Drug & supplement interaction

Bael + Probenecid

Probenecid brand names: Benemid, Benuryl, Probecid.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Bael and Probenecid in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Bael and Probenecid

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Probenecid and Bael in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bael safety at a glance

Bael overall Use caution The ripe fruit is widely eaten as food, but concentrated supplements lack strong safety data.
Pregnancy Avoid Safety is not established and some traditional sources warn against medicinal use in pregnancy, so it is best avoided.
Breastfeeding Avoid There is not enough reliable information on safety while breastfeeding, so avoid medicinal use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Probenecid and Bael? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Probenecid

Interactions in our licensed database are recorded against drug classes, not just single drug names. Probenecid is filed under 6 classifications — including antigout drugs, organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates. Bael has documented interactions with 4 drug classes — the most serious being antidiabetes drugs (moderate), cholinergic drugs (moderate) and cytochrome p450 1a2 (cyp1a2) substrates (minor) — and none of Probenecid’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Bael Does Interact With Other Medications

Bael has 111 moderate, 708 minor known drug interactions in our database — Probenecid isn’t one of them. If you take anything else, check it against the full list below.

Moderate 111 Minor 708 No known interaction 2,011 (incl. Probenecid)
Taking anything else?

Check Another of Your Medications Against Bael

Covers the 2,830 medications we’ve checked against Bael. Pick one to open its full report.

What to actually watch for

What Bael Itself Has Been Linked To

This is not an interaction — nothing below involves Probenecid. It is the side-effect record for Bael on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Bael, this list is the first place to look.

  • Stomach upset / Constipation Additional detail

    “Consuming large amounts of bael may cause gastrointestinal upset and constipation (18).”

    Bael · Natural Medicines adverse-effect record, reported in constipation.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, consuming large amounts of bael may cause gastrointestinal upset and constipation (18).”

    Bael · Natural Medicines adverse-effect record, reported in constipation.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Bael — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Probenecid’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Probenecid column appears here.

From our Q&A

Questions About Bael or Probenecid

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Bael or Probenecid, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Probenecid

This page covers Bael only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Probenecid page lists 30 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 17 moderate · 10 minor.

From our pharmacist’s overview on the Probenecid page

“Probenecid does its work through the kidneys, pulling uric acid out of the blood to control gout, and that is exactly why the 30 supplement and herbal interactions on file deserve genuine care rather than a quick skim. The three rated major strike where this drug is most vulnerable: two are herbs, Siberian cocklebur among them, that ca…”

Reviewed by 2 · Jul 18, 2026

Open the Probenecid interaction page

One more smart check

Taking Bael as Part of a Dietary Supplement Product? Check It for Interactions

We hold 94 real supplement products containing Bael, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Bael. Even though Bael itself has no known interaction with Probenecid, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Bael and Probenecid Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bael
Top half

#455 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Probenecid
Steady interest

#1,998 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bael reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Bael and Probenecid records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bael

What is Bael?

Bael
  • Diarrhea and dysentery
  • Indigestion and other digestive complaints
  • Constipation
  • Blood sugar support
  • General wellness in traditional medicine

Bael is a fruit-bearing tree long used in traditional Indian (Ayurvedic) medicine, mostly for digestive problems like diarrhea and indigestion. Modern human evidence for its medicinal benefits is very limited, so it should be viewed mainly as a food and traditional remedy rather than a proven treatment. Talk to your pharmacist or doctor before using bael as a supplement, especially if you are pregnant, breastfeeding, or have a health condition.

Aegle marmelos · Rutaceae · Fruit (ripe and unripe), leaves, root, and bark · Fruit pulp, juice, powder, dried fruit, tea, capsules, and traditional preparations

An interaction check asks whether these two react with each other — it does not ask whether Bael is a good idea for someone in your situation. Here is what our Bael record says about it on its own.

