib, Abiraterone’s Own FDA Label Lists

This is not an interaction — none of it involves Andiroba. These are the most notable effects listed in the ADVERSE REACTIONS section of Niraparib, Abiraterone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Bone thinning Worth acting on
  • Severe muscle breakdown Worth acting on
  • Muscle weakness Worth acting on
  • Low blood sugar Worth acting on
  • Low potassium Worth acting on
  • Blood clots Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Heart failure Worth acting on
  • An irregular heartbeat Worth acting on
  • A low platelet count Worth acting on

Showing the 10 most notable of 36 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Niraparib, Abiraterone. Read the label on DailyMed › Andiroba’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Andiroba side to compare — that is a limit of the record, not a statement that Andiroba has no side effects.

How to take them

Some Niraparib, Abiraterone Products Have a Food Rule — Andiroba Should Not Break It

At least one FDA label for a product containing Niraparib, Abiraterone says to take it on an empty stomach. Most supplements — Andiroba included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Niraparib, Abiraterone on its own and move Andiroba to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Niraparib, Abiraterone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.2 ) Take AKEEGA on an empty stomach at least one hour before or two hours after food.

From the Dosage and Administration section of the FDA label we read for Niraparib, Abiraterone — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Niraparib, Abiraterone

This page covers Andiroba only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Niraparib, Abiraterone page lists 171 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 128 moderate · 37 minor.

From our pharmacist’s overview on the Niraparib, Abiraterone page

“Men taking Akeega (niraparib and abiraterone) for prostate cancer often reach for supplements for fatigue, sleep, or general wellness, and this is a medication where those choices deserve genuine scrutiny. Of the 171 ingredients on file, 121 can change how the body clears the drug through the CYP3A4 pathway, either pushing levels towar…”

Reviewed by 2 · Jul 18, 2026

Open the Niraparib, Abiraterone interaction page

How much people look this up

Where Andiroba and Niraparib, Abiraterone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Andiroba
Steady interest

#825 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Niraparib, Abiraterone
Steady interest

#1,911 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Andiroba is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Andiroba reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Andiroba and Niraparib, Abiraterone records this page draws on were last updated July 3, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Andiroba

What is Andiroba?

Andiroba
  • Skin care and wound healing
  • Insect repellent
  • Muscle and joint aches
  • Anti-inflammatory skin conditions
  • Hair and scalp care

Andiroba is an oil pressed from the seeds of an Amazonian tree, used mainly on the skin for inflammation, minor wounds, aches, and as an insect repellent. Most evidence comes from laboratory and animal studies, so its benefits in people are not well proven. It is most often used topically; avoid internal use and use during pregnancy or breastfeeding because safety has not been established.

Carapa guianensis · Meliaceae · Seed oil (mainly), bark, and leaves · Topical oil, skin and hair products, soaps, balms, candles (insect repellent)

An interaction check asks whether these two react with each other — it does not ask whether Andiroba is a good idea for someone in your situation. Here is what our Andiroba record says about it on its own.

Andiroba: dosing

There is no established standard dose for andiroba. Doses have not been confirmed in reliable human studies.For topical products, follow the directions on the label.

From our Andiroba monograph — the full record covers uses, side effects and every documented interaction.

Read the full Andiroba monograph & all interactions
Keep checking

Other Drugs & Andiroba

Browse every other medication we’ve checked against Andiroba — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
50Minor
2,779No known interaction
Minor

50 interactions

No interaction 2,779 drugs checked — show the list
Evidence & sources

Andiroba References

The 3 sources that drive our Andiroba monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Andiroba is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Carapa guianensis (Andiroba) — U.S. National Library of Medicine (PubChem / NCBI) Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Using Dietary Supplements Safely — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Andiroba and Niraparib, Abiraterone Together: Common Questions

Is it safe to take Andiroba with Niraparib, Abiraterone?
We do not list a known interaction between Andiroba and Niraparib, Abiraterone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Andiroba and Niraparib, Abiraterone at the same time of day?
At least one FDA label for a product containing Niraparib, Abiraterone says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Niraparib, Abiraterone on its own and move Andiroba to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Andiroba and Niraparib, Abiraterone combination checked?
Interactions in our licensed database are recorded against drug classes. Niraparib, Abiraterone is filed under 5 classifications, and Andiroba has documented interactions with 1 drug class — none of Niraparib, Abiraterone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Andiroba interact with any other medications?
Yes. Andiroba has 50 documented drug interactions in our database — Niraparib, Abiraterone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Niraparib, Abiraterone interact with any supplements?
Yes. Niraparib, Abiraterone has documented interactions with 171 supplements in our database — Andiroba is not one of them. The Niraparib, Abiraterone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Niraparib, Abiraterone and Andiroba?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.