Bael: dosing

There is no well-established standardized dose for bael as a supplement. The right amount depends on the product, the part of the plant used, and how it is prepared.If you choose to use a bael product, follow the directions on the label and do not exceed the recommended amount.

From our Bael monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bael monograph & all interactions
Medication

About Probenecid

What Is Probenecid Used For?

Brand names: Benemid, Benuryl, Probecid

Probenecid tablets are used to treat hyperuricemia (high uric acid levels in the blood) associated with gout and gouty arthritis. By helping the kidneys remove more uric acid, it lowers uric acid levels over time and helps prevent painful gout attacks.

Probenecid tablets are also used alongside certain penicillin-type antibiotics — including penicillin, ampicillin, methicillin, oxacillin, cloxacillin, and nafcillin — to raise and sustain the antibiotic's level in the bloodstream, making the antibiotic work more effectively.

See full Probenecid drug information
Keep checking

Other Drugs & Bael

Browse every other medication we’ve checked against Bael — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
111Moderate
708Minor
2,010No known interaction
111 Moderate 708 Minor 2,010 No interaction
Moderate

111 interactions

Showing 60 of 111 moderate interactions — see all 111 on the Bael page.

Minor

708 interactions

Showing 60 of 708 minor interactions — see all 708 on the Bael page.

No interaction 2,010 drugs checked — show the list

We also checked Bael against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,010 medications checked with no known interaction — see the full Bael list.

See the full Bael interactions page
See every supplement checked against Probenecid, ranked by severity
Evidence & sources

Bael References

The 7 references that drive our Bael monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Sabu, M. C. and Kuttan, R. Antidiabetic activity of Aegle marmelos and its relationship with its antioxidant properties. Indian J Physiol Pharmacol 2004;48(1):81-88.
  3. Kesari, A. N., Gupta, R. K., Singh, S. K., Diwakar, S., and Watal, G. Hypoglycemic and antihyperglycemic activity of Aegle marmelos seed extract in normal and diabetic rats. J Ethnopharmacol 10-11-2006;107(3):374-379. PubMed
  4. Haider, R., Khan, A. K., Aziz, K. M., Chowdhury, A., and Kabir, I. Evaluation of indigenous plants in the treatment of acute shigellosis. Trop.Geogr.Med 1991;43(3):266-270.
  5. Asaduzzaman M, Uddin MJ, Kader MA, et al. In vitro acetylcholinesterase inhibitory activity and the antioxidant properties of Aegle marmelos leaf extract: implications for the treatment of Alzheimer's disease. Psychogeriatrics. 2014;14(1):1-10.
  6. Yugandhar P, Rao KM, Sengupta K. A novel herbal composition containing extracts of Boswellia serrata gum resin and Aegle marmelos fruit alleviates symptoms of asthma in a placebo controlled double-blind clinical study. Phytother Res. 2018;32(1):140-150.
  7. Manda VK, Avula B, Chittiboyina AG, Khan IA, Walker LA, Khan SI. Inhibition of CYP3A4 and CYP1A2 by Aegle marmelos and its constituents. Xenobiotica. 2016;46(2):117-25.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bael and Probenecid Together: Common Questions

Is it safe to take Bael with Probenecid?
We do not list a known interaction between Bael and Probenecid. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Bael and Probenecid combination checked?
Interactions in our licensed database are recorded against drug classes. Probenecid is filed under 6 classifications, and Bael has documented interactions with 4 drug classes — none of Probenecid's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Bael interact with any other medications?
Yes. Bael has 819 documented drug interactions in our database — Probenecid is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Probenecid interact with any supplements?
Yes. Probenecid has documented interactions with 30 supplements in our database — Bael is not one of them. The Probenecid interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Bael monograph Uses, safety profile, and every drug interaction in one place Probenecid drug information The full plain-English guide to this medication Probenecid supplement interactions Every supplement checked against Probenecid, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 7 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Probenecid and Bael?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.